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1 ory mechanisms of healthy tissue continue to operate to a degree in tumors.

2 ype, this is unlikely to be the sole pathway operating to achieve adaptation.

3 into the mechanism by which AphA and AphB co-operate to activate the expression of tcpPH, we have pur

4 two yeast transcriptional regulators that co-operate to activate thioredoxin (TRX2) and thioredoxin r

5 ty implies that positive feedback mechanisms operate to allow commitment (i.e., the establishment of

6 ndent chromatin remodeling machines, that co-operate to assemble DNA and histone proteins into chroma

7 hypotheses about the types of processes that operate to assemble microbiomes over evolutionary time.

8 enoid valves), which are discretely computer-operated to automatically condition, calibrate and clean

9 Cellular defense systems operate to avoid molecular damage caused by ROS, but the

10 anglia support a basic attentional mechanism operating to bind input to output in the executive foreb

11 onize dE2F1-mediated activation, and they co-operate to block S phase progression in transgenic anima

12 ple integrated and often redundant responses operate to blunt the homeostatic threats generated by ex

13 Thus, multiple genetic programs operate to calibrate dendritic coverage, to coordinate t

14 l cells and suggest that the two proteins co-operate to carry out specific as yet unknown tasks betwe

15 understood, but the intracellular mechanisms operating to change the direction of axon outgrowth rema

16 he notable plasticity by which the replisome operates to circumvent obstacles in its path and may exp

17 perception, determined by visual experience, operates to compensate for large genetic differences in

18 laque phenotype; determining which mechanism operates to constrain plaque size may be more informativ

19 ented for how domain II of the IRES and NS5A operate to control host and viral translation during HCV

20 gest that an innate structural mechanism may operate to control non-specific association of membrane-

21 er which protein thiol/disulfide couples may operate to control physiologically relevant processes.

22 This novel mechanism of chaperone action may operate to control the activity of other important signa

23 Regulatory mechanisms must therefore operate to control the overall amount of Ca2+ that enter

24 A similar mechanism also operates to control expression of the genes in the Esche

25 es a similar 'clock-and-wavefront' mechanism operates to control somitogenesis; in all of them, somit

26 t promoters and the mechanisms by which TRF2 operates to control transcription remain elusive.

27 uses a mechanism that is distinct from that operating to control AU-rich mRNA stability in myeloid c

28 not the only way that this accessory protein operates to create a milieu conducive to robust virus gr

29 We hypothesize that the SIS RNAi pathway operates to defend the genome during sexual development.

30 our data show that the SIS RNAi pathway also operates to defend the genome via squelching transposon

31 mals, a relatively small number of receptors operate to detect signature molecules that herald infect

32 obins and leghemoglobin, proximal influences operate to determine fundamental dynamic and thermodynam

33 deling and nucleosome-depleted 'barriers' co-operate to determine the kinetics of nucleosome organiza

34 Our results illustrate how VHL and PBRM1 co-operate to drive renal transformation and uncover replic

35 ase our understanding of the mechanisms that operate to effect extracellular proteostasis, as this is

36 sms of mRNA and ribosome association with ER operate to enable an mRNA transcriptome-wide function fo

37 ynthase gene dusB is low, unusual mechanisms operate to enable robust translation of fis.

38 Once in the growth cone, further controls operate to enhance the retention or rejection, as approp

39 p62 may therefore operate to enhance TRIM5alpha-mediated retroviral restri

40 d cells determine stomatal aperture and must operate to ensure an appropriate balance between CO2 upt

41 c loci in nematodes and vertebrates, and may operate to ensure coordinate expression of these functio

42 ablish or maintain multiple constraints that operate to ensure coordination of events leading to chia

43 ults, we postulate that different mechanisms operate to ensure efficient transcription by RNA polymer

44 control system of the endoplasmic reticulum operate to ensure the proper folding of nascent TCRalpha

45 constraints imposed by an endogenous system operating to ensure that DNA acts in a cell-autonomous m

46 nd mCherry, reveal that different mechanisms operate to establish the excitation and emission maxima.

47 mplementation, possibly as incinerators were operating to EU-WID standards before the implementation

48 7 have fecal soiling, and 5 are too recently operated to evaluate.

49 ne possibility is that polar ejection forces operate to exert away-from-the-pole forces that could co

50 properties of the continents and the forces operating to exhume them over geologic time.

51 inct mechanisms flexibly and synergistically operate to facilitate perception and action.

52 the Vegf-Dll4/Notch feedback system normally operates to generate heterogeneity between endothelial c

53 ggest that associative substitution pathways operate to get the hydrocarbon substrate into, and out o

54 also show that two complementary mechanisms operate to implement a bias when two sets of priors are

55 volution is that natural selection primarily operates to improve replication fidelity, with the ultim

56 tational and population-level processes that operate to increase amounts of functionless DNA.

57 Multiple HSV genes can operate to increase virulence.

58 n intact ABA signaling pathway, and probably operates to increase ABA synthesis as part of a positive

59 ide sequence on either side of the linker co-operating to increase binding affinity.

60 e illustrates how pathogen detection systems operate to induce both membrane transport and signal tra

61 e Fas/CD95 cell death pathway which normally operates to induce apoptosis at the end of the terminal

62 Thus an auto-regulatory feedback mechanism operates to induce its own inhibitor SIRT3 by PGC-1beta.

63 t an independent-rapamycin-sensitive pathway operates to induce trophoblast motility, or that other,

64 s that the N- and C-termini of Kir6.2 may co-operate to influence channel closure by ATP.

65 FoxOs operate to inhibit mTORC1 signaling and cell survival in

66 rolling entry of cells into S phase, pRB can operate to inhibit S phase completion.

67 , indicating that a POSH-dependent mechanism operates to inhibit axon outgrowth in different types of

68 , 5 patients are wet, and 8 are too recently operated to judge.

69 ted by various signaling mechanisms that may operate to maintain appropriate levels of synaptic serot

70 Thus, these motives and emotions do not operate to maintain certain states of the self, as some

71 omosomal fragments, selection pressures must operate to maintain high EGFR copy number over multiple

72 ses, suggesting that multiple mechanisms may operate to maintain local adaptation.

73 ecause of multiple layers of regulation that operate to maintain metabolic steady state and because o

74 present our understanding of mechanisms that operate to maintain proteostasis in extracellular body f

75 ic and non-cell-autonomous actions of CTLA-4 operate to maintain T cell tolerance to a self antigen.

76 response network of pathways, both of which operate to maintain the integrity of the genome.

77 w certain keystone members of the microbiota operate to maintain the stability and functional adaptab

78 ction on the transcriptional output may have operated to maintain a similar pattern of Endo16 express

79 he photosystem II (PSII) repair cycle, which operates to maintain photosynthetic activity in the ligh

80 A network of mechanisms operates to maintain tolerance in the gut mucosa.

81 e "circuitry" connecting these factors could operate to match the expression of the lineage-committin

82 ed DNA binding functions of Hop2 and Mnd1 co-operate to mediate synaptic complex assembly, whereas ss

83 results indicate that an intact Xbp1 pathway operating to mitigate stress in the endoplasmic reticulu

84 , we hypothesized that a similar process may operate to modulate regulatory B cells (Breg).

85 Our results point to a mechanism operating to modulate the domain or duration of signalin

86 t least two alternative transport mechanisms operate to move peptides into the cell.

87 Do transcribed enzymes operate to obtain N from SOM?

88 Operating to obtain a high specific energy, however, res

89 velopment with morphogenetic mechanisms that operate to pattern an organ and the differentiation of i

90 tion of neural identity are separable events operating to pattern the rostral end of the early chick

91 ly play important roles in checkpoints which operate to permit cell survival following many forms of

92 We propose that such a mechanism may operate to potentiate adaptive immune responses against

93 Mechanisms that might operate to preserve the tight linkage of self-incompatib

94 malignant clones and that selection has been operating to preserve immunoglobulin structure.

95 DNA damage checkpoint pathways operate to prevent cell-cycle progression in response to

96 nts suggests that selective mechanism(s) may operate to prevent the appearance of these Abs during ac

97 uch needed insight into molecular mechanisms operating to prevent the loss of tolerance, particularly

98 idering how community effect signaling could operate to produce its observed effects, we construct an

99 s or the symptoms but at the mechanisms that operate to produce the symptoms.

100 laint of fatigue, other factors must also be operating to produce the full range of clinical symptoms

101 ion-coding striatal neuron, and show they co-operate to promote action selection in learning and comp

102 wo substrate-targeting sites in YopH that co-operate to promote epithelial cell detachment and bacter

103 ivity to early environmental influences that operate to promote social competency.

104 ediated effects and a viral superantigen are operating to promote the dramatic expansion and persiste

105 We speculate that this switch operates to protect insulin-and the beta-cell-from prote

106 oylation as a possible mechanism that may be operating to rapidly regulate synaptic efficacy.

107 at both nuclear import and export mechanisms operate to regulate cellular localization of an HMG box

108 th positive and negative feedback loops that operate to regulate different aspects of flower formatio

109 Here we discuss those mechanisms that operate to regulate effector immune responses.

110 site for Pbx-Prep/Meis (PM) heterodimers co-operate to regulate enhancer activity in r4.

111 Different mechanisms operate to regulate histone protein levels, and inductio

112 e signaling pathways in which RIPK4 and IRF6 operate to regulate keratinocyte differentiation are poo

113 ate the mechanisms by which Mdm2 and Mdmx co-operate to regulate p53 level and activity.

114 studies suggests that KSR1 and DCAF1 may co-operate to regulate schwannomas formation.

115 here that distinct regulatory miRNA networks operate to regulate Th2 cells in house dust mite-allergi

116 ts of the reciprocal control mechanisms that operate to regulate the activities of the two phyA signa

117 gnaling induced LGP2 expression wherein LGP2 operated to regulate death-receptor signaling and impart

118 Furthermore, this mechanism normally operates to regulate GSH biosynthesis in the cell, as GS

119 gesting the existence of parallel mechanisms operating to regulate SERT at serotonergic synapses.

120 Pyroptosis operates to remove the replication niche of intracellula

121 chronic photoinhibition, a PSII repair cycle operates to replace damaged PSII subunits with newly syn

122 st that several distinct signalling pathways operate to repress FPB1 and PCK1 transcription in the pr

123 has revealed that two regulatory regions co-operate to repress PAD1 expression, this being alleviate

124 data indicate that a negative feedback loop operates to repress transcription of the iscRSUA-hscBA-f

125 e showed that JAZ5 and JAZ10 specifically co-operate to restrict COR cytotoxicity and pathogen growth

126 ld requirement for Alx4 in a genetic program operating to restrict polarizing activity and Shh expres

127 proteins suggests that a distinct mechanism operates to retain resident plasma membrane proteins in

128 lly driven, and that a selection pressure is operating to retain type II NAD(P)H dehydrogenases in th

129 e roots use a "tipping point" mechanism that operates to reverse the asymmetric auxin flow at the mid

130 tissue sites and how tissue-related factors operate to shape immune cell fate and function.

131 ntly infected host, different mechanisms can operate to silence antiviral T cell responses; CD8 T cel

132 otor proteins kinesin-3 and dynein, which co-operate to support bi-directional motion of early endoso

133 zones (LGP), but the mechanisms by which it operates to sustain skeletal growth are not fully clear.

134 secretion (TTS) systems, which independently operate to target proteins to extracellular sites.

135 The inhibitory loop then operates to terminate outgrowth signals in the order obs

136 pressure UV light with and without TiO2 was operated to test the elimination efficiencies for 56 mic

137 t ES attached in the recirculation loop were operated to test whether the ES could control NH3 toxici

138 , different points in a drinking water plant operated to treat this source water, and in the associat

139 We propose that KIRs on memory T cells operate to uncouple effector functions by modifying the

140 t operational time frames when the plant was operating to when it was shut down, the plant was found

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