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1 , but no differences in nucleus accumbens or orbitofrontal activation, compared with inexperienced tr
2 elf-esteem was associated with the bilateral orbitofrontal activity during evaluation of one's own po
3 ficantly decreased mid-insula, amygdala, and orbitofrontal activity while attending to interoceptive
4 ing behaviors in children; and indicate that orbitofrontal-amygdala network properties may influence
5 nce, with significant underactivation in the orbitofrontal and anterior cingulate cortices compared w
7 ce of increased striatal-anterior prefrontal/orbitofrontal and decreased striatal-dorsal anterior cin
9 BPD exhibited higher activity in the lateral orbitofrontal and dorsolateral prefrontal cortices compa
10 Here we show that different regions of the orbitofrontal and medial prefrontal cortex make distinct
11 lly, the learning-induced pattern effects in orbitofrontal and perirhinal cortex predicted the magnit
12 f inferior frontal gyrus, alongside insular, orbitofrontal and temporal cortex in our patient cohort.
17 egory codes within the perirhinal, piriform, orbitofrontal, and insular cortices suggests that these
18 eferentially starts in the precuneus, medial orbitofrontal, and posterior cingulate cortices, i.e., s
19 istration into the prelimbic, medial/ventral orbitofrontal, and ventrolateral orbitofrontal cortex, m
20 al circuits-the caudate, thalamic, striatal, orbitofrontal, anterior cingulate and dorsolateral regio
22 (MO), ventral (VO), and ventrolateral (VLO) orbitofrontal areas and the caudal portion of lateral or
23 The reduced functional connectivity in left orbitofrontal-both thalamic regions with suicidal ideati
24 he OFC, the agranular insula and the lateral orbitofrontal cortex (AI-OPNs and LO-OPNs, respectively)
25 y excitotoxic lesions of either the anterior orbitofrontal cortex (antOFC) or ventrolateral prefronta
28 ionally distinct learning signals in lateral orbitofrontal cortex (lOFC) and the dopaminergic ventral
30 t work in macaques has suggested the lateral orbitofrontal cortex (lOFC) is relatively more concerned
31 sed if pharmacologic inactivation of lateral orbitofrontal cortex (lOFC) or DBS of the ventral striat
32 reward values are represented in the medial orbitofrontal cortex (mOFC) at the time of choice [7-9].
33 s or chemogenetic inactivation of the medial orbitofrontal cortex (mOFC) in rats induces failures in
34 Contrary to IL and AI, we found that medial orbitofrontal cortex (mOFC) projects densely through dor
35 overlapping valuation signals in the medial orbitofrontal cortex (mOFC) were observed for the three
36 a given reward, or "reinforcer." The medial orbitofrontal cortex (mOFC), a subregion of the ventrome
37 us accumbens, amygdala, anterior insula, and orbitofrontal cortex (n = 18 had analyzable fMRI data).
38 46, n = 2), the vLPFC (A46v, n = 2), and the orbitofrontal cortex (OF; n = 2) were placed for confirm
39 critical for odor memory and perception- and orbitofrontal cortex (OFC) - a region involved in revers
41 Recent studies have challenged the view that orbitofrontal cortex (OFC) and amygdala mediate flexible
42 pERK expression in medial prefrontal (mPFC), orbitofrontal cortex (OFC) and areas in striatum and amy
43 bregions of the frontal cortex including the orbitofrontal cortex (OFC) and dorsomedial prefrontal co
44 presentations of identity-specific reward in orbitofrontal cortex (OFC) and identity-general reward i
45 multaneously decrease neural activity in the orbitofrontal cortex (OFC) and increase activity in NAC
46 ned the activation patterns of cue-activated orbitofrontal cortex (OFC) and nucleus accumbens (NAc) s
47 omic and functional connectivity between the orbitofrontal cortex (OFC) and the amygdala in mice.
48 STATEMENT Dysfunctional interactions between orbitofrontal cortex (OFC) and the amygdala underlie sev
50 parallel, fMRI cross-adaptation in the right orbitofrontal cortex (OFC) and the left anterior tempora
52 ateral nucleus of the amygdala (BLA) and the orbitofrontal cortex (OFC) are involved in behavior that
53 h studied, the role of prominent inputs from orbitofrontal cortex (OFC) are less well understood.
54 enced value representations within the human orbitofrontal cortex (OFC) are thought to be organized t
57 including the basolateral amygdala (BLA) and orbitofrontal cortex (OFC) can accompany these same diso
58 lations of neurons and HGA recorded from the orbitofrontal cortex (OFC) encode similar information, a
59 ing economic decisions, offer value cells in orbitofrontal cortex (OFC) encode the values of offered
60 urface expression assays using both mPFC and orbitofrontal cortex (OFC) from individual EC or IC rats
67 to either medial prefrontal cortex (mPFC) or orbitofrontal cortex (OFC) immediately prior to performa
69 tly recorded local field potentials from the OrbitoFrontal Cortex (OFC) in five human subjects perfor
70 utions of the basolateral amygdala (BLA) and orbitofrontal cortex (OFC) in rats to learning under exp
71 reased stress-induced activity in the medial orbitofrontal cortex (OFC) in the high CA group (p<0.01,
72 parate lines of research have implicated the orbitofrontal cortex (OFC) in the judgment of social tra
74 directed behavior.SIGNIFICANCE STATEMENT The orbitofrontal cortex (OFC) is critical for goal-directed
82 nd recorded from dorsomedial PFC (dmPFC) and orbitofrontal cortex (OFC) neurons while they were freel
83 the activity of neurons in the amygdala and orbitofrontal cortex (OFC) of monkeys during a Pavlovian
84 rk identified three groups of neurons in the orbitofrontal cortex (OFC) of monkeys engaged in economi
85 monkeys with bilateral lesions of either the orbitofrontal cortex (OFC) or the amygdala could learn a
87 reward contingencies, with the medial versus orbitofrontal cortex (OFC) subregions contributing diffe
89 orm of cognitive flexibility mediated by the orbitofrontal cortex (OFC) that we have used previously
90 from the anterior cingulate cortex (ACC) and orbitofrontal cortex (OFC) to assess network similaritie
91 ed repetitive element loci (RE) in the human orbitofrontal cortex (OFC) using directional RNA sequenc
92 The caudate has dense connections with the orbitofrontal cortex (OFC) via the frontostriatal loops,
95 One hedonic hotspot was found in anterior orbitofrontal cortex (OFC), and another was found in pos
96 and ventral striatum, left insula and middle orbitofrontal cortex (OFC), and right insula projecting
98 er cortical gray matter than controls in the orbitofrontal cortex (OFC), anterior and posterior cingu
99 Other frontal regions, in particular the orbitofrontal cortex (OFC), are critical in directing be
100 entral medial prefrontal cortex (vmPFC), and orbitofrontal cortex (OFC), brain regions implicated in
101 restingly, we found that inactivation of the orbitofrontal cortex (OFC), but not the dorsal or ventra
103 vity in both medial and lateral parts of the orbitofrontal cortex (OFC), only the lateral OFC represe
104 LA-driven intra-amygdaloid paths and concise orbitofrontal cortex (OFC)-CeA-driven extra-amygdaloid c
118 ng value-guided learning, whereas the medial orbitofrontal cortex (often referred to as ventromedial
119 ulated the food-related signal in the medial orbitofrontal cortex (P=0.01) and nucleus accumbens (P=0
120 The primate amygdala projects to posterior orbitofrontal cortex (pOFC) directly and possibly indire
121 mygdala sends dense projections to posterior orbitofrontal cortex (pOFC) in pathways that are critica
122 irectional dialogue of the primate posterior orbitofrontal cortex (pOFC) with the amygdala is essenti
123 into occipital cortex (left hemisphere) and orbitofrontal cortex (right hemisphere); bilateral precu
124 gative connectivity between the amygdala and orbitofrontal cortex (thresholded at z > 1.70, P < .05).
125 significantly correlated with TSPO VT in the orbitofrontal cortex (uncorrected Pearson correlation r
126 We find that anticipatory signals in the orbitofrontal cortex about upcoming choice increase over
128 study provides evidence for the key role of orbitofrontal cortex activity in choice behavior and sho
129 associated with nucleus accumbens and medial orbitofrontal cortex activity, whereas distress was pref
131 ted hyperconnectivity in a network involving orbitofrontal cortex along with a less resilient global
132 taste, olfactory, and flavor stimuli in the orbitofrontal cortex and a region to which it projects,
136 y, we examined activity of single neurons in orbitofrontal cortex and in ventral and dorsal striatum
137 and RSFC between the midbrain and striatum, orbitofrontal cortex and insula in methamphetamine-depen
138 ation revealed that the two regions studied, orbitofrontal cortex and nucleus accumbens, are not sequ
139 and similar effects were found in the right orbitofrontal cortex and right inferior frontal gyrus.
140 and functional abnormalities in left lateral orbitofrontal cortex and right supplementary motor area,
141 he anterior and middle cingulate cortex, the orbitofrontal cortex and the medial and ventromedial sup
144 ckwards toward the lost option, cells within orbitofrontal cortex and ventral striatum represented th
145 TEMENT The lateral and medial regions of the orbitofrontal cortex are cytoarchitectonically distinct
146 dentified the ventromedial prefrontal cortex/orbitofrontal cortex as the main structure in this circu
147 functional connectivity involved the medial orbitofrontal cortex Brodmann area 13, which is implicat
150 eased functional connectivity of the lateral orbitofrontal cortex Brodmann area 47/12 is related to d
151 t the functional connectivity of the lateral orbitofrontal cortex Brodmann area 47/12 with these thre
153 late cortex and striatal-anterior prefrontal/orbitofrontal cortex circuits was significantly associat
154 es, as well as between the right amygdala to orbitofrontal cortex connectivity and levels of craving.
156 teral prefrontal cortex and amygdala-lateral orbitofrontal cortex coupling were shown in male BPD pat
157 ined the role of parvalbumin interneurons in orbitofrontal cortex during reversal learning by recordi
158 he degree of both affective processes in the orbitofrontal cortex during self-reflection and cognitiv
159 whole, showed hyperactivation in the medial orbitofrontal cortex during the acquisition of avoidance
161 ts of the ARs in the caudate nucleus and the orbitofrontal cortex for all of the subjects, and a non-
162 e performed with (123)I-PIP using postmortem orbitofrontal cortex from cognitively normal and AD huma
163 hometry analyses demonstrated greater medial orbitofrontal cortex gray matter intensity in controls t
165 g of the functions of different parts of the orbitofrontal cortex in emotion helps to provide new ins
167 pecifically, BOLD was higher in the inferior orbitofrontal cortex in response to savory food cues.
170 nt avoidance were seen immediately, those of orbitofrontal cortex inactivation were delayed and their
171 r show that this property of CINs depends on orbitofrontal cortex input and is correlated with choice
172 task as well as from other sources, that the orbitofrontal cortex is a critical node in the neural ci
175 bstantial number of studies showing that the orbitofrontal cortex links events to reward values, wher
176 credit assignment, whereas damage to medial orbitofrontal cortex meant that patients were more likel
179 extracellular recordings in the striatum and orbitofrontal cortex of mice that learned the temporal r
180 d large-scale recordings in the striatum and orbitofrontal cortex of mice trained on a stimulus-rewar
182 processing of affect; nucleus accumbens and orbitofrontal cortex of the reward circuit; anterior ins
184 once the stimulus is presented suggest that orbitofrontal cortex plays a role in transforming immedi
185 Here we show that basolateral amygdala to orbitofrontal cortex projections are required for expect
186 bjects were presented, neuronal ensembles in orbitofrontal cortex represented distinct value-based sc
190 facilitate adaptive behavior by enabling the orbitofrontal cortex to use environmental stimuli to gen
191 hippocampus, amygdala, ventral striatum, and orbitofrontal cortex volumes were related to lifetime ca
192 to MA use, smaller cortical thickness in the orbitofrontal cortex was associated with family history
193 tional connectivity between the amygdala and orbitofrontal cortex was compared between ASDs subgroups
194 Moreover, blunted activation of the medial orbitofrontal cortex was significantly correlated with a
195 ogical activity of individual neurons of the orbitofrontal cortex while rats performed a risk task th
196 diagnosis-by-age-by-distance interaction in orbitofrontal cortex with short-range FC being lower in
198 st (the caudate, the putamen, and the medial orbitofrontal cortex) were tested at a statistical thres
200 e, but the striatal network outperformed the orbitofrontal cortex, a finding replicated both in simul
201 the DMS CINs also depended completely on the orbitofrontal cortex, an area that has been proposed to
202 encoded in patterns of brain activity in the orbitofrontal cortex, an area that has been separately i
203 lower was their D2-type BPND in the lateral orbitofrontal cortex, an important region in value-based
204 ous, including the medial prefrontal cortex, orbitofrontal cortex, and different locations within the
205 attern separation between odor categories in orbitofrontal cortex, and impeded within-category genera
206 as the anterior/posterior cingulate cortex, orbitofrontal cortex, and medial temporal areas in diffe
208 ctivity among regions such as vmPFC, lateral orbitofrontal cortex, and parahippocampal gyrus (PHG) du
210 grey matter in the anterior insula, lateral orbitofrontal cortex, anterior cingulate and dorsal stri
211 empathy depends on coordinated functions of orbitofrontal cortex, anterior insula, anterior cingulat
212 hypometabolism in the medial occipital lobe, orbitofrontal cortex, anterior temporal lobe, and caudat
213 e ensemble in the nucleus accumbens, but not orbitofrontal cortex, compared with their surrounding ne
214 ted Fos neurons in central amygdala, but not orbitofrontal cortex, decreased "incubated" nicotine see
215 isted of voxels with unique projections from orbitofrontal cortex, dorsolateral prefrontal cortex, an
216 hibit convergent anatomical connections from orbitofrontal cortex, dorsolateral prefrontal cortex, an
217 ce has generally treated prefrontal regions (orbitofrontal cortex, dorsolateral prefrontal cortex, in
218 and emotional processing (thalamus, insula, orbitofrontal cortex, hippocampus, and anterior cingulat
219 cant reductions in gray matter volume in the orbitofrontal cortex, hippocampus, and cerebellum; white
220 vealed hypoactivation in additional hedonic (orbitofrontal cortex, insula, globus pallidus, putamen,
221 rey matter volume in the anterior cingulate, orbitofrontal cortex, left dorsolateral prefrontal corte
222 ial/ventral orbitofrontal, and ventrolateral orbitofrontal cortex, mediodorsal thalamus, or nucleus a
223 the ventromedial prefrontal cortex (vmPFC), orbitofrontal cortex, nucleus accumbens, hypothalamus, a
224 poral pole), and c) emotion-related regions (orbitofrontal cortex, temporal pole, and amygdala).
225 TSPO VT was measured in the dorsal caudate, orbitofrontal cortex, thalamus, ventral striatum, dorsal
226 r TSPO VT is elevated in the dorsal caudate, orbitofrontal cortex, thalamus, ventral striatum, dorsal
229 neurons in central and basolateral amygdala, orbitofrontal cortex, ventral and dorsal medial prefront
231 the same time, through its modulation of the orbitofrontal cortex, which processes salience attributi
233 dies, MAM (vs. SHAM) rats displayed abnormal orbitofrontal cortex-mediated decision-making processes,
262 significant asymmetry in both olfactory and orbitofrontal cortical odor-evoked activity, which is ex
263 superior frontal, middle frontal, and medial orbitofrontal cortical regions as well as a greater rate
264 hylphenidate was infused into prefrontal and orbitofrontal cortical regions as well as into several s
265 eft-sided ventral striatal-ventrolateral and orbitofrontal cortical reward-processing circuitry, resu
266 in the cerebellum, pons, left amygdala, and orbitofrontal cortices (cluster level, family-wise error
267 ision and taste, both the medial and lateral orbitofrontal cortices (OFC) maintained a valence code i
269 atients with bvFTD, with the addition of the orbitofrontal cortices and nucleus accumbens in patients
270 he development of dorsal frontal and lateral orbitofrontal cortices as well as the effects of family
271 seline MOR availability in the cingulate and orbitofrontal cortices was associated with the rate of s
272 , and emotion categories in the fusiform and orbitofrontal cortices were stereotypically biased and c
280 and middle frontal gyri, lateral and medial orbitofrontal gyri, right anterior insula, putamen, thal
281 the right hippocampus/parahippocampus, right orbitofrontal gyrus, right inferior temporal gyrus (ITG)
286 D patients correlated with hypometabolism in orbitofrontal (OFC) and posterior cingulate (PCC) cortic
288 entity and value are coded in piriform (PC), orbitofrontal (OFC) and ventromedial prefrontal (vmPFC)
290 ene silencing, we knocked down Gabra1 in the orbitofrontal prefrontal cortex (oPFC) in mice, decreasi
291 es on the principal pyramidal neurons of the orbitofrontal prefrontal cortex (oPFC) were also imaged
292 lapping hypofunction in ventral striatal and orbitofrontal regions in depression and schizophrenia du
293 as such as the thalamus, globus pallidus and orbitofrontal regions of the right hemisphere (with the
296 n over time in a region including insula and orbitofrontal, rostral, and dorsolateral prefrontal cort
297 cognitive modulation of pain, including the orbitofrontal, subgenual anterior cingulate, and anterio
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