ライフサイエンスコーパス: optimize

1 able" (i.e., they can be easily modified and optimized).

2 arameters affecting the SALLE procedure were optimized.

3 raction time and desorption conditions, were optimized.

4 o frequency power and argon flow rates) were optimized.

5 mponents required for LFA in milk system was optimized.

6 development and that these parameters can be optimized.

7 can rate of electropolymerization) have been optimized.

8 y and their performances are perhaps further optimized.

9 acy of such treatment is low and needs to be optimized.

10 Although similar functional screening of an optimized 30-site library (2.15 x 10(9) variants) reveal

11 d for identifying genomic modifications that optimize a complex phenotype through multiplex genome en

12 Therefore, we optimized a firefly luciferase complementation assay to

13 We then optimized a Gag immunoprecipitation procedure that permi

14 We have identified and optimized a novel series of high affinity KMO inhibitors

15 We designed and optimized a synergic system based on two bifunctional re

16 Optimizing a compound known to block the H3K27me3 site i

17 Planar photovoltaic devices from optimized ACI perovskite films yield a power-conversion-

18 expressed seed modules are first detected by optimizing an energy function via simulated annealing.

19 he stained manifold across which contrast is optimized and illumination is even.

20 Automated supported liquid extraction was optimized and implemented to simultaneously parallelize

21 correlation and variance of gray levels were optimized and then further confirmed on a validation set

22 ecause their activity and selectivity can be optimized and understood mechanistically using the famil

23 t promising concepts in nuclear medicine for optimizing and individualizing treatments for many cance

24 This model is a valuable tool in optimizing and planning experiments without the need for

25 nfluent monolayers on the sensor slides were optimized, and neurotransmitter exocytosis was evoked by

26 ch as writing pressure and speed, were first optimized, and the electrochemical performance of these

27 A novel extraction method was developed, optimized, and validated for the elemental analysis of o

28 the mass-escalation study indicates that an optimized antagonist mass might further improve the safe

29 The objective was to optimize anthocyanins extraction from black bean coats a

30 These findings are relevant for optimizing antiretrovirals used for biomedical HIV preve

31 estive and Kidney Diseases-led consortium to optimize approaches for the isolation, expansion, and di

32 zole copolymer) is combined with a carefully optimized architecture to satisfy the electrical require

33 ity varied with the Cu(I) availability in an optimized assay solution for either environment, demonst

34 pcJ-1 approximation applied to conformations optimized at DFT/B3LYP/6-311++G** level supported the in

35 ding and perceptual decoding are matched and optimized based on identical assumptions about the stati

36 the neural network, which are automatically optimized based on training images.

37 could separate the selection for replication-optimizing beneficial mutations during lysis from sequen

38 that MRSA-screening-directed prophylaxis may optimize benefits while minimizing harms in this selecte

39 d energy levels, and high hole mobility from optimized BHJ morphology afford a very high power conver

40 minimum rim area (BMO-gMRA) and sector-wise optimized BMO-minimum rim area (BMO-MRA).

41 DNA immunization efficacy was optimized by i.m. delivery via electroporation, yet it r

42 uboptimal CD8 T cell in old organisms can be optimized by manipulating Ag presentation, with implicat

43 SPA-LN is optimized by maximizing both the affinity and specificit

44 y evolve via a low-affinity complex which is optimized by modulating direct interactions as well as d

45 om a complex chocolate-based food matrix was optimized by testing different temperatures, extraction

46 roughout the dark period in K. fedtschenkoi, optimizing CAM-associated dark CO2 fixation, malate accu

47 T tracers and how they may be used to better optimize cancer therapy.

48 ories, thereby decreasing adverse events and optimizing cancer treatment.

49 interplay between these disease processes to optimize care for pediatric patients with these conditio

50 T cells transduced with the optimized CD200R-CD28 IFPs exhibited enhanced proliferat

51 ate further research and development of more optimized CEP systems.

52 t incorporates all diagnostic categories and optimizes classification by selectively combining a subs

53 rging targeted treatments, and strategies to optimize clinical trials to efficiently and effectively

54 tic interventions and precision medicine for optimizing clinical care of these individuals.

55 Compared to the benchmark Pt/C catalyst, the optimized Co@C-800 (carbonized at 800 degrees C) exhibit

56 Effect of integrating optimized combination of pretreatment with packaging on

57 e were sequentially perturbed to identify an optimized combination of small molecules that yielded ap

58 xis, elucidate the underlying mechanism, and optimize conditions to achieve DNA concentration factors

59 At optimized conditions (FLMs consisted of 1-pentanol and e

60 Here we optimized conditions for liquid chromatography coupled t

61 of the MsrQ protein from Escherichia coli We optimized conditions for the overexpression and membrane

62 Under minimally optimized conditions, a photocurrent density of as high

63 At optimized conditions, a stable POS production with 22.0g

64 Under optimized conditions, the method exhibited a linear dyna

65 Under the optimized conditions, the proposed method showed good li

66 0.12 mg L(-1), and LOQ = 0.38 mg L(-1) under optimized conditions.

67 a mixture of tetrahydrofuran and water under optimized conditions.

68 In conclusion, the LepNP85 with optimized conjugation chemistry is a promising candidate

69 eated fusions of both stability- and potency-optimized CTLA4 moieties with human Fc variants conferri

70 ssumptions need to be understood in order to optimize data-driven decision-making.

71 can be realized in a controllable manner by optimizing dealloying conditions.

72 he uniform distribution is very close to the optimized design.

73 tionship to dry eye is important in order to optimize diagnosis and treatment algorithms.

74 off ratio exceeding 10(6) are achieved under optimized doping conditions.

75 To enable optimized dosing, the use of customized dosing regimens

76 Even though both MAGNA++ and DynaMAGNA++ optimize edge as well as node conservation across the al

77 We then introduced the optimized-enhanced aromatic sequons into other glycoprot

78 l in device applications, it is essential to optimize epitaxial growth for the precise control of nan

79 It is found that under optimized experimental condition, DPA-SCP with white lig

80 Under optimized experimental conditions, the probe detects bil

81 detection of 0.21mumolL(-1) for TBHQ, under optimized experimental conditions.

82 ere to apply response surface methodology to optimize fat-soluble vitamin loading in re-assembled cas

83 zipping assays on hairpin substrates with an optimized flat free energy landscape containing all bind

84 molecular wire-based voltage sensors with 2P-optimized fluorophores for imaging voltage in intact bra

85 rum of reasons, such as evading predators or optimizing food prospection.

86 Using force spectroscopy optimized for 1-microsecond resolution, we reexamined th

87 ite matter connectivity becomes increasingly optimized for a diverse range of predicted dynamics in d

88 timal solution requires a method that may be optimized for available therapies and is designed for ex

89 n coupled with a conveyor belt drive that is optimized for crystallography and spectroscopy measureme

90 with performance approaching that of devices optimized for each material individually.

91 microfluidic device, the design of which was optimized for each printer: fused deposition molding (FD

92 ited to off-label use of corticosteroids not optimized for esophageal delivery.

93 d ER-targeted low-affinity Ca(2+) indicators optimized for examining axonal ER Ca(2+).

94 s of a segregated highway - suggesting it is optimized for function-specific coordination between bra

95 The process was optimized for hydrolysis of MP into p-nitrophenol (PNP).

96 ds efficient syntheses using building blocks optimized for interactions with subtype-specific residue

97 Parameters optimized for maximum recovery of gingerols and [6]-shog

98 The adaptive policy optimized for middle-income resource settings yields 0.0

99 Using anatomical MRI optimized for myelin contrast within gray matter, we als

100 ionTracker is a quantitative imaging package optimized for oncology clinical trial workflows.

101 to traditional analysis techniques that were optimized for other data types.

102 VDJPipe is a high-performance tool that is optimized for pre-processing large immune repertoire seq

103 in developing enzymes with cleavage patterns optimized for producing paCOS with defined patterns of a

104 red to enhance trans-activation capacity and optimized for simple screening assays with luciferase or

105 the first time that experimental conditions optimized for SRM 955c (caprine blood) are not valid for

106 ughput next-generation sequencing techniques optimized for the capture of HML-2 expression, we charac

107 The HS-Trap GC-FID method was optimized for the parameters: thermostatting time and te

108 class of small molecules that may be further optimized for the repair of CNS damage.

109 search should evolve to define novel methods optimized for the role of cardiovascular imaging for det

110 Compounds were optimized for their activity and selectivity over TLR8.

111 r, and developmental biology 402 (MCDB 402)] optimized for their clonal growth in minimal serum, they

112 f samples, and most analytical pipelines are optimized for these smaller studies.

113 Generation of the CARS signal is optimized for water imaging with broadband excitation.

114 We describe optimized fragmentation schemes and data analysis strate

115 sequence in the HIV-1 genome with two codon-optimized gag sequences and found that such substitution

116 r structure-property relations is crucial to optimize gamma but requires state of the art measurement

117 in the lungs and the genital tract with the optimized GC-coated LPN adjuvant upon nasal immunization

118 s were consistently enriched in highly codon-optimized genes of generalist but not specialist species

119 alancing protein expression is critical when optimizing genetic systems.

120 d be elicited more efficiently with suitably optimized GP immunogens.

121 urrent review also presents perspectives for optimizing GWAS design and analysis.

122 on, apelin-13 infusion delivers distinct and optimized hemodynamic support (including positive fluid

123 ing streamlining organ allocation practices, optimizing HIV-infected donor and recipient selection, m

124 filing data as a means to better predict and optimize humoral responses in genetically diverse human

125 end, we have generated a mouse line with an optimized hybrid voltage sensor (hVOS) probe within a lo

126 rop in absolute sensitivity when compared to optimized immunofluorescence staining.

127 The nanoparticle design was optimized in a highly systematic way by using a quality-

128 x agitation time and complexation time) were optimized in a univariate way.

129 ectation that investment in immunity will be optimized in anticipation of disease risk.

130 upports and the immobilization procedure was optimized in batch mode, by evaluating protein loading,

131 of the photolithographic processes have been optimized in order to overcome all the issues of the tec

132 m, since the number of variables needs to be optimized increases quadratically with the scale of GRNs

133 ion about the commonly adopted strategies to optimize individual TE properties is presented.

134 is a promising strategy that can be used to optimize inflammatory bowel disease therapeutics.

135 used in artificial communication networks to optimize information throughput at the group level.

136 y, theory, and environmental manipulation to optimize intervention approach.

137 Efforts to optimize iron status should keep these findings in view.

138 More work is needed to optimize its dosing to minimize adverse events, such as

139 y, accuracy, and safety of PLB are needed to optimize its use.

140 nditions, and repeated cross-validation that optimizes its discriminant power.

141 The aim of this work was to optimize labeling of (68)Ga-PSMA(HBED) using the efficie

142 relationship (SAR) analysis, we obtained an optimized lead compound (38u) that represses breast canc

143 Response surface methodology was applied to optimize lentil fermentation and study its effects on ge

144 Optimized ligands from the database were virtually scree

145 nanoparticles in vivo, an essential step for optimizing light-induced, nanoparticle-based therapies.

146 ng a fluorescent reporter system in order to optimize linker stability for mitochondrial release.

147 we aimed to identify a therapeutic target to optimize lung preservation leading to successful lung tr

148 Using this approach, an optimized macrocyclic peptide inhibitor (HL2-m5) was obt

149 gical battery and neuroimaging that included optimized magnetic resonance spectroscopy to measure ant

150 at elevated tidal range and bed shear stress optimized mangrove development along tide-influenced tro

151 hrough discovering novel quality attributes, optimizing manufacturing, and screening drugs/biomateria

152 with actionable information to help further optimize medications and improve outcomes.

153 The optimized method employed only 1g of silica gel for disp

154 The optimized method is simple, mild, and highly regioselect

155 The optimized method was applied for the determination of Cd

156 The optimized method was fully validated, resulting in accep

157 action protocols were evaluated, and for the optimized method, absolute extraction recoveries ranged

158 We used contrast-optimized micro X-ray computed tomography (mCT) to trace

159 Outcome parameters included BMO-globally optimized minimum rim area (BMO-gMRA) and sector-wise op

160 attachment status of kinetochores therefore optimizes mitotic duration by controlling the balance be

161 udy provides a novel therapeutic strategy to optimize MK-1775 treatment efficiency in lung cancers.

162 Guided by the structures, an optimized molecule was generated with differential inhib

163 ed actions but rather a single movement that optimizes motor costs.

164 op AcTakines (Activity-on-Target cytokines), optimized (mutated) immunocytokines that are up to 1,000

165 actors affecting the slurry preparation were optimized: nature and concentration of acid solution and

166 ontribution to the improvement is due to the optimized NBC combination of the complementary informati

167 Using methyl transverse relaxation-optimized NMR spectroscopy, we demonstrate that only thr

168 ; 2) used deformation fields obtained during optimized nonlinear registrations to compute nonlinear t

169 Optimizing nsPEF delivery protocols to induce sensitizat

170 Conclusion With regard to optimizing nucleic acid yields in CT-guided lung core ne

171 ransmittance spectrum of the filter-which is optimized numerically by maximizing SNR.

172 Upon excitation at 407 nm, the composition-optimized NYS:0.10Sm(3+) exhibited a high quantum effici

173 Automated radiosynthesis of (18)F-FCP was optimized on the basis of manual synthesis procedures.

174 These data will guide practices to optimize opioid prescribing after surgery.

175 o understand and control protein dynamics to optimize or inhibit function.

176 e suggestions on necessary future studies to optimize organ transplantation for older people.

177 LD cycles of TiO2 growth are found to be the optimized parameter toward capacity, Coulombic efficienc

178 teps, which could be fruitfully targeted for optimized PE consumption by R. ruber.

179 amicarbalide that led to two compounds with optimized pharmacological and antiparasitic properties.

180 d on this finding, we discuss strategies for optimizing photon absorption via modulation of the struc

181 lter their morphology and/or biochemistry to optimize photosynthetic efficiency and productivity acco

182 The margin for optimizing polychemotherapy is wide, but a quantitative

183 The optimized PPA/P2 O5 medium is a mild acid that is not on

184 on protein (PrP(C)) to selectively propagate optimized prion conformations from larger ensembles gene

185 Optimized probe 2 (XO44) covalently modified up to 133 e

186 s combined with long-read DNA sequencing, we optimize productivity by 50-fold to produce bioactive yi

187 tant adjustment of the FIT cut-off levels to optimize program performance.

188 drug reaction assessment and rechallenge to optimize prophylaxis in this patient cohort.

189 t vaccination strategies will be required to optimize protection mediated by T cells recognizing anti

190 Here we describe an optimized protocol for simultaneous dual-channel two-pho

191 We report optimized protocols for radiolabeling liposomes with (52

192 nts has emerged as an intriguing approach to optimize Pt catalytic performance.

193 for high ee's, ortho-tert-butoxyaniline our optimized reaction (i.e. solvent, temperature and cataly

194 Under the optimized reaction conditions, a broad range of nitrogen

195 uiring more than three backbone residues for optimized recognition.

196 e a standardized baseline for future work to optimize recommended diets further.

197 asisHLB cartridges were connected in-line to optimize recovery, and the eluted samples from each cart

198 To optimize removal of organic micropollutants from the wat

199 king them uniquely equipped to normalize and optimize response sensitivity across distant receptive f

200 c Marker-Adjusted Personalized Therapy Trial Optimizing Risk Assessment and Therapy Response Predicti

201 r functional information-processing loops in optimizing saccade generation in dynamic environments.SI

202 We present an optimized sample-processing pipeline for analysis of the

203 The optimized sensing probe possesses a remarkably good sens

204 s, using a variable chemical spacer shown to optimize sensor response.

205 ng the high-affinity interaction between the optimized sequence on hCD2ad and a human oligosaccharylt

206 ze sensitivity and cost-efficiency, we first optimized several parameters, such as integrin-immobiliz

207 Optimizing sgRNA design to improve the efficiency of tar

208 ions of Czech Republic, were achieved, using optimized solvent extraction and liquid chromatography c

209 Li and competing ions demonstrates that our optimized sorbents can achieve a recovery efficiency of

210 The aim of this study was to optimize specific and total activity for (177)Lu-PSMA-61

211 PLP-dependent enzymes optimize specific chemical reactions by modulating the e

212 hm was constructed using urine RNA assays to optimize specificity while maintaining 95% sensitivity f

213 We optimized specimen processing to maximize the limit of d

214 Relative to unmodified peptides, optimized stapled peptides exhibit increased structural

215 scular disease (ASCVD), guidelines recommend optimizing statin treatment, and consensus pathways sugg

216 In this protocol, we present the optimized, step-by-step procedure for generating reprodu

217 imits of this information storage system and optimize strategies to minimize those limitations.

218 crystal and density functional theory (DFT)-optimized structures, which binds choline in a unique du

219 However, little work has been done to optimize such transplantation.

220 In an optimized system, As(III) was reduced and deposited as A

221 e of spatially explicit stochastic models to optimize targeting of surveillance and control resources

222 iance structures for the upstream cells that optimize the ability of information to propagate through

223 Animals employ active touch to optimize the acuity of their tactile sensors.

224 ved phospho-regulatory feedback mechanism to optimize the balance of growth and stress responses.

225 that natural variation in repeat numbers may optimize the chance for survival.

226 guide preoperative mapping of tumor borders, optimize the day of surgery, and identify occult lesions

227 y mimic the complexity of cell membranes and optimize the efficiency of delivery vesicles, controllin

228 transfer and utilization of light energy to optimize the efficiency of photosynthesis and avoid phot

229 Researchers have strived to optimize the electromechanical structures and to design

230 he integrated cheminformatics algorithm will optimize the extracted biological data using in vitro-in

231 amiltonian control is generally necessary to optimize the Fisher information.

232 cious vaccine candidate; when we are able to optimize the immunization regimen (dose, interval betwee

233 r, we utilize this structural information to optimize the inhibitor structure to achieve a Ki of 110

234 In our attempt to optimize the lead HIV-1 entry antagonist, NBD-11021, we

235 rom the plant Abies grandis was expressed to optimize the limonene biosynthetic pathway.

236 on using ultrafast spectroscopy as a tool to optimize the material bandgap without altering ultrafast

237 ove patient acceptance and adherence, and to optimize the patient-provider relationship.

238 icable as part of a multifaceted approach to optimize the production of HSPCs from human PSCs.

239 This research was to optimize the UAE conditions for maximum mandarin peel ex

240 ific drugs and for patient stratification to optimize the use of available therapies.

241 is computational problem, it is important to optimize the variant analysis workflow and the used anal

242 ration into micro-total analysis systems, we optimized the production of a low-cost polymer based mic

243 Here, we optimized the protein misfolding cyclic amplification (P

244 We first optimized the size, surface modification [rifampicin (RF

245 In this study, we optimized the Xpert EBOV assay for semen samples by addi

246 t includes a secondary "targeting" step that optimizes the bias-variance tradeoff for the target para

247 r knowledge, this is the first solution that optimizes the execution of the workflow using computatio

248 ield couplings of the Fano resonances, hence optimizing the associated localized electric field inten

249 ular flexibility was shown to play a role in optimizing the binding between receptors and ligands.

250 hroughout and beyond the diauxic shift, thus optimizing the coordination of nucleocytosolic acetyl-Co

251 strated the applicability of this toolkit by optimizing the expression of a challenging but industria

252 After optimizing the feature sets via cross-validation, the tr

253 ms, suggesting a role of IgG1 Fc N-glycan in optimizing the interface with the Fc receptor for effici

254 Optimizing the microenvironment and understanding drug e

255 Here, we describe a mechanism optimizing the performance of the dim-light channel of v

256 ld population amidst climate change requires optimizing the reliability, resource use, and environmen

257 erage improved efficiency by refactoring and optimizing the source C code of QUBIC; and (ii) a set of

258 tals are considered, which are important for optimizing the textural characteristics as well as the f

259 tions and then minimizes stitching errors by optimizing the translations within a (4r)(2) square area

260 ss the reliability of learned information to optimize their behaviour.

261 rcial cantilevers with a focused ion beam to optimize their properties for SMFS.

262 s these advances and provides suggestions to optimize therapy for patients with BOS after HCT.

263 ctory Hodgkin lymphoma (HL) is essential for optimizing therapy with risk-adapted approaches.

264 asy to be combined with other approaches for optimizing thermoelectric performance.

265 tworks and they may be structured in part to optimize this task.

266 We optimized this mobile SEF system by tuning the metal-fil

267 the presence of those perturbations and (ii) optimizing those flexibilities can be a possible design

268 The optimized three-dimensional molybdenum disulfide foam wi

269 e plasma system with oxygen gas flow and the optimized time for treatment was 1 min.

270 well exceeding the theoretical limit of the optimized time-frequency filtering.

271 This novel transformation has been optimized to 30 mol% p-toluenesulfonic acid (p-TSA) in t

272 ht harvesting and thus how these systems are optimized to capture sunlight under physiological condit

273 NADH ED-FRAP parameters were optimized to deliver 23.8 mJ of photobleaching light ene

274 Here, we created a novel paradigm optimized to dissociate the subtypes of reward-predictio

275 a polyacrylate (PA) SPME sorbent coating was optimized to enhance the extraction performance.

276 l survival and proliferation and they can be optimized to induce cell differentiation and maturation.

277 The mobile phase composition was optimized to maintain the proteins studied in native con

278 The 100 bp ladder fragments have been optimized to migrate appropriately on both agarose and n

279 n enhancement, on-bead trypsin digestion was optimized to obtain efficient and reproducible peptide r

280 The bioelectrochemical assay was optimized to obtain high sensitivity and the method was

281 The resulting maleimide scaffold was optimized to subnanomolar potency while retaining good p

282 nonymous substitutions have been selected to optimize translation rates at specific locations within

283 To optimize translation, we need to assess the effect of ex

284 ores should be a focus in future research to optimize treatment strategies to reduce a negative impac

285 l stroma post CXL, and promises to establish optimized treatment modalities in patients with KC.

286 y eligibility required that after 4 weeks of optimized treatment, the patients still have more than 1

287 ce and/or further 20% N saving compared with optimized urea-N rate (150 kg N ha(-1), based on N requi

288 elines orchestrating the entire workflow and optimizing usage of available computational resources.

289 The effective parameters were optimized using a central composite design.

290 cy for omega-3 (n-3), and its production was optimized using a response surface method.

291 composition and measurement conditions were optimized using an experimental design.

292 t software-chosen molecular descriptors, was optimized using CCS values of 205 small molecules and va

293 e volume fraction (f) of graphene in ZnO was optimized using simulation of electric field intensity.

294 This optimized version of our original Structure-seq method i

295 hese factors can be effectively explored and optimized via simulation prior to deployment in the MRI

296 to have enhanced signal-to-noise ratio, thus optimizing visualization of small subcortical structures

297 n D3 may therefore be a preferential form to optimize vitamin D status within the general population.

298 t in endogenous analgesia, we used brainstem optimized, whole-brain imaging to record responses to co

299 hitecture of the oligonucleotide needs to be optimized with a combination of sugar, backbone, nucleob

300 The optimized yogurt had 79% acceptability index, indicating