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1 subjects (in insula, amygdala, putamen, and orbitofrontal cortex).
2 s; decreased brain activity in right lateral orbitofrontal cortex).
3 frontal cortex and decreased activity in the orbitofrontal cortex.
4 ces decoding of reward signals in the medial orbitofrontal cortex.
5 essary for the representation of outcomes in orbitofrontal cortex.
6 iously conceived as largely dependent on the orbitofrontal cortex.
7 er gray matter volumes in caudate and medial orbitofrontal cortex.
8 ight pulvinar thalamic nucleus and the right orbitofrontal cortex.
9 al temporal lobe, opercular cortex and right orbitofrontal cortex.
10 ked by visual cues between the VMPFC and the orbitofrontal cortex.
11 manipulations of dopamine and lesions of the orbitofrontal cortex.
12 in regions but not in the infant amygdala or orbitofrontal cortex.
13 d regions of the caudate, thalamus and right orbitofrontal cortex.
14 -dependent signal change in the amygdala and orbitofrontal cortex.
15 nnectivity and cortical thickness within the orbitofrontal cortex.
16 nd a small, circumscribed lesion in the left orbitofrontal cortex.
17 e amygdala, subgenual prefrontal cortex, and orbitofrontal cortex.
18 cingulate cortex (Brodmann area 32) and the orbitofrontal cortex.
19 al cortex, anterior cingulate cortex and the orbitofrontal cortex.
20 fic) satiation effects in both the vmPFC and orbitofrontal cortex.
21 cale for appetite and aversive values in the orbitofrontal cortex.
22 he amygdala/hippocampal complex, insula, and orbitofrontal cortex.
23 amygdala, the anterior hippocampus, and the orbitofrontal cortex.
24 mplitude coupling in LFP recordings from rat orbitofrontal cortex.
25 eductions were found in the bilateral medial orbitofrontal cortex.
26 ht amygdala, hippocampus, fusiform gyrus and orbitofrontal cortex.
27 l correlates in striatum, insula, and medial orbitofrontal cortex.
28 a in the mPFC and hippocampus but not in the orbitofrontal cortex.
29 , the striatum consistently outperformed the orbitofrontal cortex.
30 pairments can be linked to lateral or medial orbitofrontal cortex.
31 egration in the superior temporal sulcus and orbitofrontal cortex.
32 ng in addiction, here showing a role for the orbitofrontal cortex.
33 ations were seen in the ventral striatum and orbitofrontal cortex.
34 anges in hippocampus, insula, subgenual, and orbitofrontal cortex, a circuit implicated in the contro
35 e, but the striatal network outperformed the orbitofrontal cortex, a finding replicated both in simul
36 displayed decreased activation of the medial orbitofrontal cortex, a key region of reward processing.
37 We find that anticipatory signals in the orbitofrontal cortex about upcoming choice increase over
40 study provides evidence for the key role of orbitofrontal cortex activity in choice behavior and sho
41 associated with nucleus accumbens and medial orbitofrontal cortex activity, whereas distress was pref
43 he OFC, the agranular insula and the lateral orbitofrontal cortex (AI-OPNs and LO-OPNs, respectively)
44 ted hyperconnectivity in a network involving orbitofrontal cortex along with a less resilient global
45 correlated with externalizing behaviors, an orbitofrontal cortex-amygdala network predicted rates of
47 the DMS CINs also depended completely on the orbitofrontal cortex, an area that has been proposed to
48 encoded in patterns of brain activity in the orbitofrontal cortex, an area that has been separately i
49 lower was their D2-type BPND in the lateral orbitofrontal cortex, an important region in value-based
50 taste, olfactory, and flavor stimuli in the orbitofrontal cortex and a region to which it projects,
51 iors exhibited positive correlations between orbitofrontal cortex and amygdala structure, while these
53 correlated inversely with activations in the orbitofrontal cortex and brainstem during the stress con
56 y, we examined activity of single neurons in orbitofrontal cortex and in ventral and dorsal striatum
57 and RSFC between the midbrain and striatum, orbitofrontal cortex and insula in methamphetamine-depen
58 ation revealed that the two regions studied, orbitofrontal cortex and nucleus accumbens, are not sequ
59 and similar effects were found in the right orbitofrontal cortex and right inferior frontal gyrus.
60 and functional abnormalities in left lateral orbitofrontal cortex and right supplementary motor area,
62 g of distant connectivity alterations of the orbitofrontal cortex and the basal ganglia represents in
63 he anterior and middle cingulate cortex, the orbitofrontal cortex and the medial and ventromedial sup
66 ckwards toward the lost option, cells within orbitofrontal cortex and ventral striatum represented th
67 ous, including the medial prefrontal cortex, orbitofrontal cortex, and different locations within the
68 attern separation between odor categories in orbitofrontal cortex, and impeded within-category genera
70 as the anterior/posterior cingulate cortex, orbitofrontal cortex, and medial temporal areas in diffe
72 ctivity among regions such as vmPFC, lateral orbitofrontal cortex, and parahippocampal gyrus (PHG) du
74 ially the left hippocampus, the left lateral orbitofrontal cortex, and the bilateral isthmus cingulat
75 d nucleus accumbens, left-hemisphere insula, orbitofrontal cortex, and ventromedial prefrontal cortex
76 grey matter in the anterior insula, lateral orbitofrontal cortex, anterior cingulate and dorsal stri
77 empathy depends on coordinated functions of orbitofrontal cortex, anterior insula, anterior cingulat
78 hypometabolism in the medial occipital lobe, orbitofrontal cortex, anterior temporal lobe, and caudat
79 ronto-striatal circuit that differs from the orbitofrontal cortex-anterior cingulate cortex-caudate c
80 y excitotoxic lesions of either the anterior orbitofrontal cortex (antOFC) or ventrolateral prefronta
81 TEMENT The lateral and medial regions of the orbitofrontal cortex are cytoarchitectonically distinct
83 dentified the ventromedial prefrontal cortex/orbitofrontal cortex as the main structure in this circu
85 functional connectivity involved the medial orbitofrontal cortex Brodmann area 13, which is implicat
88 eased functional connectivity of the lateral orbitofrontal cortex Brodmann area 47/12 is related to d
89 t the functional connectivity of the lateral orbitofrontal cortex Brodmann area 47/12 with these thre
91 xpression and smaller hippocampal and medial orbitofrontal cortex, but not amygdala, volumes relative
92 late cortex and striatal-anterior prefrontal/orbitofrontal cortex circuits was significantly associat
94 e ensemble in the nucleus accumbens, but not orbitofrontal cortex, compared with their surrounding ne
95 es, as well as between the right amygdala to orbitofrontal cortex connectivity and levels of craving.
98 teral prefrontal cortex and amygdala-lateral orbitofrontal cortex coupling were shown in male BPD pat
99 ted Fos neurons in central amygdala, but not orbitofrontal cortex, decreased "incubated" nicotine see
100 these regions, but with the exception of the orbitofrontal cortex, densities normalized with a recove
102 isted of voxels with unique projections from orbitofrontal cortex, dorsolateral prefrontal cortex, an
103 hibit convergent anatomical connections from orbitofrontal cortex, dorsolateral prefrontal cortex, an
104 ce has generally treated prefrontal regions (orbitofrontal cortex, dorsolateral prefrontal cortex, in
105 ined the role of parvalbumin interneurons in orbitofrontal cortex during reversal learning by recordi
106 he degree of both affective processes in the orbitofrontal cortex during self-reflection and cognitiv
107 whole, showed hyperactivation in the medial orbitofrontal cortex during the acquisition of avoidance
109 ts of the ARs in the caudate nucleus and the orbitofrontal cortex for all of the subjects, and a non-
110 e performed with (123)I-PIP using postmortem orbitofrontal cortex from cognitively normal and AD huma
111 hometry analyses demonstrated greater medial orbitofrontal cortex gray matter intensity in controls t
113 and emotional processing (thalamus, insula, orbitofrontal cortex, hippocampus, and anterior cingulat
114 cant reductions in gray matter volume in the orbitofrontal cortex, hippocampus, and cerebellum; white
116 g of the functions of different parts of the orbitofrontal cortex in emotion helps to provide new ins
118 ess by recording single-unit activity in the orbitofrontal cortex in rats performing a choice task in
119 pecifically, BOLD was higher in the inferior orbitofrontal cortex in response to savory food cues.
120 rontal cortex, anterior cingulate cortex and orbitofrontal cortex in the frontal lobe from a total of
123 nt avoidance were seen immediately, those of orbitofrontal cortex inactivation were delayed and their
124 ns were observed in the putamen, insula, and orbitofrontal cortex (indicating relative preservation o
125 r show that this property of CINs depends on orbitofrontal cortex input and is correlated with choice
126 vealed hypoactivation in additional hedonic (orbitofrontal cortex, insula, globus pallidus, putamen,
128 and dorsal anterior cingulate cortex (ACC), orbitofrontal cortex, insula, nucleus accumbens, amygdal
129 task as well as from other sources, that the orbitofrontal cortex is a critical node in the neural ci
132 rey matter volume in the anterior cingulate, orbitofrontal cortex, left dorsolateral prefrontal corte
134 bstantial number of studies showing that the orbitofrontal cortex links events to reward values, wher
136 ionally distinct learning signals in lateral orbitofrontal cortex (lOFC) and the dopaminergic ventral
138 t work in macaques has suggested the lateral orbitofrontal cortex (lOFC) is relatively more concerned
139 sed if pharmacologic inactivation of lateral orbitofrontal cortex (lOFC) or DBS of the ventral striat
140 credit assignment, whereas damage to medial orbitofrontal cortex meant that patients were more likel
141 dies, MAM (vs. SHAM) rats displayed abnormal orbitofrontal cortex-mediated decision-making processes,
142 ial/ventral orbitofrontal, and ventrolateral orbitofrontal cortex, mediodorsal thalamus, or nucleus a
143 reward values are represented in the medial orbitofrontal cortex (mOFC) at the time of choice [7-9].
144 s or chemogenetic inactivation of the medial orbitofrontal cortex (mOFC) in rats induces failures in
145 Contrary to IL and AI, we found that medial orbitofrontal cortex (mOFC) projects densely through dor
146 overlapping valuation signals in the medial orbitofrontal cortex (mOFC) were observed for the three
147 a given reward, or "reinforcer." The medial orbitofrontal cortex (mOFC), a subregion of the ventrome
148 us accumbens, amygdala, anterior insula, and orbitofrontal cortex (n = 18 had analyzable fMRI data).
149 the ventromedial prefrontal cortex (vmPFC), orbitofrontal cortex, nucleus accumbens, hypothalamus, a
152 extracellular recordings in the striatum and orbitofrontal cortex of mice that learned the temporal r
153 d large-scale recordings in the striatum and orbitofrontal cortex of mice trained on a stimulus-rewar
155 processing of affect; nucleus accumbens and orbitofrontal cortex of the reward circuit; anterior ins
156 46, n = 2), the vLPFC (A46v, n = 2), and the orbitofrontal cortex (OF; n = 2) were placed for confirm
157 critical for odor memory and perception- and orbitofrontal cortex (OFC) - a region involved in revers
160 Recent studies have challenged the view that orbitofrontal cortex (OFC) and amygdala mediate flexible
161 pERK expression in medial prefrontal (mPFC), orbitofrontal cortex (OFC) and areas in striatum and amy
163 bregions of the frontal cortex including the orbitofrontal cortex (OFC) and dorsomedial prefrontal co
164 prefrontal cortex activation and suppressed orbitofrontal cortex (OFC) and hippocampus activation af
165 presentations of identity-specific reward in orbitofrontal cortex (OFC) and identity-general reward i
166 multaneously decrease neural activity in the orbitofrontal cortex (OFC) and increase activity in NAC
167 ned the activation patterns of cue-activated orbitofrontal cortex (OFC) and nucleus accumbens (NAc) s
168 omic and functional connectivity between the orbitofrontal cortex (OFC) and the amygdala in mice.
169 STATEMENT Dysfunctional interactions between orbitofrontal cortex (OFC) and the amygdala underlie sev
171 parallel, fMRI cross-adaptation in the right orbitofrontal cortex (OFC) and the left anterior tempora
173 ateral nucleus of the amygdala (BLA) and the orbitofrontal cortex (OFC) are involved in behavior that
174 h studied, the role of prominent inputs from orbitofrontal cortex (OFC) are less well understood.
175 enced value representations within the human orbitofrontal cortex (OFC) are thought to be organized t
178 including the basolateral amygdala (BLA) and orbitofrontal cortex (OFC) can accompany these same diso
179 lations of neurons and HGA recorded from the orbitofrontal cortex (OFC) encode similar information, a
180 ing economic decisions, offer value cells in orbitofrontal cortex (OFC) encode the values of offered
181 adigm, we identified reward-based changes in orbitofrontal cortex (OFC) for the whole odor and for a
182 urface expression assays using both mPFC and orbitofrontal cortex (OFC) from individual EC or IC rats
192 to either medial prefrontal cortex (mPFC) or orbitofrontal cortex (OFC) immediately prior to performa
194 tly recorded local field potentials from the OrbitoFrontal Cortex (OFC) in five human subjects perfor
195 utions of the basolateral amygdala (BLA) and orbitofrontal cortex (OFC) in rats to learning under exp
196 ored the role of basal IL-6 signaling in the orbitofrontal cortex (OFC) in reversal learning, a form
197 reased stress-induced activity in the medial orbitofrontal cortex (OFC) in the high CA group (p<0.01,
198 parate lines of research have implicated the orbitofrontal cortex (OFC) in the judgment of social tra
200 directed behavior.SIGNIFICANCE STATEMENT The orbitofrontal cortex (OFC) is critical for goal-directed
208 olume, higher functional connectivity in the orbitofrontal cortex (OFC) network, and higher structura
209 nd recorded from dorsomedial PFC (dmPFC) and orbitofrontal cortex (OFC) neurons while they were freel
210 the activity of neurons in the amygdala and orbitofrontal cortex (OFC) of monkeys during a Pavlovian
211 rk identified three groups of neurons in the orbitofrontal cortex (OFC) of monkeys engaged in economi
212 monkeys with bilateral lesions of either the orbitofrontal cortex (OFC) or the amygdala could learn a
215 al techniques in mice, we found that pairing orbitofrontal cortex (OFC) stimulation with sound stimul
216 reward contingencies, with the medial versus orbitofrontal cortex (OFC) subregions contributing diffe
218 orm of cognitive flexibility mediated by the orbitofrontal cortex (OFC) that we have used previously
219 from the anterior cingulate cortex (ACC) and orbitofrontal cortex (OFC) to assess network similaritie
220 graphic organization of projections from the orbitofrontal cortex (OFC) to the parahippocampal region
221 ed repetitive element loci (RE) in the human orbitofrontal cortex (OFC) using directional RNA sequenc
222 The caudate has dense connections with the orbitofrontal cortex (OFC) via the frontostriatal loops,
225 One hedonic hotspot was found in anterior orbitofrontal cortex (OFC), and another was found in pos
226 and ventral striatum, left insula and middle orbitofrontal cortex (OFC), and right insula projecting
228 er cortical gray matter than controls in the orbitofrontal cortex (OFC), anterior and posterior cingu
229 Other frontal regions, in particular the orbitofrontal cortex (OFC), are critical in directing be
230 entral medial prefrontal cortex (vmPFC), and orbitofrontal cortex (OFC), brain regions implicated in
231 restingly, we found that inactivation of the orbitofrontal cortex (OFC), but not the dorsal or ventra
234 vity in both medial and lateral parts of the orbitofrontal cortex (OFC), only the lateral OFC represe
235 vironmental context exposure is dependent on orbitofrontal cortex (OFC)-basolateral amygdala (BLA) in
236 LA-driven intra-amygdaloid paths and concise orbitofrontal cortex (OFC)-CeA-driven extra-amygdaloid c
252 ut by how that response (specifically in the orbitofrontal cortex; OFC) is mirrored at a later time w
253 ng value-guided learning, whereas the medial orbitofrontal cortex (often referred to as ventromedial
254 removal of serotonin or dopamine within the orbitofrontal cortex or dorsal striatum, respectively, i
255 ulated the food-related signal in the medial orbitofrontal cortex (P=0.01) and nucleus accumbens (P=0
257 once the stimulus is presented suggest that orbitofrontal cortex plays a role in transforming immedi
258 The primate amygdala projects to posterior orbitofrontal cortex (pOFC) directly and possibly indire
259 mygdala sends dense projections to posterior orbitofrontal cortex (pOFC) in pathways that are critica
260 nterior cingulate cortex (ACC) and posterior orbitofrontal cortex (pOFC) in rhesus monkeys to compare
261 irectional dialogue of the primate posterior orbitofrontal cortex (pOFC) with the amygdala is essenti
262 Here we show that basolateral amygdala to orbitofrontal cortex projections are required for expect
263 ts in the ventromedial prefrontal cortex and orbitofrontal cortex regardless of stimulus type and dis
264 bjects were presented, neuronal ensembles in orbitofrontal cortex represented distinct value-based sc
266 into occipital cortex (left hemisphere) and orbitofrontal cortex (right hemisphere); bilateral precu
269 response was higher in reward-related areas (orbitofrontal cortex, striatum) in a low-protein state t
270 es spread to frontal (lateral premotor area, orbitofrontal cortex, supplementary motor area, anteior
272 (P < .01) distant connectivity in the medial orbitofrontal cortex, temporal cortex, posterior cingula
273 poral pole), and c) emotion-related regions (orbitofrontal cortex, temporal pole, and amygdala).
274 TSPO VT was measured in the dorsal caudate, orbitofrontal cortex, thalamus, ventral striatum, dorsal
275 r TSPO VT is elevated in the dorsal caudate, orbitofrontal cortex, thalamus, ventral striatum, dorsal
276 n had greater activation in the left lateral orbitofrontal cortex than did low-risk children (t43 = -
277 lteration involving the ventral striatum and orbitofrontal cortex that predicted overall illness seve
278 al deficits and reduced synaptic efficacy in orbitofrontal cortex, the reversal of which by optogenet
282 gative connectivity between the amygdala and orbitofrontal cortex (thresholded at z > 1.70, P < .05).
283 facilitate adaptive behavior by enabling the orbitofrontal cortex to use environmental stimuli to gen
285 significantly correlated with TSPO VT in the orbitofrontal cortex (uncorrected Pearson correlation r
286 neurons in central and basolateral amygdala, orbitofrontal cortex, ventral and dorsal medial prefront
288 hippocampus, amygdala, ventral striatum, and orbitofrontal cortex volumes were related to lifetime ca
289 m, ventral pallidum, amygdala, midbrain, and orbitofrontal cortex (voxel threshold p < 0.005; cluster
290 to MA use, smaller cortical thickness in the orbitofrontal cortex was associated with family history
291 The craving-related signal in the medial orbitofrontal cortex was attenuated by inactivation of t
292 tional connectivity between the amygdala and orbitofrontal cortex was compared between ASDs subgroups
293 Moreover, blunted activation of the medial orbitofrontal cortex was significantly correlated with a
294 Remarkably, pyramidal neurons within the orbitofrontal cortex were also found to be smaller in si
295 st (the caudate, the putamen, and the medial orbitofrontal cortex) were tested at a statistical thres
297 increases in striatum, amygdala, and medial orbitofrontal cortex, whereas it decreased metabolism in
298 the same time, through its modulation of the orbitofrontal cortex, which processes salience attributi
299 ogical activity of individual neurons of the orbitofrontal cortex while rats performed a risk task th
300 diagnosis-by-age-by-distance interaction in orbitofrontal cortex with short-range FC being lower in
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