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1  seen early may not be real or may be overly optimistic.
2 ial stages; but the preliminary data make us optimistic.
3 acute renal failure, there are reasons to be optimistic.
4 ctations were lower, while patients remained optimistic.
5 increasing CO2 in the atmosphere, are unduly optimistic.
6            These results are probably overly optimistic.
7 epidemics during the ART era might have been optimistic.
8 uman studies suggest there are reasons to be optimistic.
9 l group was less than 9% even under the most optimistic a priori assumptions, and further trial accru
10   Parents of children with cancer are overly optimistic about chances of cure but not about other out
11                    Parents tend to be overly optimistic about cure when physicians have little confid
12                              I am moderately optimistic about improving predictions of large events f
13 assical Lewis structure nevertheless make us optimistic about the chances of detecting and even isola
14                         Not only are we more optimistic about the current state of the art in behavio
15 ford such high rate accelerations, making us optimistic about the prospects of designing more sophist
16 ding suggests that there is reason to remain optimistic about the therapeutic potential of these drug
17            In my view, however, they are too optimistic about the versatility of the paradigm and, mo
18 ding 29 (23%; 95% CI: 16, 30) with an overly optimistic abstract, 10 (8%; 96% CI: 3%, 13%) with a dis
19 confidence interval [CI], 70 to 74) with the optimistic analysis and 51% (95% CI, 49 to 52) with the
20                Corresponding figures for the optimistic analysis were 9%, 12%, 5%, and 7%.
21 lysis") or assumed negative for metastases ("optimistic analysis").
22 ernal age and performed with the use of both optimistic and conservative methods.
23 les over the last 10 years has led to a more optimistic and interventionist approach to the surgical
24        Fifth, he was perceived as cautiously optimistic and judiciously positive as he interacted wit
25 ely tree-species extinctions under published optimistic and nonoptimistic Amazon scenarios.
26 ee species in the Brazilian Amazon under the optimistic and nonoptimistic scenarios, respectively.
27 l of these common species persist under both optimistic and nonoptimistic scenarios.
28   Consequently, many expectations are wildly optimistic and over-estimate the speed and extent of the
29 producibility Project: Psychology data, both optimistic and pessimistic conclusions about reproducibi
30 ation areas with associated CO2 emissions in optimistic and pessimistic scenarios.
31 his review, the evidence for and against the optimistic and pessimistic viewpoints is discussed.
32 l assumptions, that is, intermediate between optimistic and pessimistic, is estimated to be approxima
33                                      All are optimistic and predict enormous positive impact on scien
34 ations of "5% chance of surviving" were more optimistic and showed substantial variability (median, 9
35 not only generous, but are also consistently optimistic and uncompromising.
36 nstruction of urinary diversion (ECUD) looks optimistic as favored by the patients and surgeons alike
37                                   Their very optimistic assessment is limited by statistical misconce
38 n average ratio less than one indicates more optimistic assessments with HRs.
39  <0.1%) did not occur by 30 years, even with optimistic assumptions about the linkage rate.
40 creening may be reasonable in younger men if optimistic assumptions consistent with existing observat
41                                    Under the optimistic assumptions in the primary analysis, the inci
42                                     Although optimistic assumptions would be required to achieve cost
43  of $2700/year of life saved, and may, under optimistic assumptions, achieve cost savings.
44                                         With optimistic assumptions, they can turn WWTPs into net ene
45                              Even under such optimistic assumptions, we find that the widespread depl
46  with using triple therapy first, even under optimistic assumptions.
47 style were less depressed than those with an optimistic attributional style and the nonpregnant group
48 ttributional style but not for those with an optimistic attributional style.
49 as an energy resource have often been overly optimistic, based in part on its very high methane conte
50   We suggest that their conclusion is overly optimistic because of a limited selection and interpreta
51 s, correlations, etc.) are frequently overly optimistic because the training sets are dominated by pa
52                                  Despite our optimistic belief that we would behave honestly when fac
53 actors that place parents at risk for overly optimistic beliefs about prognosis.
54                                     However, optimistic beliefs can at times appear surprisingly resi
55 ic of some enthusiasts focuses instead on an optimistic best-case scenario of the future of DNA scien
56         Both groups of patients exhibited an optimistic bias in that they considered themselves to be
57 y measure, with bootstrapping to correct for optimistic bias.
58 cy measure with bootstrapping to correct for optimistic bias.
59 fold cross-validation to limit the effect of optimistic bias.
60 nostications by surrogates arise partly from optimistic biases rather than simply from misunderstandi
61               The analysis also reveals that optimistic business-as-usual scenarios in the U.S. will,
62 wer C statistics, bootstrapping tended to be optimistic but with lower absolute and mean squared erro
63 nd the prospect of eradicating malaria is an optimistic, but reachable, target in the 21(st) century.
64                      Overall, the outlook is optimistic, but there is still some way to go.
65 ed from the National Research Council (2013) optimistic case.
66                                              Optimistic claims about the ability of recently proposed
67 were derived experimentally, leading to over-optimistic classifier performance estimates.
68                           Even with the most optimistic CO2 emissions scenario (Representative Concen
69 CD45RA+ CD4+ T cells are consistent with the optimistic conclusions that (i) renewal mechanisms have
70 gh risk for hemorrhage or meet the following optimistic criteria: prevent greater than 32% of major b
71 ning future space-based telescopes, but that optimistic definitions may be useful in interpreting the
72  of vital organs for transplant predicted by optimistic early estimates.
73 x traits; when applied to epilepsy, our most optimistic estimate suggests that at least 400 variants
74 oductivity is low, which lies in contrast to optimistic estimates based on regional statistical analy
75                            We find that with optimistic estimates for the stall stress of actin gel g
76  studies that may provide misleading, overly optimistic estimates of aging changes.
77                                    Even with optimistic estimates, few Atlanta MSM (15%) are projecte
78                                              Optimistic estimation of the C statistic is a frequent p
79 ents with advanced illness often have overly optimistic expectations about prognosis.
80                 Our findings indicate overly optimistic expectations about return home and unmet pall
81 ntial outcomes, and surrogates' unreasonably optimistic expectations seem to be potentially modifiabl
82 ower bound on that figure, obtained using an optimistic exposure scenario, was 0.3%.
83 ns and then they act according to their most optimistic forecast.
84           The primary factor differentiating optimistic from pessimistic projections was the degree t
85 )-approximately 3 times larger than the most optimistic GIF calculated here.
86 ep ahead of the beta-lactamases is an overly optimistic goal; the best that can be expected is to avo
87 atients; 2) surrogate stress and anxiety; 3) optimistic health expectations; 4) poor planning for med
88                      There are reasons to be optimistic, however, as emerging therapies have shown pr
89                           This may be overly optimistic, however, given that HIV-1 envelope proteins
90 diate grade sandpaper): a rat was classed as optimistic if it chose the bowl ordinarily associated wi
91 t-resuscitation patients but remained overly optimistic in do-not-attempt-resuscitation patients.
92 iour in the elevated plus maze and were more optimistic in the cognitive bias test.
93 n E efficacy, in hindsight, have been overly optimistic in their expectation that a vitamin could rev
94 ficantly pessimistic in patients without and optimistic in those with do-not-attempt-resuscitation or
95                              However, highly optimistic individuals exhibited reduced tracking of est
96                                The impact of optimistic interventions including immediate ART initiat
97 ces for biomarker development are published, optimistic investigators may not appreciate the statisti
98 ger in practice than we estimate here due to optimistic laboratory vehicle efficiency tests used in p
99 s, reflecting more pessimistic-like and less optimistic-like behavior, respectively.
100 s depressed individuals tend to adopt a less optimistic-like interpretation of ambiguous appetitive s
101 es that can resist invasion by defectors are optimistic (make high initial offers), generous (always
102 tients referred to a phase I clinic remained optimistic, many had discussed a living will, medical po
103 hysician as trustworthy vs 39 after the less optimistic message (P = .03).
104  More research is needed in structuring less optimistic message content to support health care profes
105 message type: 63 patients observing the more optimistic message ranked the physician as trustworthy v
106 ician discussing treatment information (more optimistic message vs less optimistic message) with a pa
107 information (more optimistic message vs less optimistic message) with a patient with advanced cancer.
108 optimistic vs an equally empathetic but less optimistic message.
109 and preferred physicians who provided a more optimistic message.
110                                              Optimistic methods assumed that patients who did not ret
111                                     The most optimistic mitigation of noise and contaminants would ma
112                                        Under optimistic model assumptions, oral pre-exposure prophyla
113 health care professionals in delivering less optimistic news.
114 IAPP) and leptin (LEP) analogues was once an optimistic option in treating obese animals and patients
115 om underpowered studies, resulting in overly optimistic or unwarranted conclusions.
116 d in the last year has continued the initial optimistic outlook for human papillomavirus vaccination
117 scular complications have resulted in a more optimistic outlook for people with diabetes.
118 ortant in MSP1-mediated immunity provides an optimistic outlook that a subunit MSP1 vaccine may be ef
119                           In 152 accurate or optimistic parents, we determined factors associated wit
120                                              Optimistic perception of illness and greater self-effica
121                                       A more optimistic perceptual set, despite equivalent objective
122                                              Optimistic, pessimistic, and baseline projections of the
123 ates of the probability of survival with the optimistic/pessimistic forecast given in the case.
124 outcomes are random, and we note examples of optimistic prediction in the literature.
125 will be more depressed after childbirth than optimistic pregnant teenagers.
126                           Although there are optimistic proponents for each strategy, the lack of wel
127  a problem, we developed a new method called Optimistic Protein Assembly from Reads (OPAR).
128 ross-validation procedure leads to an overly optimistic quality estimate, while the density-weighted
129 developed for three climate change scenarios-optimistic (RCP2.6), moderate (RCP4.5), and pessimistic
130 because adaptive theories are generally more optimistic regarding prospects for medical intervention
131 rk datasets, which lead to biased and overly optimistic reported performances.
132                               Finally, early optimistic reports of the use of bisphosphonates in juve
133 nity, high levels of activity, intelligence, optimistic resilience, and flexibility.
134                                   Relatively optimistic responses were more common among parents and
135  skepticism that U.S. studies will yield the optimistic results that have characterized the European
136 n of biofortified rice for white rice in the optimistic scenario (20 ppm and 70% substitution) decrea
137                                    Under our optimistic scenario (OPT) we find 15% and 47% adoption o
138                    However, even in the most optimistic scenario arrival screening will miss the majo
139 n approximately 37% loss rate even under the optimistic scenario.
140 -effective interventions, while only certain optimistic scenarios (low coverage of 5% and some or hig
141                                   Under more optimistic scenarios of reduced CO2 emissions, calcifica
142                                   Even under optimistic scenarios, we conclude that only a small frac
143                         Even if a relatively optimistic schedule of future capacity addition is met,
144                                 Even in such optimistic settings, no polymerization of RNA longer tha
145 ings show that the gene transfers provide an optimistic solution to the insufficiencies of the intrin
146                          One version offered optimistic survival forecasts; the other, pessimistic fo
147 study are significantly higher than the most optimistic survival rates in the medical literature, and
148      The majority of parents (61%) were more optimistic than physicians about the likelihood of cure.
149 d beliefs about the prognosis that were more optimistic than that of the physician, the most common r
150 ts conveying a high risk for death were more optimistic than the actual meaning (P < 0.001; generaliz
151 rly all of them (155 of 161 [96%]) were more optimistic than their oncologists.
152 to participate in a phase I trial being more optimistic than those declining phase I participation.
153  projections of food security are often more optimistic than what historical yield trends would suppo
154                                       We are optimistic that a better understanding of these changes
155                   There is good reason to be optimistic that approaches to block complement activatio
156 or phenylketonuria, experts in this area are optimistic that further public health benefits will foll
157                                    We remain optimistic that human therapeutic cloning is achievable
158            The results to date lead us to be optimistic that new candidate vaccines could soon be con
159 essful bariatric surgery, gives reason to be optimistic that novel precision medicines that mimic, en
160 modifiable disorder of motor control, we are optimistic that research will yield novel therapeutic av
161     From this pilot trial, we are cautiously optimistic that targeting the IL-6/IL-6R pathway could o
162                              Overall, we are optimistic that the big-data revolution will vastly impr
163 to ameliorate disease, there is reason to be optimistic that the dibenzofuran-based inhibitors will d
164 udy of neural circuits provide reasons to be optimistic that the field is headed in the right directi
165                  There is every reason to be optimistic that the wealth of knowledge about the molecu
166               Here, we present reasons to be optimistic that this new policy will be valuable for neu
167                    Numerous stakeholders are optimistic that this strategy will improve healthcare qu
168 duce CO2 abatement costs even under the most optimistic trajectories for improvements in fuel efficie
169 s that overestimate warming and gives overly optimistic uncertainty estimates.
170 s at higher risk for recurrence; however, an optimistic under-estimation of recurrence risk is a comm
171 e optimistic video as compared with the less optimistic video (median [interquartile range], 15 [5-23
172 er compassion scores after watching the more optimistic video as compared with the less optimistic vi
173 ctive interventions holds promise for a more optimistic view of neurocognitive status in later life.
174 his testing strategy can result in an overly optimistic view of the performance of an RNA-seq analysi
175  use of ineffective strategies and an overly optimistic view of the potential for ecosystem migration
176 "forest transition model" projects an overly optimistic vision of a future where increased agricultur
177  technologic and process innovations inspire optimistic visions.
178 ian compassion after being exposed to a more optimistic vs an equally empathetic but less optimistic
179 akes and is frequently interpreted in overly optimistic ways in the literature.
180 about efficacy of these mechanisms have been optimistic, we lack detailed analyses of their expected
181 ell within each group, but tended to be over-optimistic when predicting bilingual language outcomes:
182 sus for the future of surgery leadership was optimistic while recognizing that the demands of chairma
183 to this definition, the picture is much more optimistic, with perhaps greater than 20% of overweight/

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