1 The other isolate was uniformly resistant to optochin.

2 aboratory by demonstrating susceptibility to optochin.

3                Resistant strains had MICs of optochin 4-30-fold higher than susceptible strains, belo

4 holate tube test, 100 and 99%, respectively; optochin, 99 and 98%, respectively; and Gram Positive Id

5 6) for spontaneous mutation to resistance to optochin and was 10- to 200-fold lower in the absence of

6 that were susceptible to ethylhydrocupreine (optochin) and therefore were presumed to be pneumococci

7    alpha-Hemolytic streptococci resistant to optochin, particularly invasive isolates, should be test

8 and 1998, 4 pneumococcal isolates exhibiting optochin resistance were recovered from patients at Chil

9 osure to antimalarial drugs and evolution of optochin resistance.

10               The 11 remaining isolates were optochin resistant, and 6 of these were bile soluble.

11 4 isolates consisted of mixed populations of optochin-resistant and -susceptible organisms.

12                              In the RM, four optochin-sensitive alpha-hemolytic colonies resembling p

13 gentamicin and screened for alpha-hemolysis, optochin sensitivity, and bile solubility.

14  using a new and expanded group of antisera, optochin susceptibility and bile solubility tests, and a

15 is of three differentiating characteristics: optochin susceptibility, bile solubility, and agglutinat

16                                     Although optochin susceptibility, bile solubility, and Quellung t

17 umococci but cannot be resolved from them by optochin susceptibility, bile solubility, or the presenc

18 e, San Diego, CA), the bile solubility test, optochin susceptibility, colony morphology, and the caps

19 ion with Omni serum, and 87.9% and 59.3% for optochin susceptibility.

20            Of the 52 isolates, 38 (73%) were optochin susceptible, were psaA and ply positive, and co