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1 approach (including procedures converted to open).
2 a depolarized conformation, and the pore is open.
3 he membrane deformation changes upon channel opening.
4 rmation by alamethicin or Ca(2+)-induced PTP opening.
5 ane ODH after thermal activation under O2 to open a cobalt coordination site and to oxidize Co(II) to
6 encourage undergraduate physics students to open a discussion on the fundamental assumptions in ther
8 ient separation is the formation of Jupiter, opening a gap in the disk and preventing the exchange of
9 smoprotective emergency valve in bacteria by opening a large, water-filled pore in response to change
10 species co-occurs with other cuckoo species, opening a new avenue for standardized citizen science on
11 e used to identify drug-target interactions, opening a new research direction in target identificatio
12 a class of hybrid supramolecular composites, opening a window into fiber technology through low-energ
13 can readily be adapted to other species and opens a door to detailed investigations of inelastic or
18 CTGU-5 which has coordinates water and more open access to the cobalt site has higher electrocatalyt
21 p for substrate guidance and have an unusual open-access copper site, yet they can still react with s
23 ort to enroll many participants to create an open-access repository of genome, health and trait data
26 tion results in increased retro-Bergman ring opening, allowing C(1)-C(5) cyclization to become a comp
27 F56Bpa and F57Bpa KCNE1 were cross-linked in open and closed states, respectively, which suggests tha
28 sted by the U.S. government have fostered an open and collaborative environment for the development o
30 eve better outcomes, and explain why we need open and international discussions concerning a technolo
34 ion of the nucleotide binding domains drives opening and closing of the MacB periplasmic domains via
36 uctural changes in mtRNAP to enable promoter opening and trapping of the DNA non-template strand.
38 culoplasty (SLT) as sole therapy for primary open-angle glaucoma (POAG) in an Afro-Caribbean populati
42 ed in the study, 22836 (25.3%) had undergone open aortic surgery and 67467 (74.7%) had had infraingui
43 e codes were used to determine the either an open approach or a laparoscopic approach (including proc
47 models, that will deepen our understanding, open avenues for research and provide an important refer
48 al coherence tomography (OCT) Bruch membrane opening (BMO) algorithm and stereoscopic optic disc phot
49 lution to the bryostatin supply problem also opens broad, facile, and efficient access to derivatives
51 lly controlled vascular gateway specifically opens by cleavage of NPY by CD26 signaling via NPY2 and
52 s a highly compact conformation in which its open Ca(2+)-activated C-lobe and closed N-lobe cooperate
56 sistent with the RyR1 and cardiac RyR (RyR2) open-channel structures reported while this paper was in
58 hat crossovers reside in genomic regions of "open chromatin", which were identified based on hypersen
59 ueisser limit, but they suffer from a larger open circuit voltage (VOC ) deficit than narrower bandga
61 We show the FEC condenses on the surface at open circuit voltage then is reduced to C-O containing p
62 electrochemical impedance analysis (EIS) and open-circuit potential decay transients (OCVD), which at
63 SAED, EDX, XPS, UV-visible spectroscopy, and open-circuit potential versus time experiments to unders
64 r-conversion-efficiency of 7.26% with a high open-circuit voltage of approximately 1 V and a striking
65 Thus, IOIC2-based OSCs show higher values in open-circuit voltage, short-circuit current density, fil
66 are beneficiaries undergoing laparoscopic or open colectomy between January 1, 2010, and December 31,
67 sence of calcium, are compacted but adopt an open conformation in the presence of calcium, enabling a
68 PK1 exhibits preferential binding toward the open conformation of vinculin, suggesting that the MAPK1
69 rganization requires the protein to adopt an open conformation that exposes the surfaces engaging in
70 post-chemistry structure of hPolbeta in the open conformation, following incorporation of (-)3TC-MP,
74 thod and demonstrate pathways for the closed-open conformational transition in both directions by com
77 ed because the beta2 extension and headpiece opening could occur independently of the alphaI activati
78 ) or porous coordination polymers (PCPs) are open, crystalline supramolecular coordination architectu
84 low cost and modular nature as well as fully open design of FlyPi make it a highly versatile tool in
87 aking roofs were repaired, windows screened, open eaves blocked with bricks and mortar, cement floors
88 experiment (metadata) is in the format of an open-ended, non-standardized textual description provide
96 ere the aldol condensation, cyclopropyl ring opening followed by cyclization took place in a single-p
97 btained at different institutions and is now open for further validation in gliomas and other cerebra
98 est that as new regions of the genome become open for transcription during terminal differentiation,
99 e soft X-ray range with a laboratory source, opening, for example, the possibility of in-line or even
100 nstrated to control the thermal expansion in open-framework materials by adjusting the presence of gu
102 l 3-year survival was 40.4% (SD 7.7%) in the open group versus 50.5% (SD 8%) in the minimally invasiv
104 that G100V/C103V retards initial fusion-pore opening, hinders its expansion and leads to premature cl
105 can pass directly through the endothelium by opening holes in endothelial cells, known as transcellul
106 These compounds crystallize to form robust open hydrogen-bonded networks with parallel indenofluore
107 tend our understanding of human CSF flux and open important clinical implications, including concepts
109 demonstrate that the mechanisms of pore gate-opening-induced and relaxation-induced voltage-sensor st
112 controlled study involving 186 patients; an open label extension study performed after the phase 3.
113 isense oligonucleotide targeting exon 51: an open label study including 12 patients; a phase 3 random
114 lic blood pressure (130-149mmHg vs <130mmHg; open label) and to antiplatelet treatment (aspirin/clopi
121 -time reduction was sustained throughout the open-label phase (-126.3 minutes at 1-year open-label en
124 ere randomly assigned (2:1) to switch to the open-label study regimen or continue the control regimen
125 ontrolled study for 16 weeks, followed by an open-label study with overall 40-week DHA treatment.
129 gmatic, multicenter, randomized, controlled, open-label trials with blinded outcome evaluation: the P
130 n HIV-1 infected individuals (SWIFT-C) is an open-label, 2-cohort clinical trial in which the first c
131 he final analysis from GATSBY, a randomised, open-label, adaptive, phase 2/3 study, done at 107 centr
132 er, parallel-group, prospective, randomized, open-label, blinded end point trial, consenting patients
133 d an international, prospective, randomised, open-label, blinded-endpoint trial in adult participants
134 is multicentre, parallel group, superiority, open-label, blinded-endpoint, randomised controlled tria
142 Patients and Methods In this multicenter, open-label, phase III trial, 2,012 women with early TOP2
144 on, we conducted a prospective, multicenter, open-label, randomized phase III trial that compared a b
149 over 18 years of age scheduled for elective open lobectomy or bilobectomy for malignancy were eligib
150 andom order: hyperinflation, 6 cm H2O above; open lung approach, 2 cm H2O above; and collapse, 6 cm H
152 ckpoint is the conformational conversion of "open" mitotic arrest deficient 2 (O-MAD2) into "closed"
154 pericardial resection in normal canines with open (n=3) and closed chest (n=5) and in a pig model wit
155 tructures of nanoclusters and is expected to open new avenues for designing nanoclusters with novel s
156 imaging using (89)Zr-Df-ALT-836 promises to open new avenues for improving future diagnosis, stratif
158 eir chemical versatility for adaptation will open new opportunities for applications built upon diver
159 e cell-cell communication structure - it may open new opportunities for identifying molecular signatu
164 nvironment in planar chromatography but also opened new avenues and new perspectives for tailor-made
165 (TMDs) as atomically thin semiconductors has opened new frontiers in semiconductor heterostructures e
167 n via altering its charge distribution, thus opening new possible roles for betaS in Parkinson's and
170 e machines recently introduced in the market opens new expectations in the field of espresso brewing.
171 ence of empirical and computational advances opens new frontiers of scientific inquiry, including net
174 d functions of differentiated cell types and opens new research avenues into epithelial trafficking.
175 printing of functional materials and devices opens new routes for the biointegration of various senso
177 on of the vocal behaviour of penguins in the open ocean and discuss the function of their vocal commu
178 doles via Lewis acid-catalyzed SN2-type ring opening of activated aziridines with indoles having subs
179 butadiene with ethylene, electrocyclic ring-opening of cyclobutene, electrocyclic ring-closing of Z-
180 ient low-cost method for regioselective ring-opening of donor-acceptor cyclopropanes with the Zn-AcOH
182 chable following the reversible ring closure/opening of the central dithienylethene via irradiation w
185 pensity score-matched analysis of robotic vs open pancreatoduodenectomy to date, and it demonstrates
186 S. admonitor trees to paternity in seed from open-pollinated flowers of S. subcuneata decreased rapid
188 .1 in giant liposomes, resulting in a higher open probability due to more frequent opening bursts.
189 mistry, a novel C-N bond activation and ring-opening process is described for these increasingly impo
192 arbon nanotubes (CNTs) has been an important open question since the first reports of the strong modu
196 al stimuli and simplified behaviors, leaving open questions about nervous system function in the cont
197 ll also point out some of the most important open questions in the field and emerging evidence sugges
198 Our analysis of the key uncertainties and open questions of and beyond the inventory shows that, a
199 Finally, we discuss major challenges and open questions related to the application of SERS for un
200 domonas, and Stentor coeruleus Although many open questions remain, elucidating how cells repair them
203 mide is unprotected, the characteristic ring-opening reaction is completely silenced, which explains
204 which explains that the majority of the ring-opening reactions reported in the literature invoke N-al
205 P24), angiopoietin 4 (ANGPT4), chromosome 11 open reading frame (C11orf30/EMSY), and exocyst complex
207 ransmembrane protease, serine 2) gene to the open reading frame of ERG, encoding an ETS family transc
208 on enhancing factor (PTEF) relieves upstream open reading frame repression and thereby facilitates VA
211 iversity leading to the formation of altered open reading frames (ORFs) that appear to be under relax
215 ication of nanoparticle-based drug delivery, opening several exciting avenues for selective and prolo
220 lipidomics, we developed LipidHunter, a new open source software for the high-throughput identificat
221 they produce for data analysis and modeling open source, and are actively encouraging their colleagu
223 oduce analytical chemists who are new to the open-source movement to best practices and concepts in t
225 ation in single particle cryo-EM and present open-source software for rapidly assessing orientation d
226 rowing need for a user-friendly, extensible, open-source solution for digital pathology and whole sli
229 ed within 100 m of each location when it was open (spatiotemporal coverage) for Toronto overall and d
230 Failure of this closure process leads to open spina bifida, a common cause of severe neurologic d
232 sted that F56Bpa interacts with KCNQ1 in the open state, whereas F57Bpa interacts predominantly in re
233 ity by increasing intrinsic stability of the open state, whereas the cluster of Y981S/G985E/M1056I su
234 The SGC plants showed a loss of ability to open stomata in anticipation of daily dark-to-light chan
236 chnique (RKT) versus patients performed with open surgery at all US centers including our own (open k
239 prohibitive surgical risk and, therefore, an open surgical procedure may not be feasible or appropria
240 N-terminal acidic region of Ng peptide pries open the beta-sheet structure between the Ca(2+) binding
241 Approaches such as those presented here may open the door for accurately determining intermolecular
242 amino acid at POmega, which enabled them to open the F pocket and expose their C-terminal extension
244 nterferometer Gravitational-wave Observatory opened the door to alternative probes of stellar and gal
246 ins are targetable by dietary interventions, opening the avenue to a precision intervention for patie
247 y is possible in other chalcogenide spinels, opening the door for the realization of other magnesium
248 observation of Bi-B double and triple bonds, opening the door to design main-group metal-boron comple
249 gahertz response of metallic nanostructures, opening the door to new optomechanical device strategies
250 timulates a depolarizing chloride current by opening the olfactory Ca(2+)-activated chloride channel
251 ins similar antigenicity to wild-type virus, opening the possibility for its use as a live-attenuated
252 human biomonitoring at the community scale, opening the possibility to assess population-wide exposu
253 veral orthogonal split intein pairs, thereby opening the way to the creation of multiplexed sensor sy
255 ther optically/IR-transparent organisms, and opens the door to high-resolution systematic analyses of
259 to easily label pericytes in any mouse model opens the possibility of a broad range of investigations
262 as been shown to promote CNG and HCN channel opening, the precise mechanism underlying gating remains
265 g reaction is performed at room temperature, open to atmosphere, and without the need to rigorously e
266 ince the mid-1980s, but the term survivor is open to debate by people living with cancer and those ca
267 ticenter, phase 3, randomized clinical trial open to patients with biopsy-proven carcinoma of the eso
270 peak twisting and untwisting at mitral valve opening (%untwMVO) using speckle-tracking echocardiograp
272 on the in vivo transport of ultrasmall AuNPs open up a pathway to maximize their biomedical potential
274 Such remote-controlled, smart films may open up new application possibilities in soft robotics a
275 large scale quantum information systems and open up new avenues for the design of artificial 2D mate
277 e detection of short RNA regions which could open up new opportunities in transcriptome analysis, vir
278 ree characterization of nanoscale structures open up new possibilities for assembly and control of na
280 biological knowledge graph, and will thereby open up the increasing amount of Semantic Web based know
282 y promising photonics-based chemical sensing opened up by the new guest@MOF composite systems is show
283 as revolutionized prenatal care globally and opened up new prospects for personalized medicine for th
285 quids to afford permanent porosity, and thus opens up a new approach to prepare porous carbon liquids
286 of-plane field in thick magnetic multilayers opens up a new set of tools and materials to study the p
287 tatetraenyl via a single-collision event and opens up a versatile, unconventional path to access this
291 oping control of structural phase transition opens up new possibilities for developing phase-change d
293 , by comparing the association of MAPK1 with open versus closed vinculin, we demonstrate that MAPK1 e
294 of kiri-kirgami, and their actuation of pore opening via both mechanical stretching and temperature,
296 Notably, the overall radiative forcing of open-water fluxes (3.5 +/- 0.3 kg CO2 -eq m(-2) yr(-1) )
297 circadian-mediated anticipation in stomatal opening, we have generated SGC (specifically guard cell)
299 r approximately 200 kinases by (1) combining open with proprietary data, (2) choosing Random Forest o
300 terventional procedure consisting of fissure opening with linear cutting staplers buttressed with pai
301 nformations, one of which is most likely the open-X structure which has unpaired bases at the junctio
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