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1 Wound healing is complex and highly orchestrated.
2 ding how cellular pathways and processes are orchestrated.
3 rtant findings about how axon termination is orchestrated: (1) RPM-1 functions in parallel to RHO-1 a
5 pression, which functions to oppose TBET and orchestrate a continuum of effector-to-memory phenotypes
6 nals in a beta2 integrin-dependent manner to orchestrate a set of activation-mediated mechanisms that
7 ADP ribosylation factor (Arf) GTPases, which orchestrate a variety of regulatory functions in lipid a
8 chanism by which chronic TNF-alpha signaling orchestrates a functional interplay between mutant p53 a
11 s study, we demonstrate that neuronal TSC1/2 orchestrates a program of oligodendrocyte maturation thr
12 suppresses single-ended reactions, the IR/DR orchestrates a regulatory mechanism to enforce synapsis
13 gulation of PALB2 by ATR, ATR promotes HR by orchestrating a "CDK-to-ATR switch" post-resection, dire
14 any immune processes, but how miRNA circuits orchestrate aberrant intestinal inflammation during infl
16 can be of translational relevance to rapidly orchestrate adaptive immunity through DC maturation.
17 -autonomous and systemic DDR mechanisms that orchestrate adaptive responses that augment maintenance
19 t only transform our understanding of how T3 orchestrates adult brain lineage decisions, but also pro
23 ing ANT1 and mitochondrial dysfunction, SHP2 orchestrates an intrinsic regulatory loop to limit exces
24 tly highlighted a central role for IFN-Is in orchestrating an immunoregulatory network leading to the
25 ween embryonic and extraembryonic tissues to orchestrate and coordinate morphogenesis with changes in
26 numerous immune cell types but is ultimately orchestrated and sustained by the hematopoietic stem cel
27 d associated F-actin alignment, consequently orchestrating anisotropic traction stresses that drive c
29 tory and activating signals is essential for orchestrating appropriate inflammatory and immune respon
31 wever, how recruitment of a myriad of TRs is orchestrated at cis-regulatory modules (CRMs) to account
33 a series of highly regulated steps that are orchestrated at the molecular level by specific cyclins
36 te a critical role for the gut microbiota in orchestrating brain development and behavior, and the im
37 Pancreatic beta-cell insulin production is orchestrated by a complex circuitry involving intracellu
38 llular responses to type I IFN signaling are orchestrated by a complex network of regulatory pathways
41 at the propensity for omega-hydroxylation is orchestrated by active-site sterics, partially mediated
42 A model based on a putative feedforward loop orchestrated by Akt consistently predicted how the pathw
45 The intestinal immunity and tolerance are orchestrated by both the innate and the adaptive immune
46 gulation following spinal cord injury (SCI), orchestrated by CD200-ligand (CD200L) expressed by newly
48 essentially result from proteomic disorders orchestrated by changes in DNA and/or cytoplasmic mRNA.
50 f approximately 10 SD of head circumferences orchestrated by distinct mutations in the same gene.
52 tic make-up and environment, and thus may be orchestrated by epigenetic mechanisms like DNA methylati
54 ecruitment and retention in the epidermis is orchestrated by interactions with keratinocytes through
55 at metacognitive performance specifically is orchestrated by means of prefrontal theta oscillations.
56 During cell division, genome inheritance is orchestrated by microtubule attachments formed at kineto
60 rophil extracellular traps (NETs [NETosis]), orchestrated by peptidylarginine deiminase 4 (PAD4), dam
61 ex carbohydrates by the Bacteroides genus is orchestrated by polysaccharide utilization loci (PULs).
62 initiated by radiation-sensitive cells, but orchestrated by radiation-resistant components of joint
64 expression and function of TCR complexes are orchestrated by several fine-tuned cellular processes th
66 olution of inflammation is an active process orchestrated by specialized proresolving lipid mediators
67 ssed in lymphoid tissues was predicted to be orchestrated by specific immune genes that act as 'key p
70 pithelial cell (BECs) damages, thought to be orchestrated by T cells primed by antigen-presenting cel
71 Innate and adaptive lymphoid development is orchestrated by the activities of E proteins and their a
72 of metabolites and toxic organic solutes are orchestrated by the ATP-binding cassette (ABC) transport
73 the assembly of heterologous SNARE proteins orchestrated by the binding of Sec1/Munc18 (SM) proteins
75 ating environmental conditions are typically orchestrated by the circadian clock, an intrinsic time-k
76 Here, lysis of an infected bacterial cell is orchestrated by the expression and accumulation of a sta
78 proinflammatory state in the venous milieu, orchestrated by the HIF-induced NLRP3 inflammasome compl
80 rmation and function of synapses are tightly orchestrated by the precise timing of expression of spec
82 the cell and its turnover must be carefully orchestrated by ubiquitination and ubiquitin-proteasome
83 Two particularly important cellular programs orchestrated by Wnt signaling are proliferation and stem
85 hage (Mp) subsets (Ly6C(low) and Ly6C(high)) orchestrate cardiac recovery process following myocardia
88 Growth factors are signaling molecules which orchestrate cell growth, proliferation and differentiati
92 atory networks shape the landscape and hence orchestrate cellular decision-making in the presence of
94 inergic function by revealing the temporally orchestrated changes in prefrontal network synchrony mod
95 own about the molecular mechanism of how Shh orchestrates changes in the growth cone cytoskeleton tha
96 erone that associates with the replisome and orchestrates chromatin assembly following DNA synthesis.
97 cal epigenetic factor in Wnt signalling that orchestrates chromatin changes and transcription in huma
98 tumor suppression, non-coding transcription orchestrates chromatin folding and compartmentalization
100 ess called quorum sensing to communicate and orchestrate collective behaviours, including virulence f
102 e the function of endogenous immune cells to orchestrate complex mechanisms of repair; however, a dee
103 tatic interactions of disordered proteins to orchestrate complicated molecular gates such as the nucl
104 so involved in creating neuronal networks by orchestrating construction of the whole network during d
106 together, our findings demonstrate that G9a orchestrates critical epigenetic changes in cardiomyocyt
107 chiasmatic nucleus (SCN) of the hypothalamus orchestrates daily rhythms of physiology and behavior in
108 olved a multilayered immune system with well-orchestrated defense strategies against pathogen attack.
109 f Ag-specific humoral responses requires the orchestrated development and function of highly speciali
110 onse to stress and social stimuli depends on orchestrated development of hypothalamic neuronal circui
112 served protein that plays essential roles in orchestrating DNA replication timing, controlling nuclea
113 argest subunit of RNA polymerase II (Pol II) orchestrates dynamic recruitment of specific cellular ma
114 Together, our data showed that bta-miR-23a orchestrates early intramuscular adipogeneic commitment
115 hog (SHH) pathway is a key signaling pathway orchestrating embryonic development, mainly of the CNS a
116 To understand how these epigenomic writers orchestrate enhancer landscapes in cell differentiation,
117 s constitutes a sophisticated mechanism that orchestrates epithelial regeneration and maintenance of
119 neumonia, antibacterial defense requires the orchestrated expression of innate immunity mediators, in
121 nteractions in and out of cells must be well-orchestrated for the healthy functioning and regulation
123 f mammalian GATOR1 and GATOR2 to form a SZT2-orchestrated GATOR (SOG) complex with an essential role
126 n obligate brainstem-to-hypothalamus circuit orchestrating general stress excitation across multiple
128 ata provide evidence that the 5-LO/LTB4 axis orchestrates GVHD development and suggest it could be a
130 mic modifications at histone H3K27 and H3R26 orchestrate HIV-1 LTR-mediated transcription, and potent
132 uced inflammation plays an important role in orchestrating host defense by different cell types in no
136 ng Mycobacterium tuberculosis infection that orchestrates immune evasion strategies through the induc
139 eactions involving different metal catalysts orchestrated in concert constitute an attractive alterna
141 l diabetic retinopathy and that Muller cells orchestrate inflammatory responses in myeloid cells thro
142 fying enzymes and ubiquitination events that orchestrate inflammatory responses, with an emphasis on
143 lay between periostin and renal inflammation orchestrates inflammatory and fibrotic responses, drivin
145 rm multimodal memories in the hippocampus by orchestrating input from multiple cortical sources.
146 A critical role of circadian oscillators in orchestrating insulin secretion and islet gene transcrip
147 o paralogous proteins (GlnB and GlnK), which orchestrate interactions with regulators of gene express
150 An immune response consists of a finely orchestrated interplay between initial recognition of po
152 -gammaR signaling exerts additive effects in orchestrating intracerebral inflammation, leading to the
153 RE11 nuclease subunit of the MRN complex and orchestrates its nucleolytic activity to the ATR kinase
155 Here, we review how these factors jointly orchestrate light adaptation over a large dynamic range.
157 re in mice triggers a metabolic program that orchestrates lipoprotein processing in brown adipose tis
158 ttle is understood about the mechanisms that orchestrate LMP1 incorporation into these vesicles.
159 with hematopoietic cells and the microbiota orchestrate local immune homeostasis and inflammation.
163 linding inflammatory reaction in the cornea, orchestrated mainly by proinflammatory CD4 T cells and c
164 I and highlights how individual gut bacteria orchestrate manifold enzymes to metabolize the most chal
167 review here these essential roles of DCs in orchestrating mechanisms of peripheral T cell tolerance
168 se tissue macrophages (ATMs) are key players orchestrating metabolic inflammation, and ER stress enha
170 at activated AMPK and Atg14p are required to orchestrate micro-lipophagy for energy production in sta
171 totic cells from epithelial tissues requires orchestrated morphological rearrangements of the apoptot
173 se PfCRK4 is a key cell-cycle regulator that orchestrates multiple rounds of DNA replication througho
174 Here we report that fully reduced HMGB1 orchestrates muscle and liver regeneration via CXCR4, wh
176 igurations and regulatory relationships that orchestrate neuronal delamination and may inform mechani
177 known about how these regulators interact to orchestrate nitrogen (N) responses and cell-cycle regula
178 ed in the regulation of microtubule dynamics orchestrates NLRP3 inflammasome activation by controllin
181 Moreover, deletion of DJ-1, which helps orchestrate nuclear oxidant defenses and Sirt3 in mice l
182 e large-scale cell identity shifts are often orchestrated on an epigenetic level, we screened for can
183 lterations in transcriptional regulators can orchestrate oncogenic gene expression programs in cancer
184 echanisms that disseminate the proteins that orchestrate organ and tissue development have been a maj
186 egulator of DSB-repair, the absence of which orchestrates persistent DSB signaling to senescence, tis
187 ase 65 (GAD65) cells, but their interplay in orchestrating physical activity is not fully understood.
189 uction after early life allergen exposure by orchestrating PNEC innervation and secretion of GABA.
192 ls in the adaptive immune system is a highly orchestrated process dictated by multiples cues from the
193 ermutations are amalgamated into circuits to orchestrate processes of interest to the hematologist an
194 scoveries are revealing that these same ATGs orchestrate processes that are related to, and yet clear
195 MZT) is one of the most profound and tightly orchestrated processes during the early life of embryos,
196 diac injury response, but its direct role in orchestrating programmed fibroblast differentiation and
197 that polarized T helper lymphocyte responses orchestrate progression of intrahepatic biliary injury i
199 cell-type-specific roles of epithelial AR in orchestrating prostate homeostasis, and question the not
201 suggest that C5a could be an initial signal orchestrating pulp nerve sprouting beneath carious injur
204 wealth of pro- and antioxidant systems that orchestrate region-specific ROS production and removal.
210 x morphological transformation of Gag via an orchestrated series of proteolytic cleavage events.
213 ructural and photochemical basis of how they orchestrate signal transduction and control gene express
214 a variety of spatiotemporal patterns, which orchestrate signaling activity in different subcellular
216 cognition mechanism of PTPN12 by CDK2, which orchestrated signaling crosstalk between the oncogenic C
217 itive natural products, we conduct carefully orchestrated site- and diastereoselective oxidations and
220 ties in the cortex, but how they interact to orchestrate specific band activity remains largely unkno
222 develops gradually through a series of five orchestrated stages, making it likely that V1 participat
223 y regulate a large number of common genes to orchestrate stem versus differentiated trophoblast fate.
228 s understanding of how the TRF2(TRFH) domain orchestrates telomere end protection and reveals how the
231 e show here that PUL1,6-beta-glucan does not orchestrate the degradation of a plant polysaccharide bu
232 ications of our findings for mechanisms that orchestrate the differentiation of monospecific lymphocy
236 hat RARgamma is released from the nucleus to orchestrate the formation of the cytosolic death complex
237 xns) and neuroligins (Nlgns) bidirectionally orchestrate the function of presynaptic and postsynaptic
238 rofessional phagocytes of the brain and help orchestrate the immunological response by interacting wi
240 esign of self-assembling building blocks can orchestrate the organization of surrounding solvent mole
241 gradients of extracellular metabolites that orchestrate the phenotypic diversity of cells in the tum
242 eye, Eyes absent (Eya) and Sine oculis (So) orchestrate the progression of progenitor cells from asy
243 d that this population signal can be used to orchestrate the rhythmic structure of the internally tim
244 opment is driven by regulatory programs that orchestrate the transcription of protein-coding and nonc
250 rentiation of anterior progenitors, and also orchestrates the development of the infundibulum and Rat
251 indings reveal that Nf2 is a key player that orchestrates the differential growth of optic neuroepith
252 repressor Growth factor independent 1 (Gfi1) orchestrates the fidelity of the DP gene expression prog
255 e conclude that ciliary Hh signaling by FAPs orchestrates the regenerative response to skeletal muscl
256 ors of a molecular and cellular pathway that orchestrates the resolution of chronic inflammation.
258 constitutes the transcriptional profile that orchestrates the structural and functional characteristi
259 the activation of Gi-coupled GPCRs at the LE orchestrates the TE retraction in RAW264.7 macrophages.
262 h of these subunits plays a distinct role in orchestrating the assembly of the pre-replication comple
263 apoptotic and functional exhaustion, thereby orchestrating the balance between immunity and tolerance
264 ontrolled trans activity on one promoter and orchestrating the coordinated starch and fructan synthes
265 l needs require the development of pipelines orchestrating the entire workflow and optimizing usage o
266 ists and antagonists have essential roles in orchestrating the formation of a balanced rostral-caudal
267 suppressor protein plays a critical role in orchestrating the genomic response to various stress sig
268 ly response genes (IEGs) are responsible for orchestrating the initial neutrophil response to mycobac
269 icating a prominent role of these neurons in orchestrating the neuroendocrine, autonomic and behavior
271 atory protein can maintain specificity while orchestrating the response of many downstream genes.
272 stone ubiquitylation plays a central role in orchestrating the response to DNA double-strand breaks (
273 anistic behaviors, and the design principles orchestrating the signal transduction roles of the Hha p
274 he importance of protein tyrosine kinases in orchestrating the tyrosine phosphorylation networks and
276 cate that FOXP1 attenuates MSC senescence by orchestrating their cell-fate switch while maintaining t
277 thogenic bacteria are extremely efficient in orchestrating their response to these signals through co
280 active, excessively synchronized iSPNs could orchestrate these pathological rhythms in basal ganglia
283 players involved, and how they cooperate to orchestrate this critical aspect of platelet biology.
285 is discussed in terms of the driving forces orchestrating this highly efficient multilevel recogniti
288 es, the basal transcription in interphase is orchestrated through the regulation by kinases (Kin28, B
290 llaboration between two distinct Rab-protein-orchestrated trafficking circuits in bladder epithelial
293 cycle, the maturing viral particles undergo orchestrated translocation to specialized regions within
294 kinases in cHL exhibit pleiotropic effects, orchestrating tumor immune escape and supporting RS cell
299 ivotal significance of VBW myofibroblasts in orchestrating ventral midline closure by mediating the r
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