ライフサイエンスコーパス: oligopyrimidine

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1 ding of RPS mRNA via cis-acting, 5'-terminal oligopyrimidines.

2 translation rate of mRNAs whose 5' terminal oligopyrimidine (5' TOP) motif regulates the synthesis o

3 t being transcripts containing a 5' terminal oligopyrimidine (5' TOP) motif.

4 own to affect the translation of 5' terminal oligopyrimidine (5' TOP) tract mRNA, which encodes the t

5 n machinery mRNAs that possess a 5'-terminal oligopyrimidine (5'-TOP) motif in their 5'-UTR, includin

6 dine tract characteristic of the 5'-terminal oligopyrimidine (5'TOP) class of genes.

7 The 5'terminal oligopyrimidine (5'TOP) motif is a cis-regulatory RNA el

8 h a subset of mRNAs that contain 5'-terminal oligopyrimidine (5'TOP) motifs known to control protein

9 ' untranslated regions comprised of terminal oligopyrimidine (5'TOP) tracts and that encode ribosomal

10 y rapamycin are highly enriched for terminal oligopyrimidine and for very short 5' and 3' untranslate

11 S5 transcript is a member of the 5' terminal oligopyrimidine class of RNAs, which is specifically con

12 ble in serum-containing medium than standard oligopyrimidine-derived ODNs or ODNs derived from dT and

13 extremely stable triplex with an oligopurine/oligopyrimidine DNA duplex with Delta T m +14.3 degrees

14 Mutation of the oligopyrimidine element showed that it is essential to o

15 stimulates translation of the TOP (terminal oligopyrimidine motif) and TOP-like mRNAs, polysome-prof

16 nslation of a selective group of 5'-terminal oligopyrimidine mRNAs (encoding proteins involved in the

17 activation, affect double-strand cleavage at oligopyrimidine-oligopurine tracts on DNA.

18 Furthermore, the oligopyrimidine ribo N3'-->P5' phosphoramidate formed an

19 ii) inhibited translation of non-5'-terminal oligopyrimidine ribosomal protein mRNAs and ribosomal RN

20 Short oligopyrimidine RNAs formed on the CTCCTC allele could b

21 roughly 45-nucleotide window overlapping an oligopyrimidine sequence having counterparts in the lyti

22 n the mRNA encoding PABP contains a terminal oligopyrimidine (TOP) element found in mRNAs, the transl

23 methylation, but not mRNAs with 5' terminal oligopyrimidine (TOP) elements.

24 of transcripts with established 5' terminal oligopyrimidine (TOP) motifs, or, like Hsp90ab1 and Ybx1

25 f mTORC1 with a fundamental role in terminal oligopyrimidine (TOP) mRNA translation.

26 defined group of messengers called terminal oligopyrimidine (TOP) mRNAs which encode ribosomal prote

27 ZNF9 interacts with the 5' UTRs of terminal oligopyrimidine (TOP) tract mRNAs encoding human ribosom

28 ranslated region (UTR) containing a tract of oligopyrimidines (TOP).

29 s mRNA, which does not contain a 5'-terminal oligopyrimidine tract (5'-TOP), was translated earlier,

30 o ribosomal S6 protein phosphorylation and 5'oligopyrimidine tract (5'TOP)-encoded protein synthesis

31 luded or lay adjacent to the conserved 31-nt oligopyrimidine tract (referred to as the Y block), abol

32 In mammalian cells a 5'-terminal oligopyrimidine tract (TOP) is a conserved feature of th

33 protein and is known to regulate 5'-terminal oligopyrimidine tract (TOP) mRNA translation.

34 Class II consists of terminal oligopyrimidine tract (TOP) mRNAs that are regulated in

35 ferential translation of mRNAs containing an oligopyrimidine tract at the 5'-end of the message.

36 transcript demonstrates that it possesses an oligopyrimidine tract characteristic of the 5'-terminal

37 e), pathway and translation of a 5' terminal oligopyrimidine tract containing mRNA, Elongation factor

38 mal protein S6 and regulation of 5'-terminal oligopyrimidine tract mRNAs, is an important regulator o

39 the translation of mRNAs with a 5'-terminal oligopyrimidine tract such as eukaryotic elongation fact

40 , the translation of rpS8, an mRNA with a 5'-oligopyrimidine tract, did not coincide with rpS6 phosph

41 ranslation of mRNAs containing a 5'-terminal oligopyrimidine tract, our data suggest that transcripti

42 y the wild-type IRES is limited by its short oligopyrimidine tract.

43 A), the mRNA of which contains a 5' terminal oligopyrimidine tract.

44 sis factors and contain hallmark 5'-terminal oligopyrimidine tracts (5'TOP).

45 specific subset of mRNAs bearing 5'-terminal oligopyrimidine tracts (5'TOPs) by the structurally rela

46 n, which regulates translation of mRNAs with oligopyrimidine tracts in the 5'-untranslated region.

47 for initiation of translation for mRNAs with oligopyrimidine tracts in their 5' untranslated region.

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