ライフサイエンスコーパス: optic stalk

1 ng neural retina and ventricular zone of the optic stalk.

2 of the PAX6 domain from the retina into the optic stalk.

3 c epithelium and move toward and through the optic stalk.

4 th highest levels of expression in the nasal optic stalk.

5 as in wild type, but are unable to enter the optic stalk.

6 ure as it forms in the ventral optic cup and optic stalk.

7 at the optic disc through patterning of the optic stalk.

8 neural crest cells to accumulate around the optic stalk, a source of the ligand Pdgfaa.

9 As Pitx2 is not expressed in the optic stalk, an essential function of PITX2 protein in n

10 f the vertebrate optic vesicle into proximal/optic stalk and distal/neural retina involves midline-de

11 The RBG originate in the optic stalk and have been thought to migrate into the ey

12 t8b expression upregulated in the Foxg1(-/-) optic stalk and hypothesized that, similar to what is ob

13 ived factor-1 (SDF1) is expressed within the optic stalk and its receptor CXCR4 is expressed in retin

14 d fissure of the optic disk, the body of the optic stalk and nerve, the optic chiasm and ventral dien

15 ression was also noted within the developing optic stalk and optic disk.

16 the Pax2+ cells in the embryonic retina and optic stalk and the initial misrouting of the ganglion c

17 e that arise from precursors in the eye-disc/optic stalk and those that arise from precursors in the

18 ) signaling ventralize the eye, by expanding optic stalk and ventral retina, and repressing dorsal re

19 ing domains encompassing the ventral retina, optic stalks and preoptic area.

20 optic cup, including the pigment epithelium, optic stalk, and ciliary body.

21 ystem, slit2 is expressed in the eye, in the optic stalk, and in the ventral diencephalon.

22 the ventral portion of the retina and in the optic stalk, and the ligands and binding proteins locali

23 nal pigment epithelium (RPE), the optic disk/optic stalk, and the pecten oculi.

24 oma leading to the misdifferentiation of the optic stalk as retina, which becomes continuous with the

25 A frequently observed defect is an optic stalk coloboma leading to the misdifferentiation o

26 During normal development, the optic stalks constrict, decreasing in width and are grad

27 ganglion cell axons exit the eye, enter the optic stalk, cross the ventral midline at the optic chia

28 pression of PKI partially rescues somite and optic stalk defects in no tail and cyclops mutants that

29 ndependent of the effects of Hh signaling on optic stalk development.

30 The defects in optic-stalk differentiation correlate with reduced sonic

31 ut later their axons are unable to enter the optic stalk en route to the brain and continue to projec

32 cts in optic stalk morphogenesis whereby the optic stalk extends into the retina and impedes the late

33 to medial instead of bilateral induction of optic stalks followed by a partial fusion of the eyes at

34 mus, and are implicated in the regulation of optic stalk formation, whereas loss of Fgf3 alone result

35 inding and show that Shh acts to pattern the optic stalk in zebrafish but does not guide RGC axons in

36 entral identities, neural retina and ventral optic stalk is also compromised.

37 tructure arising from the optic vesicle, the optic stalk, is missing and is replaced by an expanded r

38 elium-like tissue, and ectopic expression of optic stalk markers in the region of the ventral retina

39 Colobomas result from defects in optic stalk morphogenesis whereby the optic stalk extend

40 lial cells that line the choroid fissure and optic stalk/nerve to its junction with the optic tract.

41 ddition, we show that the attenuation of the optic stalk occurs in parallel with ganglion cell differ

42 ntify upregulated expression of Wnt8b in the optic stalk of Foxg1(-/-) mutants before OF closure init

43 The diencephalon-derived optic stalk (OS) and neural retina are also patterned in

44 igate across the retina, exit the eye to the optic stalk (OS), and cross the diencephalon midline at

45 The optic stalk represents the ventral-most region of the ea

46 (3) A few glia close to the entry of the optic stalk suffice to guide the axons into the stalk, s

47 e and abnormal differentiation of the dorsal optic stalk; the development of proximo-ventral identiti

48 While in the optic stalk, they grow immediately adjacent to cells exp

49 in the absence of photoreceptor axons in the optic stalk; they also migrate to ectopic patches of dif

50 naling from the pharyngeal arch endoderm and optic stalk to Cxcr4a expressing CNCCs is important for

51 ganglion cell axons within the retina to the optic stalk to exit the retina.

52 s on Wnt8b suppression by Foxg1 in the nasal optic stalk to maintain balanced apoptosis and Pax2 expr

53 x2+ cells in the posterior optic cup and the optic stalk undergo abnormal morphogenetic movements and

54 mic high RA levels cause an expansion in the optic stalk with an increased cell content and a patent