ライフサイエンスコーパス: optic chiasm

1 aplastic haemangiopericytoma compressing the optic chiasm.

2 mbryonic brain during formation of the mouse optic chiasm.

3 of cell groups that lie within the nerve and optic chiasm.

4 rve outgrowth, including path-finding at the optic chiasm.

5 commissure, which is located adjacent to the optic chiasm.

6 olfactory tract, mammillothalamic tract, or optic chiasm.

7 halmia and hypoplasia of the optic nerve and optic chiasm.

8 l axon divergence associated with the albino optic chiasm.

9 days after birth (P24) at the centre of the optic chiasm.

10 equired for efficient RGC decussation at the optic chiasm.

11 athfinding of the ganglion cell axons at the optic chiasm.

12 ultimately affects axonal growth through the optic chiasm.

13 s a missorting of RGC axons as they exit the optic chiasm.

14 ome biogenesis and axonal growth through the optic chiasm.

15 lmic disorders affecting the optic nerve and optic chiasm.

16 tes, and anomalous axonal pathfinding at the optic chiasm.

17 axial planes 1-mm thick and parallel to the optic chiasm.

18 with the RGCs themselves, most likely at the optic chiasm.

19 nas still project axons to the brain via the optic chiasm.

20 ltered in the developing Foxg1-/- retina and optic chiasm.

21 Foxg1 is also expressed at the optic chiasm.

22 r contralateral targets, thereby forming the optic chiasm.

23 ral diencephalon during the formation of the optic chiasm.

24 ws from the ventrotemporal retina toward the optic chiasm.

25 ons either cross or avoid the midline at the optic chiasm.

26 ial manifestation of disorders involving the optic chiasm.

27 ons either cross or avoid the midline at the optic chiasm.

28 A/OPCs isolated from cortex, optic nerve and optic chiasm.

29 on for retinal axon growth in the developing optic chiasm.

30 pond by making axonal guidance errors at the optic chiasm.

31 lion cells with uncrossed projections at the optic chiasm.

32 knockout mice and analyzed their retinas and optic chiasms.

33 ecision to cross or avoid the midline at the optic chiasm, a critical guidance maneuver that establis

34 Thus, within the optic chiasm, a sequence of positional transformations o

35 e retina and in the region of the developing optic chiasm, a ventral midline structure in which retin

36 erns of heparan sulfation on RGCs and at the optic chiasm and (2) this differential sulfation directs

37 estigated with reference to disorders of the optic chiasm and anophthalmia (absence of the eyes).

38 s RGC axons exhibited normal crossing at the optic chiasm and fasciculation of the optic nerve.

39 axon guidance factors, and the absence of an optic chiasm and forebrain commissures.

40 their predetermined crossing pattern in the optic chiasm and grew to the ipsilateral LGN.

41 rocesses, such as pathfinding of RGCs at the optic chiasm and hippocampal long-term potentiation and

42 (RGC) fibers affects the organization of the optic chiasm and lateral geniculate nuclei (LGN) in huma

43 of the optic nerves, chiasm and tracts, and optic chiasm and LGN volume compared with controls (P <

44 directly control RGC axon divergence at the optic chiasm and may additionally function as a general

45 etain-->and markedly reduced the size of the optic chiasm and optic nerves.

46 llele reduced axonal midline crossing at the optic chiasm and optic tract fasciculation.

47 Between E30 and E35, the optic chiasm and optic tract remain acellular, but the l

48 The optic chiasm and splenium of the corpus callosum were tr

49 It is dorsally bounded by the optic chiasm and the alar hypothalamus, and caudally by

50 We have examined the optic chiasm and the retina in albino and normally pigme

51 lateral and contralateral projections at the optic chiasm and the subsequent segregation of retinal i

52 Axon organization in the optic chiasm and tract and RGC growth cone morphologies

53 , the body of the optic stalk and nerve, the optic chiasm and ventral diencephalon, and the anterior

54 sal and temporal retinal fibers cross at the optic chiasm, and (2) ocular dominance columns normally

55 ovided identical tracing of the optic nerve, optic chiasm, and optic tracts to the level of the later

56 ptic stalk, cross the ventral midline at the optic chiasm, and terminate in the optic tectum of the z

57 spinal cord, the hindbrain and midbrain, the optic chiasm, and the median eminence in the forebrain.

58 n in significant numbers and fail to form an optic chiasm; and (4) axons in multiple commissural trac

59 n, the mechanisms for axon divergence in the optic chiasm are discussed in the context of other popul

60 tricular and subventricular zones and in the optic chiasm, areas that are rich in oligodendrocyte (OL

61 in determining the relative position of the optic chiasm at the ventral midline of the developing hy

62 At the optic chiasm, axons from either eye meet and decide whet

63 e, loss of axonal staining progressed to the optic chiasm by 7 days and remained undetectable at 2 we

64 hen GAP-43-deficient axons are cultured with optic chiasm, cortical, or dorsal midbrain cells.

65 e and in the pattern of decussation at their optic chiasm, demonstrating that a melanin-related agent

66 nal ganglion cell (RGC) axons at the midline optic chiasm determines whether RGCs project to ipsilate

67 ription factor known for its role in eye and optic chiasm development, causes the rostral oral ectode

68 Here, we review recent findings on optic chiasm development, highlighting the specific tran

69 Electrical stimulation of the optic chiasm elicits reduced calcium transients and impa

70 ), and cross the diencephalon midline at the optic chiasm en route to their brain targets.

71 e on the ventral surface of the brain at the optic chiasm for sorting into the optic tracts.

72 nal axon growth and/or reorganization during optic chiasm formation.

73 he developing ventral diencephalon where the optic chiasm forms.

74 e site in the ventral diencephalon where the optic chiasm forms.

75 is absent from the ventral midline where the optic chiasm forms.

76 the midline, thus forming the bodily crossed optic chiasm found in fish.

77 Optic nerve from EAE and optic chiasm from MS also showed decreased cholesterol s

78 al axons and the cellular composition of the optic chiasm in albino mice are similar to those of norm

79 Vema is localized to the floor plate and the optic chiasm, intermediate targets located at the ventra

80 nal ganglion cell (RGC) axon growth from the optic chiasm into the optic tract are unknown.

81 GC) axons fail to progress normally from the optic chiasm into the optic tracts.

82 The mouse optic chiasm is a model for axon guidance at the midline

83 The optic chiasm is an important choice point at which retin

84 Interestingly, expression in the optic chiasm is high at postnatal day 6, but decreases w

85 In affected animals, the optic chiasm is missing, and each retina projects entire

86 iculate nucleus (dLGN), when crossing at the optic chiasm midline is altered.

87 axons away from its ligand, ephrinB2, at the optic chiasm midline, and a transcription factor Zic2, t

88 cell (RGC) axons from nasal retina cross the optic chiasm midline, whereas temporal retina axons do n

89 o regulate RGC axon repulsion by cues at the optic chiasm midline.

90 at directs the ipsilateral projection at the optic chiasm, misrouted RGCs target the appropriate reti

91 ation associated with axonal behavior at the optic chiasm must affect ganglion cells in a cell-extrin

92 in the diencephalic preoptic area, where the optic chiasm normally forms.

93 (WM) tracts and in the corpus callosum (CC), optic chiasm (Och), and internal capsule.

94 In the optic chiasm of mammals, axons either cross the midline

95 The optic chiasm of marsupials differs from that of the euth

96 Brn3b(-/-) mice but missing were entirely in optic chiasms of Brn3b/Brn3c double knockout mice, sugge

97 Retinal axons cross the neuraxis to form the optic chiasm on the hypothalamus in a position defined b

98 lved both in determining the position of the optic chiasm on the ventral diencephalon (presumptive hy

99 ) project axons along the optic nerve to the optic chiasm on the ventral surface of the hypothalamus.

100 The core is located above the optic chiasm, receives primary and secondary visual affe

101 on of Vema in the developing spinal cord and optic chiasm resembles the expression patterns of a vari

102 At the optic chiasm, retinal ganglion cell (RGC) axons make the

103 At the optic chiasm, retinal ganglion cell axons from each eye

104 At the optic chiasm, retinal ganglion cells (RGCs) project ipsi

105 We found that glutamate agonists and optic chiasm stimulation inhibit serotonergic phase adva

106 ents this increase, abolishes glutamate- and optic chiasm stimulation-induced phase delays of the SCN

107 al hypothalamus, and in a site dorsal to the optic chiasm that included the suprachiasmatic nucleus.

108 nd therapeutic interventions that damage the optic chiasm, the pituitary stalk and the hypothalamic a

109 The second site is the optic chiasm, the site of retinal axon divergence.

110 abnormal retinal decussation patterns at the optic chiasm: their uncrossed projections are smaller an

111 ficient mice initially fail to grow from the optic chiasm to form optic tracts and are delayed tempor

112 ganglion cell (RGC) axons diverge within the optic chiasm to project to opposite sides of the brain.

113 whether to cross or avoid the midline at the optic chiasm to project to targets on both sides of the

114 s with ephrin-B2 on radial glia cells at the optic chiasm to repulse VT axons away from the midline a

115 agonists, and electrical stimulation of the optic chiasm to SCN brain slices to determine the effect

116 of retinal ganglion cell (RGC) axons at the optic chiasm to the appropriate hemisphere, a pattern cr

117 ding from the area immediately caudal to the optic chiasm to the level of the posterior hypothalamus.

118 sion that retinal ganglion cells make at the optic chiasm, to either cross or avoid the midline.

119 Morphologic analysis of the optic chiasm was based on manual measurement of regions

120 ct retinal axon growth and divergence at the optic chiasm, we cocultured mouse retinal and chiasm exp

121 Ipsilateral and misrouted projections at the optic chiasm were overproduced in Brn3b(-/-) mice but mi

122 ls, some axons from each retina cross at the optic chiasm, whereas others do not.

123 eview, we compare guidance mechanisms at the optic chiasm with those in other midline models and high

124 rgence of retinal ganglion cell axons at the optic chiasm, with strictly controlled numbers projectin

125 nerve regeneration, with axons reaching the optic chiasm within 3 wk.

126 embryos deficient in GAP-43 have an enlarged optic chiasm within which RGC axons were reportedly stal