ライフサイエンスコーパス: organic anion transporter

1 c2), the principal canalicular multispecific organic anion transporter.

2 acids is an important function of the renal organic anion transporter.

3 inated by its interaction with the classical organic anion transporter.

4 s was effectively limited to the "classical" organic anion transporter.

5 Human organic anion transporter 1 (hOAT1) belongs to a superfa

6 Human organic anion transporter 1 (hOAT1) plays a critical rol

7 MDCK cells transfected stably with the human organic anion transporter 1 (hOAT1), the hypothesis that

8 cell line stably transfected with the human organic anion transporter 1 (hOAT1).

9 m a human renal library and designated human organic anion transporter 1 (hOAT1).

10 to other anionic substrates, the human renal organic anion transporter 1 (hOATI) is capable of transp

11 Organic anion transporter 1 (OAT1) mediates the body dis

12 Organic anion transporter 1 (OAT1), originally identifie

13 nces the kinetic interaction of ligands with organic anion transporter 1 (OAT1).

14 entially affected by the in vivo deletion of organic anion transporter 1 (Oat1, Slc22a6, originally N

15 Importantly, both hOAT1 and rat renal organic anion transporter 1 (rROAT1) mediated saturable,

16 ids are substrates for the renal basolateral organic anion transporter-1 (Oat1) from rat kidney.

17 Notably, organic anion transporter-1 (OAT1) knockout mice express

18 Organic anion transporter-1 (OAT1) mediates the body dis

19 Organic anion transporter-1 (OAT1) mediates the body's d

20 nd non-steroidal anti-inflammatory drugs) is organic anion transporter-1 (OAT1), originally identifie

21 MDCK cells that were transfected with human organic anion transporter-1 were used.

22 droxylase (Cyp7a1) and the Na(+)-independent organic anion transporter 2 (Oatp2).

23 is the major regulator of the Na+-dependent organic anion transporter 2.

24 of compound in the kidneys mediated by human organic anion transporter 3 (hOAT3) was hypothesized as

25 ried out a targeted disruption of the murine organic anion transporter 3 (Oat3) gene.

26 In this study, mice lacking organic anion transporter 3 (Oat3) had a 10 to 15% lower

27 mate 80% decrease in the expression level of organic anion transporter 3 (SLC22a8).

28 Human organic anion transporter 4 (hOAT4) belongs to a superfa

29 +) taurocholate cotransporter, multispecific organic anion transporter, and P-glycoprotein) were also

30 n 1 (MRP1) and the canalicular multispecific organic anion transporter (cMOAT or MRP2) are ATP-bindin

31 protein (MRP) and canalicular multispecific organic anion transporter (cMOAT) are closely related ma

32 ctive in the liver canalicular multispecific organic anion transporter (cMOAT) protein.

33 protein (MRP)1 and canalicular multispecific organic anion transporter (cMOAT)/MRP2 are ATP-binding c

34 ) (a substrate for canalicular multispecific organic anion transporter [cMOAT]).

35 These results identify an organic anion transporter composed of a putative seven-h

36 er fatty acid binding proteins (L-FABP), and organic anion transporters--determine the distribution,

37 ing is independently correlated with hepatic organic anion transporter expression.

38 ily 10 member 1 (Slc10a1) and solute carrier organic anion transporter family member (Slco) 1a1 and 1

39 rritin light chain (FTL), and solute carrier organic anion transporter family member 2B1 (SLCO2B1), i

40 the structure-function relationships of the organic anion transporter family.

41 the structure-function relationships of the organic anion transporter family.

42 ocation of organic anions by a member of the organic anion transporter family.

43 uggests the presence of distinctly different organic anion transporters for the efflux of VPA at the

44 We have previously cloned a cDNA encoding an organic anion transporter from mouse kidney (mOAT).

45 These cells had organic anion transporter function.

46 nce was associated with polymorphisms in the organic anion transporter gene SLCO1B1 (P = 2.1 x 10(-11

47 Human organic anion transporter hOAT1 belongs to a superfamily

48 Human organic anion transporter hOAT1 plays critical roles in

49 The human organic anion transporter (hOAT1) is a key component in

50 a role in the functional maturation of human organic anion transporter hOAT4.

51 In contrast to the organic anion transporters identified to date, a transpo

52 7-kDa membrane-associated protein; cMOAT, an organic anion transporter implicated in multidrug resist

53 Organic anion transporters in the kidney proximal tubule

54 ne of direct evidence implicating one of the organic anion transporters in the uptake of a mercuric c

55 city, and circumstantial evidence implicates organic anion transporters in these processes.

56 inhibited in the presence of probenecid, an organic anion transporter inhibitor.

57 translational modification of a mouse kidney organic anion transporter (mOAT), in a mammalian cell sy

58 P-glycoprotein (P-gp) and the multispecific organic anion transporter (MOAT), the liver-specific hom

59 transport in COS-7 cells expressing a mouse organic anion transporter (mOAT1), suggesting an importa

60 In vivo studies implicate the organic anion transporter (OAT) family as a pivotal comp

61 assessment of the contributions of specific organic anion transporter (OAT) family members to detoxi

62 rate) include two "drug" transporters of the organic anion transporter (OAT) family: OAT1 (SLC22A6, o

63 mal tubule cells by the basolateral membrane organic anion transporters (Oat) 1 and Oat3.

64 Renal organic anion transporters (OAT) are known to mediate th

65 Organic anion transporters (OAT) play essential roles in

66 The organic anion transporters OAT1 (SLC22A6) and OAT3 (SLC2

67 The organic anion transporters OAT1 (SLC22A6, originally ide

68 organic cation transporters (OCT2 and OCT3), organic anion transporter (OAT1), and monoamine transpor

69 The organic anion transporter OAT4 (SLC22A11) and organic an

70 ferences and transport function of olfactory organic anion transporter, Oat6, in comparison with the

71 Organic anion transporters (OATs) and organic cation tra

72 Organic anion transporters (OATs) are believed to mediat

73 Organic anion transporters (Oats) are located in the bar

74 min, fatty acid binding proteins (FABPs) and organic anion transporters (OATs) have been identified a

75 Studies of the organic anion transporters (Oats) have focused mainly on

76 Given the selective expression of organic anion transporters (OATs) in renal proximal tubu

77 luding the proximal tubule-specific drug and organic anion transporters (OATs) OAT1 (SLC22a6) and OAT

78 Organic anion transporters (OATs) play a critical role i

79 Organic anion transporters (OATs) play a pivotal role in

80 With the cloning of multiple genes encoding organic anion transporters (OATs), the study of organic

81 s are secreted by the recently characterized organic anion transporters (OATs), which are expressed i

82 Organic anion transporters (OATs, SLC21) are important i

83 Organic anion transporters (OATs, SLC22) interact with a

84 Organic anion transporters play an essential role in eli

85 gnificant associations were with SNPs in the organic anion transporter polypeptide, SLCO1B1.

86 Rat organic anion transporter polypeptide1 (Oatp1) is known

87 stance-associated protein 2 (Mrp2/Abcc2), an organic anion transporter present in the apical membrane

88 tance-associated protein 2 (Mrp2, Abcc2), an organic anion transporter present in the apical membrane

89 ly keratinocytes expressed the organic anion organic anion transporter protein (OATP) 2B1 transporter

90 odium taurocholate cotransporter protein and organic anion transporter protein 1.

91 selectively taken up by a sodium-independent organic anion transporter protein-1B1 (OATP1B1) exclusiv

92 The rat organic anion transporter, rOAT3, mediates the transport

93 n and transport of organic anions by the rat organic anion transporter, rOAT3.

94 , as well as organic cation transporters and organic anion transporters Slc22a1 (Oct1), Slc22a2 (Oct2

95 trolled by URAT1 (SLC22A12), a member of the organic anion transporter superfamily.

96 oatp1 is an hepatic sinusoidal organic anion transporter that mediates uptake of variou

97 ase in the expression of rOat2 (Slc22a7), an organic anion transporter that regulates, in part, the t

98 The mechanisms that target organic anion transporters to different domains of the i

99 taurocholate cotransporter and multispecific organic anion transporter were more profoundly diminishe

100 ransporter hOAT1 belongs to a superfamily of organic anion transporters, which play critical roles in

101 porter 1 (hOAT1) belongs to a superfamily of organic anion transporters, which play critical roles in

102 substrates for the canalicular multispecific organic anion transporter whose activity has recently be

103 closely related to MRP, cMOAT, and the yeast organic anion transporter YCF1.