ライフサイエンスコーパス: optimisation

1 ning the theoretical generality of Levy walk optimisation.

2 these systems lack the flexibility for easy optimisation.

3 nducting oxide and thermo-electric materials optimisation.

4 gulation and could find applications in gene optimisation.

5 ity, oxidation and on-line analysis and self-optimisation.

6 they are particularly applicable to potency optimisation.

7 a more suitable one for ligand discovery and optimisation.

8 ew opportunities for drug discovery and lead optimisation.

9 ent, patients received 6 weeks of medication optimisation.

10 generated, and transcriptomic prediction by optimisation.

11 matrix completion by using nonlinear convex optimisation.

12 lications thereby paving the way for further optimisation.

13 and, like tapasin, works to enhance peptide optimisation.

14 rapy for pouchitis patients requires further optimisation.

15 to allow time for myasthenic status and drug optimisation; (2) multidisciplinary liaison through the

16 m video recordings of bending tests, (ii) an optimisation algorithm for the characterisation of Young

17 The image optimisation algorithm minimises a cost function incorpo

18 ecular interaction networks, we developed an optimisation algorithm that integrates databases of know

19 ation of a two-joint planar robot arm and an optimisation algorithm was used to find the optimum matr

20 ction of signalling pathways, module-centric optimisation algorithms, whose aim is to identify sub-ne

21 and short plasma exposures are required for optimisation and clinical translation of cold plasma tec

22 Further research is needed to inform dose optimisation and co-trimoxazole use in the context of ex

23 Here we report the optimisation and evaluation of an electrochemical biosen

24 ach brain and support the continued clinical optimisation and evaluation of Posiphen for MCI and Alzh

25 s them with respect to their use in antibody optimisation and highlights how they can be exploited fo

26 ting studies, and more use should be made of optimisation and probabilistic modelling approaches that

27 ogress, standardisation of research efforts, optimisation and training of an experienced and non-conf

28 n, Na, Ni, Pb, Sr and Zn were analysed after optimisation and validating the analytical method using

29 We report the optimisation and validation of a label-free, real-time c

30 This study describes the optimisation and validation of a very sensitive method f

31 This study describes an optimisation and validation process using liquid chromat

32 s of the clinical study (preliminary safety, optimisation, and feasibility vs preliminary efficacy vs

33 o be further impacted unless efforts towards optimisation are carried out.

34 n model and data which persist despite model optimisation are used to flag up important questions con

35 Optimisations are described which appear to reduce the w

36 tive features will guide future nanoassembly optimisation, as well as the development of the new gene

37 dy this shortfall, we present multi-response optimisation based on Response Surface Methodology (RSM)

38 Optimisation-based dynamic simulations were performed to

39 cell culture, and xenograft methods for lead optimisation before clinical trials are contemplated.

40 g flour) on the quality of bread flour after optimisation by additions of alpha-amylase.

41 ng a peptide editor, TAPBPR improves peptide optimisation by promoting peptide-receptive MHC class I

42 At the same time such optimisation can also help refine model parametrisation

43 Further optimisation can be achieved by targeting policies at th

44 Further optimisation can lead to a viable, safe and non-invasive

45 fications for fundamental aspects, while its optimisation clearly has an impact on technology (e.g.,

46 veal how variation in LL emerges from carbon optimisation constrained by both leaf structural traits

47 Using optimisation criteria based on minimisation of muscle st

48 investigated and optimised using univariate optimisation design.

49 Optimisation did not compromise the detection of other o

50 uvant Lapatinib and/or Trastuzumab Treatment Optimisation) enrolled 455 women with invasive human epi

51 and validation of the program GOLD (Genetic Optimisation for Ligand Docking).

52 res fitting of potentiometric data using the optimisation function of the Solver add-in of Microsoft

53 s a wealth of papers dealing with extraction optimisation, identification and quantification of HTs.

54 As a result of the SBSE optimisation, improved detection limits and linear range

55 Synthesis and optimisation improvements are proposed.

56 r tumour recurrence is crucial for treatment optimisation in metastatic breast cancer.

57 but has a narrow therapeutic index and dose optimisation is challenging.

58 hat parasite-focused toolbox development and optimisation is critical.

59 In such optimisations, it is common to maximise the discounted u

60 uption resulting in automation and cognitive optimisation lack in MS.

61 Using non-linear optimisation methods, we examined how these optimum pack

62 1, 0, +1 and +1.414) were used to design the optimisation model using central composite rotatable des

63 Gene weights are determined by the optimisation model, in a way that the resulting pathway

64 poling penalty function inside the resulting optimisation objective function.

65 Optimisation of a dip-coating method enabled significant

66 Optimisation of a microwave-assisted methanolysis was pe

67 Detailed characterisation and optimisation of a new CDH/AuNP-based bioanode were perfo

68 et of model observables of interest, studied optimisation of a objective function, or have not dealt

69 This paper describes the optimisation of a screen-printing water-based carbon ink

70 le sugar glass MNs were fabricated following optimisation of a simple and novel low temperature vacuu

71 ttings with limited resources, investment in optimisation of adherence rather than implementation of

72 MBP-hFGF21 construct was further pursued for optimisation of affinity chromatography purification.

73 Optimisation of an analytical procedure for the separati

74 ebral oxygen saturation monitoring to enable optimisation of anaesthesia depth and cerebral oxygen sa

75 In this study we evaluate the extraction optimisation of anthocyanins and total phenolics in D. h

76 quacy of experimental controls, insufficient optimisation of assay performance as well as lack of tra

77 ntered biological media and analytes hampers optimisation of biosensor performance for maximum sensit

78 c approach to the invention, development and optimisation of biotransformations utilising isolated en

79 ased on a combination of antiplatelet drugs, optimisation of blood pressure and LDL cholesterol value

80 Optimisation of breastfeeding practices could reduce hig

81 e potential to improve patient selection and optimisation of cardiovascular interventions across a ra

82 Optimisation of cellular activity and characterization o

83 This study focuses on the optimisation of cheese whey formulated media for the pro

84 nvironmental conditions and for experimental optimisation of complex combined experiments.

85 e new tools for the downstream, preclinical, optimisation of compounds.

86 entail new biology-driven approaches, since optimisation of conventional treatments has in many case

87 These results may facilitate the optimisation of delivery systems for lipophilic bioactiv

88 Optimisation of effectiveness and coverage of interventi

89 arch should focus on the rationalisation and optimisation of existing programmes, with particular att

90 learning has important implications for the optimisation of experimental breeding programmes in the

91 The optimisation of experimental conditions was performed.

92 on of brain perfusion (flow), as well as the optimisation of extraction oxygen mechanisms (misery per

93 increased and provides the basis for further optimisation of FFS as simple, convenient and sustained

94 propriate (focusing on limb preservation and optimisation of function).

95 rted if complications were prevented through optimisation of general health status and if complicatio

96 but management of vascular risk factors and optimisation of glycaemic control could have therapeutic

97 esulted in guidelines worldwide recommending optimisation of glycosylated haemoglobin, but no trial r

98 as a simple and reliable maturity index for optimisation of harvest time.

99 f HBc particles in bacteria is demanding and optimisation of HBc particle yield from E. coli is requi

100 ETATION: Housing-level policy related to the optimisation of healthy density in cities might be a pot

101 dictive capability for use in the design and optimisation of high efficiency lasers in the infrared.

102 Here we show the design and optimisation of hybrid DNA-RNA CRISPR and tracr molecule

103 In complex social species, the optimisation of individuals' network position has import

104 retical model and provide a step towards the optimisation of laser-mediated gene delivery into mammal

105 an efficient and systematic approach to the optimisation of lipase-catalysed biological processes.

106 One constraint is optimisation of national biosafety processes to support

107 In this study, optimisation of natural colorant non-conventional extrac

108 easingly important role in the discovery and optimisation of novel, potent and selective protein kina

109 me a crucial step for the efficiency and the optimisation of numerous molecular biology techniques su

110 e Surface Methodology (RSM) was utilised for optimisation of parameters affecting immobilisation of F

111 ed confirmation of physiological effects and optimisation of parameters in healthy humans prior to tr

112 However such methods require optimisation of parameters in order to control the risk

113 efficiency of copper was obtained after the optimisation of parameters such as extraction and disper

114 and survival for treatments is important for optimisation of patient management.

115 Thus, optimisation of population iodine intake is an important

116 The overall optimisation of preparation conditions was an UT of 14.6

117 Further optimisation of present standard chemoradiation is neede

118 cause of cost and manufacturing constraints, optimisation of protection against all poliovirus types

119 Possible ISSD applications include optimisation of protein expression, improvement of the p

120 hodology (RSM) was used for modelisation and optimisation of protein extraction parameters in order t

121 Optimisation of protein extraction yield from pinto bean

122 Recent developments in the design of tags, optimisation of purification conditions, experimental de

123 carcity of human material for study requires optimisation of research strategies and co-ordination of

124 ation on individual mRNAs, as well as global optimisation of ribosome availability.

125 power and digestion time) were used for the optimisation of sample digestion.

126 ained by the commonly used SPME methodology, optimisation of SBSE achieved better results for volatil

127 Simultaneous optimisation of several conflicting characteristics pose

128 uence with respect to the identification and optimisation of sites accessible to antisense oligonucle

129 Further optimisation of specific androgen-progestin regimens and

130 ual recalibration may be fundamental for the optimisation of speech comprehension, recalibration prob

131 nt trial data, and explore opportunities for optimisation of STEMI outcomes with a pharmacoinvasive a

132 demonstrates that important information for optimisation of such complex bioformulations, including

133 Optimisation of surgery for patients with localised dise

134 ) to assess the modalities that best balance optimisation of survival with the lowest adverse effects

135 genetic algorithm (GA) for the simultaneous optimisation of SVM parameters and pre-processing (GENOP

136 Amperometric optimisation of the assay resulted in limits of detectio

137 One of the methods was chosen for optimisation of the duration of incubation.

138 Optimisation of the experimental parameters was performe

139 This is the first photonic simulation and optimisation of the extensive growth of entanglement in

140 random walk for the prognostic modelling and optimisation of the growth of hESC colonies.

141 After optimisation of the homogenisation procedure, stable emu

142 n participants who completed the study after optimisation of the infectivity assay, had both a pre-tr

143 Optimisation of the laser microdissection technique was

144 Optimisation of the method considered kinetic studies to

145 For optimisation of the method, recovery tests with differen

146 Optimisation of the methods enabled the chromatographic

147 r a fibre channel hinges on the simultaneous optimisation of the modulation format and code rate, bas

148 and the observations were used to guide the optimisation of the process.

149 nhancement of detection was achieved through optimisation of the properties of the redox-tagged pepti

150 different concentration ratios, therefore an optimisation of the ratio is important to produce a solu

151 However, optimisation of the regimen could potentially prolong tr

152 m in a DM fibre laser, which involves manual optimisation of the relative length of fibres with oppos

153 lementary surface and bulk analysis allowing optimisation of the therapeutic effect of such formulati

154 r:ethanol:methanol ratios promoted the joint optimisation of the total phenolic and isoflavone conten

155 , our work opens up new perspectives for the optimisation of their properties.

156 the pathways to be generated, through to the optimisation of those pathways so that more efficient co

157 ical classifications, revealing evolutionary optimisation of translation responses to be strongly inf

158 Optimisation of treatment requires systematic rotation t

159 We herein describe the characterisation and optimisation of two competitive enzyme-linked immunosorb

160 outcomes and quality of life should include optimisation of wound healing to attenuate or prevent hy

161 The optimisation parameters studied were: the carrier flow r

162 After an optimisation period, during which calcium and active vit

163 After the medication optimisation phase and between Jan 6, 2014, and Aug 11,

164 point of approximately 17 ng/ml with further optimisation possible.

165 rent theories of LL that are based on carbon optimisation principles are challenging to quantitativel

166 Haplotyping is currently addressed as an optimisation problem aiming at solutions that minimise,

167 f target regimes is a multi-parameter global optimisation problem.

168 Optimisation problems typically involve finding the grou

169 The optimisation procedure was done in two steps: using a tw

170 As response variables in the optimisation process include main individual polyphenols

171 ronment, thus likely resulting from a neural optimisation process rather than a pre-programmed mechan

172 the base material, as this will speed up the optimisation process.

173 A pre-requisite to medicinal chemistry optimisation programmes required to improve the drug-lik

174 on the sampling (the linear bias) constrains optimisation results to a subspace of optimal solutions

175 s spurred the development of statistical and optimisation routines for parameter inference.

176 analogues were enrolled into a 2-month dose-optimisation run-in period.

177 Compounds were isolated after a solvent optimisation selection based on solute distribution in a

178 l analyses based on product yield across the optimisation set allow an insight into the important asp

179 Through several optimisation steps a suitable method was achieved showin

180 ostulate that sex-specific primordial energy optimisation strategies exist, which developed to help c

181 ical environment; and aid with the design of optimisation strategies for controlled drug release.

182 To demonstrate the existence of these energy optimisation strategies, we recruited 88 healthy adults

183 mide provide a framework for further regimen optimisation strategies.

184 segment external elastic lamina-based stent optimisation strategy was safe and resulted in similar m

185 ube bi-directional ASA with a 'matrix-based' optimisation strategy, speeding up the whole process in

186 Optimisation studies were carried out for amount of micr

187 The optimisation suggested that extraction with 84.5% methan

188 We then use convex optimisation techniques in order to find approximations

189 lass pathway activity inference method using optimisation techniques is reported.

190 transport investigation unveil high level of optimisation that achieves high-brightness white in a th

191 f suboptimal peptides is followed by peptide optimisation that depends on temporary ER retention.

192 This study presents the optimisation through an experimental design then the val

193 selectivity via manual or automated feedback optimisation, thus constituting a dial-a-molecule approa

194 lele system, along with significant upstream optimisation to define the specific test conditions.

195 provides opportunities and scope for product optimisation to improve their nutritive value.

196 pecially abrasive peeling might need further optimisation to make them gentler and minimise bioactive

197 This provides scope for product optimisation, to improve the nutritive value of commerci

198 CDR loops conformation and VH/VL orientation optimisation upon antibody sequence change.

199 ents, providing a platform for their further optimisation using medicinal chemistry.

200 To enable experimental optimisation using the Fisher Information Matrix it effi

201 An additional optimisation was achieved by reducing the grind size of

202 Optimisation was performed to highlight differentially e