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1 ule real-time sequencing and high-resolution optical mapping.
2 subtracted) during AF in vivo and in ex vivo optical mapping.
3 tle fine-scale Ca(2+) alternans, captured by optical mapping.
4 ce alignment, with modifications specific to optical mapping.
5 ective myocardial conduction was detected by optical mapping.
6 ysis was performed on each preparation after optical mapping.
7 icular conduction velocity, as determined by optical mapping.
8  mice using high-resolution, dual-wavelength optical mapping.
9 typic sequenced strain by using the tools of optical mapping.
10 acteristics of the PVs using high-resolution optical mapping.
11 tential plateau, and DeltaVm was measured by optical mapping.
12  strain 2.4.1 were constructed using shotgun optical mapping.
13 ships were assessed using immunostaining and optical mapping.
14 ivation spread recorded simultaneously using optical mapping.
15  which utilize molecular fixation, including optical mapping.
16 fingerprinting, radiation hybrid mapping and optical mapping.
17 nesthetized Thy1-GCaMP mice using wide-field optical mapping.
18 al locations on the molecules generated from optical mapping.
19 recording depolarization in the scar through optical mapping.
20                 Activation was recorded with optical mapping.
21                   We addressed this gap with Optical Mapping, a high-throughput, high-resolution sing
22 ip system has drawn from critical aspects of Optical Mapping, a single-molecule system that enables t
23                        Here, we describe how optical mapping, a single-molecule system, was used to i
24 In this study, we present the application of optical mapping, a single-molecule, whole-genome analysi
25 hromosome 2 DNA as the starting material for optical mapping, a system for making ordered restriction
26 s were removed during the integration of the optical mapping and chromosome conformation capture data
27         Despite their technical differences, optical mapping and chromosome conformation capture perf
28 se assemblies, we generated BioNano Genomics optical mapping and Dovetail Genomics chromosome conform
29                               Finally, using optical mapping and electrophysiological analyses, we pr
30 c animals and incorporating information from optical mapping and fiber-FISH.
31                                 Here we used optical mapping and Fourier analysis to determine the di
32 ethod relieves a long-standing limitation of optical mapping and has potential to enhance new studies
33                          We applied biatrial optical mapping and immunoblot mapping of various atrial
34                                              Optical mapping and immunohistochemistry indicate that p
35 Electrophysiological effects were studied by optical mapping and patch-clamping.
36 in the intact non-failing rabbit heart using optical mapping and pharmacological manipulation of RyRs
37 e isolated rabbit heart experimentally using optical mapping and superconducting quantum interference
38                            Using ratiometric optical mapping and video microscopy, we discovered that
39 ent Na(+)-channel block mathematical models, optical mapping, and action potential recording were use
40 able by pulsed-field gel electrophoresis and optical mapping, and harbored a novel pmrC1A1B allele.
41 d Pitx2c mRNA by electrophysiological study, optical mapping, and patch clamp studies.
42                                  Using a new optical mapping approach, we measured action potentials
43  study, using next-generation sequencing and optical mapping approaches, a 24.1-Mb complete genome of
44 natal rat ventricular myocytes and performed optical mapping at high temporal and spatial resolution.
45                                           In optical mapping, at 4 mM [K(+)](o), 17 null hearts showe
46                                Using in vivo optical mapping/calcium imaging, we determined that the
47                               We discuss how optical mapping can be used as a validation tool for gen
48         Given the rapid spread of the use of optical mapping, careful evaluation must be made in term
49           We used epicardial and endocardial optical mapping, chemical subendocardial ablation with L
50                                   Subsequent optical mapping confirmed a DF gradient from posterior L
51                                              Optical mapping confirmed that treatment with each compo
52             We generated and used stimulated optical mapping data for loblolly pine and F.tularensis
53 loblolly pine and F.tularensis and used real optical mapping data for rice and budgerigar.
54              Analysis of lacZ expression and optical mapping data highlight important differences bet
55                                  Analysis of optical mapping data reveals that VF excitation frequenc
56                                          The optical mapping data were in good agreement with theory.
57  from the sequence data were compared to the optical mapping data, and good correspondence was found.
58                               Using the real optical mapping data, we correctly identified 75% of ext
59 akpoints using paired-end sequence reads and optical mapping data.
60 n source computational methods for analyzing optical mapping data.
61 re few publicly available tools for aligning optical mapping datasets.
62                                              Optical mapping demonstrated that current delivered with
63 sing CLC Genomics Workbench read mapping and Optical mapping developed by OpGen.
64      Simultaneous endocardial and epicardial optical mapping (di-4-ANEPPS) was performed in isolated,
65                                              Optical mapping (Di-4-ANEPPS, 300 frames/sec) of the pos
66       In preparations with z(0) <700 microm, optical mapping during epicardial stimulation revealed u
67                                              Optical mapping during VF showed that activity often beg
68                              High-resolution optical mapping employing seven enzymes places these clo
69                                              Optical mapping enabled spatial characterization of exci
70 assive number of individual DNA molecules by optical mapping enables assembly of physical maps spanni
71                                              Optical mapping experiments allow investigators to view
72    METHODS AND Biochemical, patch clamp, and optical mapping experiments demonstrate that PKP2 associ
73                                     Finally, optical mapping experiments in AnkG-silenced cells demon
74                                 We performed optical mapping experiments in isolated Langendorff-perf
75       Here, we simulate dual voltage-calcium optical mapping experiments using a monodomain-Luo-Rudy
76                                              Optical mapping experiments were performed on Langendorf
77                           In simulations and optical mapping experiments, virtual PentaRay recordings
78 combination of microelectrode recordings and optical mapping experiments.
79 maging and enriched the model with data from optical mapping experiments.
80  and by abolishing contraction, also prevent optical mapping from being used to study coupling betwee
81                                              Optical mapping has become an indispensible tool for stu
82                                      Cardiac optical mapping has proven to be a powerful technology f
83         Recent advances in the automation of optical mapping have enabled us to map a set of 16 BAC c
84  microelectrode recordings and more recently optical mapping have ushered in new periods of significa
85 estion, we conducted simultaneous voltage/Ca optical mapping in atrial tissue and one-/two-dimensiona
86 mon understanding of the basic principles of optical mapping in complex 3D anatomic structures.
87                            METHODS AND Using optical mapping in isolated perfused canine atrial prepa
88 rther confirmed by electric measurements and optical mapping in Langendorff-perfused hearts.
89  propagation was assessed by high-resolution optical mapping in monolayers of neonatal rat ventricula
90                  By allowing high-resolution optical mapping in the absence of electromechanical unco
91 iefly look into the possible future roles of optical mapping in the development of regenerative cardi
92         A good example of this is the use of optical mapping in the sinoatrial node (SAN): when micro
93                                              Optical mapping is a new tool that creates a high-resolu
94                                              Optical mapping is a technique for capturing fluorescent
95                                              Optical mapping is an accessible and relatively mature t
96                                              Optical mapping is an emergent technology for genomic an
97 r study that may be used, until such time as optical mapping is clinically feasible, to improve mecha
98 lysis which may facilitate the automation of optical mapping is presented.
99      An important limitation of conventional optical mapping is that contraction is usually arrested
100                                    Panoramic optical mapping is the primary method for imaging electr
101                                  Traditional optical mapping lacks the spatial resolution to assess c
102  but MI differences are amplified by current optical mapping methods.
103                                           In optical mapping, molecules are elongated and fixed onto
104 gated using a combination of high-resolution optical mapping (n = 5) and extracellular bipolar and in
105  underlying PV tachycardias was confirmed by optical mapping (n = 5).
106                     By using high-resolution optical mapping, numerical simulations and metaanalysis
107                                      We used optical mapping of action potentials and ratiometric cal
108                                     Notably, optical mapping of action potentials in atrial fibrillat
109          Here, we make progress by combining optical mapping of action potentials with concurrent act
110                                              Optical mapping of arrhythmias and defibrillation provid
111                                              Optical mapping of Ca(2+) transients revealed that rat A
112 t this hypothesis, we performed simultaneous optical mapping of Ca(i) and membrane potential (V(m)) i
113                                              Optical mapping of cardiac electrical activity using a v
114                                  So far, the optical mapping of cardiac electrical signals using volt
115 he excitation and emission of photons during optical mapping of cardiac tissue.
116                                              Optical mapping of chimeric hearts by use of voltage-sen
117                                              Optical mapping of coronary-perfused atria (n=24) reveal
118                             Novel intramural optical mapping of coronary-perfused right atrial prepar
119                                              Optical mapping of cytosolic calcium transients in intac
120                                              Optical mapping of DeltaSIV hearts revealed that ventric
121  diagnostic applications, DNA sequencing and optical mapping of epigenetic markers.
122              While over the last two decades optical mapping of excitation (voltage and calcium dynam
123                                        Thus, optical mapping of genetically engineered mice may help
124                                              Optical mapping of HFpEF hearts demonstrated prolonged a
125                                              Optical mapping of intact cardiac tissue reveals that, i
126 or improved interpretation of the results of optical mapping of intact heart preparations.
127                                              Optical mapping of intracellular Ca (Ca(i)) and voltage
128                                 Simultaneous optical mapping of intracellular Ca(2+) and membrane pot
129                                  At 4 weeks, optical mapping of intracellular Ca2+ and ROS was perfor
130      In vitro, high-resolution near-infrared optical mapping of intramural SAN activation was perform
131  neonatal cell pairs from mutant hearts, and optical mapping of isolated-perfused hearts with voltage
132                 Simultaneous voltage-calcium optical mapping of Langendorff-perfused SHR hearts revea
133                                              Optical mapping of membrane voltage (V(m)) and intracell
134 y ganglia in vivo, opening the door to rapid optical mapping of neuronal excitability.
135 s of AF drivers in a 2-dimensional model and optical mapping of ovine atrial scar-related AF.
136                                              Optical mapping of perfused hearts confirmed slowed cond
137                                              Optical mapping of the epicardial electrical activation
138 ion potential duration using high-resolution optical mapping of the epicardial surface in 8 isolated,
139                                              Optical mapping of the epicardial surface in ventricles
140                                     Detailed optical mapping of the epicardial surface of guinea pig
141                                              Optical mapping of the first extrabeat with a coupling i
142 ultaneous voltage and intracellular Ca(+)(2) optical mapping of the left ventricular epicardial surfa
143        Conduction velocity measurements from optical mapping of the RBB revealed slow conduction in C
144                         We used simultaneous optical mapping of the right and left atria (RA and LA)
145 cts of ISO on LQT1 and LQT2 were verified by optical mapping of the whole heart, suggesting that ISO-
146                                 Simultaneous optical mapping of transmembrane potential and Ca(2+) tr
147              To validate this model, we used optical mapping of transmembrane potential and calcium t
148                                              Optical mapping of transmembrane potential and intracell
149 ocity, measured by multisite high-resolution optical mapping of transmembrane potential in strands of
150 ping ventricular myocardium using high-speed optical mapping of transmembrane potentials and calcium
151 formed, and a 4-cm2 area of the PV underwent optical mapping of transmembrane voltage to obtain 256 s
152                     In addition, comparative optical mapping of two other inbred maize lines revealed
153                                              Optical mapping of uniformly Kir2.1 gene-modified monola
154                                              Optical mapping of V(m) and Ca(i) in paced rabbit hearts
155                                      We used optical mapping of V(m) in patterned cultures of neonata
156                                 Simultaneous optical mapping of Vm (with RH237) and [Ca(2+)]SR (with
157                                 Simultaneous optical mapping of voltage and [Ca(2+)]i in CPVT hearts
158  Programmed electric stimulation ex vivo and optical mapping of voltage transients indicated that pep
159 nformation from the shape of the upstroke in optical mapping recordings.
160 egmentation and tracking of cardiac waves in optical mapping recordings.
161                                              Optical mapping revealed a loss of the normal elliptical
162                                              Optical mapping revealed cardiac refractoriness with los
163 solated, Langendorff-perfused rabbit hearts, optical mapping revealed that dofetilide-induced arrhyth
164                                              Optical mapping revealed that selectively the transverse
165 ifferences similar to variations in I(Ca,L); optical mapping revealed that the earliest EADs fired at
166 and long-read sequencing in conjunction with optical mapping, revealed a compact genome of approximat
167 First, we explore key components of a modern optical mapping set-up, focusing on: (1) new camera tech
168                                              Optical mapping showed increased activation in the borde
169                              High-resolution optical mapping showed that epicardial wavefront expansi
170                                              Optical mapping showed that this effect also applied to
171 phasic action potentials and to conventional optical mapping signals.
172 f electrical shocks within the heart, recent optical mapping studies have revealed two major discrepa
173                                              Optical mapping studies have suggested that intracellula
174                                              Optical mapping studies in mice demonstrate that ANP spe
175                       We then look at recent optical mapping studies in single cells, cardiomyocyte m
176                                       Recent optical mapping studies of cardiac tissue suggest that m
177                                    Moreover, optical mapping studies of embryonic hearts demonstrate
178                                 We performed optical mapping studies of VF in isolated swine right ve
179                                              Optical mapping studies showed that during rapid ventric
180 zation of the large-insert clones, e.g., for optical mapping studies.
181                                              Optical mapping surfaces have been shown to be compatibl
182                                          The Optical Mapping System discovers structural variants and
183                                          The optical mapping system reported here is based on our phy
184                                  A multisite optical mapping system was used to obtain 17 or 25 micro
185 tin using either a confocal microscope or an optical mapping system.
186 dvances, we developed and validated low-cost optical mapping systems for panoramic imaging using Lang
187                                              Optical mapping technique was used to assess effects of
188 ed preparations of left ventricle (LV) by an optical mapping technique.
189 in geometrically defined cell cultures using optical mapping technique.
190 hock-induced DeltaV(m) was measured using an optical mapping technique.
191 s in DNA repair, were directly visualized by optical mapping techniques after gamma irradiation.
192 studied ventricular defibrillation by use of optical mapping techniques failed to observe an initial
193                                      We used optical mapping techniques to study the effects of propr
194                                              Optical mapping techniques were used to determine the pa
195 To address these mechanisms, high-resolution optical mapping techniques were used to measure action p
196                    Imaging methods utilizing optical mapping techniques will need to account for thes
197                                           By optical mapping techniques, action potential duration (A
198                                        Using optical mapping techniques, calcium transients and actio
199 g voltage-sensitive dyes and high resolution optical mapping techniques, we found that uncoupling of
200 ion and contraction; (6) new multiparametric optical mapping techniques; and (7) photon scattering ef
201 ating the potential benefit of more accurate optical mapping technologies, such as nano-coding.
202                      Previously, we used new optical mapping technology to image VF wavefronts from n
203 e compared to sham mice by echocardiography, optical mapping, telemetry electrocardiographic monitori
204 onstrate the use of technology developed for optical mapping to acquire DNA fingerprints from single
205 icroscopy, immunochemistry, patch-clamp, and optical mapping to assess the interactions between AnkG,
206                                      We used Optical Mapping to create genome-wide restriction maps o
207                                      We used optical mapping to reconstruct patterns of activation du
208                         The applicability of optical mapping to this problem was enhanced by advances
209                                      Cardiac optical mapping uses potentiometric fluorescent dyes to
210                                              Optical mapping using voltage-sensitive dye revealed slo
211                                              Optical mapping using voltage-sensitive fluorescent dyes
212                                         Thus optical mapping was advanced to use simply extracted, un
213                                              Optical mapping was performed in 44 rat ventricular myoc
214                                              Optical mapping was performed on epicardial, endocardial
215                                              Optical mapping was performed to evaluate diastolic spon
216                                              Optical mapping was used to assess bidirectional conduct
217                                              Optical mapping was used to measure action potential dur
218                              High-resolution optical mapping was used to measure conduction velocity
219                              High-resolution optical mapping was used to study conduction in the righ
220                                        Using optical mapping we observe increased dispersion of actio
221                                        using optical mapping, we investigated the effects of I(Kr) up
222                Illumina, 454 sequencing, and optical mapping were used to obtain a complete genome se
223                                 Whole-genome optical mapping (WGM) (OpGen, Inc.) was performed on sel
224               Whole-genome mapping (formerly optical mapping), which is a high-resolution ordered res
225  ventricular arrhythmias (VA) were probed by optical mapping, whole-cell patch clamp to measure actio
226                              High-resolution optical mapping with correlative histological analysis o
227 etic and optogenetic fluorescent probes; (5) optical mapping with motion and contraction; (6) new mul
228       Chromosome 2 was found to be 976 kb by optical mapping with NheI, and 946 kb with BamHI, which
229                                              Optical mapping with the voltage-sensitive dye di-4 ANEP
230 d variation by integrating our findings from optical mapping with those from DNA sequencing-based gen
231                                              Optical mapping with voltage-sensitive dyes provides a h
232                        Using high-resolution optical mapping with voltage-sensitive dyes, we measured
233 ing of impulse propagation, as determined by optical mapping with voltage-sensitive dyes.

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