ライフサイエンスコーパス: only a single

1 nts were included as a control group and had only a single (111)In-girentuximab injection and scintig

2 We find that RAG1/2 binds only a single 12RSS or 23RSS and reserves the second DNA

3 all predicted secondary structural elements, only a single 15-nt stem-loop showed a strong correlatio

4 n a subset of bacteria and archaea, contains only a single 6-TM domain and functions as a tetramer.

5 s with eczema are deferred from vaccination, only a single, accidentally transmitted case of EV has b

6 onds, the same pulse repeated again produces only a single action potential.

7 th OR and OL are tripartite, the presence of only a single active CI binding site in one of the two o

8 ng triggered by TBF was highly restricted to only a single, active cell.

9 n a variety of organisms, but it can mediate only a single activity at a time within any given cell.

10 For most outcomes, there was at most only a single adequately adjusted study, which usually f

11 e exists demonstrating the same effect after only a single administration.

12 e family history compared with families with only a single affected proband (singleton).

13 strains of the 'deep clade' ecotype contain only a single alginate lyase in a separate 7 kb island.

14 lots were used to evaluate samples for which only a single allele was identified by STR analysis.

15 sease, and current vaccine strategies target only a single alphavirus species.

16 However, apoE4 differs from apoE3 by only a single amino acid at position 112, which is argin

17 on assays, isoallelic strains that varied by only a single amino acid in CovS, and transcriptome anal

18 trated in the previous studies, to targeting only a single amino acid without compromising the intens

19 HLA-B*42:01 and HLA-B*42:02, which differ by only a single amino acid.

20 Only a single antibody (Cosmo Bio Co) detects PHLPP1alph

21 We found that only a single antibody molecule can be bound to each prM

22 and tomato grown in field soil amended with only a single application of biosolids (at an agronomic

23 There is no vaccine and only a single approved drug that provides no benefit for

24 l "primer." Thus, these studies suggest that only a single arabinan chain attached near the middle of

25 in the general population and typically used only a single assessment of diet.

26 an and Chinese ancestries generalized, while only a single association previously discovered in a peo

27 these goals, but because graphene comprises only a single atomic layer, it is strongly influenced by

28 to sensors with uniformly oriented VHH (with only a single azide group).

29 ticularly challenging due to the presence of only a single base mismatch in the middle of the 251 bas

30 allele differs from the wild-type allele at only a single base pair.

31 of the let-7 microRNA family that differ in only a single base position.

32 s in hexane or chloroform self-assemble into only a single bcc superlattice.

33 fly genome encodes three proteins that bear only a single BEN domain ("BEN-solo" factors); namely, I

34 rd-occluded and inward conformations present only a single beta-d-glucose interaction site.

35 nals: The first considers DNA fragments with only a single binding event, whereas the second consider

36 As many DNA-binding proteins have only a single binding site, jumping may be a common mech

37 ue culture, or in vitro; typically addresses only a single biochemical function of a protein; and is

38 Current imaging techniques often detect only a single biochemical process, but, within whole org

39 cost manufacturing, but they tend to measure only a single biomarker and provide no information about

40 ase over time; and IM was diagnosed based on only a single biopsy in 89% of patients.

41 lated DNA is demonstrated in the presence of only a single bound protein, thereby giving a resolution

42 were determined in the same experiment using only a single bulk concentration of SBN.

43 ery strongly suggests that the possession of only a single calcareous shell plate and the presence of

44 In our four test cases, only a single candidate single nucleotide polymorphism (

45 ions on other known kinesins, which can bind only a single "canonical" site per tubulin dimer.

46 etric reactions and the most popular install only a single carbon rather than uniting larger fragment

47 lio is now largely eradicated in India, with only a single case in 2011, greater transparency about c

48 By contrast, to date, only a single case of naturally acquired P cynomolgi has

49 ed conditions in clinical medicine, there is only a single case report of a patient with MS and HIV t

50 ual specificity phosphatase that consists of only a single catalytic domain.

51 threshold concentration, BMP4 gives rise to only a single cell fate, contrary to its role as a morph

52 labeling of select interneurons--frequently only a single cell in a large region.

53 em cell-derived cells because of the loss of only a single cell type-the insulin-producing beta-cell.

54 allenged multiple times by the same route or only a single challenge is performed.

55 e in a simulated world and are supplied with only a single channel of communication.

56 us, however, on maternal effects that affect only a single character, whereas the evolution of matern

57 ibit up-regulation of two products even when only a single chemical reaction is addressed catalytical

58 Only a single chimpanzee in control groups, who had not

59 Whereas in a subset of hemispheres only a single cingulate sulcus (cgs) is present, a major

60 Most previous studies have investigated only a single clotting protein and lipid composition and

61 ne in rodents has eight non-coding exons and only a single coding exon (IX).

62 hic images can be realized in real time with only a single coding metasurface.

63 Only a single colony was recovered from 1 of 60 C57BL/6

64 lors of QDs, multiplexing was achieved using only a single color of QD.

65 V variants revealed that their genomes share only a single common difference from that of CpGV-M, whi

66 d theory show that the neutral bisketene has only a single conformation where the two ketene moieties

67 ecially at wide scattering angles, even when only a single conformational state is significantly popu

68 ith a large stabilization energy difference, only a single conformer was found (BEA, LTA and MFI).

69 ese phenotypes were exacerbated in mice with only a single copy of p300 or CBP expressed in islets.

70 utations that improve virus replication with only a single copy of rhtrs1 to evolve, we passaged rhtr

71 sage, we isolated two viruses that contained only a single copy of rhtrs1 yet replicated as well as t

72 Because cohesin contains only a single copy of Smc3p or Mcd1p, these examples of

73 ely on nonhomologous end joining (NHEJ) when only a single copy of the genome is available and mainta

74 oach could detect the BCR-ABL biomarker when only a single copy was present, although multiple screen

75 sequence in the critical region, identifying only a single cosegregating, novel, nonsynonymous mutati

76 Twenty-three patients received only a single course of HDCT because of progressive dise

77 able fluorescent states, as long as there is only a single dark state.

78 nt compositions, on the same Si wafer, using only a single deposition process and a single anneal pro

79 hly heritable, recent studies have localized only a single depression-related locus reaching genome-w

80 ated from a different direction, even though only a single digital projector was used for illuminatio

81 ather and generate clinical data, a focus on only a single disease or treatment, and high development

82 mediate partially reduced species containing only a single disulfide bond were also generated, from w

83 As AAG has only a single DNA binding site, this argues against the

84 ndependence would be achieved routinely with only a single donor.

85 r compact two-electron spin qubits requiring only a single dot and no additional magnetic field gradi

86 Standard methodologies assume only a single drug is used, it acts only in its unconver

87 sequential imaging of multiple targets using only a single dye and a single laser source.

88 the uncoupled cells exhibit either no EAD or only a single EAD, when these cells are coupled to form

89 nding orbital of the radical cation contains only a single electron, giving rise to an elongated C-C

90 oupling of two fluorophores, our design uses only a single emitter, which simplifies ratiometric sens

91 e distal and lingual cusps; this resulted in only a single enlarged cusp in the basin-like heel (talo

92 payloads, and that they are targeted against only a single epitope, which can reduce their selectivit

93 functions as an internal standard requiring only a single excitation wavelength, and is much reduced

94 Some forms of associative learning require only a single experience to create a lasting memory [1,

95 isorders, making it unlikely that modulating only a single factor will provide effective treatment.

96 known to be derived from aerobic organisms, only a single family of polyketides has been identified

97 nup graphene nanoflakes can be fabricated by only a single femtosecond laser pulse, which is efficien

98 al recessive condition described thus far in only a single First Nations population and causes intrau

99 Using only a single fitting parameter that accounts for experi

100 normative view that the motor system selects only a single, flexible motor plan, optimized for uncert

101 binding state was probed simultaneously with only a single fluorescent label.

102 unresolved dark states, as long as there is only a single fluorescent state, or if there are differe

103 dict where motifs are likely to appear using only a single-force parameter and uncover the localizati

104 alues are observed in offshore environments, only a single formation, evidently the shallowest, shows

105 mental data from Salmonella typhimurium with only a single free parameter.

106 brane vesicles, a variant of CTxB containing only a single functional GM1 binding site exhibits signi

107 of the actin nucleator Cobl, despite having only a single G-actin-binding Wiskott-Aldrich syndrome p

108 We detect a near-infrared emission line from only a single galaxy, confirming that some process is ma

109 or revertant viruses when the expression of only a single gC was allowed, indicating that all three

110 apid melt growth technique that comprises of only a single Ge growth step and a single anneal step.

111 Only a single gene encoding a homologue of a plasma memb

112 e chloroplast genome of land plants contains only a single gene for a splicing factor, Maturase K (Ma

113 In five loci, only a single gene was involved: FURIN, TSNARE1, CNTN4,

114 Only a single gene, TREML4, was upregulated in CAC cases

115 Indices producing only a single global statistic (7 of the 8 indices) are

116 iocins across the outer membrane, containing only a single globular ferredoxin domain connected to it

117 tions exclusively as a monomer and possesses only a single glucose binding site.

118 lso remarkable in that they are derived from only a single heavy atom change in the structure.

119 charides in length, are capable of accepting only a single heavy chain (HC) from inter-alpha-inhibito

120 Of six probands with only a single heterozygous mutation in TYR, all were fou

121 evel of reported missing heritability, where only a single heterozygous mutation is found in TYR.

122 fected Nicotiana benthamiana plants revealed only a single highly expressed ORF in this region, desig

123 d periodic acid-Schiff staining, even though only a single histologic section for each PEC marker was

124 efficiently induced antibody responses after only a single immunization.

125 Most basic and translational studies utilize only a single inbred mouse strain.

126 The key study limitation was that only a single infant sample was collected to minimize ve

127 When a cell was infected by only a single infectious particle, variation in the kine

128 neously activates at least two NLRs, whereas only a single inflammasome complex is formed in a macrop

129 Current models will need to change with only a single infusion.

130 died in "well-controlled" environments where only a single input is varied, potentially missing impor

131 tion through interferometric measurements of only a single ion in the chain.

132 o achieve silencing are inefficient, pumping only a single ion per photon across the cell membrane ra

133 hand, only 9 of 39 nondiabetic children with only a single islet autoantibody (GADA only) by radioass

134 r dendrites ensures self-avoidance even when only a single isoform is expressed.

135 1,2-alternate derivatives were formed, while only a single isomer of monoalkylated partial cone and 1

136 tical cohort of 10,000 patients who received only a single kidney transplant and terminated when all

137 at vanishes in the ultra-quantum limit, when only a single Landau level is occupied.

138 ering reduces when the pores can accommodate only a single layer of ions.

139 facile production of a working device using only a single layer of molded polydimethylsiloxane (PDMS

140 More importantly, APOM uses only a single lens near the sample to achieve selective-

141 post-diagnostic interventions assuming that only a single lesion progresses to invasive carcinoma du

142 spontaneously even in a membrane containing only a single lipid component.

143 uish between hemifusion and full fusion with only a single lipid dye, thereby freeing up a fluorescen

144 d locations, transistor fabrication requires only a single lithographic step.

145 Only a single local recurrence occurred in cases with no

146 existing location prediction systems assign only a single location per protein.

147 more likely to grow than those representing only a single location.

148 ps within this group have been studied using only a single locus (the rRNA operon), leaving the origi

149 sence of an escape tunnel is associated with only a single locus.

150 ding over 40 kbp of the VGSC 1575Y occurs on only a single long-range haplotype, also bearing 1014F.

151 ty de novo microbial genome assemblies using only a single, long-insert shotgun DNA library in conjun

152 o sophisticated nanofabrication and utilizes only a single low-cost diode laser.

153 antimicrobial-exposed patients, and requires only a single LRT specimen.

154 Klebsiella, and Enterobacter genera possess only a single LuxR homolog, SdiA, and no acyl-HSL syntha

155 Although only a single MAGE gene exists in lower eukaryotes, the

156 Only a single mammalian STUbL, RNF4, has been identified

157 he predominant oligomeric forms of MBL carry only a single MASP homodimer.

158 In angiosperms, only a single maturase has been retained in the mitochon

159 Invertebrates generally have only a single MBD protein, MBD2/3, that does not always

160 vironments are still poorly understood, with only a single member of this genus (Ca. N. devanaterra)

161 ich may be quite numerous, or may consist of only a single member.

162 ugh complex "pipelines", even in cases where only a single metabolite or peak is of interest.

163 on of dinuclear palladium complexes, wherein only a single metal center is directly involved in the c

164 uce YSNs that cannot be obtained directly by only a single method.

165 H3 K79 methylation, which is carried out by only a single methyltransferase, disruptor of telomeric

166 implest of Type IV pilus systems and possess only a single minor pilin.

167 nefits of amphibian embryology but crucially only a single Mix and Nodal gene required for the specif

168 r strategy is simple to implement, requiring only a single mixing step at room temperature for each o

169 tional systemic antimicrobial agents, having only a single mode or site of action, will not alleviate

170 Its biosynthetic gene cluster contains only a single-module polyketide synthase-nonribosomal pe

171 multidimensional grid methods, assures that only a single molar mass can be associated with a given

172 Although only a single molecule of alphaSNAP binds to a soluble f

173 while in liver and adipose tissues extracts only a single monohydroxy-pentabromocyclododecane metabo

174 ter if they are polymorphic than if there is only a single morph present in the population.

175 of Hfq-binding sRNAs but surprisingly target only a single mRNA, which encodes the outer membrane lip

176 Most mutants carry only a single mutation.

177 -rabbit host jump over 40 years ago and that only a single naturally occurring nucleotide mutation wa

178 Until recently, only a single naturally occurring stereochemical configu

179 The last two decades have produced only a single new drug but have represented a renaissanc

180 ften can be assembled in a few contigs using only a single Nextera Mate Pair library of short reads.

181 In fact, only a single non-enzymatic domain within SypF, the HPt

182 Only a single non-silent somatic alteration was detected

183 % of GPR42 haplotypes differed from FFAR3 by only a single non-synonymous substitution and that the G

184 o-temperature approximation and assumed that only a single nuclear species was present at any given d

185 sented here that the R1162 relaxase contains only a single nucleophile capable of cleaving at oriT, w

186 scriminate it from miR-10a, which differs by only a single nucleotide (12th base from the 5' end), an

187 omparison with similar microRNA differing by only a single nucleotide (hsa-let-7c) and random microRN

188 ns, and an additional 12% (6/51) differed by only a single nucleotide across a 603-bp region of the p

189 r naturally occurring allele that differs by only a single nucleotide polymorphism (SNP) does not.

190 This structure persists even when only a single OH group is present in the HD2O(+) isotopo

191 n AZ harbors 4 docked vesicles in human, but only a single one in rats.

192 roportion of patients with severe sepsis and only a single organ dysfunction decreased from 51% in 20

193 n algae express many different OPR proteins, only a single orthologous OPR protein is encoded in the

194 We find only a single oscillatory component with no signatures o

195 Only a single OTU, TM7-3a, was found to increase with sl

196 Discussion: Although only a single outcome indicator goal (at least 10% annua

197 t and protein is turnover-dependent and that only a single oxygen is exchanged into the protein even

198 ning, in which the brain learns rapidly from only a single pairing of a stimulus and a consequence.

199 , our single-layer model with CSN or DSN and only a single parameter achieved a prediction performanc

200 Only a single parasite (Haemoproteus nucleocondensus) wa

201 In trees, vertices may have only a single parent (ancestor), while networks allow fo

202 anisms in Saccharomyces cerevisiae, although only a single pathway and E3 ubiquitin ligase for Cdc6 h

203 Hermansky-Pudlak syndrome type 2 (HPS2), but only a single patient was reported who developed HLH.

204 All potentially translatable lncRNA ORFs had only a single peptide match, indicating low protein abun

205 the enteric pathogen Vibrio cholerae, encode only a single PG amidase, AmiB.

206 rmal titration calorimetry all indicate that only a single PG9 fragment antigen-binding (Fab) binds t

207 ring human pancreas development, we detected only a single-phase of Neurogenin 3 (NEUROG3) expression

208 an result in faster range expansions than if only a single phenotype were present in the landscape.

209 e population of individuals that can express only a single phenotype.

210 p38alpha bearing only a single phosphocysteine (pCys) as a mimic of pThr

211 present a mechanism by which organisms with only a single photoreceptor, which have a monochromatic

212 ugh this method requires no electricity, and only a single piece of inexpensive equipment, it can mea

213 ince this method requires no electricity and only a single piece of inexpensive equipment, it may fin

214 -free, rapid, highly sensitive, and requires only a single pipetting step.

215 measures, and they had to rely on data from only a single point in time (2000-2001).

216 dies that differ from their parental mAbs by only a single point mutation per heavy chain.

217 is designed with the two criteria of having only a single point of S-S scission and maximizing the r

218 amily in the 1990s, the de novo synthesis of only a single polycyclic furanobutenolide-derived cembra

219 le isoforms are expressed at the mRNA level, only a single polypeptide that co-migrates with the huma

220 mpared with 82.8% for PLS-DA) occurred using only a single pre-processing step.

221 1% in vivo with reduced tissue damage, since only a single probe needed to be implanted.

222 Only a single product was observed in each case.

223 The human gene uses only a single promoter, whereas the mouse uses two: P2,

224 In contrast to mammalian HOs, NmHO requires only a single propionate interacting with the buried ter

225 occurs from within these precursors, and yet only a single protease monomer is embedded in each polyp

226 Whereas most viruses require only a single protein to bind to and fuse with cells, he

227 In contrast, the B-type CcO uses only a single proton input channel for all consumed and

228 s, but current biochemical techniques detect only a single proximity partner per probe.

229 Moreover, only a single pure diastereomer, derived from attack of

230 e yield of each step is >91% and it requires only a single purification step.

231 Most studies have considered only a single putative causal agent and have failed to r

232 The Streptomyces coelicolor genome encodes only a single putative lipoate ligase.

233 We show here that using only a single RED cell pair (CP), created by operating t

234 Because there is only a single redox moiety the faradaic process occurs a

235 ain to the oxidase domain, which reveal that only a single reductase domain participates in electron

236 However, there is only a single report of RDX degradation in training rang

237 Even when the TMDs differ in length by only a single residue, hydrophobic mismatch can segregat

238 d with success and failure typically examine only a single resource domain, have limited geographic s

239 electronic properties, despite differing by only a single ring in the link between the PDI units.

240 bullet-shaped GroEL/GroES complexes in which only a single ring is capped by GroES interact with the

241 osed to explain this result by assuming that only a single row of vortices is allowed inside a nanowi

242 ies receiving large numbers of specimens, as only a single sample can be processed at a time with one

243 Fourth, only a single sample incubation step is required before

244 ly, we measured quantifiable PBDE burdens in only a single sample of predaceous ground spiders from t

245 DeepCyTOF requires labeled cells from only a single sample.

246 ntain costs often results in the creation of only a single sequencing library, which in turn introduc

247 Adding only a single series resistor to existing AC droplet act

248 y a few species stably to coexist, including only a single shade tolerant.

249 quid crystalline behavior in spite of having only a single side chain.

250 Alternatively, if only a single site is involved, GpIbalpha may serve as a

251 t positive allosteric modulators (PAMs) have only a single site per dimer.

252 on in exposure estimation arising from using only a single site.

253 the periphery of the bulk MOF crystals with only a single SMM molecule isolated in the transverse di

254 ric analyses support the idea that there was only a single species of middle to late Pleistocene NWSL

255 ixture of two DNA molecules, each possessing only a single specific site, indicate that transfer betw

256 body emission and pronucleus formation after only a single sperm-induced Ca(2+) transient, whereas BA

257 ermy and ensure that eggs normally fuse with only a single sperm.

258 ared with the CAR(tcp):RXR.SRC1, which binds only a single SRC1.

259 The presence of only a single Stat5a or Stat5b allele was sufficient for

260 thography for the print of the features, and only a single-step surface pretreatment is needed.

261 g disease was consistent with infection with only a single strain.

262 whereas 2 women had acute HEV detectable at only a single study visit.

263 ide polymorphism, unannotated and present in only a single subject, directs alternative splicing of e

264 y few SNVs (average of 5.9 per megabase) and only a single SV.

265 Nine (64.3%) had only a single symptom.

266 This requires building only a single system-specific construct by placing a tar

267 indicate that modification or disruption of only a single target nucleosome results in significant c

268 Because there is only a single TBT unit present, there is little scope fo

269 n studies of virus epidemiology that rely on only a single test at symptom onset.

270 elix, whereas prokaryotic SemiSWEETs contain only a single THB and require homodimerization to form t

271 ith escape mutants were 100% protected after only a single therapeutic dose of the antibody used to g

272 were compared to a model compound containing only a single thiophene-substituted quinoxaline ring.

273 urate short-term forecasts, even while using only a single time series from the multivariate system.

274 The other two isoforms contain only a single TPS domain.

275 C. trachomatis phylogeny show that there is only a single trachoma-causing clade, which is distinct

276 hieved without cumbersome circuitry and with only a single transducer, thus significantly reducing sy

277 on-adapted mammalian cell lines and requires only a single transfection step.

278 r insertion that encodes proteins containing only a single transmembrane (TM) domain.

279 domains, whereas metazoan Mitofusins contain only a single transmembrane domain.

280 utations in CCHFV recovered from ticks after only a single transstadial transmission, whereas none we

281 udy was that dexamethasone patients received only a single treatment during the 6-month study.

282 gm, memory requirements are minimized (often only a single tree or sequence in memory at any instance

283 s subsequent fear conditioning training with only a single trial.

284 either model complexes containing no tRNA or only a single tRNA, or complexes where EF-G was directly

285 sing five separate proteins, each containing only a single tryptophan residue, that the rate constant

286 This requires only a single tunnel contact to the nanoparticles thus s

287 athways that would have been overlooked with only a single type of data, uncovered associations betwe

288 s, most glycomics databases allow storing of only a single type of experimental data.

289 Each recombinant BaF3 cell line expresses only a single type of fibroblast growth factor receptor

290 an that observed in modules identified using only a single type of genomic data.

291 ut how Bre1 directs Rad6 toward transferring only a single ubiquitin to a specific lysine residue.

292 The device requires only a single user step and delivers (i) the sample, (ii

293 Individual parasites express only a single var gene at a time, maintaining the remain

294 lation of var gene expression, ensuring that only a single var gene is expressed at a time while the

295 cular phenotypes in model systems expressing only a single VEGF isoform.

296 sure doses in humans that typically transmit only a single virus.

297 last ablation, VT-free survival was 71% with only a single VT episode in additional 9 patients (15%).

298 crococcal nuclease digestion, sufficient for only a single wrap of DNA around the cenH3 nucleosome co

299 h diastereoselectivity during catenation, as only a single (Z)-isomer is formed.

300 d to conditions with vertical disparity--has only a single (zero) disparity channel and embodies both