ライフサイエンスコーパス: opium

1 citly use opiates, of whom 4 million use raw opium.

2 rising from compounds that are common in raw opium.

3 RNA aptamers that bind the opium alkaloid codeine were generated using an iterative

4 We have previously discovered the opium alkaloid noscapine as a microtubule interacting ag

5 We have previously identified the opium alkaloid noscapine as a microtubule interacting ag

6 rward method to determine the content of six opium alkaloids (morphine, codeine, thebaine, noscapine,

7 vine derivatives [buprenorphine] and natural opium alkaloids).

8 nificantly associated with comorbid cocaine, opium, and nicotine dependence.

9 Morphine, first characterized in opium from the poppy Papaver somniferum, is one of the s

10 Opium is one of the world's oldest drugs, and its deriva

11 An alkaloid from opium, noscapine, is used as an antitussive drug and has

12 Farming of opium poppies remains the sole source of these essential

13 Just over 100 years ago, opium poppies were still grown on the Cambridgeshire fen

14 ecarboxylase DNA fragment was generated from opium poppy (Papaver somniferum L.) genomic DNA by the P

15 The opium poppy (Papaver somniferum L.) is one of the oldest

16 ous end-joining genome repair, the 4'OMT2 in opium poppy (Papaver somniferum L.), a gene which regula

17 ne silencing, we show that FUL-like genes in opium poppy (Papaver somniferum) and California poppy (E

18 is a benzylisoquinoline alkaloid produced in opium poppy (Papaver somniferum) and other members of th

19 lation and functional characterization of an opium poppy (Papaver somniferum) cDNA encoding DBOX, a f

20 ally distinct N-methyltransferase (NMT) from opium poppy (Papaver somniferum) that primarily accepts

21 fic localization of morphine biosynthesis in opium poppy (Papaver somniferum).

22 compounds isolated from a single source, the opium poppy (Papaver somniferum).

23 Morphinan alkaloids from the opium poppy are used for pain relief.

24 transcript and metabolite profiles of eight opium poppy chemotypes revealed four cytochrome P-450s,

25 m cDNA libraries and latex extracts of eight opium poppy cultivars displaying different alkaloid prof

26 Stem cDNA libraries from each of the eight opium poppy cultivars were subjected to 454 pyrosequenci

27 The synthetic pathway of morphine in the opium poppy has been elucidated.

28 vel BIA biosynthetic and regulatory genes in opium poppy has been established based on the differenti

29 However, the biosynthesis of noscapine in opium poppy has not been established.

30 es were found during random sequencing of an opium poppy latex cDNA library.

31 SOMT transcripts were detected in all opium poppy organs but were most abundant in aerial orga

32 potential anticancer drug isolated from the opium poppy Papaver somniferum, and genes encoding enzym

33 aridine, the known morphine precursor in the opium poppy plant.

34 Opium poppy produces a wide variety of benzylisoquinolin

35 (RNMT) using virus-induced gene silencing in opium poppy resulted in a significant decrease in magnof

36 sanguinarine, and papaverine accumulation in opium poppy roots in support of DBOX as a multifunctiona

37 A query of translated opium poppy stem transcriptome databases using berberine

38 xpected, CYP82Y1 was abundantly expressed in opium poppy stems where noscapine accumulation is highes

39 Noscapine is an antitumor alkaloid from opium poppy that binds tubulin, arrests metaphase, and i

40 equence shares extensive identity with other opium poppy tyrosine/3,4-dihydroxyphenylalanine decarbox

41 as isolated that encodes a new member of the opium poppy tyrosine/3,4-dihydroxyphenylalanine decarbox

42 Morphine is an alkaloid from the opium poppy used to treat pain.

43 m the basal eudicot, Papaver somniferum (the opium poppy), and demonstrate a role for the gene in pat

44 s in a new model system, Papaver somniferum (opium poppy).

45 turase (PapsPDS) gene in Papaver somniferum (opium poppy).

46 The alkaloid-rich latex of the opium poppy, Papaver somniferum L., is valued as a sourc

47 In opium poppy, the antepenultimate and final steps in morp

48 Interestingly, in opium poppy, these genes also control flowering time and

49 endemically and uniquely in the latex of the opium poppy.

50 mitted step in the formation of noscapine in opium poppy.

51 lar localization of morphine biosynthesis in opium poppy.

52 guinarine and certain rhoeadine alkaloids in opium poppy.

53 mes in the biosynthesis of both alkaloids in opium poppy.

54 is in the roots and germinating seedlings of opium poppy.

55 t homology with the major latex protein from opium-poppy.

56 re should allow more efficient production of opium products and may be easily modified for large-scal

57 first detailed ion mobility study on seized opium samples.

58 ies of this instrument using four samples of opium seized by the Canada Border Services Agency (CBSA)

59 god of dreams could not have dreamt that his opium tincture would be both a gift and a burden to huma

60 eview to investigate the association between opium use and cancer incidence and mortality.

61 es that collect detailed data about lifetime opium use and control for a broad range of potential con

62 Opium use was associated with an increased risk of cance

63 , a benzylisoquinoline alkaloid derived from opium, was recently reported to exhibit activity against

64 ng the interaction of cocaine, nicotine, and opium with these variants.