ライフサイエンスコーパス: operational tolerance

1 eral blood mononuclear cells correlates with operational tolerance.

2 plantation in relation to liver function and operational tolerance.

3 onor islet transplantation with induction of operational tolerance.

4 islets off all immunosuppression, suggesting operational tolerance.

5 loss of grafts after long periods of stable operational tolerance.

6 regulatory T (T(reg)) cells appear to foster operational tolerance.

7 transplantation medicine is the promotion of operational tolerance.

8 stigate the rationale for the development of operational tolerance across a major histocompatibility

9 Achieving operational tolerance after liver transplantation remain

10 velop a state of targeted immune quiescence (operational tolerance) against an HLA-mismatched graft,

11 intensive course of tacrolimus could induce operational tolerance and whether preoperative allopepti

12 inical end points included the durability of operational tolerance, and the incidence, timing, severi

13 (KLF6, BNC2, CYP1B1) to detect the state of operational tolerance by quantitative PCR.

14 This study provides the first evidence that operational tolerance can protect MHC nonhuman primate i

15 Patients with operational tolerance compared with patients without ope

16 sies from patients with spontaneous clinical operational tolerance (COT).

17 IS)-free state [also referred to as clinical operational tolerance (COT)] represents the ultimate goa

18 CD8+ donor bone marrow cells induced operational tolerance (defined as graft acceptance in th

19 The primary endpoint was the development of operational tolerance, defined as successful immunosuppr

20 imus, we have been able to induce a state of operational tolerance in a class I-disparate preclinical

21 have been described to be upregulated during operational tolerance in kidney allograft recipients.

22 We have previously reported operational tolerance in patients receiving human leukoc

23 To identify biomarkers of operational tolerance in pediatric and adult liver trans

24 ranscriptional profiles can be identified in operational tolerance in pediatric and adult recipients

25 possibility to create T(reg) cell-regulated operational tolerance in the absence of complete immune

26 The operational tolerance induction protocol combined peritr

27 nal tolerance compared with patients without operational tolerance initiated immunosuppression withdr

28 The concept of operational tolerance is more meaningful in the clinical

29 Operational tolerance is not a permanent state, and cont

30 hieved, but from the patient's point of view operational tolerance is the goal whereby, after a short

31 The term "operational tolerance" is used to indicate durable survi

32 ciated with long-term allograft survival and operational tolerance, memory B cells have been linked t

33 In this operational tolerance model, all immunosuppression was d

34 her than a deletional process underlies this operational tolerance model.

35 Increased serum HLA-G levels track with operational tolerance of liver grafts and support favora

36 le of Foxp3(+) regulatory T cells (Tregs) in operational tolerance remains elusive, as initial result

37 ver transplantation resulting in spontaneous operational tolerance (SOT), although the underlying mec

38 myeloid or lymphoid dendritic cells induces operational tolerance to a fully MHC-mismatched cardiac

39 to demonstrate the ability of DST to induce operational tolerance to cardiac allografts in large ani

40 active T reg cells during the development of operational tolerance to donor alloantigens in vivo.

41 Operational tolerance to HLA-A, B, and DR mismatched org

42 rapamycin treatment failed to promote early operational tolerance to LT.

43 how that it is possible to create a state of operational tolerance to lung allografts even in the pre

44 In utero inoculation led to operational tolerance to the donor's major histocompatib

45 with a mean age of 15 years; 13 patients had operational tolerance (TOL), with complete immunosuppres

46 Operational tolerance was achieved with only 4 days of d

47 d augmentation of expression was possible as operational tolerance was established to factor VIII wit

48 Operational tolerance was induced in hemiface allograft

49 ome kidney transplant recipients can achieve operational tolerance, we compared the expression profil

50 r histocompatibility complex peptide induces operational tolerance, whereas thymectomy abrogates this

51 or bone marrow (DBM) is shown here to induce operational tolerance with prolonged graft survival in t