ライフサイエンスコーパス: open new avenues for

1 The findings open new avenues for a more rational understanding of th

2 o be applied to other serine proteases, thus opening new avenues for a systematic discovery of serine

3 Macromolecular crowding opens new avenues for a more rational design in engineer

4 Importantly, it opens new avenues for accelerating the discovery of stab

5 C) is controlled by valence band holes, thus opening new avenues for achieving higher values of T(C).

6 It also opens new avenues for additional studies into a multitud

7 nto viral transmission and pathogenesis, and opens new avenues for AIDS therapy and prophylaxis.

8 These data may open new avenues for AMD treatment strategies.

9 Our results open new avenues for an innovative anti-VSMC foam cell-b

10 w self-assembling modular polymers that will open new avenues for applications in materials science.

11 e obtained on challenging templates, thereby opening new avenues for applications of Pyrosequencing t

12 mon-exciton interaction at the nanoscale and opens new avenues for applications in ultrafast nanophot

13 onic developmental potentials in culture and open new avenues for basic and translational research.

14 dothelial progenitors in tissue regeneration opens new avenues for better understanding of cardiovasc

15 ates a novel autoantigen in type 1 diabetes, opening new avenues for biomarker development and therap

16 This study opens new avenues for biomarker discovery and identifica

17 is-tag and electrostatic immobilization also opens new avenues for bivalent immobilization of protein

18 intein-triggered protein hydrogel technology opens new avenues for both in vitro metabolic pathway co

19 ammed cell death protein 1 [PD-1]) have both opened new avenues for cancer treatment, but the clinica

20 ing confocal and multiphoton microscopy, are opening new avenues for cellular exploration.

21 the structure of phospholipid membranes, and opens new avenues for characterizing the (nano)mechanica

22 surface albedo change on summer temperature opens new avenues for climate-engineering measures targe

23 Finally, our developed strategy could open new avenues for clinical screening and prognosis of

24 is reversible by pharmacological agents has opened new avenues for clinical intervention.

25 r topological model for spatial learning and open new avenues for connecting data at the level of ind

26 This approach also opens new avenues for consecutive one-pot multicomponent

27 This approach opens new avenues for continuous delivery of healing age

28 human and murine macrophage biology and may open new avenues for controlling the fatty acid-related

29 ce our understanding of virus cell entry and open new avenues for curative therapies.

30 These findings might open new avenues for defined conjugations of small molec

31 Our study opens new avenues for defining GSK3 isozyme-specific fun

32 Furthermore, this work may open new avenues for designing and fabricating advanced

33 expected that DNA-mediated 2D SNL structures open new avenues for designing miniaturized plasmonic na

34 tructures of nanoclusters and is expected to open new avenues for designing nanoclusters with novel s

35 Our study will open new avenues for designing novel self-assembled NCs

36 These findings open new avenues for developing antibiotics that specifi

37 These findings open new avenues for developing antiviral strategies to

38 ases of the Central Nervous System and could open new avenues for developing efficacious antispastic

39 functionally to our social lives, which may open new avenues for developing innovative treatments fo

40 It may open new avenues for developing novel technology platfor

41 anisms that mediate chromosomal fusions will open new avenues for developing therapeutic strategies a

42 tic development of thiol-based materials and opens new avenues for developing novel bioanalytical tec

43 that siRNNs represent a technology that will open new avenues for development of RNAi therapeutics.

44 ure, function, and signaling of RAS and have opened new avenues for development of much needed new th

45 These 3D micro-engineered environments open new -avenues for drug screening and fundamental stu

46 arities to bacterial and plant counterparts, opens new avenues for drug development.

47 These data may open new avenues for early detection and appropriately t

48 This pipeline opens new avenues for early disease diagnostics and drug

49 in RAC synthetic and electrochemical design opens new avenues for energy storage.

50 eractions that mediate exotic phase diagrams open new avenues for engineering emergent properties.

51 d in room-temperature ferroelectric devices, opening new avenues for engineering ferroelectric thin-f

52 function or its downstream sequelae, thereby opening new avenues for enhancing vaccine efficiency in

53 alkaline-earth/oxygen layer in the templates opens new avenues for epitaxial growth of ferropnictides

54 n of leptin production by adipose tissue and open new avenues for examining the influence of variatio

55 smonic nanovortices introduced in this study open new avenues for exciting applications of orbital an

56 omising method of meeting this challenge and open new avenues for exploring energetics in natural set

57 mical properties of nonplanar porphyrins and open new avenues for exploring photoinduced ligand assoc

58 yme-DNA complexes can form, a discovery that opens new avenues for exploring and exploiting relations

59 This approach opens new avenues for fabricating reconfigurable nanoant

60 uggest that its antimicrobial activity could open new avenues for fighting infections caused by multi

61 hway with a low rate of false positives that opens new avenues for function profiling of human genes

62 ol of GABA(A)Rs by an allosteric ligand, and open new avenues for fundamental and clinically oriented

63 f VO2 films as an electrochemical sensor and open new avenues for further electrochemical research us

64 ation of vomeronasal information coding, and opens new avenues for further investigating the neural m

65 The discovery of this form opens new avenues for further investigation of the role

66 ght regarding Zn-exporters in PCa, which may open new avenues for future studies aimed at enhancing t

67 ogen and within different pathogenic strains opening new avenues for future explorations.

68 the maturity of the microchip technology and opening new avenues for future implementation of screeni

69 tification of XCR1(+) mDC in rhesus macaques opens new avenues for future preclinical vaccinal studie

70 are TIMPs in soluble or ECM-bound forms also opens new avenues for future TIMP research.

71 These findings also open new avenues for gas sensing and isotope separation.

72 a powerful tool for biological research and opens new avenues for genetic manipulation in birds.

73 o over similar films on macroscopic surfaces opens new avenues for genotoxicity screening and enabled

74 development of NMDA receptor antagonists has opened new avenues for glutamatergic, rapid acting, anti

75 deep-subwavelength-scale field confinement, opening new avenues for highly efficient next-generation

76 The use of DEN-gas opens new avenues for highly sensitive sheathless CE-ESI

77 Our work opens new avenues for ice core research.

78 e-mediated suppression of carcinogenesis may open new avenues for identification of therapeutic targe

79 These studies open new avenues for identifying complex disease genes a

80 f specific inner plexiform layer sublaminae, opening new avenues for identifying novel diagnostic and

81 imaging using (89)Zr-Df-ALT-836 promises to open new avenues for improving future diagnosis, stratif

82 the plasticity of crystalline materials and opening new avenues for improving their strength and duc

83 The proposed method opens new avenues for improving structure characterizati

84 dren's Health Insurance Program (SCHIP) have opened new avenues for increasing coverage rates.

85 nd consequential addiction to EGFR signaling opens new avenues for inhibiting PRL-3-driven cancer pro

86 d bacteria in realistic environments, and it opens new avenues for interesting applications such as t

87 sinase as a potential GPR143 binding protein opens new avenues for investigating the mechanisms that

88 The technique described opens new avenues for investigating the neural basis of

89 provide new insight into 53BP2 function and open new avenues for investigation into the cellular res

90 ufficient tumor suppressor and, importantly, open new avenues for investigation into the mechanisms b

91 the genesis of acute herpetic neuralgia and open new avenues for its control.

92 ed in the genesis of acute herpetic pain and open new avenues for its control.SIGNIFICANCE STATEMENT

93 f calicivirus-associated diarrhea, and it is opening new avenues for its prevention and control.

94 These results open new avenues for label-free time-resolved investigat

95 Thus, ISFC opens new avenues for linking brain network dynamics to

96 oduce lignin from alternative monomers would open new avenues for manipulation of lignin by genetic b

97 This approach opens new avenues for mapping and manipulating neural ci

98 zed pathway operating in iPSC induction will open new avenues for mechanistic dissection of the repro

99 The novel phospholipid-recycling scheme opens new avenues for metabolic engineering of lipid com

100 reat potential for novel surface patterning, opening new avenues for molecular level information stor

101 Our approach also opens new avenues for multiscale processes of biomolecul

102 completion of the Drosophila genome sequence opens new avenues for neurobiology research.

103 ecent advent of pluripotent cell biology has opened new avenues for neurodegenerative disease researc

104 range of neurodegenerative diseases and may open new avenues for neuroprotective intervention.

105 tems that suffer from internal dynamics, and opens new avenues for NMR spectroscopy at very high magn

106 Our design approach opens new avenues for optically controlling enzyme funct

107 ing homeostatic CD8 T cell proliferation and open new avenues for optimizing lymphoablative therapies

108 tain discrete Fourier transform vectors, and opens new avenues for optoelectronic devices.

109 nces in the distribution of information have opened new avenues for patient care.

110 lation of non-genomic estrogen signaling and open new avenues for personalized therapeutic approaches

111 ticide sprays, showing that transgenic crops open new avenues for pest control.

112 modeling has been widely appreciated and has opened new avenues for pharmacological research.

113 endent phosphorylation in heart disease will open new avenues for potential therapeutic approaches ag

114 They have also opened new avenues for potential therapy.

115 This therapeutic approach opens new avenues for preclinical and clinical studies t

116 echanism may be conserved in mammals and may open new avenues for prevention of arterial thrombosis.

117 The local probing capabilities of ST-UEM open new avenues for probing dynamic processes, from sin

118 low-affinity biologically relevant systems, opening new avenues for probing carbohydrate-protein int

119 AIL receptors to protect hHSC from apoptosis opens new avenues for prognostic and therapeutic approac

120 roteins mediated by the AT system and should open new avenues for protein display and engineering.

121 or fine resolution of protein conformers may open new avenues for proteoform separations in top-down

122 This finding opens new avenues for quantum computing based on molecul

123 These findings open new avenues for rational protein design and fundame

124 ivial Berry phases in the spin lattice, thus opening new avenues for realizing topological spin model

125 These discoveries open new avenues for research in asthma and allergy, and

126 t stimulation and cell survival by GPCRs and open new avenues for research on the function of the lar

127 CHD2 does not encode an ion channel, opening new avenues for research into human cortical exc

128 The preservation of chitin in these fossils opens new avenues for research into other ancient fossil

129 This approach opens new avenues for research on the mechanism of actio

130 The results open new avenues for studies of insect immunity, transmi

131 NE and non-NE hyperplasia/neoplasia in vivo, opening new avenues for studies of lung carcinogenesis.

132 This method opens new avenues for study of B(12) assimilation.

133 The model will open new avenues for studying the causes of the optic ne

134 Our study opens new avenues for studying itch and developing anti-

135 Our approach based on SMLM opens new avenues for studying structural and functional

136 nfection closely resembles human disease and opens new avenues for studying the pathogenesis of sexua

137 pment of this model of oligonucleosomes thus opens new avenues for studying the role of histone tails

138 ncy of perceptual learning success in humans opening new avenues for supportive learning tools in the

139 oving impasses to material preparation, thus opening new avenues for synthesis.

140 is Pd-catalyzed cross-coupling reaction will open new avenues for synthesizing useful compounds.

141 These results open new avenues for synthetic, non-biological antibody

142 ibute to borderline psychopathology and even open new avenues for targeted pharmacotherapeutic approa

143 he pathogenesis of inflammatory diseases may open new avenues for targeted therapies.

144 1 promoter will be highly tumor specific and open new avenues for targeting a broad range of cancers.

145 ing approaches to rejuvenate HSCs, which may open new avenues for targeting SIR in the clinic.

146 into HIF-mediated transcription but also may open new avenues for targeting the HIF pathway for cance

147 progression beyond the RAF-MEK-ERK paradigm, opening new avenues for targeting RAF in cancer.

148 in-dependent regulation of cell motility and open new avenues for tetraspanin-targeted reagents by th

149 are represented in real neural circuits and open new avenues for the analyses of neural data.

150 sults demonstrate that the use of CSIA could open new avenues for the assessment of photosensitizatio

151 harmacotherapy of cocaine abuse and may also open new avenues for the characterization of opioid rece

152 ng in line with the 'One Health' concept may open new avenues for the control of these devastating di

153 with a lower risk for developing cancer and open new avenues for the design of immunotherapeutics re

154 This unexpected finding may open new avenues for the development of anti-HCV drugs.

155 in mammalian Huntington's disease models and open new avenues for the development of neuroprotective

156 Because of its potential to open new avenues for the development of optical sensors

157 s of the host response to P. aeruginosa will open new avenues for the development of successful preve

158 ontrolling these transcriptional modules may open new avenues for the development of therapeutic stra

159 sity lipoprotein metabolism and function and open new avenues for the development of therapeutics for

160 f wild-type and mutant Norrins reported here open new avenues for the development of therapeutics to

161 In addition, our study may open new avenues for the diagnosis and treatment of huma

162 n the protein concentrations, these findings open new avenues for the inhibition of the HbS polymeriz

163 The observations open new avenues for the multifunctional all-conjugated

164 sses that maintain the renal vasculature may open new avenues for the preservation of renal structure

165 ring conventional chemotherapy regimens, and open new avenues for the search of more effective therap

166 These findings open new avenues for the specific prevention or treatmen

167 This labelling scheme will open new avenues for the study of challenging proteins b

168 This may open new avenues for the study of ion pumps and similar

169 This is significant, because it may open new avenues for the study of molecular mechanisms u

170 hermore, we conclude that these mouse models open new avenues for the study of vitamin D metabolism a

171 te the antiangiogenic action of p75(NTR) and open new avenues for the therapeutic use of p75(NTR) inh

172 These results open new avenues for the transport of materials in denta

173 ttern of receptor expression, these findings open new avenues for the treatment of anxiety disorders.

174 is direct in vivo reprogramming approach may open new avenues for the treatment of chronic liver dise

175 ng pathway to cystic kidney diseases and can open new avenues for the treatment of diverse ciliopathi

176 These new findings may open new avenues for the treatment of dyslipidemias.

177 nowledge about the LDL-R family members will open new avenues for the treatment of many disorders.

178 Our results may open new avenues for the treatment of platelet productio

179 Targeting this pathway may open new avenues for the treatment of SCIs.

180 ophrenia, may become a major focus that will open new avenues for the treatment of this disease.

181 of estrogen and their mode of production and open new avenues for the understanding of estrogenic eff

182 The results of this study open new avenues for the use of a selective ERbeta agoni

183 ype site-specific recombinases (T-SSRs) have opened new avenues for the predictable modification of g

184 eparable binding surfaces for CRF and Ucn 1, opening new avenues for the design of ligand-specific an

185 port a role for CtsD in apoptosis during AKI opening new avenues for the treatment of AKI by targetin

186 miRNAs play in these processes, potentially opening new avenues for the treatment of dyslipidemias.

187 The fabrication of such colloids opens new avenues for the application of bioparticles an

188 of microtubules directed by E-fields, which opens new avenues for the design of biomolecular nanotra

189 entification of these inactive conformations opens new avenues for the design of efficient therapeuti

190 s, growth factor receptor and integrins, and opens new avenues for the development of pro- and antian

191 This approach opens new avenues for the digital assembly of functional

192 d abnormal SYN in the pathogenesis of PD and opens new avenues for the discovery of more effective th

193 ce of repositories in materials development, opens new avenues for the discovery of more TIs in diffe

194 skite-oriented quantum materials repository, opens new avenues for the discovery of perovskite-oxide-

195 This opens new avenues for the exploration of adaptation of m

196 lf-assembly in the 10-microm-size regime and opens new avenues for the fabrication of complex, three-

197 been well tolerated for up to 26 months and opens new avenues for the management of patients with mi

198 The novel methodology opens new avenues for the measurement of absolute carbon

199 fluorinated poly(aryl thioethers), but also opens new avenues for the processing, fabrication, and f

200 Such arrangement opens new avenues for the study of strongly correlated c

201 This discovery opens new avenues for the treatment of iron deficiency i

202 wall signals and improving resolution really opens new avenues for the use of DNP-enhanced solid-stat

203 ility of chiral induction in MOFs, our study opens new avenues for the use of other guest molecules a

204 lucan phosphatase site-specific activity and open new avenues for their biotechnological utilization.

205 al reactions at different disease stages may open new avenues for therapeutic intervention and modifi

206 is of bacterial innate immune resistance can open new avenues for therapeutic intervention geared to

207 on using fCS fragments or their mimetics may open new avenues for therapeutic intervention.

208 of metastatic dormancy and reactivation and open new avenues for therapeutic intervention.

209 between GIP and OPN in adipose tissue might open new avenues for therapeutic interventions.

210 rlying FGF functions as a co-transmitter and open new avenues for therapeutic interventions.

211 ction of intracellular parasites and thereby opens new avenues for therapeutic control of nonhealing

212 dysfunction and apoptotic cell death, which opens new avenues for therapeutic intervention.

213 ewborns with Group B streptococcal infection opens new avenues for therapeutic intervention.

214 in mediating retinal effects in diabetes and open new avenues for therapeutics to treat the retinal c

215 ng strategies that activate this program may open new avenues for therapy in ischemic heart disease.

216 es in schizophrenia through GEI analyses and open new avenues for therapy.

217 e stem cell field is also advancing rapidly, opening new avenues for this type of therapy.

218 rontier of science that, if conquered, would open new avenues for treatment of neurological disorders

219 on the pathogenesis of cardiomyopathies and open new avenues for treatment of the disease.

220 mary cilia in the setting of VHL deficiency, opening new avenues for treatment with beta-catenin inhi

221 This finding opens new avenues for treatment of immune disorders base

222 Their work opens new avenues for treatment of neurodegenerative and

223 clude DNA, RNA, peptides, and carbohydrates, opening new avenues for ultrasensitive analysis of biomo

224 The combined AuNP/ATRP method reported here opens new avenues for ultrasensitive detection of protei

225 These studies open new avenues for understanding how embryonic morphog

226 Our results may open new avenues for understanding the mechanisms underl

227 present exciting areas of research that have opened new avenues for understanding normal eye developm

228 resentation can be modulated by TLR ligands, opening new avenues for understanding their mechanisms a

229 This opens new avenues for understanding and manipulating can

230 antiviral function of NCR(+) Vdelta1 T cells opens new avenues for understanding the pathogenic role

231 This work opens new avenues for understanding the structure and fu

232 dentification of the isolated compounds, and opens new avenues for use of nanomaterials for coupled i

233 anisms of development of face perception and open new avenues for using fMRI adaptation to study the

234 This will open new avenues for using tRNS to investigate brain fun

235 This opens new avenues for very low-cost platforms for genera