ライフサイエンスコーパス: oligomer

1 g structure dynamics within a single protein oligomer.

2 ational annealing process led to the desired oligomer.

3 ngage multiple sites in a single target homo-oligomer.

4 ikely contribute to the C2B interface in the oligomer.

5 elC assembles into a 12- subunit ring-shaped oligomer.

6 ges that promote assembly of a high-activity oligomer.

7 transcription factors function after forming oligomers.

8 rm compositionally and topologically diverse oligomers.

9 which respectively destabilize and stabilize oligomers.

10 ert-butylethyl)glycine (Ns1tbe) peptoid homo-oligomers.

11 cated the presence of mannose in each of the oligomers.

12 op a procedure for sequencing unknown lignin oligomers.

13 imitations in discerning the order of larger oligomers.

14 hesis, which we show is selective for higher oligomers.

15 % of APJ molecules were present as dimers or oligomers.

16 this paper were validated using fluorescent oligomers.

17 lasma membrane facilitates assembly of mVP40 oligomers.

18 ges rather than information about individual oligomers.

19 ly monomeric and K101C/E107C is dominated by oligomers.

20 peptide that does not self-assemble to form oligomers.

21 due to microstructural differences among the oligomers.

22 anine nucleotides and form rod-shaped hetero-oligomers.

23 She1 can also self-assemble into ring-shaped oligomers.

24 er's disease, is not detectable in the small oligomers.

25 inhibition of the putative neurotoxic Abeta oligomers.

26 ve assignments for the dominant motif in the oligomers.

27 Hsp27 12-mer, representative of larger Hsp27 oligomers.

28 hosphatidylinositol monophosphates and forms oligomers.

29 e formation of the putative neurotoxic Abeta oligomers.

30 determines the size of the resultant hetero-oligomers.

31 ry and secondary structure of soluble NFGAIL oligomers.

32 olecules found in the virus could form large oligomers.

33 ate structural models of the diverse protein-oligomers.

34 IR) light on synaptic vulnerability to Abeta oligomers.

35 roscopy to elucidate how EGCG remodels Abeta oligomers.

36 c parameter that sets the free energy of the oligomers.

37 lized over 2-3 porphyrin units in the linear oligomers.

38 absorption spectra measured by our group for oligomers (1, 2, and 3 units) of PTB7.

39 For analyte systems we investigated DNA oligomers (3-HPA), phospholipids (dithranol, THAP, HABA)

40 the synthesis of arylborane molecules 4a-c, oligomers 8a,b, and polymers 8a',b'.

41 In the shorter oligomers, a thiophene unit is attached to one or two co

42 Abeta oligomers (AbetaOs) are synaptotoxins that build up in t

43 neuronal dysfunction induced by amyloid-beta oligomers (AbetaOs).

44 buted to synaptotoxicity of the amyloid-beta oligomers (AbetaOs).

45 ngly, the solid state structure of the mixed oligomer Ac-(tBu)2-(s1tbe)4-(tBu)2-COOtBu, the longest t

46 inhibitor inhibited c-Abl activation and tau oligomer accumulation.

47 ere has been controversy about what types of oligomers actually confer these AD-like phenotypes.

48 was responsible for the accumulation of tau oligomers after TBI, as post-TBI injection of a calpain-

49 lar phases promote predominantly off-pathway oligomers, albeit via subtly different mechanisms.

50 ntimicrobial N-substituted glycine (peptoid) oligomers ("ampetoids") are structural, functional and m

51 d with structural rearrangements between the oligomer and fiber states.

52 sociating protein tau (MAPT, tau) into toxic oligomers and amyloid deposits is a primary pathology in

53 lf-assembly of alpha-synuclein (alphaS) into oligomers and amyloid fibrils is well established, the a

54 ases, which corresponded to the formation of oligomers and amyloid fibrils, respectively.

55 eta peptide (Abeta) misfolds into neurotoxic oligomers and assembles into amyloid fibrils.

56 es emerge naturally from the growing peptide oligomers and create environments suitable both to nucle

57 ctural changes occurring in both Abeta(1-40) oligomers and EGCG during remodeling offer a foundation

58 zes structural features common to both Abeta oligomers and fibril ends and that this interaction coul

59 forming toxic aggregates, including soluble oligomers and fibrillar amyloid deposits, which are link

60 nomeric alpha-synuclein into beta-sheet-rich oligomers and fibrils is associated with multiple neurod

61 sembly of tau and amyloid beta proteins into oligomers and fibrils.

62 t is transduced into the recruitment of TatA oligomers and into the actual translocation event.

63 arsenical hairpin binder) to detect soluble oligomers and mature fibrils formed from recombinant alp

64 expression and inflammasome activation (ASC oligomers and mature IL-1beta).

65 Moreover, antibodies which bind the oligomers and neutralize the cytotoxicity were exclusive

66 ign and synthesis of amide-linked saccharide oligomers and polymers, which are predisposed to fold in

67 apeutics targeting Aha1 may reduce toxic tau oligomers and slow or prevent neurodegenerative disease

68 Suc in the mesophyll and (2) segregation of oligomers and the inverted gradient of total sugar conte

69 cell-surface receptor, which binds to Abeta oligomers and transduces their toxic effects.

70 e-specific production of dA* in nucleic acid oligomers and/or polymers and also for the production of

71 ns of each conformation class differed among oligomers, and most oligomers contained 10-12 subunits o

72 ggest that toxicity is a property of soluble oligomers, and not large insoluble aggregates.

73 proteins and cell surface receptors are homo-oligomers, and thus can potentially be targeted by geome

74 ative dissociation into low molecular weight oligomers ( approximately 8-70 kDa), and these were now

75 KCTD12/KCTD16 hetero-oligomers are abundant in the hippocampus, where they pr

76 In NMR studies, oligomers are assembled using inter-protomer distance re

77 The properties of these oligomers are discussed, including their spontaneous sel

78 Instead, amyloid p53C oligomers are formed that can act as seeds nucleating de

79 our findings suggest that newly formed prion oligomers are infectious.

80 tions indicate that presumably soluble hIAPP oligomers are one of the cytotoxic species in type II di

81 How such oligomers are selectively sorted out of the Golgi is unk

82 ight species, and these low molecular weight oligomers are significantly more bioactive on synapses a

83 Fibrils and oligomers are the aggregated protein agents of neuronal

84 dence suggests that the highly dynamic Abeta oligomers are the main causal agent associated with the

85 n vitro, these two sHSPs form a polydisperse oligomer array composed solely of heterodimers, suggesti

86 n implementation of neutralized chimeric DNA oligomer as a probe for sensitive detection of single nu

87 loped to efficiently eliminate toxic Abeta42 oligomers as a promising treatment strategy for AD.

88 xamined the usage of the newly characterized oligomers as an active immunization agent targeting amyl

89 e the use of self-assembling type I collagen oligomers as an injectable therapeutic delivery vehicle

90 steps in the disassembly process generating oligomers as intermediates.

91 esponds to an alteration in desmin dimer and oligomer assembly and its connection with membrane prote

92 Our results show that pre-formed oligomers associate more efficiently with BBMV from Gene

93 , whereas it forms inactive disulfide-bonded oligomers at neutral pH that are caused by activation an

94 TIA1 also inhibited the accumulation of tau oligomers at the expense of increasing neurofibrillary t

95 association between mPPCs and Abeta monomer/oligomers based on circular dichroism and Thioflavin T f

96 We found that Abeta oligomer binding to CNS synaptosomes isolated from wild

97 nductance results suggested that Abeta(1-42) oligomers, but not monomers and fibers, formed three dis

98 rane proteins are known to form higher-order oligomers, but the degree to which membrane regions coul

99 r confident identification of the individual oligomers by slowly ramping the probe temperature and co

100 In addition, the oligomer can cross through the veins and enter the apopl

101 We demonstrate that the poison oligomers can act as habit modifiers both during the ini

102 results demonstrate that endogenous alphaSyn oligomers can impair memory by selectively lowering syna

103 ively appending monomers to a growing serial oligomer chain.

104 es indicates that newly formed SDS resistant oligomers change in size over time and lysates made from

105 y identified a novel therapeutic target: DAT oligomer complexes.

106 y we also synthesized and analyzed two mixed oligomers composed of NtBu and Ns1tbe monomers.

107 types of discrete, semicrystalline block co-oligomers, comprising an amorphous oligodimethylsiloxane

108 to describe amyloid aggregation predict low oligomer concentrations and do not take into account fre

109 ptor by assembling monomers into 6- to 8-mer oligomers; condensation of the preassembled oligomers in

110 ion class differed among oligomers, and most oligomers contained 10-12 subunits of the three dominant

111 l structure, evolves into ordered beta-sheet oligomers containing at least 5 strands, and then partia

112 commonly assumed to be the function of OPA1 oligomers containing both L- and S-OPA1.

113 -exposure of hydrophobic residues in Abeta42 oligomers contributes to the different aggregation pathw

114 These short oligomers convert to more closely packed membrane nanopo

115 onic hot spots of individual gold nanosphere oligomers, corroborated by open-shell density functional

116 Picomolar concentrations of Abeta42 oligomers could be observed to induce Ca(2+) influx, whi

117 ting the idea that conformational strains of oligomers could be significant in phenotypic outcomes.

118 igomerization, which suggests that large A3G oligomers could block HIV-1 reverse transcriptase-mediat

119 AnCDA acts on chito-oligomers, crystalline chitin, chitosan, and acetylxylan

120 Here, a series of oligomers d(XGiXC5X) and d(XC5XGiX) (X = A, T or none; i

121 Our results indicate that oligomers derived from cellulose are perceived as signal

122 suggests that Abeta trimers and higher-order oligomers derived from trimers have special significance

123 presence of poly(I:C), suggesting that LGP2 oligomers disperse so that LGP2 can bind MDA5.

124 Our data suggest that oligomer dissociation and increased flexibility of the d

125 interactions can occur both with and without oligomer dissociation.

126 ow that the oligomers leading to the type of oligomer distributions observed in experiments originate

127 We identified a set of six oligomers (DNA-carbon assemblies, DNA-CAs) with exceptio

128 using a broad approach, we quantified Abeta oligomers during the evolution of cognitive deficits in

129 Thus, Abeta oligomer elimination by RD2 treatment may be also benefi

130 "metal-free" A-D-A (acceptor-donor-acceptor) oligomer emitting in the near-infrared (NIR) thanks to d

131 Oligomers equipped with a sequence of phenol and pyridin

132 he spin over 2-3 porphyrin units for all the oligomers, except the 12-porphyrin nanotube, in which th

133 an Exhaustive Search algorithm for Symmetric Oligomer (ExSSO), which can perform near-complete search

134 A new family of pi-conjugated oligomers featuring a nonplanar polycyclic aromatic hydr

135 aments to folded monomers, dimers, and small oligomers, followed by diffusion of these species, and r

136 s in live cells demonstrate that KCTD hetero-oligomers form at least tetramers and that these tetrame

137 loxide precursors: no coordination of CO and oligomer formation during the polymerization of ethylene

138 Transiently populated oligomers formed en route to amyloid fibrils may constit

139 rectional, degrading 2-5 nucleotide long RNA oligomers from the 3' end, and longer RNA substrates fro

140 culation; (b) injection of gata1a morpholino oligomer (gata1aMO) suppressing hematopoiesis and result

141 show that the more-extended variants of each oligomer generally exhibit increased beta-sheet content.

142 nd controversy about what types and sizes of oligomers have disease-relevant activity.

143 Soluble Abeta42 aggregation intermediates (oligomers) have emerged as being particularly neurotoxic

144 t from the formation of low molecular weight oligomers, high molecular weight oligomers, protofibrils

145 We discovered that sHsps, which form large oligomers (HspB1/Hsp27, HspB3, HspB4/alphaA-crystallin,

146 te: (i) AUC data demonstrate the presence of oligomers; (ii) mutational analysis reveals a trans-argi

147 iments demonstrate that KCTD12/KCTD16 hetero-oligomers impart unique kinetic properties on G-protein-

148 KCTD12/KCTD16 hetero-oligomers impart unique kinetic properties to GABAB rece

149 s to its subunit locations within each GroEL oligomer in our dataset.

150 ave proposed a structural model for the TatA oligomer in which TatA monomers self-assemble using elec

151 that the KCTD proteins also assemble hetero-oligomers in all possible dual combinations.

152 ry1AcMod bound specifically and still formed oligomers in BBMV from both strains.

153 d in opposite outcomes, with build-up of Tau oligomers in enlarged auto-lysosomes.

154 Importantly, the abundance of alphaSyn oligomers in human brain tissue correlated with cognitiv

155 ons, we show that freely aggregating Abeta40 oligomers in physiological solutions have an intramolecu

156 were found to form stable monodisperse homo-oligomers in solution, and 15 (four homodimers, six homo

157 fer between fluorophores located in separate oligomers in the two-dimensional bilayer.

158 ulosic biomass, contains high energy density oligomers in the water-insoluble fraction that can be ut

159 ts multiple membrane phospholipids and forms oligomers in their presence.

160 of rice and agave Rca form functional hetero-oligomers in vitro, but only the rice isoforms denature

161 Mcm10 forms oligomers in vitro, mediated by the coiled-coil domain a

162 mic reticulum and that JMJD8 forms dimers or oligomers in vivo.

163 re)biologically relevant molecules and their oligomers, in a single-pot aqueous environment.

164 M imaging, in solution, show that over time, oligomers increase in size and number and release in sol

165 dings and indicate that KCTD12/KCTD16 hetero-oligomers increase the duration of slow IPSCs.

166 tin pool is in filamentous form as diffusing oligomers, indicating that severing and debranching are

167 We also infer that small molecules can alter oligomer-induced toxicity by modulating the aggregation

168 Here, we measured APJ monomer-homodimer-oligomer interconversion by monitoring APJ dynamically o

169 e three protomers, generating two asymmetric oligomer intermediates according to the scheme (SU-TM)3

170 oligomers; condensation of the preassembled oligomers into large clusters containing hundreds of mon

171 lignin, cellulose, and hemicellulose-derived oligomers into liquid alkanes with high efficiency and y

172 facilitates the reduction of cytosolic NPR1 oligomers into monomers, which enter the nucleus and fun

173 Abeta) by remodeling seeding-competent Abeta oligomers into off-pathway seeding-incompetent Abeta ass

174 An anionic phenylene ethynylene oligomer is initially quenched by water, producing minim

175 The resulting 11-13 capped oligomer is used by the PB1 polymerase subunit to initia

176 We show that dispersion of oligomers is concomitant with reduced cocaine intake, an

177 tate delocalization in linear zinc porphyrin oligomers is explored by electron paramagnetic resonance

178 secting the communication mechanisms in homo-oligomers is identifying intermediate liganded states, w

179 yloid polypeptide (IAPP) to form fibrils and oligomers is important in the progression of type 2 diab

180 ting binding of amyloid beta (Abeta) and tau oligomers is one of the earliest impairments in Alzheime

181 structures of these trimers and higher-order oligomers is paramount for understanding their role in n

182 Human calprotectin (CP, S100A8/S100A9 oligomer) is a metal-sequestering host-defense protein t

183 es in directly meso-to-meso linked porphyrin oligomers lead to localization of the photoexcited tripl

184 ecular dynamics simulations to show that the oligomers leading to the type of oligomer distributions

185 ease and then attenuate as a function of the oligomer length.

186 amyloid plaques likely sequester soluble HMW oligomers, limiting their potential to dissociate.

187 ol-maleimide coupling to synthesize discrete oligomers/macromolecules on a gram scale with molecular

188 he transient nature and heterogeneity of the oligomers make it difficult to follow their structure.

189 Thus, the perception of cellulose-derived oligomers may participate in cell wall integrity surveil

190 so equally effective in inhibiting preformed oligomer-mediated processes.

191 ABCC2 facilitates Cry1Ac oligomerization and oligomer membrane insertion in P. xylostella.

192 We hypothesize that these oligomers might form high-spin states in their reduced f

193 Seven synthesized G-lignin oligomer model compounds (ranging in size from dimers to

194 ison to ROA spectra calculated for different oligomer models.

195 Our data therefore support that KCTD hetero-oligomers modulate physiologically induced K(+) current

196 S/MS results showed that the isolated mannan oligomers, MOS-III, MOS-IV, MOS-V and MOS-VI consist of

197 In solution, these oligomers neither readily convert into mature fibrils no

198 ydisperse, polymorph, and compact oligomers (oligomer number n = 2-13) as well as extended intermedia

199 We compared association of pre-formed Cry1Ac oligomer, obtained by incubating Cry1Ac toxin with a Man

200 cretin complex of Thermus thermophilus is an oligomer of the 757-residue PilQ protein, essential for

201 ndrons and can be thought of as monodisperse oligomers of a single amphiphile.

202 SIGNIFICANCE STATEMENT: Oligomers of amyloid beta-protein (oAbeta) are tought to

203 Soluble oligomers of amyloid beta-protein (oAbeta) isolated from

204 Low molecular weight oligomers of amyloid-beta (Abeta) have emerged as the pr

205 Cyclic oligomers of azole peptides were isolated from a multitu

206 to the difference between the composition of oligomers of free FtsZ-GDP and free FtsZ-GTP formed in s

207 the distribution of dimers and higher-order oligomers of K-Ras4B, the most frequently mutated Ras is

208 t GABAB receptors also associate with hetero-oligomers of KCTD subunits.

209 hat Slack currents are rapidly suppressed by oligomers of mutant human Cu/Zn superoxide dismutase 1 (

210 We find that injection of oligomers of mutant superoxide dismutase 1 (SOD1) into t

211 Peptoids that are oligomers of N-substituted glycines represent a class of

212 Hetero-oligomers of TatB and TatC form circular substrate-recep

213 creasingly thought to be instigated by toxic oligomers of the amyloid beta peptide (AbetaOs).

214 Soluble oligomers of the amyloid-beta peptide (AbetaOs) are thou

215 Oligomers of the beta-amyloid peptide Abeta have emerged

216 Our data reveal that oligomers of the fibril-forming peptide segments VEALYL

217 the components were spontaneously generated oligomers of the original compound.

218 lls, and identify the formation of oxidative oligomers of the sensors in the ER.

219 r-infrared absorption spectra of excitons in oligomers of the ubiquitous conjugated polymers poly(3-h

220 highly polydisperse, polymorph, and compact oligomers (oligomer number n = 2-13) as well as extended

221 fects of Abeta fibrils and brain-derived tau oligomers on AD-related gene expression and to interroga

222 zation of purified single-stranded DNA probe oligomers on cleaned gold microelectrodes.

223 RY2) can form light-regulated CRY2-CRY2 homo-oligomers or CRY2-CIB1 hetero-dimers, but modulating the

224 h subsequent generation of the corresponding oligomers or higher-order structures.

225 onclude that conditions that destabilize HMW oligomers or retard the sequestration of their smaller,

226 in SOD1 that cause the enzyme to form toxic oligomers, our findings suggest that suppression of Slac

227 may cross-link Tie2 dimers into higher-order oligomers, potentially explaining how Tie2 is differenti

228 heterotypic interactions between pre-amyloid oligomers prevent the homotypic interactions that would

229 ular weight oligomers, high molecular weight oligomers, protofibrils, and fibrils.

230 We posit that these soluble prefibrillar oligomers provide a missing link in our understanding of

231 gests that synaptic malfunction due to Abeta oligomers rather than plaque pathology is decisive for d

232 sus (with a few exceptions) that off-pathway oligomers, rather than amyloid fibrils, are the toxic sp

233 however, the existence of APJ homodimers and oligomers remains to be investigated.

234 Well-defined, fused-ring aromatic oligomers represent promising candidates for the fundame

235 levels of potentially toxic alpha-synuclein oligomers, resulting in conformationally and functionall

236 ed classification of the 14 subunits in each oligomer revealed three dominant classes of subunit conf

237 ity-determining region, crenezumab binds the oligomer's lateral and edge residues.

238 Importantly off-pathway oligomers saturate within a limited molecular size, and

239 Data support a new model where an LGP2-MDA5 oligomer shuttles NS3 to the mitochondria to block antiv

240 for injecting quickly-polymerizing collagen oligomer solutions into mice to form a collagen-fibril m

241 he algorithm is able to generate approximate oligomer solutions quickly as initial inputs for further

242 y available web servers predict protein homo-oligomer structures either by template-based modeling us

243 In homo-oligomers, subunits establish communication pathways tha

244 n-2 binding disrupted pre-assembled nectin-2 oligomers, suggesting that receptor-ligand and ligand-li

245 ped for tasks that include sequence-specific oligomer synthesis and the switching of product chiralit

246 iting in combination with massively parallel oligomer synthesis can enable trackable editing on a gen

247 tron transfer occurring in single nanosphere oligomer systems with a 3% yield, a phenomenon unobserve

248 either by template-based modeling using homo-oligomer templates selected from the protein structure d

249 Many foldamers, oligomers that adopt well-defined secondary structures,

250 But, for oligomers that are higher than dimer, these distance res

251 This results in soluble low-molecular-weight oligomers that can act as a therapeutic agent in vitro a

252 ort a general approach to design cyclic homo-oligomers that employs a new residue-pair-transform meth

253 ly be targeted by geometrically matched homo-oligomers that engage all subunits simultaneously to att

254 itions causes IRE1alpha to form higher-order oligomers that exhibit continuous activation and extende

255 Oligomers that have a H-bond donor and acceptor on the e

256 lein, and promoted the accumulation of toxic oligomers that impaired neuronal synaptic transmission.

257 bilized trimers assemble in solution to form oligomers that recapitulate some of the higher-order ass

258 y typically assemble into large polydisperse oligomers that vary in both size and shape but are princ

259 We also show that upon binding Abeta(1-40) oligomers the relative positions of the EGCG B and D rin

260 For each oligomer, the UV spectra exhibit distinct changes in the

261 gh both VKOR and VKORL form disulfide-linked oligomers, the cysteine residues involved in the oligome

262 For a particular alphaSyn oligomer, these changes were either dependent or indepen

263 ation potential and propensity to form toxic oligomers, they represent particularly attractive target

264 at the Ml proteins studied form higher-order oligomers through their N-terminal region and that the s

265 ith one neurabin molecule in a neurabin homo-oligomer to form a ternary complex, representing a novel

266 monomer units during the transition from the oligomer to the fibril form.

267 e structural transition of the small Abeta40 oligomers to fibrils.

268 monomers, dimers, tetramers to higher order oligomers to generate a double strand break in DNA.

269 can subsequently recruit additional prepore oligomers to grow the pore size.

270 cteristics that enable toxic alpha-synuclein oligomers to perturb biological membranes and disrupt ce

271 hese resulted in improved memory in AbetapE3 oligomer-treated mice.

272 Rather, these oligomers undergo an alpha-helix to beta-sheet conversio

273 acyl hydrazide functionalities into peptide oligomers via solid-phase copper-catalysed azide-alkyne

274 The chimeric DNA oligomer was synthesized in a conventional DNA synthesiz

275 eating, the increase of dimers, trimers, and oligomers was observed.

276 ion of long term potentiation (LTP) by Abeta oligomers was prevented.

277 can be applied to any rotationally symmetric oligomers, was validated using the structures of the Fas

278 Pairwise interactions between the oligomers were investigated using NMR titration and dilu

279 erization upon ephrinA1 stimulation, but the oligomers were larger than those observed for EphA2FL-GF

280 These prefibrillar CysC oligomers were potent inhibitors of aggregation of the A

281 in meso-to-meso ethyne or butadiyne-bridged oligomers, where the preferred dihedral angles amount to

282 by encouraging the formation of prefibrillar oligomers, whereas adding the C-terminal polyproline seq

283 ay confirmed the presence of bona fide Abeta oligomers, whereas immunoprecipitation-Western blotting

284 -helical cytotoxic islet amyloid polypeptide oligomers which interact with cell membranes, following

285 me product, likely Mn(IV)(mu-O)2Mn(IV) or an oligomer, which subsequently nucleates MnO2 nanoparticle

286 a on the number and distribution of receptor oligomers, which is beyond the quantitative power offere

287 lysis supports the simultaneous formation of oligomers, which represent 10-60% of the product.

288 emarkably reduced the level of intracellular oligomers while modestly reduced the level of an inflamm

289 as a mixture of monomers, dimers and larger oligomers, while the K101E mutant is predominantly monom

290 ation also affects the association of Cry1Ac oligomer with the membrane.

291 mensional NMR reveals that suitably designed oligomers with >20% modified backbones can form native-l

292 h those of earlier measurements on porphyrin oligomers with alkyne linkers exhibiting different prefe

293 e dimers assemble into high-molecular-weight oligomers with an apparent two-fold symmetry, which are

294 tal-free method for construction of discrete oligomers with tailored structures and a high growth rat

295 by the substrate-induced association of TatA oligomers with this receptor.

296 were flavan-3-ols, flavan-3-ol monomers and oligomers, with an average degree of polymerization betw

297 y assemble into higher order homo- or hetero-oligomers within their natural lipid environment.

298 ered to lack helix alpha-1, was able to form oligomers without cadherinbinding and effectively counte

299 e, in physiological buffer, wt CysC can form oligomers without undergoing domain-swapping.

300 of a series of X-shaped pyromellitimide (PI) oligomers (Xn-R, n = 2-4, R = Hex or Ph) linked together