ライフサイエンスコーパス: open-chain

1 d chain and the collinear arrangement in odd-open chains.

2 The low-energy structures for the full open chain 58-72 peptide were then computed and were all

3 Open chain aldehydes generated in nucleic acids due to s

4 he Hsp90 inhibitory activity of radamide, an open chain amide chimera of geldanamycin and radicicol.

5 While the open-chain amidoxime functionalities do not bind V, the

6 (K*i(1/4)9 pM, third-generation) contains an open-chain amino alcohol cation with two asymmetric carb

7 eptide was threefold greater than that of an open-chain analog, and the cyclic conformation was requi

8 stereoselectivity to those obtained with an open-chain analogue indicated that the ring system does

9 15 that of inactivation by the corresponding open-chain analogue, 4-amino-5-fluoropentanoic acid (3a)

10 reorganized for Cu(II) coordination than its open-chain analogue, with an unusual additional stabiliz

11 although not as potent as the corresponding open-chain analogues.

12 hlorophosphines, providing approaches to new open-chain and cyclic catena-phosphorus frameworks.

13 ctivation of the receptors, Ala-substituted, open-chain, and truncated analogues were synthesized and

14 This suggests that, unlike the open-chain anlogue, the conformationally rigid analogue

15 A knot in an open chain (as distinct from a closed circle) is not rig

16 Examination of a series of open-chain bis-alkenylamide containing peptides, prepare

17 in is thermodynamically far less stable than open-chain but-2-ene-1,3-dione.

18 nitial cyclization product generated from an open-chain C(7) precursor, D-sedoheptulose 7-phosphate (

19 Neither thiocarbonates nor open chain carbonates served as substrate nor did a vari

20 the corresponding multiple beta-C-H arylated open-chain carboxamides (anti beta-acyloxy amides).

21 the formation of multiple beta-C-H arylated open-chain carboxamides from the Pd-catalyzed, bidentate

22 five- and six-membered ring compounds and in open-chain compounds the torsion angles vary considerabl

23 proportion of the oligoperoxides formed are open-chain compounds with end groups that suggest that c

24 icated that the phosphosugar is bound in the open-chain configuration.

25 enhanced approximately 5-fold relative to an open-chain congener.

26 opeptidic molecules (one macrocyclic and one open chain) containing an acridine unit have been prepar

27 ffinity and bio-availability compared to its open-chain counterpart.

28 served in the DAG lactone as compared to its open chain DAG counterpart.

29 ole 7 and subsequent macrocyclization of the open-chain derivatives 22-24 using HATU.

30 d temperatures were previously necessary for open-chain diene conjugation, additive-free HDA cycloadd

31 2]annulene by insertion of acetylene into an open-chain diiodo precursor under Sonogashira coupling c

32 ompared with (90)Y-hLL2 agents prepared with open-chain DTPA-type chelating agents.

33 After the open-chain energy minima of the 65-72 peptide were gener

34 rface, is 12.8 kcal/mol less stable than the open chain fluorobutyl cation 3.

35 a cis-enediol(ate) intermediate to yield the open chain form of the product.

36 e enzyme catalyzes ring opening to yield the open chain form of the substrate.

37 ma-OH-1,N(2)-propano-2'-deoxyguanosine to an open chain form, a structure that facilitates pairing wi

38 er one exists in solution exclusively in the open-chain form.

39 The binding site for the open chain glucitol residue extends to a subsite that is

40 s evoked patterns similar to those evoked by open-chained hydrocarbon odorants, a set of bicyclic com

41 ashion involving the initial formation of an open-chain imidoyl azide intermediate.

42 ion(s) in which the two reactive ends of the open-chain intermediate are located at short distances f

43 ivating the nitrile moiety and leading to an open-chain intermediate that subsequently cyclizes to pr

44 e with isoprene, which proceed stepwise with open chain intermediates, can account for the high regio

45 o exists in solution in equilibrium with its open-chain isomer 2-phenyl-2-(propan-2-ylidenehydrazono)

46 Two open-chain isomers, butadiynylthiol (8) and diethynyl su

47 icylaldehyde and p-tolualdehyde leads to the open-chain isomers, namely (2-hydroxybenzylidene)hydrazo

48 Open-chain N-Cbz-protected-peptidoyl benzotriazolides ar

49 Relative amounts of the open-chain oligomers so-formed suggest that undried buty

50 ed out in undried butyl acetate yield mainly open-chain oligoperoxides, confirming that propagating c

51 The reaction of open-chain or cyclic alpha-diketones with specific omega

52 e unbound host that helps to preorganize the open-chained peptide system.

53 These relatively simple, open-chained peptide systems interact with both chloride

54 nterconversion between a pentathiepin and an open-chain polysulfur ion intermediate from which a key

55 likely from the unimolecular collapse of the open-chain polysulfur ion.

56 ng an appropriate folded conformation of the open-chain precursor and reducing the energy barrier for

57 ternal template assisting the folding of the open-chain precursor in a proper conformation.

58 fect on the conformational equilibria of the open-chain precursors is very important.

59 selective for H(2)PO(4)(-) than the related open chain receptor.

60 ed C-H amination was examined with 18 chiral open-chain substrates, which bear a benzylic methylene g

61 nd on the alkaline side, ring closure of the open-chain sugar limits the rate.

62 e of cyclic hemiketal diastereomers, with an open-chain tautomer as a minor component.

63 solution, followed by the 4-hydroxycoumarin open-chain tautomer.

64 es the cysteine at position 198 to ligate an open chain tetrapyrrole covalently in a manner analogous

65 st of apoproteins covalently associated with open-chain tetrapyrrole chromophores.

66 version of ClFe(III)(meso-NH(2)-OEP) into an open-chain tetrapyrrole complex in which the original am

67 This open-chain tetrapyrrole complex itself is sensitive to a

68 gnaling, phytochromes need to associate with open-chain tetrapyrrole molecules as the chromophore.

69 me-like photosensory kinase possibly binding open-chain tetrapyrroles.

70 m nearly 0 degrees to 180 degrees and of the open chain tetrasilane Si(4)Me(10) (6) shows a clear con

71 ribe a computer algorithm to detect knots in open chains that is not sensitive to viewpoint and that

72 t of the dibasic N-terminal Lys of TP in the open-chain TP and its retroisomer was observed in certai

73 canonical-type strigolactones but feature an open-chain unit linking structurally diverse A-ring moie

74 It does this by reducing open chain xylose to xylitol, which is reoxidized to xyl