ライフサイエンスコーパス: opposite face

1 ydrophobic cystine pairs plus two Ala on the opposite face.

2 rily conserved amino acids in Prp18 form the opposite face.

3 he glutamine side chains were arrayed on the opposite face.

4 t with departure of a leaving group from the opposite face.

5 esponsive ones (A300, I302, E303) lie on the opposite face.

6 merization followed by re-protonation on the opposite face.

7 ce while the polar residues aggregate on the opposite face.

8 wo sites to be at one end of the molecule on opposite faces.

9 decorated by four Ba(2+) ions on each of two opposite faces.

10 as polar/apolar residue pairs tend to occupy opposite faces.

11 On the opposite face, aligned along one helix, are exposed resi

12 Cell migration has two opposite faces: although necessary for physiological pro

13 mrR recognize the upstream promoter DNA from opposite faces and induce four significant kinks from th

14 of the helix, hydrophilic amino acids on the opposite face, and a number of basic amino acids surroun

15 e face is concomitant with delivery from the opposite face by the conjugate acid of the second enzymi

16 s of lipophilic ligand atoms are enclosed on opposite faces by lipophilic protein atoms, (2) neutral-

17 teraction with glycosaminoglycans, while the opposite face can bind fibronectin.

18 oss-strand cysteine residues that project on opposite faces close to the termini of the hairpin can s

19 matic and hydrophobic side-chains, while the opposite face contains a series of conserved charged or

20 splays hydrophobic leucine residues, and the opposite face displays hydrophilic lysine residues.

21 ctrostatic repulsion among phosphates on the opposite face drives bending toward the less negative su

22 the sites of Ig5 polysialylation are on the opposite face from the FN1 residues previously found to

23 two additional epitopes reside in F1 on the opposite face from the sialic acid-binding pocket.

24 of the molecule is strongly negative and the opposite face has a strong positive electrostatic field.

25 They are strikingly absent from the opposite face, implying that it is likely to face inward

26 ole for both the portal region of P2 and its opposite face in membrane interactions.

27 p/bulge segment of the RNA aptamer while the opposite face is capped by a stacked alignment of the A1

28 f the trimer is strikingly acidic, while the opposite face is more neutral.

29 N-terminal arm with the minor groove on the opposite face of DNA relative to the major groove that i

30 The other region, located on the opposite face of Doc1, is required for Doc1 to enhance s

31 Cys residue at position 27, which is on the opposite face of helix I, thereby indicating that the fa

32 ll likelihood because position 226 is on the opposite face of helix VII from position 228.

33 fication of Cys148, a residue located on the opposite face of RGS4, can disrupt RGS/Galpha interactio

34 is 19 of MGS and Lys 13 of TIM appear on the opposite face of the 2PG carboxylate plane, their relati

35 e catalytic base Asp 71 is positioned on the opposite face of the 2PG-carboxylate plane as Glu 165 of

36 e compounds likely bind within a site on the opposite face of the active site, and function as allost

37 s of nucleophilic attack by the amine on the opposite face of the alkene radical cation to the one sh

38 forms dimers through the AXXXG motif on the opposite face of the alpha-helix.

39 o other binding sites and that a loop on the opposite face of the ATPase rings stabilizes interaction

40 The best predicted site was on the opposite face of the beta sheet from the pan-HSP90 radic

41 s orients the four phthalimido groups on the opposite face of the catalyst.

42 ntation, beta-strands 1-3 and helix 2 on the opposite face of the catalytic domain contribute to memb

43 sepair with the internal C and stacks on the opposite face of the chromophore.

44 Val-203 interacts with the opposite face of the cofactor NAD+ from the alcohol subs

45 nd the C termini are located together on the opposite face of the dimer to facilitate membrane intera

46 DNA looping, movement of the operator to the opposite face of the DNA helix from the natural binding

47 ipulation places the IHF binding site on the opposite face of the DNA helix, directs the IHF-induced

48 A secondary surface resides on the opposite face of the domain and involves residues in hel

49 both cases, the catalytic domain lies on the opposite face of the enzyme from the SH2 and SH3 domains

50 g site, and forms a new interaction with the opposite face of the first Mcm2-7.

51 ODH (e.g., A77 1726) bind to a pocket on the opposite face of the flavin cofactor from dihydroorotate

52 Another ion-binding site on the opposite face of the G domain has been recently observed

53 acing the RcNtrC tandem binding sites on the opposite face of the helix (-113 bp) completely abolishe

54 e also identified a patch of residues on the opposite face of the helix and residues near both ends o

55 pid acyl chains and cationic residues on the opposite face of the helix interacting with the head gro

56 A residue on the opposite face of the helix only reacted with MTS reagent

57 e, and allow the nonpolar residues along the opposite face of the helix to remain immersed in the hyd

58 d exposes the hydrophobic amino acids on the opposite face of the helix.

59 cyclopropanation reaction takes place on the opposite face of the heterocycle, and the opposite enant

60 tes with the nucleophilic substituent on the opposite face of the ligand to the iron.

61 omain (cytodomain) regulates fusion from the opposite face of the membrane by an unknown mechanism.

62 Intercalation is on the opposite face of the modified S,R,S,RA6.T17 base pair as

63 Two arginine residues on the opposite face of the molecule (Arg-13 and Arg-32) and un

64 e ifnar1 binding site, was identified on the opposite face of the molecule.

65 e formed by the PGRP-specific segment on the opposite face of the molecule.

66 related by 2-fold symmetry, are found on the opposite face of the molecule.

67 loops and sites of glycosylation are on the opposite face of the NEC4 molecule from the site that in

68 F-AC is involved in RNA binding, whereas the opposite face of the NELF-AC subcomplex binds NELF-B.

69 in the opposite direction, and presents the opposite face of the nonsymmetrical, heterodimeric, IHF

70 hin the third helix of the EH domain, on the opposite face of the NPF-binding pocket, as being critic

71 ) results in preferential epoxidation of the opposite face of the olefin, which is followed by regios

72 n be explained by preferential attack on the opposite face of the oxocarbenium to the C2-H2 bond and

73 s pore, loop L3 was found to move toward the opposite face of the pore, resulting in decreasing the c

74 d phospholipid headgroup binding site on the opposite face of the PT1-Ca2+ complex as suggested by Ma

75 LCDR1; the HCDR3 makes interactions with the opposite face of the RBD from that of AZD8895.

76 C lacking bound substrate, donates H* to the opposite face of the resultant radical.

77 ly small chemical shift perturbations on the opposite face of the SH3 domain.

78 The opposite face of the somatomedin B-like domain interacts

79 FIIB or TFIIA suggests that BRF binds on the opposite face of the TBP-DNA complex from TFIIB and that

80 r with a large loop from each monomer on the opposite face of the tetramer (the alpha-face), which is

81 acent to the orthosteric binding site at the opposite face of Trp101.

82 itin (Ub) chain-specific binding site on the opposite face of UCH37 relative to the canonical S1 (cS1

83 egation of polar and hydrophobic residues to opposite faces of a predicted alpha-helical transmembran

84 with the two ATPases bound simultaneously to opposite faces of a single ClpP molecule were seen by el

85 nd a stem-loop binding protein (SLBP) target opposite faces of a unique highly conserved stem-loop RN

86 The two DAT epitopes were found on opposite faces of cellular and intracellular membranes,

87 derived from attack of the aza-anion on the opposite faces of conjugate system was obtained, startin

88 pushing out the T-bases of GTC's so that the opposite faces of each phenoxazone are stacked by the 3'

89 ubunit interface contains contributions from opposite faces of each subunit, designated + and -.

90 this study, we identify two basic patches on opposite faces of Ig3 that are critical for actin bindin

91 ly interact with RFXANK in vivo, bind to two opposite faces of its ankyrin repeats.

92 the 3'-sides of both G bases stacking on the opposite faces of its planar phenoxazone chromophore, a

93 bind to two distinct hydrophobic grooves on opposite faces of KIX.

94 e C1-C14 and C15-C10 bonds are formed on the opposite faces of the 14,15 double bond of the substrate

95 unusual interface, with Tfb3 binding on two opposite faces of the Arch.

96 hairpin, with the side chains projecting on opposite faces of the beta-sheet.

97 and two short alpha-helices which pack onto opposite faces of the beta-sheet.

98 es the addition of a hydride and a proton to opposite faces of the C horizontal lineC bond, has been

99 with axes that rotate by 90 degrees between opposite faces of the crystal.

100 ently, the bound BMP and PGD(2) direct their opposite faces of the cyclopentane moieties toward the n

101 ow the 2 S-domains to bind to these sites on opposite faces of the dimer.

102 perpendicular faces of the DNA, rather than opposite faces of the DNA as in Oct-1.

103 exclusive even though the two ligands occupy opposite faces of the DNA double helix.

104 ecognition sites for two Fur dimers bound to opposite faces of the DNA helix.

105 domain subunits bind nearly symmetrically to opposite faces of the DNA in a head-to-head fashion with

106 the SAP-1 monomer and SRF dimer are bound on opposite faces of the DNA, and that the DNA recognition

107 bithorax and Extradenticle homeodomains bind opposite faces of the DNA, with their DNA-recognition he

108 approximately 4/5 bp, placing nucleosomes on opposite faces of the DNA.

109 The two dimers clamp DNA from opposite faces of the double helix and form a topologica

110 two operator sequences overlap and occur on opposite faces of the double helix.

111 ng repeats to which PecS binds as a dimer on opposite faces of the duplex.

112 ely charged amino and guanidino groups along opposite faces of the elongated molecule, facilitating i

113 cture, pairs of inhibitory molecules bind to opposite faces of the enzyme tetramer.

114 f two distinct paxillin-binding sites on the opposite faces of the FAT domain.

115 tryptophan oxidation and oxygen reduction on opposite faces of the flavin ring.

116 xidation and oxygen reduction are located on opposite faces of the flavin ring.

117 ablish the localization of Ypt1 and Ypt31 to opposite faces of the Golgi: early and late, respectivel

118 ide chains of Lys331 and Pro417 pack against opposite faces of the guanine nucleotide base.

119 tative DNA-binding sites (sites I and II) on opposite faces of the H5 globular domain.

120 abilization from side-chain substitutions on opposite faces of the hairpin.

121 ur dimers interact with these sequences from opposite faces of the helix.

122 other basic) located near the C terminus on opposite faces of the helix.

123 the upstream and downstream contacts are on opposite faces of the helix.

124 and hydrophilic/charged residues situated on opposite faces of the helix.

125 ntacts with all of the above residues on the opposite faces of the IIIS6 helix, except for the putati

126 targeting and transforming activities lie on opposite faces of the MCV sT molecule and can be genetic

127 BlaI and, probably, MecI dimers bind to opposite faces of the mec DNA double helix in an up-and-

128 r contains two ubiquitin binding surfaces on opposite faces of the molecule that cannot bind simultan

129 unction, important 2'-hydroxyl groups lie on opposite faces of the molecule, defining distinct loci f

130 ement regulatory activities of CD55 occur on opposite faces of the molecule.

131 d the carbohydrate-binding sites situated on opposite faces of the molecule.

132 een 1.8 and 1.9 A normal to the centroids of opposite faces of the near coplanar of the 2-butene comp

133 nomers bind to two identical surfaces on the opposite faces of the neuroligin-1 dimer to form a heter

134 es the geometry of key catalytic residues on opposite faces of the NNIBP.

135 produces two sites of increased digestion on opposite faces of the nucleosome and decreased digestion

136 he imidazoline substituents R(1) and R(2) on opposite faces of the palladium square plane.

137 at the 3'-sides of both G-bases stack on the opposite faces of the phenoxazone plane.

138 e C(60) and BTMPA units are bound axially to opposite faces of the porphyrin plane via covalent and c

139 red residues map to two different regions on opposite faces of the protein, suggesting that the inter

140 ignals on mu2 and mu4, which were located on opposite faces of the proteins.

141 s the same face of the proximal double bond, opposite faces of the resulting enolate anion intermedia

142 ine distinct protein interaction surfaces on opposite faces of the RHD.

143 directing groups can promote epoxidation on opposite faces of the ring scaffold, evidence of competi

144 stinct groups that form discrete clusters on opposite faces of the S1 domain.

145 he pairs form an ordered monolayer, exposing opposite faces of the same molecule.

146 nd acoustic properties can be implemented on opposite faces of the same wafer, markedly enhancing the

147 served aspartate residue that are located on opposite faces of the sugar ring.

148 The K2hPg residues occupied opposite faces of this helix, an arrangement that minimi

149 l phosphonates: reduction proceeded from the opposite face relative to that observed in the analogous

150 ive partners, Bag6 wraps around TRC35 on the opposite face relative to the Get4-5 interface.

151 genesis analysis revealed that there are two opposite faces that are involved in self-association and

152 On the opposite face, the N-terminal gamma chains fold into a s

153 uding a potential new regulatory site on the opposite face to that involved in the binding of rapamyc

154 ly with CRP, and is distinct from and on the opposite face to the proposed determinant for alphaCTD-C

155 principle of phenoxazone ring requiring its opposite faces to be stacked by the 3'-sides of two G ba

156 en" conformer (where the two guanines are on opposite faces) to the "closed" conformer (where the two

157 In contrast, the opposite face tolerated virtually all possible substitut

158 the active site of the molecule, whereas the opposite face was predominantly affected by the mutation

159 and MPB83 contain two functional surfaces on opposite faces, which are probably involved in binding t

160 ha(3)) on one face and helix alpha(2) on the opposite face with a characteristic Rossmann fold compri