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1 and a partially folded intermediate that can oligomerize.
2 vity, but 4 of the 8 retained the ability to oligomerize.
3 the related ATPase SERCA, PLM is reported to oligomerize.
4 er RHL2 with little tendency to further homo-oligomerize.
5 y inactive enzyme that is fully competent to oligomerize.
6 ctin is present in a protein complex and can oligomerize.
7 displays a markedly increased propensity to oligomerize.
8 motif (SAM) domain and shows a propensity to oligomerize.
9 n, and that the binding causes fibrinogen to oligomerize.
10 gether with the adjacent helical region homo-oligomerize.
11 interaction is lost when Cox15 is unable to oligomerize.
12 thetic challenge because of their ability to oligomerize.
13 activities are dependent on its capacity to oligomerize.
14 c stability of apoA-IV and its propensity to oligomerize.
15 veral MxB variants that lose the capacity to oligomerize.
16 onounced tendency of TatE and TatA to hetero-oligomerize.
17 in the Golgi apparatus and are able to homo-oligomerize.
18 Here we show that CARMA1 is constitutively oligomerized.
19 ncreased also, suggesting that Py-A54145 had oligomerized.
20 the strand segments are immobilized and thus oligomerized.
21 N1-N9) and the prior knowledge that a N1 TMD oligomerizes.
22 Here we show that AIM PYD (AIM2(PYD)) self-oligomerizes.
24 ide evidence that ARFs have the potential to oligomerize, a property that could be important for gene
27 the C-terminal polybasic PM-targeting motif oligomerized after Ca(2+) store depletion but failed to
28 Moreover, because all Bax molecules became oligomerized after membrane insertion, we infer that Bax
29 to GPP130 in the Golgi and causes GPP130 to oligomerize/aggregate, and the complexes are diverted to
30 IL are clustered on the exosomal membrane as oligomerized aggregates ready to form death-inducing sig
32 ese results are emphasized by simulations of oligomerized amphiphysin N-BARs at the atomistic and coa
35 in stromal interaction molecule 1 (STIM1) to oligomerize and accumulate within endoplasmic reticulum-
36 eases the concentration of TAB1-TAK1 and may oligomerize and activate TAK1 in a TAB1-dependent manner
37 RbAB translates into a propensity to rapidly oligomerize and aggregate at 37 degrees C (T50 = 28 min)
39 haliana CURT1 proteins (CURT1A, B, C, and D) oligomerize and are highly enriched at grana margins.
41 S remained or re-directed in the nucleus can oligomerize and behave similarly to the wild-type FUS pr
42 omerize upon GAG binding, and the ability to oligomerize and bind GAGs is required for in vivo functi
44 constitution with mutants of Bax that cannot oligomerize and form apoptotic pores, but still enhance
45 ype CORO1A in normal lymphocytes but did not oligomerize and had impaired cytoskeletal association.
47 on studies then revealed that these proteins oligomerize and interact through a dense network of cont
48 into the structural origin of its ability to oligomerize and interact with phospholipid bilayers, pro
49 demonstrated that ASB-Cullin 5 complexes can oligomerize and provides evidence that Cullin 5 forms he
50 f full-length NS1A from different strains to oligomerize and results in a reduction in dsRNA binding
51 l unclear, insight as to how these receptors oligomerize and the relevance of the lipid environment t
53 ot BAX) in lymphohematopoietic cell lines is oligomerized and bound to anti-apoptotic BCL2 family mem
60 which recognizes H3K9-methylated chromatin, oligomerizes and forms a versatile platform that partici
61 s: canonical holins, like lambda S105, which oligomerizes and forms large membrane holes of unprecede
62 ) is a model alpha-PFT from sea anemone that oligomerizes and forms pores in sphingomyelin-containing
63 ing in, the mitochondrial membrane, where it oligomerizes and is further activated, steps that are ne
64 provide a unique comparison set because CCL2 oligomerizes and oligomerization is required for its ful
65 s from the cytosol to mitochondria, where it oligomerizes and permeabilizes the mitochondrial outer m
66 these data support the hypothesis that EXP2 oligomerizes and potentially forms the putative membrane
69 enic despite their ability to bind ephrinB2, oligomerize, and associate with F at wild-type (WT) leve
70 ought to first bind to the membrane, then to oligomerize, and finally to detach, in a stringently reg
72 Ag, a portion of MBC receptors spontaneously oligomerized, and phosphorylated kinases accumulated at
73 t binds to cholesterol-containing membranes, oligomerizes, and forms a beta-barrel transmembrane pore
74 into the mitochondrial outer membrane (MOM), oligomerizes, and induces MOM permeabilization, causing
75 which Sec17 binds to trans-SNARE complexes, oligomerizes, and inserts apolar loops into the apposed
76 e show that the coiled-coil domain of AtZAR1 oligomerizes, and this domain acts as a signal to induce
77 a more favorable setting in which GPCRs can oligomerize as a prelude to nucleation and crystal growt
79 tion, pointing to the possibility that GerBC oligomerizes as a result of either high local protein co
81 tic protein RIBEYE suggest that monomers can oligomerize at the level of the IS before ribbon assembl
82 tant was still able to bind to membranes and oligomerize at the same level as the wild-type or the re
85 egions markedly impair the ability of p53 to oligomerize BAK and to induce transcription-independent
88 is is likely due to the inability of CCL7 to oligomerize because CCL2(P8A) also binds significantly l
89 and generality of this translation system by oligomerizing building blocks including polyethylene gly
91 nal self-diffusion rates indicate that CCL27 oligomerizes, but in contrast to many other chemokines t
92 mechanism by which yeast NAP1 (yNAP1) dimers oligomerize by applying x-ray crystallographic, hydrodyn
93 om the P subfamily (FoxP) show that they can oligomerize by three-dimensional domain swapping, whereb
95 ding studies with GpL-FLAG-TNC-TWEAK trimers oligomerized by help of a FLAG tag-specific antibody gav
98 This indicates that the higher activity of oligomerized CD95L trimers is not related to an avidity-
99 hought to mediate many cellular processes by oligomerizing cell surface glycoproteins and glycolipids
102 ominantly of three proteins that form highly oligomerized concentric rings spanning the inner and out
103 Our results suggest a physiological role for oligomerized condensin in driving gradual chromatin comp
112 uronal cell line, mild overexpression of the oligomerizing E57K alpha-Syn variant significantly impai
113 r nanocomplex is obtained by complexation of oligomerized EGCG with the anticancer protein Herceptin
116 We selected a green tea catechin derivative, oligomerized (-)-epigallocatechin-3-O-gallate (OEGCG) as
117 pendant sulfonate group that can bind to Pd, oligomerizes ethylene to a Schultz-Flory distribution of
119 rs were incubated in Mg(2+), they folded and oligomerized even further to produce hypercondensed high
120 identical aggregation mechanisms, the latter oligomerized faster due to lower solubility and, hence,
121 olecular pathways that involve dimerized and oligomerized fatty acid derivatives as key intermediates
124 sting that these substitutions may stabilize oligomerized forms of protegrin that are postulated to b
125 ling complexes ("signalosomes") assembled by oligomerizing hub proteins following their recruitment t
127 xperiments in HEK-293 confirm that NCS-1 can oligomerize in cell lysates and that oligomerization is
128 These results suggest that beta2ARs do not oligomerize in cells, and demonstrate a reliable method
131 tion.Moreover, the ability of the protein to oligomerize in solution was found to correlate with tran
132 and function as oligomers, but how monomers oligomerize in the cell membrane remains poorly understo
136 s evidence that purified full-length Syt1 is oligomerized in the membrane, and mutagenesis indicates
139 that this putatively monomeric mutant still oligomerizes in intact membranes but forms more dynamic
145 ere we show that the DEAD-box helicase Ded1p oligomerizes in the cell and in vitro, and unwinds RNA a
146 exin26 (Cx26) is a gap junction protein that oligomerizes in the cell to form hexameric transmembrane
147 RE1 activation are conserved: mammalian IRE1 oligomerizes in the ER membrane and oligomerization corr
151 bunits that are monomeric in the cytosol and oligomerize into a protein lattice only upon membrane bi
153 ilament, also has an intrinsic propensity to oligomerize into an elongated structure that activates t
156 larly to holins, CidA and LrgA were found to oligomerize into high-molecular-mass complexes whose for
158 Furthermore, the propensity of dynamin to oligomerize into higher-order structures in an actin-dep
159 mprise a family of GTP-binding proteins that oligomerize into higher-order structures, which associat
164 r journey as soluble monomeric proteins, and oligomerize into transmembrane complexes to eventually f
165 sion experiments indicate that penetratin is oligomerized into beta-sheets in gel-phase membranes.
166 the related nematode Caenorhabditis remanei oligomerizes into a decameric assembly that appears roug
167 pported by experimental data: first, dynamin oligomerizes into a helical polymer; second, dynamin oli
168 pon binding to cytochrome c and dATP, Apaf-1 oligomerizes into a heptameric complex known as the apop
170 th diverse cellular activities) protein that oligomerizes into single hexameric rings in the presence
173 kinesin-13s, KLP59D is largely incapable of oligomerizing into MT-associated rings in vitro, suggest
177 ce for a major increase in Fn14 occupancy by oligomerized ligand despite strongly enhanced induction
179 ed diffusion is due to conserved features of oligomerized MACPF proteins, which may include an anioni
181 nal studies showed that G51D alpha-synuclein oligomerizes more slowly and its fibrils are more toxic
182 type arrestin-1 in living animals with a non-oligomerizing mutant retaining all other functions.
183 uired for a specific interaction between the oligomerized NHR2 domain and a novel NHR2-binding (N2B)
185 ucleus, as well as inhibiting its ability to oligomerize, not only neutralizes NPM1 toxicity but also
187 virus encoding a mutant protein that cannot oligomerize on DNA, ICP8 microfoci are not detected; how
188 They are secreted as soluble monomers that oligomerize on target membranes in the so-called prepore
189 eleased as water-soluble monomers that first oligomerize on the membrane before inserting a transmemb
190 talytically active monomers or dimers slowly oligomerize on the viral genome and inhibit reverse tran
192 ges in the local environment of SP1 when Gag oligomerizes on nucleic acid might trigger this switch.
197 y other activities of soluble TWEAK, whereas oligomerized or FcgammaR-bound Fn14 antibodies fully mim
198 calized by MPO and then either spontaneously oligomerizes or binds to matrix proteins, all leading to
200 a in the neuropil and that this synaptotoxic oligomerized peptide is present at a subset of synapses.
201 Arabidopsis ADH1 and TT4 genes were made by Oligomerized Pool ENgineering (OPEN)-a publicly availabl
205 malignancies, regulate the ability of NS to oligomerize, prevent its degradation, and may alter its
206 equently, cIAP1 cooperatively interacts with oligomerized processed caspase-9 in the apoptosome and b
207 t preferentially self-assemble without cross-oligomerizing provides for controlled experiments to ana
208 show that CALM-AF10 has a propensity to homo-oligomerize, raising the possibility that the function o
210 ssed, but in the presence of its ligands, it oligomerizes, recruits apoptosis-associated speck-like p
213 have been derived from structural studies of oligomerized, RNA-encapsidating nucleoprotein, and cryo-
217 TNFR2 activation, we constructed differently oligomerized single chain TNF ligands (scTNF) comprised
220 er N terminus correlates with the ability to oligomerize, store iron, and form stable contacts with N
222 ms of protection induced by the treatment of oligomerized T cell epitope of myelin proteolipid protei
224 We furthermore show that diffusive JPO2 can oligomerize; that JPO2 and LEDGF/p75 interact directly a
227 Bacterial enhancer-binding proteins (bEBPs) oligomerize through AAA(+) domains and use ATP hydrolysi
228 at FGFR1OP2/wit3.0 were able to dimerize and oligomerize through coiled-coil structures and appeared
231 SWAP-70 is an F-actin-bundling protein that oligomerizes through a Gln/Glu-rich stretch within a coi
232 d that the transmembrane domain of FtsB homo-oligomerizes through an evolutionarily conserved interac
233 lacking all cytosolic domains (STIM1-DeltaC) oligomerizes through EF-SAM interactions alone, but thes
236 the interface of mTOR complex 1 dimer, which oligomerizes through two spatially separate interfaces.
237 rtially buried when CCL3, CCL4, and CCL5 are oligomerized; thus, the mechanism by which GAG binds the
238 inal truncated SAA2.2 (SAA2.2DeltaC) did not oligomerize to a hexamer or octamer, but formed a high m
239 e their ability to insert into membranes and oligomerize to create the large curvatures; however, the
240 cooperativity suggests that STIM1 must first oligomerize to enable its accumulation at ER-PM junction
241 during procapsid morphogenesis, 10 proteins oligomerize to form a DNA translocating conduit (H-tube)
242 y ATPases to date have one ATPase domain and oligomerize to form a functional molecular machine, most
244 proteins of about 110 residues that need to oligomerize to form a structural pathway for substrate e
246 self-associating protein building blocks can oligomerize to form discrete supramolecular assemblies u
249 In Schwann cells, connexin 32 (Cx32) can oligomerize to form intracellular gap junction channels
250 o through reactions in which capsid proteins oligomerize to form long tubes, and this process can be
251 p4 and any mixture of the 56- and 63-kDa gp4 oligomerize to form more hexamers than does the 63-kDa g
252 a class of pathogen-secreted molecules that oligomerize to form transmembrane channels in cellular m
254 ith DnaA contacting low affinity sites as it oligomerizes to 'fill the gaps' between high affinity si
255 of ER stress, the transmembrane protein Ire1 oligomerizes to activate its cytoplasmic kinase and ribo
256 -forming component, protective antigen (PA), oligomerizes to create a prechannel that forms toxic com
259 s lividans KcsA is a 160-aa polypeptide that oligomerizes to form a tetrameric potassium channel.
260 ere we show that the PhiX174 pilot protein H oligomerizes to form a tube whose function is most proba
261 Similar to other nacre proteins, rPFMG1 oligomerizes to form amorphous, heterogeneously sized pr
262 e attack complex/perforin (MACPF) domain and oligomerizes to form an aqueous pore in the plasma membr
263 a coli, a membrane-bound TatA complex, which oligomerizes to form complexes of less than 100 to more
264 (ORF54) gene encodes an 87-kDa monomer that oligomerizes to form the VZV portal protein, pORF54.
265 y adenosine triphosphates to unwind helices, oligomerizes to function as efficient RNA helicase, and
266 fted features only emerge when the ion pairs oligomerize together into larger (TOTA.[CS2BF4])n assemb
267 al IL8 production, more than 2500 cell-bound oligomerized TWEAK trimers were required to elicit a sim
270 upled receptors as monomers, many chemokines oligomerize upon GAG binding, and the ability to oligome
272 low measurements revealed that Atg18 rapidly oligomerizes upon membrane binding while it is mainly mo
274 nity similar to CCL2 but higher than the non-oligomerizing variant, CCL2(P8A), suggesting that, in co
279 experiments mimics the process by which VacA oligomerizes when in contact with membranes of host cell
280 e NTD charge density required more Mg(2+) to oligomerize, whereas mutants that increased the charge d
281 ependent membrane recruitment causes FGF2 to oligomerize, which in turn triggers the formation of a l
283 inactive variant (alphaKAP) that can hetero-oligomerize with and target active enzyme to membranes.
285 lasmic reticulum after synthesis, where they oligomerize with other binding partners, such as alpha a
286 ment of CLL cells with Wnt5a induced ROR1 to oligomerize with ROR2 and recruit guanine exchange facto
287 of which have an equal propensity to hetero-oligomerize with SEPT7-containing hexamers to generate o
288 phosphorylation of Smad2 and Smad3 that then oligomerize with Smad4 and translocate into the nucleus
290 ently split fragments of NiV, RSV, and MeV L oligomerized with comparable efficiency in all homo- and
296 onstrated that the PNKD long isoform monomer oligomerizes with itself as well as interacts with the s
297 2 homolog, also has a RING domain and hetero-oligomerizes with Mdm2 to stimulate its E3 ligase activi
298 death-domain-containing adaptor protein that oligomerizes with PIDD and caspase-2 to initiate apoptos
300 s show that the transmembrane helix of ADCK3 oligomerizes, with an interface based on an extended Gly
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