ライフサイエンスコーパス: ongoing

1 prevent cardiometabolic conditions are still ongoing.

2 ting that EGT in Paulinella chromatophora is ongoing.

3 ist antibodies, urelumab and utomilumab, are ongoing.

4 to augment response rates and durability are ongoing.

5 (data cutoff), 74 (83%) of 89 responses were ongoing.

6 elodysplastic syndromes; further studies are ongoing.

7 monotherapies in malignant mesothelioma are ongoing.

8 complete, although an extension (Part 2) is ongoing.

9 confirmatory phase III part of the study is ongoing.

10 Recruitment has ended, but follow-up is ongoing.

11 r further development and phase 3 trials are ongoing.

12 ase II studies with biomarker evaluation are ongoing.

13 ely that some dysfunction is also due to the ongoing absence of FMRP.

14 Ongoing access to healthcare, psychosocial support, and

15 Simulations indicated an ongoing acidity loading at the site, and the depletion o

16 monstrate that nigrostriatal dopamine biases ongoing action selection.

17 e emerging as critical components underlying ongoing activation in HIV infection.

18 l as spiking patterns during both periods of ongoing activity and during sensory stimulation, reflect

19 s made of transposable elements (TEs), whose ongoing activity continues to impact our genome.

20 y deviated from scale-invariance compared to ongoing activity.

21 cortex integrate the sensory inputs with the ongoing activity.

22 uce a differential immunologic profile, upon ongoing AdMSC suppressive activity, promoting: (i) early

23 tudy began in November 2013 and is currently ongoing.Amyloid was elevated in 26% (n = 33) of particip

24 l-controlled multicenter clinical trials are ongoing and data are awaited.

25 rt study with the second dose-expansion part ongoing and enrolling patients as of July 8, 2017, in Ja

26 pathogenesis of these tumors and highlights ongoing and future research.

27 We conclude that the ongoing and past methane emission episodes at the invest

28 In time, it is hoped that data from ongoing and planned clinical trials will allow us to rou

29 coping strategy due to the rate and scale of ongoing and potential future change.

30 In the present study, we investigated how ongoing and visually driven activity in magnocellular (M

31 an between 1989 and 2011, with all but three ongoing, and each had 2-16 assessment waves (median = 3)

32 saline over a 12-week course, in addition to ongoing antidepressant.

33 These efforts are ongoing as new projects are developed and the network ex

34 Debate is ongoing as to whether the procedure is equivalent to ope

35 (PROACTOR) Task Force was created to inform ongoing ASTS organ access efforts.

36 4 months), a patient with urothelial cancer (ongoing at >/= 19 months), and a patient with osteosarco

37 vical cancer who received 2.7 x 10(9) cells (ongoing at >/= 29 months).

38 al) sinusoidal obstruction syndrome that was ongoing at the time of death due to septic shock.

39 The other 5 experienced ongoing autoimmune problems, including thyroiditis (3),

40 of HMB should be assessed and treated on an ongoing basis.

41 nformation being shared previously and on an ongoing basis; having asked all their questions; therape

42 17) show that correlating these results with ongoing behavior and plasma osmolality points to the exi

43 ironment, and integrate these functions with ongoing behavior.

44 he EEG and interruption of consciousness and ongoing behavior.

45 fication of candidates for intervention, but ongoing bladder dysfunction in patients after valve abla

46 Because of the ongoing boom in dam building, in particular in emerging

47 Ongoing bowel symptoms were present in 16.3% of patients

48 ng long-range dependence or "memory" in slow ongoing brain activity.

49 modulate the temporal width of LRD in slower ongoing brain activity.

50 es, cause brain tissue hypoxia, a measure of ongoing brain injury.

51 structures at both 6 months and 12 months of ongoing brain stimulation.

52 is a need for new interventions against the ongoing burden of vector-borne diseases such as malaria

53 Palestinian population, a situation in which ongoing-but fragile and limited-health cooperation and t

54 The ongoing Caribbean outbreak is of concern due to the pote

55 An ongoing challenge is the identification of biomarkers th

56 an cancers into therapeutic strategies is an ongoing challenge.

57 , selective C-H functionalization is a major ongoing challenge.

58 g the current state of knowledge, we outline ongoing challenges in experimental design that remain to

59 rize these advances and offer perspective on ongoing challenges.

60 limate identifies obstacles to communicating ongoing changes in climate to the public and how these c

61 Ongoing changes in global climate are altering ecologica

62 activated DDR during mitosis, which leads to ongoing chromosome segregation errors.

63 lasticity will likely fail to compensate for ongoing climate change when such change results in novel

64 n climate; (iii) our forecasts indicate that ongoing climate change will likely shift these ecotypes

65 climatic selection vs. plastic responses to ongoing climate change) and (ii) to explore which climat

66 In the context of ongoing climatic warming, certain landscapes could be ne

67 Although many ongoing clinical challenges remain, this review will als

68 arch for imaging coronary artery plaque, and ongoing clinical studies are testing whether there is an

69 w is to provide an overview of completed and ongoing clinical studies performed using microneedle-bas

70 Ongoing clinical trials are helping to further elucidate

71 Relevant to ongoing clinical trials in breast cancer, we demonstrate

72 Ongoing clinical trials in patients with mIDH advanced h

73 In this Review, we detail the ongoing clinical trials of Treg therapy in liver and kid

74 n through vaccination motivates imminent and ongoing clinical trials of viable candidates to realize

75 et sources for randomized controlled trials, ongoing clinical trials, and unpublished studies up to A

76 rvention communities in the SEARCH Study, an ongoing cluster randomized trial.

77 ndicators will also evolve over time through ongoing collaboration with experts and a range of stakeh

78 ine has made 14 recommendations that require ongoing commitments to eradication of infectious disease

79 tream circuits while still maintaining other ongoing communication with these targets.

80 ung children provide a critical indicator of ongoing community transmission of M. tuberculosis.

81 There are also ongoing concerns about patient care for older people in

82 her refinement, and mark the beginning of an ongoing consultation process-from November, 2016 to earl

83 s generated by the MFC and synchronized with ongoing consummatory actions.

84 black carbon has been identified as a major, ongoing contributor to anthropogenic climate change, thu

85 sights into the current clinical management, ongoing controversies, and future needs in oesophageal c

86 Here we review the current data and the ongoing controversies.

87 nation of medical knowledge and discovery as ongoing conversations between professionals and their ex

88 higher incidences of phase-locked firing to ongoing cortical oscillations, and SPN ensembles showed

89 ed out-of-pocket costs (direct costs) and/or ongoing daily expenses while losing income (indirect cos

90 This study is ongoing; data for this interim analysis were collected p

91 There is an ongoing debate on the contribution of the neuronal gluta

92 Finally, we present the ongoing debate on the possibility of linking polyamorphi

93 ic athletes in Olympic events are matters of ongoing debate.

94 Most of the ongoing debates about Kraepelin's nosology have roots in

95 Ongoing debates on optimal cell population(s) for treatm

96 nput with that from the recent past to guide ongoing decision making.

97 diversity, and highlights the potential for ongoing declines in vertebrate seed dispersers to profou

98 There is still an ongoing demand for a simple broad-spectrum molecular dia

99 etection in many situations, and there is an ongoing desire for them to perform at the highest level.

100 nt over time, their replication implies that ongoing destruction likewise occurs.

101 The ongoing deterioration of wetland ecosystems in many shal

102 Continuous ongoing development of dense integrated circuits require

103 res of single-antigen vaccines have prompted ongoing development of multicomponent vaccines to target

104 This supports ongoing development of NaF PET/CT-based imaging biomarke

105 as immature OSNs exhibiting the hallmarks of ongoing differentiation including GAP43, PGP9.5, but the

106 to advance rapidly, along with prospects for ongoing discovery.

107 der parity of invited speakers may allow the ongoing discussions to be informed.

108 nt gene duplication event resulting from the ongoing diversification of sHsps in the Volvocales.

109 DBAN does not hinder ongoing DNA replication, but specifically blocks the ser

110 h which RPA couples nucleosome assembly with ongoing DNA replication.

111 some events seem readily attributable to an ongoing drought while others do not.

112 Genome doubling and ongoing dynamic chromosomal instability were associated

113 hat MSC-Exo greatly reduced the intensity of ongoing EAU as their parent cells by reducing the infilt

114 There is a significant ongoing effort in realizing quantum annealing with diffe

115 Ongoing effort is warranted to recognize and mitigate po

116 At present, there is an ongoing effort to develop methods to effectively quantif

117 The ongoing efforts dedicated to the replacement of a lab-ba

118 ive measures including maternal vaccines are ongoing efforts designed to reduce the burden of neonata

119 This case contributes to the ongoing efforts of simultaneous BRAF/MEK inhibition as a

120 These data support ongoing efforts to centralize care for patients undergoi

121 their suspected impact on hematopoiesis; (4) ongoing efforts to develop new models to study niche-leu

122 life cycle and a key intervention target of ongoing efforts to eradicate malaria.

123 The pheromone will also be a crucial tool in ongoing efforts to eradicate the beetle from regions of

124 Our findings suggest that the ongoing efforts to improve crop photosynthesis by integr

125 The findings will help to guide ongoing efforts to understand the etiology of neurodevel

126 Despite ongoing efforts, an efficient tool for accurate estimati

127 ability to monitor metabolic alterations and ongoing electrical activity, thus contributing to a bett

128 ndependent events, so that only data from an ongoing episode are considered pertinent to evaluating e

129 ncoding sequences, have been critical in the ongoing evolution of MYXV virulence.

130 scalable manner, essential to the notion of ongoing evolution.

131 ionary trajectories, including long-term and ongoing evolutionary decline.

132 From the completed first stage and ongoing expansion stage of this trial, a total of 21 con

133 tigen, led to myelin-specific suppression of ongoing experimental allergic encephalomyelitis (an MS a

134 Ongoing exposures to even relatively low drinking water

135 Brain-dead patients with ongoing extracorporeal membrane oxygenation have more se

136 single-pulse TMS should also quickly disrupt ongoing eye motion.

137 udy using baseline (2013-2015) data from the ongoing Falls in Glaucoma Study (FIGS).

138 rized by proteins involved in wound healing, ongoing fibrosis, and inflammation.

139 t known how that depends on the stage of the ongoing follicular T cell and GC B cell response.

140 2005, and December 9, 2008, 215 consented to ongoing follow-up through at least 7 years postrandomiza

141 Further study of SANS is ongoing for consideration of future manned missions to s

142 nce in 5 of 6 participants and has exhibited ongoing function for up to 24 months.

143 wing nerve injury is associated with altered ongoing functioning of the brainstem descending modulati

144 secondary lymphoid organs, they may join the ongoing GC response.

145 dly evolving field of genomic investigation, ongoing genetic research offers unique contributions to

146 ion, and likely tumor evolution, rather than ongoing genomic instability.

147 f contemporaneous ocean-forced change and of ongoing glacier response to an earlier perturbation in d

148 reeding and to deliver real world impact for ongoing global food security efforts.

149 Forest fragmentation is a ubiquitous, ongoing global phenomenon with profound impacts on the g

150 of tuberculosis transmission are driving the ongoing global tuberculosis epidemic, and there is a pre

151 Due to ongoing global warming and rising temperatures, it is li

152 nces for the application of these methods in ongoing GWAS meta-analyses and large biobank studies.

153 trial in two districts of western Kenya with ongoing HBCT.

154 cortical stimulation leads to a reduction in ongoing hippocampal-evoked MSNs responses through the co

155 llance period during which patients received ongoing HIV medical care.

156 he stem cell response to immune therapies in ongoing human clinical studies may help identify and max

157 ors limiting entry of new B cell clones into ongoing immunization-triggered GC responses.

158 (68%) had persistent medical issues, mainly ongoing immunoglobulin replacement (14; 45%), cutaneous

159 t limiting transmission of these viruses are ongoing in multiple countries, yet there is a dearth of

160 ve and modifiable disease processes might be ongoing in patients with mild to moderate, persistent as

161 Accrual is ongoing in some disease cohorts.

162 e human applicability of ASOs, we anticipate ongoing in vivo research and clinical trial development

163 There is a growing consensus that the ongoing increase in atmospheric CO2 level will lead to a

164 a better understanding of plant responses to ongoing increases in global temperature and drought seve

165 tional myocardium may persist, in part, from ongoing inflammation and poor extracellular matrix remod

166 Baltic Sea campaigns, during the preinflow, ongoing inflow, and subsiding inflow of water, respectiv

167 ISGs in their sputum cells that may reflect ongoing innate immune activation.

168 The goal of the Banff process is ongoing integration of advances in histologic, serologic

169 As part of our ongoing interest in main group species that support the

170 incomplete postzygotic isolation could allow ongoing interploid gene flow, especially among higher or

171 Ongoing intratumoral evolution is apparent in molecular

172 plotypes described here, probably indicating ongoing invasion and re-introduction of H. halys.

173 hey may be rationally activated are areas of ongoing investigation.

174 status, presence of clinical instability or ongoing ischemic symptoms, prior reperfusion therapy, ri

175 ed during the west Africa epidemic, identify ongoing knowledge gaps, and suggest priorities for futur

176 twenty-two subjects recruited as part of an ongoing large clinical population study completed a chan

177 Ongoing larger randomized trials will clarify whether mo

178 and surgical procedures and ensure that our ongoing level of treatment aligns with patients' and car

179 Ongoing LMWH and A6 hyperalgesia are reversed by HMWH.

180 capital costs, which suggests an emphasis on ongoing maintenance subsidies rather than upfront capita

181 The patient currently receives ongoing maintenance treatment, consisting of the ingesti

182 is updating process critically depends on an ongoing mapping between the representations and the obje

183 ehavioral profile that may be constrained by ongoing maturation of corticostriatal connectivity.

184 ing better ways to anticipate and manage the ongoing microbial challenge will be critical for achievi

185 s-TnT) serum levels revealed the presence of ongoing minute myocardial injury even in patients with s

186 ctively, these data provide a snapshot of an ongoing molecular arms race between viral suppressors an

187 brosis, before randomization to either CA or ongoing MRC.

188 llaborative HIV Cohort (UK CHIC) Study is an ongoing multicentre cohort study that brings together in

189 In this ongoing, multicentre, open-label, phase 2 trial, we enro

190 propagated perennial crop, to address three ongoing mysteries about plant domestication.

191 on Survey (NHANES; 2005-2010; n = 9,316), an ongoing nationally representative US survey, we used mul

192 concentrations is one of the world's largest ongoing natural disasters.

193 recommendations are based on the literature, ongoing natural history studies, and extensive clinical

194 gaps and the relevance and applicability of ongoing natural range expansions in the context of clima

195 phase 3 study in this patient population is ongoing (NCT02348489) to assess guadecitabine 60 mg/m(2)

196 and research applications, yet its effect on ongoing neural activity in humans is not well establishe

197 that measures cerebral perfusion related to ongoing neural activity.

198 fluences perception and interacts with other ongoing neural activity.

199 In particular, this report details the ongoing neural adaptations that allowed a functional pro

200 tegration/segregation, in which the phase of ongoing neural oscillations determines whether two stimu

201 TSPO binding or expression may indeed mirror ongoing neuroinflammatory processes in some cases, it ma

202 monitor lactate and glucose fluctuations and ongoing neuronal activity with high spatial and temporal

203 nencapsulated meningococcal isolates from an ongoing Nm urethritis outbreak among epidemiologically u

204 s are sufficiently fast that, as a result of ongoing NO x emission reductions, autoxidation is now co

205 ined mechanism that simultaneously restrains ongoing obsolete actions while it facilitates new contex

206 The ongoing OCEAN study enrolled patients treated with ranib

207 We hypothesized that entrainment would align ongoing oscillations and drive them toward the stimulati

208 y entrainment, supporting a critical role of ongoing oscillations in the integration/segregation of i

209 t, providing evidence for a critical role of ongoing oscillations in the temporal organization of per

210 creased risk of neurocognitive events in the ongoing outcome studies and post-marketing surveillance.

211 f nociceptive sensory afferents reduced both ongoing pain and evoked cutaneous hypersensitivity in th

212 Even when ongoing pain is well controlled, patients can suffer bre

213 pain is characterized by moderate to severe ongoing pain that commonly requires the use of opiates.

214 Our study demonstrates that the ongoing paradigm shift, which recognizes that both bioti

215 ears of formal schooling, can counteract the ongoing pathological process.

216 We suggest that this share may increase if ongoing permafrost thaw opens new pathways.

217 We applied our approach to an ongoing phase Ib clinical trial (TATTON) administering A

218 Rates of ongoing pregnancy and live births were higher among wome

219 The primary outcome was ongoing pregnancy within 6 months after randomization.

220 We find evidence of ongoing, primarily male, migration from the steppe to ce

221 he nuclear genome by mitochondrial DNA is an ongoing process in eukaryotes and plays an important rol

222 egion of Mozambique where urbanisation is an ongoing process.

223 An ongoing progressive mobility program in the neurocritica

224 ty, and mortality.The UK Biobank study is an ongoing prospective cohort of >0.5 million UK adults age

225 d the anticipated heterogeneity, favoring an ongoing prospective matched-pair analysis of patients wi

226 age cells with a short half-life and minimal ongoing protein synthesis.

227 on Industrial Emissions (IED), but there is ongoing public concern regarding potential hazards to he

228 IAV reassortment will inform and strengthen ongoing public health efforts to anticipate the emergenc

229 An ongoing question is whether CENH3 evolution is driven by

230 s is triggered in physiological settings are ongoing questions.

231 nsidered standard high-dose chemotherapy and ongoing randomised studies will continue to aim to optim

232 NEMO is an ongoing, randomised, open-label phase 3 study done at 11

233 This ongoing, randomized open-label extension trial (OSLER-1)

234 (<50 years ago) might have been triggered by ongoing rapid warming, as the area is experiencing clima

235 losure on health should continue despite the ongoing recovery of the housing market.

236 ignation of rectal cancer centers to support ongoing regionalization of care.

237 Ongoing research efforts, including the development of p

238 Our findings underscore the need for ongoing research in this area but also increased dissemi

239 In this review, we provide an overview of ongoing research on mAbs and antibody-related theranosti

240 l review identifies key questions related to ongoing research on the oral health-related quality of l

241 lation involved in metastatic virulence, and ongoing research seeks to characterize the extent to whi

242 Despite ongoing research, high glucocorticoid efficacy and wides

243 isease, including one patients with RCC with ongoing response > 3.5 years.

244 estimates for progression-free survival and ongoing response were 82% (95% CI 66-91) and 89% (95% CI

245 nd 19 (34%) of 56 with nonsquamous NSCLC had ongoing responses after 2 years' minimum follow-up.

246 mutant has no growth defect, arguing against ongoing restriction of its own DNA.

247 he adult, indicating that local cues play an ongoing role in shaping microglial diversity.

248 Without the latter, the ongoing scientific efforts and excitement surrounding th

249 The ongoing search for progress and the growing understandin

250 iteria were (1) pediatric seizure onset with ongoing seizure activity in adulthood, (2) intellectual

251 d SOM+ interneurons ultimately help maintain ongoing seizures.

252 otemporal patterns of bill length, suggested ongoing selection for longer bills in the United Kingdom

253 We provide direct evidence of ongoing sensitization of neuronal signaling in the bowel

254 However, the ongoing shortage of suitable organs can limit transplant

255 s over their classical counterparts has been ongoing since the inception of the field.

256 In this ongoing single-centre, two-stage, phase 2, single-arm tr

257 BOLD activity pattern and were confirmed for ongoing slow wave activity by independent component and

258 eening at the GP surgery did not identify an ongoing source of infection.

259 There is an increasing interest in how ongoing spontaneous brain activity and personality provi

260 of ecological and demographic factors to the ongoing spread of the yellow fever outbreak and provide

261 us to ask to what extent neurons encoded the ongoing stimulus stream versus the animal's percept.

262 e required to monitor efficacy and safety of ongoing strategic vitamin D fortification.

263 nt clinical trials, and gives an overview of ongoing studies and trial concepts that will lead to a m

264 Ongoing studies are warranted to better elucidate the pa

265 As ongoing studies further elucidate the regulation and fun

266 ing MS lesions, and suggest the necessity of ongoing studies of the mechanisms underlying subsequent

267 To support planned and ongoing studies where clade C predominates, here we desc

268 This is an ongoing study to develop an eye screening program using

269 gnetic resonance imaging (CMR, as part of an ongoing study), high-sensitivity troponin I, and B-type

270 and we report the primary analysis from this ongoing study.

271 tween January 1, 2013, and May 25, 2016, and ongoing surveillance in targeted publications through Ma

272 ent compliance with standard precautions and ongoing surveillance.

273 nostic imaging is also helpful in evaluating ongoing symptoms in the subacute or chronic setting.

274 Diagnosis is difficult due to the ongoing systemic inflammatory response.

275 Contraindications are limited to ongoing systemic severe pathology, asthma and eye diseas

276 of materials at the nanoscale represents an ongoing technological challenge for a variety of integra

277 pment to modify this congenital infection is ongoing, the unique epidemiology of maternal HCMV infect

278 should be maintained and expanded to provide ongoing therapy for chronic infectious disease, there is

279 ent to expanded cohorts of those subtypes is ongoing to confirm and characterise the activity of pemb

280 Research is ongoing to develop drug therapies to manage osteoarthrit

281 Controlled trials are ongoing to validate these conclusions.

282 utionary pathways of indirect effects favour ongoing trait evolution by promoting slow but continuous

283 different TEFs, as well as for coordinating ongoing transcription with mRNA processing.

284 This confirms the positive effect of the ongoing transition to phase out POSF-based products, alt

285 e factors, describe tools for measurement of ongoing transmission, and highlight knowledge gaps that

286 ) before returning to baseline levels during ongoing treatment (IRR, 1.35; 95% CI, 0.77-2.38).

287 ilpivirine and emtricitabine, as initial and ongoing treatment for HIV-1 infection.

288 or secondary prevention in these patients if ongoing trials of anti-inflammatory therapy prove effect

289 Two ongoing trials will assess the risk and benefit of non-v

290 It concludes with discussion of ongoing trials, new approaches, emerging indications, an

291 (1) multiple symptoms during the day despite ongoing use of asthma medications, (2) FEV1 of less than

292 ains whether this is due to chronic effects, ongoing use, or drug withdrawal.

293 To investigate the question of ongoing viral replication on current ART regimens, we an

294 d highly functional yet appeared ignorant of ongoing viral replication.

295 Our results offer insight into halting the ongoing wave of vertebrate extinctions by revealing the

296 Although mechanistic studies are ongoing, we propose that CuH-catalyzed silylation of uns

297 efforts, in academia and industry alike, are ongoing with the main aim to develop advanced functional

298 a greater extent in cells with low levels of ongoing Wnt signaling, suggesting that cells with low ba

299 Interocular suppression is the focus of ongoing work aimed at understanding and treating amblyop

300 gnificant advances in the past few years and ongoing work is poised to add even more.