ライフサイエンスコーパス: organ donor

1 thyroid hormone in the brain-dead potential organ donor.

2 tigations, LCMV could not be detected in the organ donor.

3 between the transplant surgeon and the live-organ donor.

4 source of the West Nile virus viremia in the organ donor.

5 and age-dependent probability of becoming an organ donor.

6 willingness of individuals to be a deceased organ donor.

7 C patients, compared to control samples from organ donors.

8 psychosocial evaluation for eligible living organ donors.

9 mucosal tissues obtained from 56 individual organ donors.

10 rs per 100 eligible deaths were converted to organ donors.

11 A total of 119 patients became actual organ donors.

12 nt screening practices of potential deceased organ donors.

13 explained etiology, especially for potential organ donors.

14 work database from 2000 to 2012 of all solid organ donors.

15 tive than NAT for the screening of potential organ donors.

16 in kidney allograft recipients and deceased organ donors.

17 , particularly when patients were registered organ donors.

18 n of thyroid hormone to brain-dead potential organ donors.

19 from DCD and donors after brain death (DBD) organ donors.

20 ations for screening and management of TB in organ donors.

21 ght patients with CHI and from adult cadaver organ donors.

22 ancreas was not recovered in 48% (11,820) of organ donors.

23 1 may serve to increase the pool of eligible organ donors.

24 btained from the knee and ankle joints of 34 organ donors.

25 ation today is how to increase the number of organ donors.

26 a series of 10,000 consecutive UK cadaveric organ donors.

27 d, the main difficulty being the shortage of organ donors.

28 Two mothers also became organ donors.

29 ganizations to identify brain-dead potential organ donors.

30 hand) was performed in 9 human heart-beating organ donors.

31 ust be developed to exclude CMV from porcine organ donors.

32 ogressively outstripping the availability of organ donors.

33 ths of patients who became non-heart-beating organ donors.

34 e of tone in human LES samples obtained from organ donors.

35 he 100 experimental animals could be used as organ donors.

36 different anatomic compartments in six human organ donors.

37 Upper limbs were procured from brain-dead organ donors.

38 acini isolated from cadaveric pancreata from organ donors.

39 n regarding the number of potential deceased organ donors.

40 disc cells isolated from healthy, pain-free organ donors.

41 ry (registrants) and their value in terms of organ donors.

42 e compared with those from three nondiabetic organ donors.

43 the DonateLife Audit of whom 553 (8.1%) were organ donors.

44 nt psychosocial screening programs of living organ donors.

45 there continues to be a critical shortage of organ donors.

46 quency of false-positive results in deceased organ donors.

47 possible to estimate the expected number of organ donors.

48 ific for the identification of survivors and organ donors.

49 tines) sites from a population of brain-dead organ donors (2 months-93 years; n = 291) across eight c

50 f T. cruzi antibodies in Southern California organ donors, 404 samples from deceased organ donors bet

51 potential donors proceeding to become actual organ donors (64% vs 75%, P = 0.007).

52 Those registered as organ donor (69.8%) had better knowledge, perceptions, a

53 nial hemorrhage than were all other deceased organ donors (85% vs. 57%, p < 0.001).

54 plant recipients developed encephalitis from organ donor-acquired lymphocytic choriomeningitis virus.

55 Given the stable number of potential organ donors after brain death, donors after circulatory

56 Twelve patients who were pediatric organ donors after cardiac death.

57 ecessarily translate to individuals becoming organ donors after death.

58 pothermia, as compared with normothermia, in organ donors after declaration of death according to neu

59 We enrolled organ donors (after declaration of death according to ne

60 improve the identification and reporting of organ donors aiming at an annual rate of 15 donors per m

61 ransplantation, making the care of potential organ donors an important issue.

62 Organ donor and all transplant recipient medical records

63 Persons who donated blood to the organ donor and associated blood components were identif

64 identified West Nile virus infection in the organ donor and in all four organ recipients.

65 ebrospinal fluid, and urine samples from the organ donor and recipients were tested for WNV infection

66 es have the potential to instrumentalize the organ donor and that they should be restricted to cases

67 The serological status of the organ donor and the duration of CMV prophylaxis are pred

68 We reviewed the medical records of the organ donor and the recipients.

69 To minimize variables associated with the organ donor and with tissue processing, all of the graft

70 We recruited 30 consecutive brain-dead organ donors and 78 recipients between April 11, 2004, a

71 ed from pancreata procured from 12 cadaveric organ donors and cultured in the M-SFM for up to 2 month

72 nce of anti-HTLV I/II antibodies among solid organ donors and determine the number of false positive

73 atory response characteristics in brain-dead organ donors and examine associations with organ transpl

74 obtained from nonfailing hearts of unmatched organ donors and failing hearts at the time of transplan

75 tic digestion from normal ankle cartilage of organ donors and from osteoarthritic (OA) knee tissue ob

76 eload responsiveness is common in brain-dead organ donors and is associated with higher inflammatory

77 The second cohort consisted of prior organ donors and matched nondonors who underwent decease

78 The first cohort consisted of prior organ donors and matched nondonors who were wait-listed

79 ntation offers a solution to the shortage of organ donors and may offer resistance to human-specific

80 We characterized CD8 T cells derived from organ donors and patients with end-stage HCV infection t

81 HHV-8 status can be useful when considering organ donors and recipients with risk factors, although

82 However, the extreme shortage of matched organ donors and the necessity for chronic immunosuppres

83 try needs to increase the number of deceased organ donors and the potential impact of a change to opt

84 legislation and its benefits for registered organ donors and their families.

85 cs and risk factors for ZIKV infection among organ donors and transplant outcomes among recipients of

86 sues were selected from groups of nonfailing organ donors and transplant recipients with endstage isc

87 in human islets obtained from deceased adult organ donors and transplanted them into hyperglycemic, i

88 NV infections among recipients from the same organ donor, and remove any potentially infected blood p

89 ent acquisition of HIV by prospective living organ donors, and to conduct HIV antibody testing and NA

90 were also those who would be unlikely to be organ donors anyway, because they tended to hold negativ

91 for such studies and the fact that deceased organ donors are not covered by extant federal regulatio

92 Organ donors are often implicated as the source of postt

93 Deceased organ donors are routinely screened for behaviors that i

94 policy requires that all potential deceased organ donors are screened for human immunodeficiency (HI

95 Organ donors are sources of physiologically healthy orga

96 Organ donors are tested for anti-HTLV antibodies and don

97 tion is not uncommon as approximately 23% of organ donors are uninsured.

98 As more expanded-criteria organ donors are used to bridge the widening gap between

99 ed its platform to allow members to specify "Organ Donor" as part of their profile.

100 n-dead patients who became non-heart-beating organ donors at the University of Pittsburgh Medical Cen

101 t describes the use of this technology in an organ donor awaiting harvesting.

102 tions related to management of the potential organ donor, based on the available literature and exper

103 Serum specimens obtained from the organ donor before and immediately after blood transfusi

104 from the costal diaphragms of 14 brain-dead organ donors before organ harvest (case subjects) and co

105 The effect that targeted mild hypothermia in organ donors before organ recovery has on the rate of de

106 Part I: All solid organ donors between 1/95-8/97 who would have met criter

107 There were 10 facial VCA procurements in organ donors between December 2008 and October 2014.

108 rnia organ donors, 404 samples from deceased organ donors between May 2002 to April 2004 were screene

109 Conditioning the brain-dead organ donor by altering metabolism could be a novel appr

110 Current screening of deceased organ donors by RPR yields a significant number of false

111 Hormonal therapy to the brain-dead potential organ donor can include thyroid hormone (triiodothyronin

112 In all, tested organs donor cells undergo "licensing" for pathogenicity

113 from patients undergoing transplantation or organ donors (CF samples=18; non-CF, nonbronchiectatic s

114 Household income was a predictor of organ donor consent only in whites.

115 ernment in the past, its implications on the organ donor consent process, and its potential impact on

116 r(s) associated with both race and obtaining organ donor consent.

117 be applied at any institution with access to organ donors consenting to tissue donation for research,

118 nsplants, the suitability of pancreases from organ donors considered inappropriate for pancreas trans

119 The ethical debate of advertising for organ donors continues.

120 man AAA tissue samples compared with that in organ donor controls.

121 e status of both the organ recipient and the organ donor critically influences allograft outcome.

122 periences of brief cardiopulmonary arrest in organ donors did not affect post-OLT hepatic allograft s

123 liver, and an arterial segment from a common organ donor died of encephalitis of an unknown cause.

124 and lymphoid tissues of T1D and nondiabetic organ donors differ in the amount and distribution of HA

125 mposition of the national pool of brain-dead organ donors during a three-year period and, on the basi

126 ified a total of 18,524 brain-dead potential organ donors during the study period.

127 Expanded criteria deceased organ donors (ECD) are a source of kidneys that permit m

128 To overcome the scarcity of organ donors, elderly RT candidates should be encouraged

129 In conclusion, these data suggest that prior organ donors experience brief waiting time for kidney tr

130 lear cause of death in a potential pediatric organ donor, factors such as parental consanguinity shou

131 mission of melanoma by apparent disease-free organ donors following removal of a primary melanoma up

132 seeking organ transplantation and serving as organ donors for HIV-positive recipients, HHV-8 prevalen

133 Miniature swine are likely to be suitable organ donors for humans.

134 The shortage of organ donors for kidney transplants has made the expansi

135 S. policy requires screening of all deceased organ donors for syphilis infection.

136 The severe shortage of organ donors for treating patients with liver disease ha

137 We identified all UK deceased organ donors from 2003 to 2015 with a disclosed history

138 All organ donors from a single organ procurement organizatio

139 The organ donor had been healthy before having a subarachnoi

140 The organ donor had received blood transfusions from 63 dono

141 Twenty-one deceased organ donors had a predonation diagnosis of ITP.

142 At trial termination, 370 organ donors had been enrolled (180 in the hypothermia g

143 tion (CPR) of a person destined to become an organ donor has been associated with overall poor donor

144 uccess in increasing the number of cadaveric organ donors has created a supply-demand crisis.

145 The shortage of organ donors has impeded the development of human hepato

146 The number of deceased organ donors has increased from 709 (12.0 per million po

147 The current shortage of organ donors has led many centers to use marginal and no

148 The decline in heart-beating brainstem dead organ donors has necessitated the search for other organ

149 the bone marrow (BM) of heparinized deceased organ donors (HDODs).

150 Antibodies that are specific to organ donor HLA have been involved in the majority of ca

151 o represent an underused source of potential organ donors; however, there is a paucity of data regard

152 ct to ICOD were finally medically unsuitable organ donors.ICOD contributed to 24% of the 491 actual d

153 imary outcome measure was potential deceased organ donors (identified by the presence of diagnostic c

154 , we tested 1,408 specimens from prospective organ donors in 2002 and 2003.

155 to estimate the number of potential deceased organ donors in Canada.

156 kistan, Egypt, and the Philippines, deceased organ donors in Colombia, and executed prisoners in Chin

157 <18 years) can ethically serve as live solid organ donors in exceptional circumstances.

158 ucosal tissue T cells derived from pediatric organ donors in the first two years of life, as compared

159 Improving the management of potential organ donors in the intensive care unit could meet an im

160 .8 per million of population [pmp]) deceased organ donors in the United Kingdom from 1999 to 2009.

161 % of the increase in the numbers of deceased organ donors in the United Kingdom.

162 2013 modification, over 20% of all deceased organ donors in the United States were identified as PHS

163 uidelines and no data on the incidence among organ donors in the US.

164 g (RNA-seq) on islets from multiple deceased organ donors, including children, healthy adults, and in

165 On the first day of the Facebook organ donor initiative, there were 13 054 new online reg

166 lantation of undetected (occult) cancer from organ donor into immunosuppressed recipients.

167 nt or undiagnosed active TB in the potential organ donor is critical to prevent emergence of disease

168 efits and costs that accrue when a cadaveric organ donor is procured.

169 dicted annual number of brain-dead potential organ donors is between 10,500 and 13,800.

170 virus type 1 (HTLV-1) screening of blood and organ donors is not mandatory in Germany because of its

171 performed, and the number of false positive organ donors is unknown.

172 nor's participation in the study, ended when organ donors left the intensive care unit for organ reco

173 Our results reveal that organ donors maintain tissue homeostasis, and are a valu

174 We studied a cohort of 1872 potential organ donors managed by the California Transplant Donor

175 after brain stem herniation in 980 potential organ donors managed by the California Transplant Donor

176 A total of 1043 organ donors managed from 2001-2006 were initially studi

177 orating expertise in critical care medicine, organ donor management, and transplantation.

178 Many of the common ECG abnormalities seen in organ donors may result from the heightened state of sym

179 increasing the willingness to be a deceased organ donor (measured as commitment to donate and/or int

180 All surgeons operating on a living organ donor must select vascular control techniques that

181 l profit." Christian authorities insist that organ donors must not accrue economic advantage, and "se

182 iac artery vessels were harvested from liver organ donors (n=8).

183 The New York Organ Donor Network (NYODN) established an Infectious Di

184 , matched normal adjacent to tumor (AT), and organ donor (OD).

185 little experience with caring for potential organ donors (odds ratio, 1.49; 95% CI, 1.09-2.04).

186 0.32-0.53; p < 0.001), more often potential organ donors (odds ratio, 1.92; 95% CI, 1.56-2.35; p < 0

187 Solid organ donors often develop hypotension due to vasodilati

188 Among brain-dead organ donors, older age donors contribute fewer organs f

189 Last year, from the approximately 6,000 organ donors, only approximately 1,500 pancreata were us

190 er gram of human liver (n = 6) obtained from organ donors or directly from surgery is, on average, le

191 acute rejection response, we used Tg mice as organ donors or recipients of MHC-incompatible heart gra

192 about the expected ECG findings in potential organ donors or the clinical significance of any identif

193 ning hundreds of thousands of cells in human organ donor pancreata, we show that quantitative graph c

194 More information is needed about cadaver organ donor pathophysiology.

195 L1TCs have a significant number of potential organ donors (PODs).

196 rs has been used at our center to expand the organ donor pool and decrease the waiting time for decea

197 novel therapeutic approaches to maximize the organ donor pool through the safer use of liver transpla

198 novel therapeutic approaches to maximize the organ donor pool through the safer use of liver transpla

199 r to prevent liver IRI and thus maximize the organ donor pool used for transplantation.

200 t of recommendations aimed at maximizing the organ donor pool while safeguarding the interests of pot

201 f IRI, to improve liver function, expand the organ donor pool, and improve the overall success of liv

202 tion: shorter waiting time, expansion of the organ donor pool, and improved short-term and long-term

203 romising potential to increase the cadaveric organ donor pool, especially for kidneys.

204 to improve organ function and to expand the organ donor pool, problems still exist with the current

205 on or strategies to increase the size of the organ donor pool, such as xenotransplantation, are neede

206 ll outcomes and could potentially expand the organ donor pool.

207 DT) may play an important role in increasing organ donor pool.

208 ther staff in intensive care units with high organ donor potential.

209 The limited availability of deceased organ donors, prolongation of waiting time, and increasi

210 tissues adjacent to tumor, and 4 age-matched organ-donor prostate tissues.

211 ostate tissues, matched blood specimens, and organ donor prostates.

212 ent to tumor, in comparison with age-matched organ-donor prostates.

213 eas transplant but because of differences in organ donor, recipient, and transplant characteristics.

214 ering the absence of systematic screening of organ donors/recipients for HHV-8 infection, HHV-8-relat

215 This retrospective review of organ donor records was designed to evaluate the practic

216 Previous discussion and Organ Donor Register (ODR) enrollment both correlate wit

217 ue Act (2004) should be removed, and (7) the Organ Donor Register should be expanded to include poten

218 Within the student organization, organ donor registration increased by 28%.

219 , motivated 19 623 people to go to a state's organ donor registration page, and had 9000 documented o

220 vehicle (MV) clerks are at the epicenter of organ donor registration.

221 cognitive and attitudinal dimensions impact organ donor registration.

222 r registration page, and had 9000 documented organ donor registrations.

223 considerable investment in the promotion of organ donor registries.

224 d seven hundred eight individuals joined the organ donor registry (95% confidence interval [95% CI],

225 -based educational interventions to increase organ donor registry participation and family notificati

226 The number of deceased organ donors remains stable but donor age is increasing.

227 In 2000, the Consensus Statement on the Live Organ Donor reported that "direct financial compensation

228 luded if they were declared brain dead, were organ donors, required high-frequency ventilation, or if

229 The present scarcity of organ donors requires consideration of grafts from sourc

230 irst two years of life, as compared to adult organ donors, revealing early compartmentalization of T

231 and mucosal tissues obtained from individual organ donors, revealing tissue-intrinsic compartmentaliz

232 ers are an inconsistent metric for assessing organ donor risk, irrespective of HIV status.

233 WNV RNA was retrospectively detected in the organ donor's serum.

234 d1 in total liver RNA extracted from cadaver organ donor samples from reduced human grafts and explan

235 ent pulmonary autograft surgery and 8 normal organ donors, samples from the PA and aorta were analyze

236 hirty-two of 3,555 (0.9%) potential deceased organ donors screened during the study period showed a p

237 es the use of nucleic acid testing (NAT) for organ donor screening.

238 Nondiabetic organ donors served as controls.

239 Nevertheless, with the continuing organ donor shortage for cardiac transplantation, left v

240 In some regions, the organ donor shortage has resulted in a substantial incre

241 BACKGROUND.: Due to ongoing organ donor shortage, an increasing number of adult live

242 ure (FHF), but its use is limited because of organ donor shortage, associated high costs, and the req

243 c death (DCD) donors are used in view of the organ donor shortage.

244 Despite a national organ-donor shortage and a growing population of patient

245 Notwithstanding the widely acknowledged organ-donor shortage coupled with the expanded waiting l

246 Organ donor shortages continue to persist, especially in

247 Potential organ donors should be assessed for unexplained fever an

248 Potential organ donors should be carefully screened for a history

249 Options for greater public recognition for organ donors should be explored.

250 testing (NAT) for the screening of potential organ donors should be reserved to high-risk donors.

251 nt-based risk factors for PNF independent of organ donor source.

252 on were offered to those considering the new organ donor status.

253 dance is made the dominant principle guiding organ donor testing, an unintended consequence may be an

254 ulted in an increased frequency of potential organ donors that carry the virus.

255 f a severe shortage of kidneys from deceased organ donors that limits access to transplantation for m

256 S) changed the criteria intended to identify organ donors that put the associated organ recipients at

257 the liver function tests are elevated in an organ donor, the hepatic allograft is suitable for OLT i

258 Compared with the standard risk deceased organ donor, the PHS donor was younger, male, died from

259 012, 96,028 (3.3%) were a "possible deceased-organ donor." The two proposed metrics of OPO performanc

260 Using our organ donor tissue resource, we analyzed cDC subset dist

261 ing the transmission of rabies virus from an organ donor to multiple recipients underscores the chall

262 lower esophageal sphincter (N-LES) of human organ donors to examine the physiologic signal transduct

263 rt the concept of extending the criteria for organ donors to include modest coronary atherosclerosis.

264 d, iliac artery grafts procured from cadaver organ donors to reconstruct transplant renal arteries in

265 ding death and appropriately refer potential organ donors to the local organ procurement organization

266 even intermittent hypoxia (e.g., in deceased organ donors) to protect from liver IRI.

267 rospective longitudinal observation study of organ donors treated at a major metropolitan level I tra

268 LV-1 transmission event caused by a multiple organ donor was investigated.

269 The recipient of a kidney from the same organ donor was not affected.

270 on the previous transplant procedure and the organ donor was obtained from the Eurotransplant Foundat

271 Serum from the organ donor was positive for WNV IgM but negative for WN

272 ts' knowledge about how to register to be an organ donor was the dominant dimension for donor registr

273 The value of registrants in terms of organ donors was computed based on a registrant's age-de

274 ctional hemodynamic monitoring in brain-dead organ donors, we test the hypothesis that donor preload

275 Two additional recipients from the same organ donor were identified, their clinical and exposure

276 Fifty organ donors were evaluated for hemodynamic instability,

277 from pubertal and adult age group cadaveric organ donors were harvested and profiled using 20,000 el

278 Positive ZIKV tests in local deceased organ donors were investigated from 6/2016 to 1/2017.

279 e focused on increasing the number of living organ donors, which in 2001 for the first time exceeded

280 t influence individuals' decisions to become organ donors, which may be effectively targeted by inter

281 the residual pancreatic islets of a deceased organ donor who had T1D.

282 islets from six DiViD study patients and two organ donors who died at the onset of T1D, and the findi

283 s from the residual pancreatic islets of two organ donors who had T1D also recognize HIPs.

284 priority in kidney allocation to prior live organ donors who require a kidney transplant.

285 nd biceps specimens obtained from brain-dead organ donors who underwent MV (15-176 h) and age-matched

286 8-month-old rats and in human islets from 53 organ donors with ages ranging from 17 to 74 years.

287 ude patients from the Network for Pancreatic Organ Donors with Diabetes (U.S.) and Diabetes Virus Det

288 sed by adapting existing approaches used for organ donors with hepatitis.

289 with horizontal strabismus and from deceased organ donors with normal EOMs.

290 g T cells from inflamed pancreatic islets of organ donors with recent-onset T1D.

291 Studies of organ donors with T1D that have examined T cells in panc

292 the reconciliation of an increased need for organ donors with the concern for donor safety.

293 gical examination of pancreata from diabetic organ donors with the goal of providing a foundation for

294 alpha-cell mass in pancreata recovered from organ donors with type 1 diabetes (n = 80), as well as f

295 om inflamed pancreatic islets of three young organ donors with type 1 diabetes with a short disease d

296 Examination of pancreata from age-matched organ donors with type 2 diabetes mellitus (DM) treated

297 y six times higher than the number of actual organ donors, with the greatest loss of potential due to

298 vasopressin deficiency in hypotensive solid organ donors without clinical evidence of diabetes insip

299 ion (DiViD) study, compared with islets from organ donors without diabetes.

300 lapse undergoing mitral valve repair or from organ donors without mitral valve disease.