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1 ation, nitration, inactivation, and covalent oligomerization.
2 use model, we artificially enhanced alphaSyn oligomerization.
3 in regulating RR specificity, allostery, and oligomerization.
4 ing CRY2-CRY2 interaction prefer robust homo-oligomerization.
5 nhibits kinase activity by reducing receptor oligomerization.
6 Cry1Ac interaction with cadherin triggers oligomerization.
7 hology is through a major role of decreasing oligomerization.
8 t opening of the complex is prerequisite for oligomerization.
9 structures, and three are involved in DISC1 oligomerization.
10 namics that serves as a regulator for MFN1/2 oligomerization.
11 reover, G4 substrates induce cooperative AID oligomerization.
12 t relies on unfolded protein binding-induced oligomerization.
13 stereochemistry at the C3 carbon can induce oligomerization.
14 t the post-translational level by FRP and/or oligomerization.
15 Delta) mutation, which promotes amyloid-beta oligomerization.
16 y of tandem GFP11-tag in scaffolding protein oligomerization.
17 R1 at the plasma membrane and facilitate its oligomerization.
18 h Fam65b in stereocilia and regulates Fam65b oligomerization.
19 l GXXXG in putative TM2 is important for S1R oligomerization.
20 interactions are essential in preformed Tie2 oligomerization.
21 stable, well-folded and undergoes reversible oligomerization.
22 cofactor binding, allosteric activation and oligomerization.
23 cross-linked peptides, which indicated Atg18 oligomerization.
24 ped in a compact conformation preventing its oligomerization.
25 ng contacts with the minor groove of DNA and oligomerization.
26 d induce allosteric changes that lead to its oligomerization.
27 s much larger configurations consistent with oligomerization.
28 -36) monomer (2) interfere with Abeta(17-36) oligomerization (3) disrupt a pre-formed Abeta(17-36) pr
31 and S16) towards huntingtin exon 1 (HTTex1) oligomerization, aggregation and toxicity in human cells
32 mini and the hook region of beta1a prevented oligomerization, allowing for its structural determinati
33 -core motifs of this defensin that eliminate oligomerization also knockout its ability to induce memb
34 as screened to identify antagonists of Abeta oligomerization, amyloid formation, and cytotoxicity.
41 tamate formation increases the rate of Abeta oligomerization and alters the interactions of Abeta wit
42 h effector four-helical bundle of MLKL, (ii) oligomerization and association of MLKL with cellular me
43 ngth Spa47 point mutants, we find that Spa47 oligomerization and ATP hydrolysis are needed for comple
44 mational mutp53s bypass Akt to induce TopBP1 oligomerization and attenuate ATR checkpoint response du
46 nding site are required for PA-mediated NsD7 oligomerization and coil formation, as well as permeabil
48 ously undergo light-dependent CRY2-CRY2 homo-oligomerization and CRY2-CIB1 hetero-dimerization, both
49 ccepted role in aiding S-layer biogenesis or oligomerization and demonstrates a connection to cellula
50 of Roco proteins and suggests a link between oligomerization and disease-associated mutations in LRRK
54 LRP3 and AIM2 inflammasome by preventing ASC oligomerization and may be a potential therapeutic candi
57 l domain of A3G (A3G-CD1) is responsible for oligomerization and nucleic acid binding, both of which
58 he first time, that ABCC2 facilitates Cry1Ac oligomerization and oligomer membrane insertion in P. xy
59 ssome, determinants for RNA binding, subunit oligomerization and processive UTP incorporation, and pr
61 21-mediated p62 ubiquitylation abrogates p62 oligomerization and sequestration of proteins including
62 -dependent p53 modulation requires both auto-oligomerization and tandem-BRCT domain-mediated bivalent
63 ze that sHsp chaperone efficiency depends on oligomerization and that client interactions can occur b
65 T-23, which promotes actin-dependent dynamin oligomerization and thus, increases actin polymerization
66 of the lipid membrane composition on protein oligomerization and to observe structural changes in pro
67 orrect membrane insertion, tertiary folding, oligomerization, and biochemical modification of the new
68 ciated speck-like protein with a CARD domain oligomerization, and caspase-1 processing, key events du
69 tivation of HK activity via homo- and hetero oligomerization, and cross-phosphorylation between HKs.
71 ynamin function and couple membrane binding, oligomerization, and GTPase activity during dynamin-cata
72 on constrain AtHIR1 dynamics, promote AtHIR1 oligomerization, and increase the efficiency of the inte
73 essibility of Abeta1-42 at various stages of oligomerization, and provides new insights on site-speci
77 intracellular amyloid-beta accumulation and oligomerization are early AD pathologic processes, which
78 In addition, neurabin domains required for oligomerization are essential for formation of the A1R/n
80 s the current state of our knowledge of MDM2 oligomerization as well as current efforts to target the
81 A (e.g., matrix and nucleocapsid) impact Gag oligomerization as well as immature particle size and mo
82 disrupt bifurcated substrate recognition or oligomerization both compromise CSR in splenic B cells.
83 Notably, ligand binding also induces EGFR oligomerization, but the structures and functions of the
84 y, consistent with netrin-1-induced receptor oligomerization, but with no change in aggregation state
85 nd to strongly impact on protein folding and oligomerization by altering the hydrogen bond network.
86 we analyzed Cry1Ac and Cry1AcMod binding and oligomerization by western blots using brush border memb
87 in Nature Cell Biology, show how PAR protein oligomerization can dynamically couple protein diffusion
88 ling protocols, we further targeted ethylene oligomerization catalysis by Ni-AIM guided by theoretica
90 domain deletion (EphA2DeltaS-GFP) increases oligomerization compared to the full length receptor (Ep
92 ly phosphorylates ASC and brings ASC into an oligomerization-competent state by allowing Tyr146 phosp
93 in lipid bilayers and forms a viroporin upon oligomerization, confirmed by EIS conductance measuremen
95 nd oligomerization kinetics of wild-type and oligomerization-deficient A3G, and find that A3G first t
96 ersisted, but trans-allostery was lost in an oligomerization-deficient GLUT1 variant in which we subs
97 either alanine or glutamine severely reduces oligomerization, demonstrating the role of protonated E7
100 masome, by members of the nucleotide-binding oligomerization domain (Nod), leucine-rich repeat-contai
101 ponse pathways, including nucleotide-binding oligomerization domain (NOD)-, Toll-, and RIG1-like rece
103 ing 1 (NLRP1), NLRP3, and nucleotide-binding oligomerization domain (NOD)-like receptor C4 (NLRC4) we
105 mmation by activating the nucleotide-binding oligomerization domain (NOD)-like receptor protein 3 (NL
106 stem was not dependent on nucleotide binding oligomerization domain (NOD)-like receptors (NLRs), reti
110 PV) forms homotetramers composed of a stable oligomerization domain (Pcore) flanked by large intrinsi
111 cognition receptor, NOD2 (nucleotide-binding oligomerization domain 2), belongs to the innate immune
112 ymbiotic bacteria via the nucleotide-binding oligomerization domain containing 2 (Nod2) sensor in cel
113 trate that both TNF-R and nucleotide-binding oligomerization domain stimulation promote ATG16L1 stabi
115 table helices are formed C terminally to the oligomerization domain, extremely transient helices are
116 The inflammasome proteins nucleotide-binding oligomerization domain, leucine rich repeat and pyrin do
117 ceptor (IL-1R) family and nucleotide-binding oligomerization domain, leucine-rich repeat and pyrin do
118 se susceptibility protein nucleotide-binding oligomerization domain-containing 2 (NOD2); however, the
121 he innate immune receptor nucleotide-binding oligomerization domain-containing protein 2 (NOD2) is es
122 e signaling-3, rs4969170; nucleotide-binding oligomerization domain-containing protein 2, rs3135500;
123 n (CARD)-containing member of the nucleotide oligomerization domain-like receptor (NLR) family, was f
124 ne 1-like receptor (RLR), nucleotide-binding oligomerization domain-like receptor (NLR), and Toll-lik
127 and chemokine signaling, nucleotide-binding oligomerization domain-like receptor signaling and Janus
130 or components of the TLR, nucleotide binding oligomerization domain-like receptor, and retinoic acid-
131 matory processes, the nucleotide-binding and oligomerization domain-like receptor, leucine-rich repea
132 unity receptors, known as nucleotide-binding oligomerization domain-like receptors (NLRs), to recogni
136 t evidence indicates that nucleotide-binding oligomerization domains (NODs) can also recognize a broa
138 n the structure of the GabR effector-binding/oligomerization (Eb/O) domain suggest that binding a mon
139 Swi6 and Chp2 have similar dimerization and oligomerization equilibria, and that Swi6 binds slightly
142 Thus, we provide an approach to investigate oligomerization for arbitrary protein families leading t
144 tabolic regulation and apoptosis, where VDAC oligomerization has been implicated with these processes
146 , we demonstrate that the regulation of EHD2 oligomerization in a membrane-bound state is crucial to
147 of the traptamers with the EPOR induced EPOR oligomerization in an orientation that stimulated recept
149 transport within target cells, potential K28 oligomerization in the ER lumen is prevented by protein
152 studies demonstrate an essential role of FP oligomerization in vivo while our monomers enable detail
154 embrane binding and also reveals a potential oligomerization interface in the C-terminal domain as we
155 the C-terminal domain as well as a conserved oligomerization interface in the mVP40 N-terminal domain
156 eratively promoting and directing gamma-TuSC oligomerization into MT nucleation-competent rings.
157 ical analyses of human CCL5 reveal that CCL5 oligomerization is a polymerization process in which CCL
158 ere nucleosome assembly defects showing that oligomerization is essential for the chaperone function.
161 of the protein into oligomers and that SMSr oligomerization is promoted by curcumin, a drug known to
165 measure the single-stranded DNA binding and oligomerization kinetics of wild-type and oligomerizatio
166 ligomeric macrocyclic depsipeptides using an oligomerization/macrocyclization process governed by a s
167 en configurations and use it to construct an oligomerization map that captures the paths of easy inte
169 t hDAT might function as a multimer, and its oligomerization may be relevant to addictive drug effect
172 edge, for (19)F solid-state NMR distance and oligomerization measurements by centerband-only detectio
174 ctive role of the IF consensus motifs in the oligomerization mechanism of tetramers during ULF format
175 he modeling reveals that these two competing oligomerization mechanisms play distinct roles: polymeri
176 o different larval gut proteins facilitating oligomerization, membrane insertion and pore formation.
177 potential significance because more complex oligomerization might lead to differences in substrate s
179 The compound did not affect heat-induced oligomerization, nuclear localization and specific DNA b
180 on of nucleoprotein-core links nucleoprotein oligomerization, nucleocapsid condensation, RNA encapsid
186 Furthermore, the effect of lipid membrane on oligomerization of alpha-Syn is also investigated and th
192 demonstrated that PI(4,5)P2 also induces the oligomerization of ExoU and that this PI(4,5)P2-mediated
193 results indicate that PI(4,5)P2 induces the oligomerization of ExoU, which may be a mechanism by whi
195 erization of membrane-anchored FZD4 CRDs and oligomerization of full-length FZD4, which requires the
197 or, we confirmed that EVT901 interferes with oligomerization of full-length p75 neurotrophin receptor
199 ding factor; rather, its binding promoted de-oligomerization of Hsp27, likely by competing for the se
201 inding influences specificity, activity, and oligomerization of human RR, we aligned >300 eukaryotic
203 with a parallel study showing that covalent oligomerization of ILEI is essential for EMT and tumor p
204 C-terminal tail region of IN in higher order oligomerization of intasomes, potentially informing futu
205 the ER membrane to the nucleus by promoting oligomerization of IRE1, a conserved transmembrane ER st
206 that this pair of side chains could promote oligomerization of kalata B1 through electrostatic inter
207 lex recruitment to centromeres by regulating oligomerization of M18BP1 through the Mis18alpha:Mis18be
209 SLC25A46 results in increased stability and oligomerization of MFN1 and MFN2 on mitochondria, promot
211 l insights into approaches for examining the oligomerization of neurotransmitter transporters and she
216 It has previously been suggested that the oligomerization of SNARE complexes required for cooperat
219 s stabilized by a supramolecular, tetrameric oligomerization of the Ce horizontal lineO units with ru
220 ite sequence (first TMSOTf then Et3N) led to oligomerization of the cinnamyl SF5- and CF3-acetates.
222 rt that this alternating array underlies the oligomerization of the GIPC/Myosin VI complexes in solut
223 ,3]-sigmatropic rearrangement and subsequent oligomerization of the intermediately formed cinnamyl es
225 ally, we applied these insights to study the oligomerization of the luminal domains of two nuclear me
226 ncluding IL-1beta and IL-18, by inducing the oligomerization of the multiprotein complex NLRP3-type i
228 and in vivo assays, we can show that higher oligomerization of the scTNF trimers results in more eff
233 cREL, DeltaNp63alpha and TAp73 binding and oligomerization on NF-kappaB-, TP53- or AP-1-specific se
234 inding of DDX1 results in enhancement of Rev oligomerization on the RRE that is correlated with an RN
236 hese kinases may harbor regions that mediate oligomerization or control other aspects of signal trans
237 ns provide distinct contributions to Gag-Gag oligomerization, particle morphology, and biogenesis.
238 to provide distinct contributions to Gag-Gag oligomerization, particle morphology, and biogenesis.
239 he observed structural similarity and common oligomerization pathway between the two variants is like
241 , C-O bond formation, hydrolysis of silanes, oligomerization, polymerization, metathesis, hydrosilyla
242 fication of a translational switch affecting oligomerization presented here has implications for the
243 ET efficiency-lifetime analysis to probe the oligomerization process of intrinsically disordered prot
244 at the A- and B-inserts distinctly alter the oligomerization propensity of Drp1 in solution as well a
246 ation of these domains, coupled with dynamic oligomerization properties, is the basis for the remarka
247 using the blue light-sensitive dimerization/oligomerization property of A. thaliana Cryptochrome 2 (
248 of the protein, nor affects its stability or oligomerization property, however, it reduces the post-t
249 and CusC are connected to one another in an oligomerization ratio of 3:6:3 CusA/CusB/CusC to form th
251 ty of both its hydrogen atom abstraction and oligomerization reactions can be attributed to its very
252 1 CA NTD/HTLV-1 CA CTD did not result in Gag oligomerization regardless of the parent Gag background.
253 tion significantly impaired effector-induced oligomerization required for enzyme activity, and oligom
254 high and CRY2low with elevated or suppressed oligomerization respectively, which we use to tune the l
255 antly, specific interference with ETO2-GLIS2 oligomerization reverses the transcriptional activation
256 the effects of the substitutions on peptide oligomerization, secondary structure dynamics, fibril as
257 ere, we tested the model by variation of the oligomerization state and by increase of the number of G
258 ests that physicochemical properties such as oligomerization state and DNA specificity, although tune
261 e available for researchers to determine the oligomerization state of membrane proteins in a static q
262 TuRC assembly is critically dependent on the oligomerization state of Spc110p, with higher-order olig
264 tor interactions are highly dependent on the oligomerization state of the receptor, and cellular fact
265 Strikingly, however, irrespective of the oligomerization state or presence of additional GABs, fi
268 progesterone receptors) reveals variation in oligomerization states among this family of transcriptio
269 dual alpha-SYN protein and assess its native oligomerization states from biological samples including
270 cability of this approach by quantifying the oligomerization states of membrane proteins tagged with
271 luorescent particle concentration and assess oligomerization states of proteins within defined region
272 nezumab and CreneFab can recognize different oligomerization states; however, the structural basis fo
274 rylated at serine 149, which regulates G3BP1 oligomerization, stress granule assembly, and RNase acti
275 ured linker region of Cox15 needed for Cox15 oligomerization, suggesting that this region mediates th
277 identify small-molecule inhibitors of STOML3 oligomerization that reversibly reduce the sensitivity o
279 he role of cholesterol in chemokine receptor oligomerization, thereby promoting the formation of a si
280 ch interferes with p75 neurotrophin receptor oligomerization through direct interaction with the firs
281 inutes, the information-rich 4D space (x, y, oligomerization, time) results were coupled to straightf
282 Y2-CIB1 interaction desire minimal CRY2 homo-oligomerization to avoid unintended complications, while
286 ant, EphA2DeltaS-GFP, also underwent further oligomerization upon ephrinA1 stimulation, but the oligo
289 merization required for enzyme activity, and oligomerization was rescued in the N291G/P294K enzyme.
290 classes of structurally related families is oligomerization, wherein a series of enzymatically catal
291 Akt phosphorylates TopBP1 and induces its oligomerization, which inhibits its ATR-activating funct
292 Gag protein is a primary determinant of Gag oligomerization, which is a critical step for immature G
293 responses and inflammatory diseases via self-oligomerization, which leads to the activation of the pr
294 from a fast to a slow binding state through oligomerization, which suggests that large A3G oligomers
295 eversal mutation of apposed residues reduces oligomerization while introduction of cysteines at these
296 ase domain, which mediates cycles of protein oligomerization with caRNAs, in response to ATP binding
297 ver, two C-terminal charges impact CRY2 homo-oligomerization, with positive charges facilitating olig
299 that both XGh and XGo undergo fiber-to-fiber oligomerization without losing their crystallinity.
300 ed peptide binding to hIRE1alpha LD from its oligomerization, yet retained peptide-induced allosteric
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