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1 ion of fistulas that are unlikely to develop optimally.
2 morbidity and mortality rates if not treated optimally.
3 ibit preferences in the mRNAs they translate optimally.
4 itment nor intention recognition can perform optimally.
5 tment of effort to exploit the contingencies optimally.
6 imates in which the human organism functions optimally.
7 s with vestibular and proprioceptive signals optimally.
8 drenergic signaling, the salience network is optimally able to engage the executive control network t
9 lly involve negative edges, which may not be optimally accounted for by existing approaches to modula
10 rikingly altered by attention most likely to optimally achieve the behavioral goal.
11 utic efficacy as early as possible, which is optimally achieved by three-dimensional imaging given th
12                       No indicator performed optimally across assessments.
13 enders the Fc-FcgammaR interaction unable to optimally activate effector cells.
14                      Lkb1-null SCs failed to optimally activate mitochondrial oxidative metabolism du
15 of selected targets indicated that most were optimally activated by a 100-fold lower concentration of
16 ffects of calcipotriol and 5-FU treatment in optimally activating a CD4+ T cell-mediated immunity aga
17 n rate analysis demonstrated that pool 7 was optimally active at the 5- to 10-mug concentration.
18 urrent and future generations of tools might optimally adapt to the future of NR signaling research.
19                   Animal sensory systems are optimally adapted to those features typically encountere
20                      The agenda also aims to optimally address the prospective effect of ZIKV exposur
21 itional cooling centers, what placement will optimally address the vulnerability of the at risk popul
22 e shows enantiomeric discrimination where 9a optimally addresses the ligand binding pocket of RXR.
23 e; (3) appropriately prescribed BPG; and (4) optimally adherent to BPG (>80% of prescribed doses).
24                     The model parameters are optimally adjusted by using the available data from the
25                    In adolescence, behaviour optimally advances towards adaptive long-term goals and
26 onsume, additional health care resources and optimally affect patient care.
27                                              Optimally aligned phases (or high-excitability states) p
28                       While neither state is optimally aligned to the OPSA, each input state is equal
29 onds that are held in a conformation that is optimally aligned with the amide pi-system, thus allowin
30  a spatially explicit, best-use framework to optimally allocate cellulosic biomass feedstocks to ener
31 d to determine which studies to replicate to optimally allocate limited resources into replications.
32                                           To optimally ameliorate brain monoaminergic neurotransmitte
33 ing depressive symptom episodes and performs optimally among those with initial low-level symptoms.
34  the likelihood that the brain will function optimally and in the absence of disease throughout life.
35 retically show that the locally-blazed trail optimally and robustly exploits useful knowledge while a
36 eshold of physical activity is needed to age optimally and to maximise the 'healthspan'.
37 rks in two phases: The first phase is solved optimally, and for the second we propose several efficie
38  subject to unremitting pressure to function optimally, and this depends on them assuming and maintai
39 ric ultimatum game (UG), humans fail to play optimally as defined by the Nash equilibrium.
40 em." Behaviorally, humans solve this problem optimally as predicted by Bayesian Causal Inference; yet
41 esults from drug susceptibility testing and, optimally, associated patient outcomes.
42 baculum calidifontis, an organism that grows optimally at 90 degrees C.
43 perthermophile Aeropyrum pernix, which grows optimally at 90 degrees C.
44 acterium leprae, which causes leprosy, grows optimally at approximately 30 degrees C, so we sought to
45                             The strip worked optimally at pH 7.0, temperature 25 degrees C and 6min o
46 ative abundances: the mesophilic clade grows optimally at temperatures 16 degrees C higher than the p
47 ever, in hyperthermophilic archaea that live optimally at temperatures above 80 degrees C the membran
48 on exosome structural integrity and occurred optimally at the acidic pH typical of urine from omnivor
49 ndergoes autoprocessing and self-activation, optimally at the physiologically relevant pH value of 3.
50 re enigmatic, because any deviation from the optimally attractive blend should be selected against.
51                                   Though not optimally balanced in this case, this work presents evid
52 lable solvent, 2-trifluoromethyl-2-propanol, optimally balances monomer, polymer, and catalyst solubi
53 s important next step in PH patient care can optimally be addressed through a consortium of study sit
54 onsequences of optogenetic stimulation would optimally be recorded by non-invasive optical methods.
55 nt (P4) in whom the chip was not functioning optimally because of a combination of iatrogenic intraop
56 eptor clustering allow cells to discriminate optimally between pathogens and nonpathogens.
57 ausing pneumonic plague before it evolved to optimally cause invasive infections in mammals.
58 inants of morbidity and mortality, which are optimally characterized by invasive hemodynamic measurem
59                                          The optimally chemically modified siRNA-GalNAc conjugates ar
60  this paper, we explore the vortex matter of optimally Co-doped BaFe2As2 thin films with extended pla
61 ases superconducting-ordering temperature in optimally cobalt-doped BaFe2As2 crystal (T c = 23 to 25
62 nal subcutaneous adipose tissue samples were optimally collected, stored, and analyzed by using high-
63                               The target was optimally coloured for crypsis in a reference orientatio
64 However, there is limited evidence on how to optimally combine matching with subsequent analysis appr
65 residue contact changes between domains were optimally combined by logistic regression using the trai
66 n a combination of intermittently extracted, optimally combined quantitative electroencephalography m
67 6000-fold), high potency and selectivity are optimally combined with superior physicochemical propert
68 in a population of noisy neurons, while also optimally compensating for sensory distortion and noise.
69                     Here, we investigate how optimally competitive tree allocation should change in r
70 ed for high-frequency cells that are instead optimally configured to encode sustained, graded respons
71 old increase in FAIMS peak capacity over the optimally configured unmodified device.
72 ociated measurements that should be taken to optimally constrain the uncertain dynamics of a biologic
73 ity in pre-miRNA ab initio prediction, which optimally contributes to advanced studies on miRNAs, as
74 ase analysis for identifying peptides, which optimally contributes to the challenging task of protein
75 ng TCD8 are functionally impaired and do not optimally control viral replication.
76 archical network of oscillators organized to optimally coordinate behavior and physiology with daily
77 er which both generates the movement and can optimally correct for errors that arise within a movemen
78                Further examination on how to optimally counsel women about surgical options is warran
79                Further examination on how to optimally counsel women about surgical options is warran
80  room-temperature terahertz detectors for an optimally coupled device, and time-resolved measurements
81 siderophores in hvKP infection have not been optimally defined.
82 named DAFODIL (Doxorubicin And 5-Flurouracil Optimally Delivered In a Liposome) that inarguably offer
83 1 vaccines doses are limited, these would be optimally deployed in highly populated urban centers and
84                                           To optimally design next generation catalysts a thorough un
85 cay need to be understood better in order to optimally design vaccines and therapeutics.
86 tic waves (taSSAW), which are oriented at an optimally designed inclination to the flow direction in
87                                          The optimally designed LWA is sintered in comparatively low
88 gh the use of the limited materials palette, optimally designed micro- and nanostructures, and tightl
89 y chosen permutation of immunization with an optimally designed mixture (using the principles that we
90                      The decorated plate was optimally designed to adjust the effective impedance of
91 t the olfactory receptor selection system is optimally designed, and particularly underscores coopera
92  Micro- and nanoscale surface textures, when optimally designed, present a unique approach to improve
93               Filtrate PRP collected from an optimally-designed CIF device typically showed a ~1000-f
94    Moreover, the non-covalent complexes were optimally detected at wavelengths corresponding to a rel
95  pressure (BP) components in young adulthood optimally determine cardiovascular disease (CVD) by midd
96                        Along these lines, we optimally digitize fermionic models of molecular structu
97   Theoretical analyses suggest that water is optimally distributed in the mesophyll when the lateral
98                                      This is optimally done by interrogation of paired H chain V regi
99  TC from 24 to 41.5 K upon surface doping on optimally doped Ba(Fe1-xCox)2As2.
100 tial elastoresistance measurements from five optimally doped iron-based superconductors to show that
101  Eliashberg calculations to show that nearly optimally doped NaFe0.978Co0.022As exhibits some of the
102 -dependent magnetic penetration depth in the optimally doped nodeless s-wave Fe-HTS Ba0.65Rb0.35Fe2As
103 adherence to a combination of at least three optimally dosed antihypertensive medications, one of whi
104 -K326I/A327Y/L328G (IYG) and N297D/S298A-IYG optimally drove tumor cell phagocytosis.
105 n policies need to be enacted urgently to be optimally effective and that strategies to mitigate pand
106 e a challenging population in urgent need of optimally effective therapies.
107           It will be ideal to deliver equal, optimally efficient "doses" of sunlight to all cells in
108  Comprehending speech involves the rapid and optimally efficient mapping from sound to meaning.
109 ages: ultrathin sheets automatically achieve optimally efficient shapes that maximize the enclosed vo
110 z forces partially cancel, and convection is optimally efficient.
111 g evidence suggests that sensory neurons can optimally encode natural stimuli by ensuring that their
112 nd suppression to allow pyramidal neurons to optimally encode visual information independent of behav
113 hat only a small fraction of sensory neurons optimally encoded natural stimuli through high-pass filt
114 al skill sets from real-time job postings to optimally equip trainees for an array of careers to effe
115 though adults older than 55 years of age are optimally evaluated by using ASGE guidelines, younger pa
116                                           To optimally exploit nanomedicines, understanding their bio
117 e-driven conformational transitions that may optimally expose the co-receptor docking site on MHC.
118  expression of lngA, lngR and lngS genes was optimally expressed at 37 degrees C at pH 7.5.
119                                           To optimally facilitate patient selection for Wee1 inhibiti
120 pathways in which BMP keeps lens cells in an optimally FGF-responsive state and, reciprocally, FGF en
121   The lens shapes often need modification to optimally fit corneas of individual test subjects.
122  the local phase modulation only and operate optimally for a specific angle.
123 superior metaplastic models perform close to optimally for a wider range of model parameters.
124 de is located at the active site, positioned optimally for catalysis, whereas the C-terminal moiety o
125 ion events are dispersed evenly and arranged optimally for genetic exchange and efficient chromosome
126 d and the graphene-sheet pattern is designed optimally for maximizing the responsivity.
127 luation with (18)F-FDG PET/CT performed most optimally for the prediction of response on a later CT s
128                                              Optimally formulated gels of antiretroviral drugs are un
129 teins (LDL), were consecutively pasteurised, optimally freeze-dried, and dispersed in various NaCl so
130 , that humans can integrate information near optimally from several perceptual dimensions (color, tex
131                               In addition to optimally functioning with an E2 that solely performs tr
132                      The tertiary radical is optimally generated from the hemioxalate salt of the cor
133 s and rigidifies the DEKA pore to bind Na(+) optimally, highlighting the importance of lysine's nonob
134  that closely resembles the Fermi surface of optimally hole-doped cuprates, including its [Formula: s
135 g such efforts in the population at large to optimally identify those with presymptomatic type 1 diab
136  by a recombinant Pichia pastoris strain was optimally immobilised on Glyoxyl-Sepharose CL 4B using t
137  recycled water to spreading basins could be optimally implemented.
138  that hits the market to ensure they perform optimally in all settings.
139 apture mechanisms that permit people to play optimally in an evolutionary context.
140 dings for understanding how organisms invest optimally in immunity in the light of context-dependent
141 orking memory induced by ketamine and did so optimally in the 40-70% GlyT-1 occupancy range.
142 markers to be developed to use this approach optimally in the clinic.
143 has been evolutionarily selected to function optimally in the crowded milieu of the cell.
144  a large, bulky side chain that does not fit optimally in the wild-type TEM-1 active site.
145   Even so, these converted cells perform sub-optimally in transplantation studies.
146 s applied in a theta-burst pattern, shown to optimally induce LTP.
147  we show that EPSP-spike pairing at 6 Hz can optimally induce STDP at the mossy fiber-granule cell sy
148 a, and concurrent exposure to both cytokines optimally induced DC-HIL expression by tumor-infiltratin
149 e expectation that the experimental data can optimally inform future model improvements.
150 delineate reliable, predictive biomarkers to optimally integrate lenalidomide into lymphoma treatment
151 nted as a Java Cytoscape app, can be used to optimally integrate prior biological knowledge with meas
152                             Human adults can optimally integrate visual and non-visual self-motion cu
153                                          The optimally integrated ensemble LAI changes are significan
154 sian inference includes how sensory cues are optimally integrated over time.
155 f three Bayesian observer models that either optimally integrated the information across all spatiote
156 t rather controls how sensory information is optimally integrated with ongoing processes to guide net
157 common object-tracking system--a system that optimally integrates sensory signals with a realistic mo
158  Despite the existence of various models for optimally integrating reward under uncertainty, the unde
159 that later in childhood humans can gain from optimally integrating spatial cues even when in the same
160          This suggests that AGT proteins are optimally juxtaposed when the DNA is near its torsionall
161                              In an effort to optimally leverage 4-1BB-mediated immune activation, the
162 d access to novel therapeutics are needed to optimally leverage results from broad-based genomic test
163 ance and accelerate the BRAIN Initiative and optimally leverage the effort and creativity of individu
164 acid, a potent inhibitor of bone resorption, optimally linked through a differentially hydrolyzable l
165                    Platelet TFPIalpha may be optimally localized to dampen initial thrombin generatio
166 ct females when mating opportunities are sub-optimally low.
167  machines ensure that protein homeostasis is optimally maintained for cell health.
168  coagulopathic bleeding that is difficult to optimally manage using standard hemostatic testing.
169       Participants' asthma and rhinitis were optimally managed by study physicians on the basis of gu
170                  Currently, CVD is not being optimally managed in this rural area of South Africa.
171 .58-0.93; P=0.014) and need for transfusion (optimally matched adjusted odds ratio, 0.70; 95% confide
172 was associated with a reduction in bleeding (optimally matched adjusted odds ratio, 0.74; 95% confide
173                                       In the optimally matched analysis, compared with bolus plus inf
174 eatment) in sequentially, propensity-scored, optimally matched patients by using multivariable hazard
175 vitamin C in under-ripe (125.87mgkg(-1)) and optimally mature fruit (127.66mgkg(-1)).
176                                              Optimally mobilizing the immune system will likely requi
177 ns, and additionally produces an output that optimally model experimental electroencephalograph (EEG)
178 his pathway may provide insights into how to optimally modulate the PD-1 pathway in cancer immunother
179  technology consists of microring resonators optimally n-doped to support high Q resonances alongside
180 rom Pyrococcus furiosus (PfSHI), which grows optimally near 100 degrees C.
181 nizing lateralized gamma strings to converge optimally on CA1 targets.
182                                           PS optimally opened the SB ostium without deforming the mai
183 o static routes with two riders per vehicle (optimally) or three (with heuristics).
184                                              Optimally orchestrating complex behavioral states, such
185  Approximately three SB-JMR-TMDs per vesicle optimally ordered the bilayer interior and excluded wate
186 tly regulated during ovulation to produce an optimally organized actomyosin network in C. elegans spe
187 at subjects do, in fact, accumulate evidence optimally over time and across sensory modalities, even
188         The lead formulation, DB4-PDB12, was optimally PEGylated not only to ensure colloidal stabili
189 amline study conduct in an ethical manner to optimally perform clinical trials in the electronic age.
190 re particular circuits/chips are designed to optimally perform particular functionalities, require a
191                                       How to optimally perform these reforms is a scientific problem
192 orphology and charge-transport properties of optimally performing BHJ films.
193 mbrane junctions are licensed to respond and optimally placed to be activated by endogenous IP3 and t
194 intricate interactions at the interface that optimally position acyl carrier protein for acyl deliver
195  three-dimensional focusing of the sample to optimally position particles to amplify the size-depende
196 symmetric growth response enabling plants to optimally position their organs.
197           The imidazole styrylbenzamides are optimally positioned to allow interaction of the imidazo
198                      Thus these residues are optimally positioned to mediate crosstalk between functi
199                             Thus, Spire1C is optimally positioned to serve as a molecular hub that li
200 domain as a scaffold for factor binding that optimally positions Stu2 on the mitotic spindle to promo
201                                  Learning to optimally predict rewards requires agents to account for
202                              Calculating the optimally predictive representation of the fly's future
203 rther development of both vaccine viruses to optimally prepare for the further spread of clade 2.2.1
204 umb in selecting the laser power required to optimally prepare the sample for imaging.
205        Thus, Slx9 functions as a scaffold to optimally present RanGTP and the NES to Crm1, therefore,
206 e being how to select a surfactant that will optimally preserve the individual structure and function
207 re essential to guide policy and programs to optimally prevent, detect, and cure infection.
208 ed cohort; four aged nonhuman primate brains optimally processed for molecular investigation; and tar
209 ination of various viral and host factors to optimally produce infectious virus particles.
210 all patients for an additional 3 months, and optimally programmed during serial visits as dictated by
211  are required in the donor graft for AzaC to optimally protect against GvHD and that nTregs, unlike T
212 oth cell-mediated and humoral immunity might optimally protect against secondary S. aureus SSTI.
213 steriors from which sensory estimates can be optimally read out.
214 uration than branching ablation patterns and optimally reduced disease burden when positioned at a ti
215 we rely on traditional measures that may not optimally reflect benefits of new treatments.
216 8-day definitions of postoperative mortality optimally reflected surgery-related mortality after hepa
217 e overall mortality rates at 99 and 118 days optimally reflected surgery-related mortality after hepa
218 lize and fine-tune suppressive mechanisms to optimally regulate and restrain distinctive self and ant
219 put is condensed by our perceptual system to optimally represent and store information.
220 between ASC PYD and procaspase-8 tandem DEDs optimally required both DEDs and represents an unusual h
221 l envelope but not with recombinant SpA, and optimally required five tandem repeats of its Ig-binding
222 ty with blood, molecular imaging of aneurysm optimally requires highly sensitive tracers with rapid b
223 e activity to maintain internal homeostasis, optimally respond to a dynamic external environment, and
224 essential process for most organisms, has to optimally respond to changes in the metabolic demand or
225 ystem has tailored its effector functions to optimally respond to distinct species of microbes.
226 ial for those cases of glaucoma that are sub-optimally responsive to conventional pressure-reducing m
227  inhibition of MAPK signaling is required to optimally restore expression of thyroid differentiation
228 xpressing a novel dystrophin construct which optimally restores proteins of the dystrophin glycoprote
229                                              Optimally ripe and over-ripe blackberries contained sign
230 raCT number: 2011-000393-61) was to find the optimally safe and effective allergoid dose by evaluatin
231 e the distribution of doubling times of such optimally scheduled self-replicating factories, and find
232 niversal distribution, suggesting E. coli is optimally scheduling its replication.
233 inear Programming (ILP), enabling us to find optimally scoring sets of modules.
234 he algorithms previously used were unable to optimally search over all long chains.
235 level of 0.72 x 10(8) CD8 cells per kilogram optimally segregated patients receiving CD8(hi) and CD8(
236                       An efficient method to optimally select the regularization parameter is propose
237 el, the parameters of the transformation are optimally selected by Bartlett's likelihood-ratio test s
238 ocesses (EGFR signaling and DNA repair) with optimally selected experiments.
239  linear decomposition of SRS images at three optimally selected Raman shifts.
240 ns of each team-member's role may facilitate optimally shared responsibility for patient care within
241 iticality provides an adaptive advantage and optimally sized aggregates for the dispersal of spores.
242 ed tissue samples into chunks (20 mum thick) optimally sized and mounted for efficient, parallel FIB-
243 iwi-interacting RNA intermediates to achieve optimally sized piwi-interacting RNAs.
244 ge circuits that promote invariance, whereas optimally sized, smaller stimuli result in contrast vari
245 w algorithms that use integer programming to optimally solve this problem, one of which is inspired b
246 olycehpalum are macro-scale structures which optimally span multiple food sources to avoid repellents
247 point mutations are then combined to make an optimally stable MP that is suitable for structural biol
248  MPs and how to combine mutations to make an optimally stable mutant suitable for structural studies.
249 ce reduced levels of IL-18 and are unable to optimally stimulate IFN-gamma production by NK cells.
250 ting that this adjuvant formulation may have optimally stimulated innate and adaptive immunity to eli
251 -dependent stimulation of dermal fibroblasts optimally stimulates epidermal stem cell proliferation.
252                          Second, we simulate optimally strengthening ties within entrepreneurial ecos
253 ssumed that organisms use neural information optimally, such that any information available in a neur
254 e function, to determine which subset may be optimally suitable for a given clinical situation.
255 odular design and interchangeable format are optimally suited for integration with existing computati
256                                              Optimally, supplements should make results findable, acc
257 ensure that their plasma membranes (PMs) are optimally supplied with cholesterol derived from uptake
258 t is, these levels of alpha rhythm seemed to optimally support the behavioral goal ("detect" stimuli
259 e based on an azobenzene photoswitch that is optimally switched into the liganding state by blue or n
260                              By employing an optimally synthesized 2-microm mid-infrared laser and a
261 eed to establish experimental paradigms that optimally tap into the marmosets' behavioral and cogniti
262 The goal of precision medicine is to deliver optimally targeted and timed interventions tailored to a
263 together with the challenge of incorporating optimally the limited information into models of disease
264                     Recently, a strongly and optimally tightened lower bound on the exchange energy w
265 ction factor to adjust for biases due to non-optimally timed sampling.
266 quent decades, many different strategies for optimally titrating PEEP have been proposed.
267  explored whether the immune system responds optimally to antigen kinetics most similar to replicatin
268 an increased safety risk as they may respond optimally to cross-reactive peptides.
269  of patients who also appear to respond less optimally to DBS by other indicators of QOL.
270 ensory and prior information can be combined optimally to guide behavior.
271 solution and can program their eye movements optimally to maximize information acquisition for a vari
272 owever, the majority of MSTd neurons respond optimally to spiral patterns, rather than to the radial
273 s used for AIT, some patients do not respond optimally to the treatment.
274  painful diabetic neuropathy who may respond optimally to therapies such as duloxetine.
275 abilization problem in FC and microarrays by optimally transforming data with the help of Bartlett's
276 d discusses the need for further research to optimally treat heart failure.
277                                To achieve an optimally tuned adaptive response, it is critical that t
278 afast PCET reactions inside nanocages and if optimally tuned should provide a novel paradigm for visi
279 new method to control metabolism by inducing optimally tuned time-oscillations in the levels of selec
280 ity at predicting the envelope was similarly optimally tuned to a nonzero level of variability in bot
281 s --> RHOA/C --> actomyosin pathways must be optimally tuned to compromise between generation of moti
282 demethylating agent (DAC) individually could optimally up regulate VDR in HIV milieu.
283 lty in being able to use this information to optimally update outcome predictions might contribute to
284 e of a novel mechanism that enables cells to optimally use IL-7.
285 neous metastases and treatment algorithms to optimally use the available skin-directed therapies are
286 he combined techniques thus provide a way of optimally using the complementarity of the available met
287 icities, and this has limited our ability to optimally utilize existing drugs or to develop new drugs
288  appropriate and whether resources are being optimally utilized in meaningful ways.
289 vant and delivery approaches are required to optimally vaccinate at this site.
290 tal illness.SIGNIFICANCE STATEMENT To choose optimally, we have to learn what to expect.
291 ability, suggesting that OFC guides behavior optimally when contingencies apply consistently.
292 nce that HA stalk-binding antibodies perform optimally when in a polyclonal context and that the targ
293 the role of N-cadherin in the development of optimally wired neurite fascicles in the peripheral visu
294 ad MMP inhibitor protein N-TIMP2 to interact optimally with MMP-14.
295 ensor has a large dynamic range and partners optimally with optogenetic probes.
296 cause an H-bond positions the QA to interact optimally with the rings, and weakly to Cho because a di
297 onal classification systems do not correlate optimally with underlying melanoma growth-promoting muta
298     Lactate biosensors reported so far, work optimally within 3-180s, between pH, 5.5-8.5 and tempera
299 man umbilical vein endothelial cells respond optimally within a range of fluid shear stress that appr
300 ynthesize and utilize proteins that function optimally within a subset of growth conditions.

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