ライフサイエンスコーパス: one step

1 stituted alpha-fluoroalkenyl pyrrolidines in one step.

2 newly created stereocenters at both ends in one step.

3 creening and diagnosis of V-HCV infection in one step.

4 unctional nanoemulsions and nanoparticles in one step.

5 into zygotes to generate modified animals in one step.

6 chiral alpha-hydroxyaldehyde derivatives in one step.

7 chiral aryl iodide, prepared in 94% yield in one step.

8 combined targeted capture and sequencing in one step.

9 epoxides affords 3,4-dihydroisocoumarins in one step.

10 an aryl migration, and a fluorination all in one step.

11 he generation of a valuable algae product in one step.

12 nsitions shifting the cleavable phosphate by one step.

13 with control of three-dimensional shape, in one step.

14 isolate microorganisms in axenic culture in one step.

15 ded a highly conjugated organic framework in one step.

16 opper-catalyzed 'click' reaction; and (ii) a one-step (18)F-labeling method that obviates the need fo

17 variety of aldehydes efficiently provide, in one step, access to 3-formyl-2-furylcarbinols, which are

18 Implementation of this procedure as a one-step, additive-free, and versatile protocol leads to

19 iointerfaces are designed in this study by a one step adsorption of HLM directly onto polished basal

20 In this study, we report a novel one-step aerosol process that not only extracts Si parti

21 targets as well, toward designing inhibitors one step ahead of evolution to counter resistance with m

22 affords 1,5-disubstituted 1,2,3-triazoles in one step and complements the more established copper-cat

23 les the formation of 2D and 3D structures in one step and high yield.

24 Herein, we demonstrate an easy operating one-step and low-cost way to synthesize egg-derived hete

25 This one-step and one-pot assay constitutes an improved alter

26 For this systematic review and one-step and two-step meta-analysis of individual partic

27 e (common feedstock), an enoate (prepared in one step) and B2 (pin)2 (commercially available) are pre

28 ation to form the 5,12-fused macrolactone in one step, and a gold-catalyzed Yu glycosylation to insta

29 5,7-fused ring system with an oxa-bridge in one step, and a stereoselective exo-Diels-Alder reaction

30 By one-step annealing sandwiched growth substrates (Ni(C)/(

31 This one-step approach combines the merits of discrimination

32 drogels has shown great promise, as a simple one-step approach, to generate multifunctional scaffolds

33 and bulk carbon nitride, was fabricated by a one-step approach.

34 device, including the capabilities of rapid, one-step assay performance, and high throughput producti

35 quantify the levels of the two bacteria in a one-step assay, without the need for DNA extraction or a

36 le cationic Co(III) catalyst for convergent, one-step benchtop syntheses of N-aryl-2H-indazoles and f

37 correlations, which are degree correlations one step beyond those of neighboring nodes, we accuratel

38 iazolylidenes is further demonstrated by the one-step bicyclization of 10-oxocitral to (racemic) nepe

39 ierarchical cross section can be prepared in one step by hollow fiber spinning, double mantle spinnin

40 ct preparation of fused N-heterotricycles in one step by intramolecular C-H amination or Pictet-Speng

41 The inhibitor can be synthesized in one step by multicomponent reaction (MCR) chemistry when

42 is used to prepare hybrid nanostructures in one step by triggering a programmable cascade of events

43 feature of this biosensing platform is that one step calcination process is enough to create the fun

44 low carbon onions have been synthesized by a one-step carbonization of metal-organic-framework ZIF-67

45 Ferrocenes undergo one-step carboxamidation by reaction with isocyanates in

46 g array of hollow or filled microchambers by one-step casting with small applied pressure and a PDMS

47 osphates, which were globally deprotected by one-step catalytic (Pd/C) hydrogenation/hydrogenolysis.

48 hripsis hypothesis suggests an extraordinary one-step catastrophic genomic event allowing a chromosom

49 A expression analysis of few single cells, a one-step cell lysis, target labelling and hybridisation

50 icrostructures have been synthesized through one-step chemical reduction of micron size Cu2O and Co3O

51 notube (BHCNT), has been synthesized using a one-step chemical vapor deposition process.

52 A one-step chronocoulometric method at 0.83 and 1.18 V for

53 Although the analytical simplicity of the one-step classical theory of nucleation facilitates its

54 es between pairs of laboratories to within a one-step classification difference and identified key so

55 genes simultaneously, we established simple one-step cloning approaches for expression of multiple s

56 ng ARMC9 mutations as a cause of JS takes us one step closer to a full genetic understanding of this

57 oteins into the system, this study brings us one step closer to biomimetic enamel regrowth.

58 stness of our model, which makes KCE methods one step closer to their practical use in selection of d

59 functionalities and takes the nanocomposites one step closer toward future nanoscale device integrati

60 edded, intelligent, brain-inspired computing one step closer.

61 changes in an individual's hemostatic state one step closer.

62 es with the current recommended dual therapy one step closer.

63 y brings these novel RNAi-based therapeutics one-step closer to clinical use.

64 The one-step codeposition process was carried out with binar

65 metric wettability are synthesized through a one-step compartmentalized growth of a mesoporous organo

66 idized PNA/DNA heteroduplexes merely through one-step conjugation in the presence of 1-ethyl-3-(3-dim

67 Moreover, one-step construction of imide and amide bonds with a lo

68 In vitro recombination methods have enabled one-step construction of large DNA sequences from multip

69 We present a one-step controllable chemical extraction of whole nucle

70 O/Al2O3@ZSM-5 core@shell catalyst active for one-step conversion of synthesis gas to dimethyl ether (

71 Here, we developed a one-step, cost-effective route to produce a novel biocom

72 A metal-free one step coupling reaction between various N-azole rings

73 highly efficient perovskite solar cell using one step CVD and there is likely room for significant im

74 ood to excellent yields via an unprecedented one-step cyclocondensation of 4H-pyrido[1,3]oxazin-4-one

75 rk to achieve optimal performance and solves one-step decision-making tasks, commonly considered in n

76 LFTs use a premix format for a rapid one-step delivery of premixed sample and labeled antibod

77 nditional and targeted-insertion alleles via one-step delivery of targeting components directly to zy

78 spersion, and 3) limitations associated with one-step deposition.

79 regio- and good stereoselectivities in only one step, deprotection affords water-soluble 2-thio sacc

80 In contrast, we developed a one-step design strategy using phylogenetic analysis and

81 s the potential to be used for point-of-care one-step detection of norovirus in clinical samples.

82 e demonstrate the multiplexed, quantitative, one-step detection of various macromolecules in the low

83 ts sensitivity, specificity, and utility for one-step diagnosis of V-HCV infection using 365 serum sp

84 ntigen tests provided potential for possible one-step diagnosis.

85 Here, the one-step direct synthesis of 2D Mo2 C-on-graphene film b

86 ed hollow fiber membrane was developed via a one-step dry-jet wet spinning.

87 ous GaN layers that are obtained by a facile one-step electrochemical etching method without any extr

88 /rGO nanocomposites simultaneously formed by one-step electrochemical reduction have promising biomed

89 re coated onto a screen-printed electrode by one-step electrodeposition and used to conjugate the HA

90 tube/carbon paste electrode (GNPs /MWCPE) by one-step electrodeposition under controlled potential, t

91 ticles in the o-phenylenediamine network via one-step electropolymerization on the surface of the mod

92 ng pyrrole and carboxylated pyrrole that was one-step electropolymerized jointly with cTnT by cyclic

93 One step emphasizes shared common identity and promotes

94 end maturation in Escherichia coli employs a one-step endonucleolytic pathway that does not involve a

95 g peptide (GBP) on their surfaces for simple one step enrichment and surface functionalization.

96 an alternative approach for an automated and one-step enzyme-linked immunosorbent assay (ELISA).

97 All derivatives were obtained by simple one-step esterification of oleanolic acid prior to pharm

98 n-switch was conventionally believed to be a one-step event in the bulk counterpart.

99 The simplified one-step extraction without saponification significantly

100 We report a microfluidic approach for one-step fabrication of polyelectrolyte microcapsules in

101 Here we describe an approach to the one-step fabrication of three- and four-phase complex em

102 phene artificial throat has the advantage of one-step fabrication, high efficiency, excellent flexibi

103 Herein, we report a one-step facile synthesis of a novel precious-metal-free

104 he activation of both the MH and XH bonds in one step, facilitating proton transfer and preparing the

105 A versatile platform for the one-step fluorescence detection of both monovalent and m

106 A one step formal [3+2]-annulation protocol for the synthe

107 This novel approach enables the one-step formation of CsPbI3/PEDOT composite, which coul

108 A photo-redox-catalyzed procedure for the one-step formation of sultones from alpha,omega-alkenols

109 ose that the R213I mutation in RF2 brings us one step forward toward engineering an omnipotent RF in

110 erized with lauryl methacrylate via a simple one-step free radical polymerization to produce a "self-

111 l- and octatetraynyl-substituted pyrroles in one step from 1-halopolyyne precursors is reported.

112 prepared under ambient conditions in one pot/one step from alkynes.

113 ors of P-stereogenic ligands was obtained in one step from commercial chlorophosphines.

114 catalysis is used to synthesize indolines in one step from iodoacetanilides and alkenes.

115 describe a chiral Bronsted acid prepared in one step from naturally occurring (-)-menthol and readil

116 amilies of high molecular weight polymers in one step from readily available monomers.

117 il and Cinnarizine, have been synthesized in one step from the commercial amines under this Mitsunobu

118 salt and its [(18)F] radiolabeling within a one-step, fully automated and cGMP compliant radiosynthe

119 novel electron acceptor was synthesized from one-step functionalization of the readily available indi

120 In this work, we go one step further and search for links-entangled structur

121 In this paper, we go one step further in the understanding of the laser desor

122 Stomatopod crustaceans appear to have gone one step further in this arms race and have evolved a se

123 This work advances one step further toward understanding the mechanism of f

124 A one-step, gas-phase photothermocatalytic process for the

125 ting by zygote injections can facilitate the one-step generation of non-mosaic livestock animals with

126 The choice of protecting groups permitted a one-step global deprotection (Na/NH3(l)).

127 ive glycosylation reactions, and enabled the one-step global deprotection of the completely assembled

128 ford 22 in excellent diastereoselectivity, a one-step gold-catalyzed propargylic acetate rearrangemen

129 ody on the catalyst surface follows a simple one-step grafting from approach through radical polymeri

130 onofluoroboronates that can be prepared in a one step, gram-scale fashion from readily accessible KAT

131 One-step green microwave synthetic approach was develope

132 o have immense significance in the design of one-step, green bioreactors for stereoselective drug met

133 We demonstrated its utility with one-step HHH purification of a wide range of traditional

134 The application of the protocol in a simple one-step high-yield route to pharmaceutically important

135 take advantage of this discovery to perform one-step homogeneous assays of many non-glucose targets

136 We report on one-step hybridization of silver, gold and palladium nan

137 One step hydrothermal process was used for uniform decor

138 ere prepared by an economic and eco-friendly one-step hydrothermal method using a series of Brassicac

139 al green precursors i.e. carrot juice by the one-step hydrothermal process.

140 fluorescent C-Dots were synthesized using a one-step hydrothermal reaction, with citric acid serving

141 al blue Ti(3+)/TiO2 crystals were grown by a one-step hydrothermal reaction.

142 innovative strategy, which follows a simple one-step immobilization procedure, shows exceptional res

143 Here we demonstrate a novel homogeneous one-step immunoassay, utilizing a pair of recombinant an

144 ent developments in synthetic biology enable one-step implementation of entire metabolic pathways in

145 ways achieves an improvement compared to the one-step imputation by the state-of-the-art methods Beag

146 e to impute more accurately than the classic one-step imputation.

147 ganotrifluoroborates can be (18)F-labeled in one step in aqueous conditions via (18)F-(19)F isotope e

148 artial credit can be given to achievement of one step in isolation of all steps in the continuum.

149 One step in many pipelines is PCR duplicate removal, whe

150 One step in this assembly in budding yeast is the associ

151 ignal amplification process can be completed one-step in this system.

152 products with acetyl and carboxyl groups in one step, in good yields, and with short reaction times.

153 on of caspase-4/5 as the key determinants of one-step inflammasome activation in human monocytes prov

154 ation of the intermediates, whereby at least one step is catalyzed by an enzyme.

155 The IA procedure was based on the one-step kinetics-based sandwich IA employing a minimum

156 Here, we report a one-step label-free electrochemical sensor comprising a

157 pid protein bioconjugation method based on a one-step ligand exchange using the DNAs as the linker.

158 lity of DNA as a scaffolding material with a one-step lithographic process, we demonstrate the patter

159 , together with other useful chemicals, in a one-step low-pressure process.

160 Transposon Analysis in Yeast (SATAY) allows one-step mapping of all genetic loci in which transposon

161 w this reaction can change from a concerted, one-step mechanism in gas phase to a stepwise pathway, i

162 Here, a simple, one-step mechano-chemical process to exfoliate and funct

163 One-step meta-analysis of individual participant data us

164 A simple one step method for the alcohol oxidases (AOx) protein m

165 A novel one-step method for the synthesis of bright, multicolor

166 Here we report a simple, inexpensive, one-step method that allows for the rapid and efficient

167 Here we describe an IP-free one-step method that enables stable genome integration i

168 We report a facile one-step method to fabricate planar heterojunction perov

169 ubtype B gene (B41), together with a simple, one-step method to purify native-like trimers by affinit

170 emonstrated to provide an easily up-scalable one-step method toward the deposition of a new class of

171 is of BMP and PG species was developed after one-step methylation of lipid extracts in combination wi

172 s the main subject of this paper, features a one-step Michael addition of t-butyl 2-((diphenylmethyle

173 th amine moieties were synthesized using the one-step microwave pyrolysis of citric acid in the prese

174 Here, we show that homogeneous, one step (mix-and-read) TFA methods can be extended to t

175 als for chemical processes, and we present a one-step, multigram scale-up route for highly soluble 's

176 ed on bacterial genomic data, we developed a one-step multiplex PCR assay to identify Salmonella and

177 his study, we have developed and validated a one-step multiplex reverse transcriptase PCR (RT-PCR) to

178 cleation pathway is favoured over the direct one-step nucleation because the energy of the solid/liqu

179 peptides that do not attract, the classical one-step nucleation mechanism is possible but only at no

180 The polymeric ligands are built using a one-step nucleophilic addition reaction between poly(iso

181 sobutylene-alt-maleic anhydride) chain via a one-step nucleophilic addition reaction.

182 most cases, the formation of the C-O bond is one step of a domino reaction leading also to a C-C or C

183 e can obtain the desired Hamiltonian in only one step of applying the BCH formula.

184 tCRISPRi to target a new gene requires only one-step of oligo recombineering.

185 N-sulfinyltritylamine (TrNSO), available in one step on 10 gram scale, as a linchpin.

186 oxidant-induced reaction pathways, either in one step or in a stepwise fashion, to bisquinoline-annul

187 eous FAU-type zeolite, HOU-3, prepared via a one-step organic-free synthesis route.

188 of our Bayesian model is that it can produce one-step output of each locus being either equal-, hypo-

189 w set of primers and probes was designed for one-step pan-IAV reverse-transcription fluorescence reso

190 The detection limit of one-step pan-IAV RT FRET-PCR was 10 copies of the matrix

191 Human monocytes exhibit an unconventional one-step pathway of inflammasome activation in response

192 This one-step pathway requires Syk activity and Ca(2+) flux i

193 We report a one-step polymer-free approach to patterning graphene us

194 The polymer NPs can be synthesized in a one-step polymerization reaction using commercially avai

195 Hyperbranched polymers are obtained through one-step polymerization reactions and exhibit properties

196 tion of the device, which could be used as a one-step, portable, disposable, low-cost, simple, instru

197 aggregation of sub-micron particles, using a one-step procedure followed by a fast, particle-by-parti

198 ntrolled polymers were made via a direct and one-step procedure for CuAAC activation.

199 n condition resulted in the development of a one-step procedure for the synthesis of N-acetyl,N'-tosy

200 This one-step procedure involves treatment of anilines with N

201 We have developed a one-step procedure to a variety of chiral lipophilic and

202 te two interpenetrating networks in a simple one-step procedure.

203 nol, and formaldehyde) were synthesized in a one-step process from CO2 and CH4 at room temperature (3

204 is material was fabricated using a scalable, one-step process involving the pyrolysis of a polyanilin

205 complete release of the iron-based core in a one-step process revealing a cross-linked HS-ApoFt with

206 thylsiloxane) elastomers are fabricated by a one-step process via crosslinking bottlebrush polymers.

207 ce sequentially through a typical two-stage, one-step process.

208 or cells and subsequently their progeny in a one-step process.

209 ion of promoters and genes, which allows for one-step production of DNA constructs.

210 A one-step protocol has been developed for the enantiosele

211 Subsequently, a simple one-step protocol was established for the purification a

212 an aptamer and a small molecule in a facile one-step protocol without the use of a complex assay or

213 transfer agent (1) is easily prepared via a one-step protocol.

214 ction is another practical advantage of this one-step protocol.

215 We developed a multiplex one-step quantitative reverse transcription-PCR (qRT-PCR

216 separation efficiency of Nd/Sm system and a one-step quantitative separation of Nd/Dy with the aid o

217 The new one-step QuEChERS strategy was compared to other methodo

218 A one-step QuEChERS-based approach to extraction and clean

219 terial, and the enzyme was immobilized via a one step rapid and simple procedure that does not requir

220 The polymers are synthesized through one-step rapid polycondensation of two nontoxic building

221 ll, the Alere i strep A test could provide a one-step, rapid, point-of-care testing method for GAS ph

222 nce peak, is easily synthesized via a simple one-step reaction and is formulated in water with high s

223 lts were obtained in quantitative yield in a one-step reaction at ambient temperature from the commer

224 on of the reaction course indicate a virtual one-step reaction between the NHC and the silanorbornadi

225 They can be additionally modified in a one-step reaction with functional groups for covalent la

226 (Co-Cryp) was successfully synthesized by a one-step reaction.

227 afion) showed a voltammetric signal due to a one-step redox reaction of the surface-confined myoglobi

228 This method achieves one-step, redox-neutral synthesis of catechols with dive

229 primary C-6 benzyloxy group, LiAlH4-mediated one-step reduction of acetate groups, and reductive ring

230 anoparticles (Tyr-Au NPs) were fabricated by one-step reduction of Au(3+) ion using Tyr as a reducing

231 Here, we report a one-step, regioselective, metal-free (18)F-labeling meth

232 One-step reverse transcriptase PCR (RT-PCR) was performe

233 and the use of different enzyme mixtures in one-step reverse-transcription loop-mediated amplificati

234 nal worms and rods directly in water using a one-step reversible addition-fragmentation chain transfe

235 cell lysates amenable to direct analysis by one-step RT-qPCR.

236 d graphene oxide microspheres synthesized by one-step salt-assisted spray drying using a mixed soluti

237 Here we report a simple one-step scalable approach, where MoOx/MoS2 core-shell n

238 iodic table, their compounds, or alloys by a one-step, scalable, low-cost, and eco-friendly process.

239 xceptional efficiency of this method, termed one-step selective exoenzymatic labeling, or SEEL, great

240 cone symmetry restricted to be two-fold, the one-step sharp magnetization reversal is realized and gi

241 This one-step "signal on" biosensor takes 20min for the sensi

242 ments as receptor proteins were utilised for one step site-directed immobilisation on the surface of

243 asslands were simultaneously extracted using one-step solid-liquid phase.

244 structures was carried out through a facile, one-step, solid-state pyrolysis process in an inert atmo

245 st pinhole-free perovskite films by a simple one-step solution coating with only a few minutes anneal

246 A facile one-step solution reaction route for growth of novel MoS

247 hesized on Au-coated substrates using simple one step sonochemical approach.

248 ntrast agent (perfluoropentane, PFP) using a one-step sonoporation method to create ELTSLs and ENTSLs

249 The one-step spin-coating process of perovskites is investig

250 ality of dendrimers, since the heteroleptic, one-step, spontaneous self-assembly process facilitates

251 articles was coated with components of a DNA one-step strand displacement (OSD) reaction to release t

252 old-mediated strand exchange reaction termed one-step strand displacement (OSD).

253 This one-step strategy provides for both robust, relatively s

254 Compared to the one-step strip assay, the proposed chip is capable of pe

255 Thus, oligolysine-PEG is a one-step, structure-independent approach that provides l

256 tive polymer nanocomposite was obtained by a one-step synthesis approach based on room temperature di

257 We report a one-step synthesis for Fmoc-fluorosulfated tyrosine.

258 oluble in organic media are synthesized in a one-step synthesis from a single-source precursor (an am

259 The one-step synthesis method of nitrogen doped microporous

260 A palladium-catalyzed one-step synthesis of (hetero)aryl alkyl sulfones from (

261 We designed and developed a one-step synthesis of 5-amino-4-carboxamidothiazoles 1 b

262 A one-step synthesis of a nanographene propeller with a D3

263 This methodology was adapted for the one-step synthesis of a series of clinically active topo

264 A novel one-step synthesis of anthraquinones and chloro anthraqu

265 A general asymmetric route for the one-step synthesis of chiral beta-branched amides is rep

266 A one-step synthesis of Fmoc-protected aryl/heteroaryl-sub

267 This study reports the convenient, low cost, one-step synthesis of labelled analogues of six volatile

268 a pneumoniae was overexpressed to access the one-step synthesis of oxaloacetate directly from phospho

269 We report the one-step synthesis of poly(aryl ether sulfone)s (PSUs) f

270 xide-mediated polymerization strategy allows one-step synthesis of recyclable crosslinked polymeric m

271 In this paper, we report a simple one-step synthesis of well-dispersed amorphous cobalt hy

272 This study reports a room-temperature and one-step synthesis technique that leads to large-scale a

273 easy removal of the N-protective group, and one-step synthesis under "open-flask" are advantages of

274 This practical and scalable method provides one-step synthetic access to primary anilines and phenol

275 strain-free heterocyclic precursors using a one-step synthetic procedure, involving multiple nickel-

276 a wide range from 20 to 1000 nm followed by one-step thermal activation.

277 These nanoparticles are produced via a one-step thermal alloying process.

278 ead to an increased variability of gait from one step to another, raising the likelihood of falls.

279 -H2O, convert simple achiral barbiturates in one step to hemiaminal- or enamine-containing tricyclic

280 This method adds just one step to the classical peptide mapping workflow.

281 eicosanoic acids caused a transition from a one-step to two-step process.

282 ing the age to start screening are imminent, one step toward integrating screening and vaccination.

283 One step toward the understanding of the role of transth

284 r HTLV-1 cell-mediated infection in a simple one-step transfection/infection assay.

285 wo models for this process: "gobbling," i.e. one-step transfer of all HDL-CE to the cell and "nibblin

286 Here we report, a one-step transformation of Chlamydomonas reinhardtii by

287 is exemplified with multiple highly diverse one-step transformations to synthetically useful buildin

288 ad range of molecular scaffolds upon further one-step transformations, demonstrating the utility of y

289 One-step treatment with PI 4-kinase IIIbeta (PI4Kbeta) y

290 of the parent halides, a new methodology for one-step trimethylstannylation was developed and optimiz

291 This one-step 'turn on' homogenous assay in a ready-to-use mi

292 V) on mineral surfaces is often considered a one-step two-electron process.

293 ned technician to operate, and only requires one-step user involvement.

294 -purin-2-(3H)-ones 25-26 were synthesized in one step using formic acid, urea, guanidine carbonate, a

295 Here, we demonstrate dilution-free, one-step UV-vis spectroscopic analysis of high concentra

296 propanol substrates are readily available in one step via a Kulinkovich reaction of the corresponding

297 nanorods were synthesized through a facile, one-step, wet-chemical method by the use of just FeF33H2

298 -value molecules from feedstock chemicals in one step while consuming only photons.

299 ve-cell membrane proteins can be achieved in one step without any pre-treatment.

300 This study proposed a one-step wood modification method by combining the depos