ライフサイエンスコーパス: optimise

1 PF are needed if clinical outcomes are to be optimised.

2 h as temperatures, times and gas flows, were optimised.

3 ects of saponification were investigated and optimised.

4 how interventions beyond node removal can be optimised.

5 se and deployment strategies are still being optimised.

6 om diagnosis to viral suppression, should be optimised.

7 sample volume and interference of ions, were optimised.

8 ses (phenolic acids and flavonoids) has been optimised.

9 ries, and management of hypertension must be optimised.

10 es using Accelerated Solvent Extraction were optimised.

11 pH and extraction temperature and time, were optimised.

12 Several important dSPE parameters were optimised.

13 suggesting that their configuration might be optimised.

14 Conditions for beverage preparation were optimised.

15 a cell line where other conditions have been optimised.

16 ular components, the activity of each can be optimised.

17 nd ionic strength of the final solution were optimised.

18 The extraction procedure was optimised: 420 mum particle size, extraction with 5% tri

19 ino nitrogen ratio of crude hydrolysates was optimised (80.2g/g) in fed-batch cultures of R. toruloid

20 This work used a central composite design to optimise a reverse phase high performance liquid chromat

21 In this study, we optimised a PCR random assembly approach to generate pro

22 e model, identified with a genetic algorithm optimising accuracy/complexity measures, faithfully repr

23 Results open the possibility of optimise alternative technological applications to tradi

24 ting excess drug concentrations and helps to optimise an individual patient's risk of ischaemic and b

25 id Micro-Extraction (USVADLLME) approach was optimised and applied for the first time to a historical

26 rmance of the assay and the sensor was first optimised and characterised in pure buffer conditions gi

27 The QuEChERS method was optimised and different extraction solvents and clean-up

28 Chromatographic conditions were optimised and full scan accurate mass data acquisition u

29 The proposed method was optimised and the validated using standard reference mat

30 mental signals to ensure resource capture is optimised and unfavourable environments are avoided.

31 performance of the Folin-Ciocalteu method is optimised and validated again.

32 The method was optimised and validated to achieve low LODs.

33 The ICW was optimised and validated using monacolin K, the main hypo

34 ession are needed to inform interventions to optimise ART delivery.

35 critical discussion of key parameters to be optimised, as well as of experimental and theoretical te

36 h shows that the target self-charging can be optimised at a pulse duration of few hundreds of fs.

37 meter of 10mum and total length of 31.5cm in optimised background electrolyte with the composition 17

38 nd that given the opportunity, tree crickets optimised baffle acoustics; they selected the best sized

39 However, in many cases it is necessary to optimise beliefs about sequences of states rather than j

40 The optimised biodevice exhibited an OCV of 0.67V and power

41 effective parameters on the extraction were optimised by a central composite design (Box-Behnken res

42 (SPE), of polyphenols from a VOO sample were optimised by a Plackett-Burman experimental design; then

43 oncentrations, the experimental protocol was optimised by applying a "current jump" to the IRMS devic

44 Firstly, oil stability was optimised by comparing the accelerated stability of tuna

45 anisotropy of magnetite nanoparticles can be optimised by doping with transition metal cations, enabl

46 concentration, for a successful coating, was optimised by dynamic light scattering (DLS) and zeta pot

47 oton beams can be efficiently controlled and optimised by employing a recently developed helical coil

48 ion and solubility of hFGF21 were tested and optimised by fusing the protein with one of eight tags:

49 s whose functional performance would be best optimised by improvment in pulmonary mechanics rather th

50 or samples containing starch, the method was optimised by including an additional enzymatic treatment

51 yphenols with high antioxidant activity were optimised by response surface methodology (RSM) in Feron

52 vonoids with high cyto-protective effect was optimised by response surface methodology (RSM).

53 synthetic and metabolic function can only be optimised by the growth of cells within a supportive liv

54 The extraction variables were optimised by the response surface methodology.

55 The extraction step was optimised by using an experimental design.

56 Low-cost but context-specific changes that optimise care processes like prioritisation and transfer

57 ained in this study can serve as a guide for optimising CED treatment regimens.

58 We report an optimised centrifugal counter-flow elutriation protocol

59 individual to generate a precise approach to optimise cerebrovascular health.

60 is sensor could potentially help validate or optimise cleaning practices for a given food manufacturi

61 gulatory hurdles that should be addressed to optimise clinical adoption.

62 rstanding and use of published literature to optimise clinical care, including the science of systema

63 (ALS(SOD1)) will provide key information for optimising clinical trials in this patient population.

64 those of UniRef90 and UniRef50, owing to an optimised clustering pipeline that runs with our MMseqs2

65 e used to search for synthetic lethality and optimise combination protocol designs.

66 At the optimised condition, the CDs-Fe(3+) mixture served as a

67 ms to prevent additional brain damage and to optimise conditions for brain recovery.

68 tectability using the ring resonators and to optimise conditions for solid-phase amplification, hybri

69 l viability, function or proliferation under optimised conditions (5 MBq/mL, 60 min).

70 Using the optimised conditions demonstrated via the solid-phase hy

71 C and ethanol concentration of 65% were the optimised conditions for the response variables of total

72 With our optimised conditions in hand, the system response was li

73 We have optimised conditions to allow long-term mammalian cell c

74 Under optimised conditions we determined the anti-inflammatory

75 Under optimised conditions, extraction efficiencies were incre

76 Under optimised conditions, limits of detection are 0.04 and 0

77 Under the MAE optimised conditions, the recovery of TPC was 162.49 +/-

78 Under optimised conditions, they could be used for histamine s

79 diabetes who need a diuretic-like effect to optimise control of blood pressure, adding meaningful ef

80 We demonstrate how to optimise control via removal of hosts surrounding detect

81 including dosing titration of ponatinib and optimised control of vascular risk factors, might furthe

82 The objective of this work was to optimise conversion of beta-glucoside isoflavones to agl

83 Further research is needed to optimise cooking procedures to enhance retention of vita

84 Using an optimised demagnetisation process, we demonstrate coolin

85 The optimised design focused on increasing the plating solut

86 pid turnover enzyme-substrate complex and to optimise detergents for membrane protein study.

87 ier, a connection that must be unravelled to optimise device performance and enable further applicati

88 Applying the optimised device as a biosupercapacitor in a discontinuo

89 After an 8 week lead-in period to optimise diabetes management, patients were randomly ass

90 The optimised diets had up to 30% lower blue water footprint

91 The optimised diets met nutritional guidelines and minimised

92 ly; however, the distinction is necessary to optimise disease surveillance.

93 nks the nodes, but also provides a naturally optimised distribution of effort to steer a network from

94 n this prospective dose-escalation study, to optimise disulfiram exposure we included adults with HIV

95 Use of synthetic, codon-optimised DNA enabled overexpression of functional PfVIT

96 An evidence-based optimised dose regimen was constructed that would provid

97 the oligosaccharides have been remodelled to optimise effector functions.

98 nts of a conservation strategy that seeks to optimise either biodiversity conservation or ecosystem s

99 We present an easy-to-use, open-source Optimised Exome analysis tool, OpEx that accurately dete

100 Under the optimised experimental conditions, a linear response to

101 urate KDs can be obtained by waterLOGSY with optimised experimental setup.

102 Under the optimised experimental variables, enhancement factor (EF

103 ference methods, while comparable to Zhang's optimised finite difference scheme.

104 This potential was applied by optimising foamy virus vectors carrying the full-length

105 /MS) optimised for basic species, UPLC/MS/MS optimised for acidic species and gas chromatography/MS (

106 ussion of tuneable CD properties that can be optimised for applications in photocatalysis.

107 graphy/tandem mass spectrometry (UPLC/MS/MS) optimised for basic species, UPLC/MS/MS optimised for ac

108 he preparation of truncated natural products optimised for biological activity.

109 y and coacervate yield (%) were measured and optimised for complex coacervation.

110 rotein complexes have been evolutionarily co-optimised for correct function.

111 suggests that individual domains may not be optimised for greater solubility, giving scope for fragm

112 al signals from these novel 'metamaterials', optimised for light reflection or harvesting.

113 immediate treatment, we established a cohort optimised for prevention and cure research.

114 raphy (LC)-gas chromatography (GC), has been optimised for rapid and efficient extraction and analyti

115 d atom experiments and we show how it can be optimised for realistic experimental parameters.

116 esting the neurons' receptive fields are not optimised for recognising abstract shapes, a conclusion

117 A microwave-assisted extraction method was optimised for the recovery of bioactive compounds from C

118 quantitative proteomic methodology has been optimised for the relative quantitation of proteins extr

119 ely used mutation calling algorithms are not optimised for the simultaneous analysis of multiple samp

120 ventions tested in this trial can be further optimised for use at scale, but substantial improvements

121 The optimised formulation was calculated to contain 5.5% OP,

122 -DBP) and this technique is combined with an optimised forward error correction implementation to dem

123 t, especially for supplement formulation, to optimise FSV absorption.

124 rophic lateral sclerosis would have value in optimising future therapeutic trials.

125 Approaches to optimise healing potential of burn wounds use targeted w

126 rates of HIV testing and treatment needed to optimise health and to reduce transmission.

127 mediated cassette exchange to insert a codon-optimised HIV-1 Gag-Pol expression construct in a contin

128 Once optimised HPAEC PAD for the specific matrix, the second

129 d to prioritise public health investments to optimise human development.

130 We optimised hydrogel-embedding and passive clearance of li

131 mphasise the need for urgent (<48 hours) and optimised imaging for patients with suspected invasive f

132 a process whereby the value of grain can be optimised in a way that is traditional, natural and sust

133 The setup was optimised in order to increase the volume of particle in

134 ross-linker and monomer/template ratios were optimised in order to maximise the binding capacity for

135 with pulsed amperometric detection (PAD) was optimised in order to quantify mannose, maltose, maltotr

136 and treatment approaches were developed and optimised in real time.

137 ol biosensors, respectively, which were then optimised in terms of stability and sensitivity.

138 nation of nine triazines in mussels has been optimised in terms of the sorbents used for extracting a

139 risk-based surveillance strategies could be optimised in the country by taking account of highly con

140 Through the use of highly optimised, in-memory data structures and algorithms, Rea

141 Two parallel biosensors were designed and optimised independently, based on each bioreceptor.

142 f local hand, foot, and mouth disease and to optimise interventions.

143 ements on alternate days and in single doses optimises iron absorption and might be a preferable dosi

144 To optimise its properties and exploit it for future memory

145 catalyzed by Candida antarctica lipase B was optimised, leading to the production of 440 g/L vanillyl

146 phenolic capacity (TPC) of leaf extracts at optimised MAE conditions was compared with ultrasound-as

147 The optimised MAE conditions were as follows: extraction tem

148 eriod represents an important opportunity to optimise maternal health before the next pregnancy.

149 self-charging biosupercapacitor based on an optimised mediator- and membrane-free enzymatic glucose/

150 nd sought to encourage healthier lifestyles, optimise medication, and improve treatment adherence.

151 The optimised method solubilises < 40,000 ppm insoluble star

152 The optimised method, applied to the analysis of human milk

153 Applying this optimised method, LODs down to 0.2mugkg(-1) and LOQs dow

154 luble sugars confirms reproducibility of the optimised method.

155 The optimised methodology was applied to assess safety conce

156 These resources and optimised methods enable facile and scalable genome edit

157 are not ideal and gaps exist with paucity of optimised methods, constraints of trial operational supp

158 ither an intensive autoclave treatment or an optimised microwave-treatment achieving 6D-reduction of

159 The obtained optimised model could be used for polyphenol extraction

160 nts with stroke, they would provide a way to optimise motor learning in these patients.

161 We optimised multiparameter readouts to study emerging ther

162 nt canopies, emerge as a plastic response to optimise N utilisation for carbon assimilation.

163 and 4 microm being close to the evolutionary optimised natural prototype.

164 diversity protection would arise solely from optimising net value from an ecosystem service.

165 The optimised New Dutch mini-Luke ("NL"-) method was applied

166 Optimised of the extraction of polyphenol from star frui

167 cs (PHCs) in southwestern Harare implemented optimised, opt-out PITC for all attendees aged 6-15 year

168 tervention and tight control of inflammation optimise outcomes in rheumatoid arthritis but these appr

169 These optimised parameters of cerebellar rTMS can produce sust

170 SFE-CO2 at optimised parameters yielded 8.3g/100g of lipophilic fra

171 In the current study, we optimise passive CLARITY and immunofluorescent labelling

172 opment of predictive biomarkers is needed to optimise patient benefit, minimise risk of toxicities, a

173 ists should be vigilant and work together to optimise patient outcomes.

174 tion and treatment of comorbid conditions to optimise patient outcomes.

175 comes remains largely unknown, yet is key to optimising personalised treatment strategies.

176 We developed European guidelines to optimise phenylketonuria (PKU) care.

177 vided by light and temperature cues helps to optimise plant body architecture and physiology.

178 cks both require explicit consideration when optimising policies to manage tropical carbon and biodiv

179 Further, a genetic algorithm is utilised to optimise polymer constituent blocks in an evolutionary m

180 Optimising pore diameter and fraction in terms of broad-

181 -controlled study, partial responders taking optimised PPI therapy were given 30, 90, 120 and 240 mg

182 For the two datasets, SVM with optimised pre-processing give models with higher accurac

183 se phytochemicals during extraction requires optimised process parameter conditions.

184 ly response surface methodology to model and optimise processing conditions for the preparation of be

185 ogy, blood biomarkers, and brain imaging, to optimise prognostic accuracy.

186 ry weight equivalent) when extracted with an optimised protocol.

187 Optimised protocols enabling the compatible application

188 erosis to manage symptoms, restore function, optimise quality of life, promote wellness, and boost pa

189 nd opens up the use of photonic circuits for optimising quantum devices.

190 slow metabolisers with nicotine patch could optimise quit rates while minimising side-effects.

191 All patients continued optimised RAS blockade treatment throughout the trial.

192 RETATION: TRF-budesonide 16 mg/day, added to optimised RAS blockade, reduced proteinuria in patients

193 P and mercaptophenylacetic acid (MPAA) in an optimised reaction environment to achieve an efficient l

194 for the food industry, seven "nutritionally optimised" ready meals were created at the European leve

195 e parameters, as well as explore how best to optimise recovery and quality of life for survivors.

196 independently coded by three researchers to optimise reliability in reported findings.

197 phropathy and persistent proteinuria despite optimised renin-angiotensin system (RAS) blockade.

198 elopment of more effective CIP conditions to optimise resin lifespan.

199 ey are stimulated chronically, presumably to optimise resource utilisation.

200 493 participants entered a 3 month run-in to optimise risk factor and glycaemic control (single-blind

201 Under optimised sensing conditions, the single stranded CCCVd

202 in state that can emerge as a consequence of optimising sensory information processing.

203 The combination of optimised setup and rough surface increased the particle

204 signed patients (1:1) to receive 3 months of optimised single-lead DBS-either VIM or VO.

205 The InGaZnO TFTs with the optimised SiO2 electrolyte also showed good air stabilit

206 ne-learning principles paves the way to self-optimising 'smart' optical technologies.

207 ates from different ecosystems suggests that optimising some services will be more likely to protect

208 They can also be used to optimise stent implantation to minimise stent-related ad

209 protease activities in a complex manner and optimises storage reserve mobilisation in the transition

210 Optimised synchrotron protocols and simple rules introdu

211 sponse surface methodology (RSM) was used to optimise system parameters.

212 The optimised system was demonstrated to be highly specific

213 s are consistent with germline TCR structure optimising T cell cross-reactivity and immunity by moder

214 We aimed to optimise TDABC for use in a resource-limited setting to

215 population-based pharmacokinetic approach to optimise the antimalarial treatment regimen for piperaqu

216 chieving PET-negativity, and therefore could optimise the chance of cure after HDT/ASCT.

217 Response surface methodology was used to optimise the conditions for preparing stable nanoemulsio

218 The objective of this study was to optimise the depolymerisation of polymers and to investi

219 We optimise the design and experimentally demonstrate near

220 The goal of the present work was to optimise the different environmental friendly processes

221 sed consensus modelling to understand how to optimise the effects of mass drug administration in area

222 impacts of interventions, it is essential to optimise the efficacy of control measures.

223 colorimetric approach was first developed to optimise the experimental parameters and establish the c

224 ysing major steviol glycosides as well as to optimise the extraction and clarification conditions for

225 The purpose of our research was to optimise the extraction conditions of the stir-bar sorpt

226 ts (water, ethanol and methanol) was used to optimise the extraction mixture for phenolics and antiox

227 Policy makers need reliable data to optimise the HIV care continuum and improve individual-b

228 We must optimise the implementation of novel RSV therapeutics by

229 e requirements the OpEx output allows one to optimise the inevitable trade-offs between sensitivity a

230 also implement a simple greedy algorithm to optimise the link order in favour of fast coordination.

231 hould also identify how such information can optimise the management of patients with neuroendocrine

232 e partial least squares regression method to optimise the PLR extract with highest cyto-protective ac

233 creasing diagnosis and treatment rates could optimise the reduction in the burden of disease produced

234 0%)] design of experiments (DOE) was used to optimise the release of dipeptidyl peptidase IV (DPP-IV)

235 suggests there is scope to use NMR status to optimise the selection and efficacy of smoking cessation

236 The aim of this work was to optimise the separation of 17 phenolic compounds already

237 Seeking to optimise the simultaneous use of two antibiotics, we use

238 To efficiently optimise the system, we develop the Optometrist Algorith

239 urately simulate the electronic transport to optimise the technology but also suggest that 1D effects

240 strategies to maintain task demands and thus optimise the temporal performance of their movements.

241 by an extended tapering of doses is found to optimise the use of antibiotics.

242 nly based on adaptations through learning to optimise the use of intact end-effectors in patients wit

243 stand the spatial spread of this outbreak to optimise the use of the limited available vaccine stock.

244 We have optimised the IGNIS kit to quantify APO-F as a NAFLD bio

245 polymer and, by exploiting this interaction, optimised the production of tobramycin alginate/chitosan

246 hat this constrained chromatin configuration optimises the opportunity for the active enhancer to loc

247 for research that ensures accountability and optimises the use of available resources.

248 50-fold by gene modification, which included optimising the codon usage of the coding sequence to bet

249 epresents a novel tool for understanding and optimising the health efficacy of plant extracts.

250 resilience and strength of health systems by optimising the health workforce, and improve facility ca

251 good mechanical stability is challenging, as optimising the latter requires compromises regarding the

252 An example of such a challenge is optimising the performance of plasma fusion experiments.

253 vascular imaging in sizing the device and in optimising the scaffold implantation.

254 mpedance can be matched to the free space by optimising the surface resistance of the thin lossy meta

255 Optimising the timing of flowering contributes to succes

256 at when synchronising movements, individuals optimise their performance in terms of minimising variab

257 Optimising this balance remains hindered by our still li

258 The neural network is optimised through several tests with different numbers o

259 through membrane-feeding assays, which were optimised through the beginning part of phase one.

260 ctive spatial resolution and, in particular, optimised tissue contrast enabling semi-automated segmen

261 One resulting antibody is further optimised to achieve low-nanomolar binding affinity by i

262 cell and innate immunity pathways have to be optimised to boost the efficacy and immune memory of pro

263 dal imaging is one such option and should be optimised to comprehensively assess metastatic sites, di

264 gn of an optofluidic waveguide system can be optimised to enable simultaneous in-situ Raman spectrosc

265 idering how the deposition parameters can be optimised to ensure that the distribution of pores is ta

266 role on desired microextraction methods were optimised to obtain the maximum recovery of study analyt

267 Sample preparation conditions were optimised to prevent AgNPs oxidation and/or aggregation

268 with pulsed amperometric detection (PAD) was optimised to separate with precision, accuracy and high

269 Future research is required to optimise training, and assess clinical outcomes and cost

270 Multiple reaction monitoring (MRM) with optimised transitions and collision energies for each an

271 Codon usage thus evolved as a means to optimise translation on individual mRNAs, as well as glo

272 Biomarkers to optimise treatment choice for individual smokers might i

273 g randomised studies will continue to aim to optimise treatment for high-risk neuroblastoma.

274 The use of genetic algorithms to optimise treatment regimens enables an extensive search

275 ht into individualised outcome trajectories, optimising treatment selection, and targeted clinical tr

276 istence, pathogenesis, and immunity, and for optimising treatment.

277 In this modelling study, we optimised typical dietary patterns in an Indian populati

278 The main goal was to optimise UAE condition providing the highest recovery of

279 y of structured group psychoeducation versus optimised unstructured peer support for patients with re

280 f either structured group psychoeducation or optimised unstructured peer support.

281 act as signals that shape 3D root growth to optimise uptake.

282 collaborative, multidisciplinary approach to optimise use of antibiotics.

283 TDABC showed opportunities at HUM to optimise use of resources and reduce costs-for instance,

284 f the target analytes from fish samples were optimised using a Box-Behnken design method.

285 The influence of effective variables was optimised using Box-Behnken design (BBD) combined with d

286 polymers with high affinity for cocaine was optimised using molecular modelling.

287 mposition and extraction time) has been also optimised using response surface methodology with tomato

288 n extraction efficiency has been studied and optimised using response surface methodology.

289 Depolymerisation conditions were optimised using response surface methodology.

290 he 26 responses obtained were simultaneously optimised using the desirability method of Derringer and

291 Digestion of IGNIS prime peptides was optimised using trypsin and SMART Digest.

292 luticasone furoate with 25 mug vilanterol or optimised usual care and followed up for 12 months.

293 of serious adverse events when compared with optimised usual care.

294 -Fahn-Marin Tremor Rating Scale (TRS) during optimised VIM or VO lead stimulation at the end of the 3

295 tion might normalise retinal development and optimise vision.

296 Using an optimised wavelength divisional multiplexing scheme, we

297 The sequential stages optimised were: (1) the enzymatic hydrolysis of head car

298 three-dimensional organogenesis protocol was optimised whereby embryoid bodies were formed and patter

299 tracts were analysed with the HPLC-UV method optimised with 14 standard phenolics.

300 tem parameters of a spiral-filter press were optimised with the aim of producing a yellowish, cloudy