ライフサイエンスコーパス: organizing center

1 factor, or morphogen, that is secreted by an organizing center .

2 y recruited around the polarized microtubule-organizing center.

3 omes to distribute away from the microtubule-organizing center.

4 with the trans-Golgi network and microtubule-organizing center.

5 ation of CV membranes around the microtubule-organizing center.

6 e location of the centrosome meiotic-vegetal organizing center.

7 go on microtubules away from the microtubule-organizing center.

8 t the tip of the meristem and the underlying organizing center.

9 he centrosome, also known as the microtubule-organizing center.

10 transport on microtubules to the microtubule organizing center.

11 obular structure adjacent to the microtubule-organizing center.

12 appeared to concentrate over the microtubule organizing center.

13 umulation of mitochondria at the microtubule organizing center.

14 tissues, and a distal, mislocalized anterior organizing center.

15 rinuclear region, often near the microtubule-organizing center.

16 d the anterior neural ridge, another rostral organizing center.

17 ociated with microtubules at the microtubule organizing center.

18 adopts the function as cellular microtubule organizing center.

19 f an apical stem cell pool and an underlying organizing center.

20 ys in the absence of a dedicated microtubule-organizing center.

21 microtubule minus-end detachment from their organizing centers.

22 of multipolar spindles and free microtubule-organizing centers.

23 me organisms, for duplication of microtubule-organizing centers.

24 the duplication of a variety of microtubule organizing centers.

25 d by specialized cellular groups that act as organizing centers.

26 Nin localizes to noncentrosomal microtubule-organizing centers.

27 both Mbo1p and Gfh1p localize to microtubule organizing centers.

28 in PAR-2 in regions distant from microtubule organizing centers.

29 modulin-like proteins present in microtubule-organizing centers.

30 gnaling gradients that emanate from distinct organizing centers.

31 complexes localized at specific microtubule-organizing centers.

32 y of either centrosomes or other microtubule organizing centers.

33 le pole bodies (SPBs), the yeast microtubule organizing centers.

34 from the cell body and the main microtubule-organizing center?

35 at Golgi outposts serve as local microtubule-organizing centers [8] and secretory stations in dendrit

36 mber of gamma-tubulin-containing microtubule-organizing centers, a phenotype reminiscent of cells ove

37 tor, BRAVO (BRASSINOSTEROIDS AT VASCULAR AND ORGANIZING CENTER), acting as a cell-specific repressor

38 egation that led to acentrosomal microtubule-organizing center (aMTOC) formation and subsequent spind

39 to reside in the centrosome, or microtubule-organizing center, an amembranous organelle that regulat

40 Third, inhibition of microtubule organizing center and centrosome polarization impairs ne

41 We present evidence for a tip organizing center and confirm two of its main components

42 tin ring and polarization of the microtubule-organizing center and cytolytic granules to the center o

43 a recycling compartment near the microtubule organizing center and Golgi apparatus.

44 nstitutes a key component of the microtubule-organizing center and nucleates microtubule assembly.

45 entrosome functions as the major microtubule-organizing center and plays a vital role in guiding chro

46 nockdown of C19ORF5 disrupts the microtubule-organizing center and results in microtubule nucleation

47 ed an aster, which is nucleated by a central organizing center and spans the entire cytoplasm.

48 preading and polarization of the microtubule organizing center and the actin cytoskeleton were ineffi

49 We also establish a link between the tip organizing center and the filament-forming protein FilP.

50 sequently, the relocation of the microtubule organizing center and the Golgi apparatus in the directi

51 es with the ability to function as a vegetal organizing center and to coordinate the development of a

52 M2 inflammasomes colocalize with microtubule organizing centers and autophagosomes.

53 become competent to function as microtubule-organizing centers and basal bodies.

54 The organizing centers and molecules that pattern the cerebr

55 s, they failed to polarize their microtubule organizing centers and perforin-containing granules to t

56 Centrosomes are microtubule-organizing centers and play a dominant role in assembly

57 rm for investigating hRPe and hCPe as neural organizing centers and provide support for the model tha

58 ccumulation, polarization of the microtubule organizing center, and the convergence of cytolytic gran

59 At the core is the dermal papilla, the organizing center, and the epithelial stem cells that re

60 sosome-related organelles to the microtubule-organizing center, as an early step in the cell biologic

61 n of pM140 to an aggresome-like, microtubule organizing center-associated structure that is known to

62 hat the Caulobacter PopZ scaffold creates an organizing center at the cell pole that actively regulat

63 otubule overlaps associated with microtubule organizing centers at both interphase and mitosis.

64 cleosome packing mechanism creates chromatin organizing centers at the 5' ends of genes where importa

65 ganize a bipolar spindle without microtubule organizing centers at the poles.

66 uppression of activation impacts microtubule organizing center-based cytoskeletal rearrangement and g

67 uited to the cap of CD20 and the microtubule organizing center became polarized toward the cap.

68 accumulated in acentriolar microtubule (MT)-organizing centers but failed to adopt a higher-order st

69 ell-induced reorientation of the microtubule-organizing center, but is required for the subsequent ex

70 e ER is concentrated at the microtubule (MT)-organizing center by dynein and is spread by outward ext

71 to the centrosome (the principal microtubule organizing center) by minus-end-directed transport and t

72 bly occurs in the absence of the microtubule-organizing centers called centrosomes.

73 us end interactions from oppositely oriented organizing centers can provide the force for organelle t

74 ndosomes concentrated around the microtubule-organizing center/centrosome.

75 tmitotic karyoplasts assembled a microtubule-organizing center containing gamma-tubulin and pericentr

76 arin and dextran sulfate showed that pattern organizing centers correspond precisely with WntA, wingl

77 accumulation of 6-PGDase at the microtubule-organizing centers could be blocked by colchicine, sugge

78 d that, unlike the floor plate, these dorsal organizing centers develop in a patterned, segmental man

79 8), have been cornerstones in studies of how organizing centers differentially pattern tissues.

80 has important functions at the microtubular organizing center during cell division.

81 The reorientation of the microtubule organizing center during cell migration into a wound in

82 ain-hindbrain boundary (MHB) is a well-known organizing center during vertebrate brain development.

83 re that C19ORF5 localizes to the microtubule-organizing centers during microtubule regrowth after noc

84 st cells, lose their function as microtubule organizing centers during neuronal development.

85 Organizing centers emit signaling molecules that specify

86 Equatorial microtubule organizing center (eMTOC) activity was not affected in c

87 ecruit granzyme B+ granules, the microtubule-organizing center, F-actin, Wiskott-Aldrich syndrome pro

88 ranslocation of the virus to the microtubule-organizing center following endosome penetration.

89 n specificity directly but rather acts as an organizing center for a multitude of specificity interac

90 the morphogenetic furrow is a developmental organizing center for patterning and cell proliferation.

91 exchange protein (cdb3) serves as a critical organizing center for protein-protein interactions that

92 ivatives, including the prechordal plate, an organizing center for rostral development.

93 mmetric organisms, the midline is a critical organizing center for the developing central nervous sys

94 This suggests that the cilium serves as an organizing center for the early steps of the signal tran

95 The intercalated disc serves as an organizing center for various cell surface components at

96 The organizing centers for Drosophila imaginal disc developm

97 roof plate and choroid plexus are essential organizing centers for inducing dorsal neuron fates and

98 sterol and are believed to be highly dynamic organizing centers for receptors and their cognate signa

99 Lipid raft microdomains act as organizing centers for signal transduction.

100 molecules, which suggests that they serve as organizing centers for the activation of NF-kappaB.

101 zation, tubulin multimerization, microtubule organizing center formation, calcium/calmodulin signalin

102 hat, after decapitation, planarians build an organizing center from stem cells at the old midline tha

103 gamma-tubulin complexes to microtubule (MT)-organizing centers from yeast to human cells.

104 rotate in the same direction around a common organizing center) have not been demonstrated and studie

105 Centrosomes are the major microtubule-organizing center in animal cells.

106 The centrosome is the dominant microtubule-organizing center in animal cells.

107 ear sites as follows: around the microtubule organizing center in association with the cis-Golgi and

108 tes the size of the WUSCHEL (WUS)-expressing organizing center in inflorescence meristems.

109 The centrosome is the major microtubule organizing center in mammalian cells.

110 artment (ERC), which is near the microtubule-organizing center in many cell types.

111 V-1) disrupts the centrosome, the primary MT organizing center in many cell types.

112 ic spindle lacks a centrosome or microtubule-organizing center in many organisms.

113 lusters that colocalize with the microtubule-organizing center in patient cells.

114 e spindle pole body (SPB) is the microtubule organizing center in Saccharomyces cerevisiae.

115 keletal filaments radiate from a microtubule organizing center in the cVAC.

116 The roof plate is an organizing center in the dorsal CNS that controls specif

117 ve along microtubules toward the microtubule-organizing center in the minus-end direction.

118 signal from the stem cell population to the organizing center in the underlying cells.

119 rosome, serves as the major microtubule (MT) organizing center in the yeast cell.

120 romosomes radiated away from the microtubule-organizing centers in a prometaphase-like pattern rather

121 centrosomes are major microtubule organizing centers in animal cells, and they comprise a

122 Centrosomes are the main microtubule-organizing centers in animal cells.

123 only a few conserved proteins at microtubule-organizing centers in animals, plants, and flagellate pr

124 eutrophils but is found near the microtubule-organizing centers in cells from pregnant women.

125 inductive and trophic activities of rostral organizing centers in early development of the mammalian

126 Centrosomes are the principal microtubule organizing centers in eukaryotic cells and centrosome du

127 hat is an essential component of microtubule-organizing centers in many organisms ranging from yeast

128 goes retrograde transport to the microtubule-organizing centers in neutrophils from pregnant women.

129 rin is an essential component of microtubule-organizing centers in organisms ranging from algae and y

130 atterning and underscore the significance of organizing centers in patterning the vertebrate neural p

131 Organizing centers in the developing brain provide an as

132 activity of multiple acentriolar microtubule organizing centers in the oocyte.

133 e positioning of the centrosome (microtubule organizing center) in the leading process in front of th

134 ibutable to loss of signaling from forebrain-organizing centers including Fgf8 from the anterior neur

135 Nucleating from MT-organizing centers, including but by no means limited to

136 ons of distal and proximal stem cells and an organizing center known as the quiescent center.

137 he behavior of the fission yeast microtubule-organizing center (known as the spindle pole body or SPB

138 ule arrays without a conspicuous microtubule organizing center like a centrosome.

139 ants lack a structurally defined microtubule-organizing center like the centrosome, organization of t

140 HC complexes, lytic granules and microtubule organizing center localization into synaptic areas are s

141 ranscriptionally silent EPODs as the elusive organizing centers, long proposed to topologically isola

142 ost rostral cranial vessels and the midbrain organizing center (MOC) which gives rise to the posterio

143 Microtubule-organizing centers move from centrosomes to the nuclear

144 microtubules but focuses to the microtubule organizing center (MTOC) after NK cell activation, when

145 ization, and polarization of the microtubule organizing center (MTOC) and cytolytic granules to the N

146 udy, we report that, whereas the microtubule organizing center (MTOC) and cytosolic granules follow t

147 ich involve reorientation of the microtubule organizing center (MTOC) and Golgi apparatus toward the

148 orous vacuole (inclusion) to the microtubule-organizing center (MTOC) and promotes its fusion with ly

149 some." This centrosome acts as a microtubule organizing center (MTOC) and remains stationary, forming

150 t granule concentration near the microtubule-organizing center (MTOC) and subsequent delivery by the

151 movement of vesicles toward the microtubule organizing center (MTOC) and translocation of the MTOC t

152 lytic granule convergence to the microtubule-organizing center (MTOC) as an early, prerequisite step

153 utants do not retain a discrete posterior MT organizing center (MTOC) capable of supporting ectopic p

154 The centrosome acts as the microtubule-organizing center (MTOC) during mitosis in animal cells.

155 FA1 polarization, spreading, and microtubule organizing center (MTOC) formation in NK cells.

156 es significant separation of the microtubule organizing center (MTOC) from the nuclear envelope.

157 triolar material, is the primary microtubule-organizing center (MTOC) in animal cells.

158 The centrosome is the major microtubule organizing center (MTOC) in dividing cells and in many p

159 arization and recruitment of the microtubule organizing center (MTOC) in HIV-1-infected cells.

160 lly located distal from the microtubule (MT)-organizing center (MTOC) in IQGAP1-deficient cells.

161 The nucleus is the main microtubule-organizing center (MTOC) in muscle cells due to the accu

162 The microtubule-organizing center (MTOC) is reoriented between the nucle

163 g edge and, surprisingly, to the microtubule organizing center (MTOC) of migrating fibroblasts.

164 e for CENP-F at the centrosome, the major MT organizing center (MTOC) of the cell.

165 otein, moves cargo away from the microtubule-organizing center (MTOC) on microtubules.

166 h actin reorganization preceding microtubule-organizing center (MTOC) polarization to the synapse.

167 ncluding increased calcium flux, microtubule organizing center (MTOC) polarization, phosphorylation o

168 ll killing in part through its effects on MT organizing center (MTOC) polarization.

169 d the location of the centrosome/microtubule organizing center (MTOC) relative to the cell nucleus an

170 and acetylation of MTs emanating from the MT-organizing center (MTOC) shortly after viral entry and m

171 l complex that contains a unique microtubule-organizing center (MTOC) that organizes the cytoskeleton

172 lymphocytes, polarization of the microtubule-organizing center (MTOC) to the immunological synapse en

173 t is required for connecting the microtubule organizing center (MTOC) to the nucleus.

174 al synapse, translocation of the microtubule-organizing center (MTOC) to the synapse, and focused sec

175 L) requires translocation of the microtubule organizing center (MTOC) to the target cell contact site

176 , signal the polarization of the microtubule organizing center (MTOC) together with cytolytic granule

177 Polarization of the T cell microtubule-organizing center (MTOC) toward the antigen-presenting c

178 The reorientation of the T cell microtubule-organizing center (MTOC) toward the antigen-presenting c

179 as well as reorientation of the microtubule-organizing center (MTOC) toward the APC.

180 splitting and separation of the microtubule-organizing center (MTOC) well before nuclear envelope br

181 by analyzing the position of the microtubule-organizing center (MTOC), as it moves toward the interfa

182 ore, blocked the movement of the microtubule organizing center (MTOC), granzyme B (a component of cyt

183 ely constant localization at the microtubule-organizing center (MTOC), Nuf is present at the MTOC onl

184 hr505) co-localized with two key microtubule organizing center (MTOC)-associated proteins, pericentri

185 lgi itself functions as an unconventional MT-organizing center (MTOC).

186 , the initiation of the daughter microtubule organizing center (MTOC).

187 sembly takes place near the host microtubule-organizing center (MTOC).

188 e the cell nucleus) known as the microtubule organizing center (MTOC).

189 MTs and inducing the reorientation of the MT organizing center (MTOC).

190 membranes and apparently at the microtubule-organizing center (MTOC).

191 on by linking the nucleus to the microtubule organizing center (MTOC).

192 moves to and associates with the microtubule organizing center (MTOC).

193 ex (gamma-TuC), and composes the microtubule organizing center (MTOC).

194 on the later polarization of the microtubule-organizing center (MTOC).

195 ls involves reorientation of the microtubule organizing center (MTOC).

196 EC directional migration and mislocalized MT organizing center (MTOC)/Golgi and myosin IIB cell rear

197 crotubule- (MT) and centrosome- [microtubule organizing center (MTOC)] associated protein that regula

198 Moreover, the microtubule-organizing center (MTOC, or centrosome), which rapidly r

199 A can stimulate the formation of microtubule organizing centers (MTOC) on its own.

200 somes, but more diverse types of microtubule organizing centers (MTOCs) also exist, especially in dif

201 OZART1, Mzt1/Tam4, is located at microtubule-organizing centers (MTOCs) and coimmunoprecipitates with

202 ts gamma-TuCs specifically to cytoplasmic MT organizing centers (MTOCs) and interphase MTs.

203 C becomes active specifically at microtubule-organizing centers (MTOCs) and not more broadly througho

204 In young embryos, hundreds of microtubule-organizing centers (MTOCs) are assembled completely from

205 Microtubule-organizing centers (MTOCs) are large, multi-subunit prot

206 ously that centrosomes and other microtubule-organizing centers (MTOCs) attach to the apical intermed

207 Non-centrosomal microtubule organizing centers (MTOCs) direct microtubule (MT) organ

208 Microtubule-organizing centers (MTOCs) form, anchor, and stabilize t

209 a) family members associate with microtubule-organizing centers (MTOCs) from yeast to humans, but the

210 gamma-tubulin and pericentrin at microtubule-organizing centers (MTOCs) in mouse oocytes arrested at

211 A-tagged GTU1p localizes to four microtubule-organizing centers (MTOCs) in vegetative cells: basal bo

212 Positioning of microtubule-organizing centers (MTOCs) incorporates biochemical and

213 the spindle that can persist as microtubule organizing centers (MTOCs) into interphase.

214 Microtubule-organizing centers (MTOCs) nucleate microtubules that ca

215 Regulation of microtubule organizing centers (MTOCs) orchestrates the reorganizati

216 e in microtubule nucleation from microtubule organizing centers (MTOCs) such as the animal centrosome

217 epithelial cells, attachment of microtubule-organizing centers (MTOCs) to intermediate filaments (IF

218 larization of lytic granules and microtubule-organizing centers (MTOCs) toward the immune synapse bet

219 embled from randomly distributed microtubule-organizing centers (MTOCs) without centrioles, because o

220 rom noncentrosomal intracellular microtubule organizing centers (MTOCs), although such structures rem

221 Microtubule-organizing centers (MTOCs), known as centrosomes in anim

222 etosomes, centrosomes, and other microtubule organizing centers (MTOCs), whether by direct filiation

223 core structure of centrosomes or microtubule-organizing centers (MTOCs).

224 Centrosomes are primary microtubule (MT)-organizing centers (MTOCs).

225 he de novo formation of multiple microtubule-organizing centers (MTOCs).

226 ted proteins present at specific microtubule organizing centers (MTOCs).

227 centrin and gamma-tubulin within microtubule organizing centers (MTOCs).

228 gregates were not transported to microtubule organizing centers (MTOCs).

229 acterized by the loss of obvious microtubule organizing centers (MtOCs).

230 gamma-tubulin complexes to microtubule (MT) organizing centers (MTOCs).

231 ymmetrically dividing cells, the microtubule-organizing centers (MTOCs; mammalian centrosome and yeas

232 rtical anchor for noncentrosomal microtubule organizing centers (ncMTOCs) in the Drosophila oocyte.

233 iption factor produced in cells of the niche/organizing center (OC) of shoot apical meristems.

234 containing vacuoles close to the microtubule organizing center of infected epithelial cells.

235 The centrosome is the major microtubule-organizing center of most mammalian cells and consists o

236 e spindle pole body (SPB) is the microtubule organizing center of Saccharomyces cerevisiae.

237 which is normally expressed in the stem cell organizing center of shoot meristems.

238 The centrosome is the primary microtubule organizing center of the cells and templates the formati

239 nterior neural ridge (ANR), which acts as an organizing center of the forebrain by producing FGF8 mor

240 Centrosomes are the microtubule-organizing centers of animal cells that organize interph

241 number of centrosomes, the major microtubule-organizing centers of animal cells, is critical for the

242 ntrioles represent the principal microtubule organizing centers of animal cells.

243 hat build centrosomes, the major microtubule-organizing centers of animal cells.

244 It is found in microtubule-organizing centers of organisms ranging from algae and y

245 tor HNF3beta/FoxA2 is expressed in embryonic organizing centers of the gastrulating mouse, frog, fish

246 A scroll's behavior is embodied in its organizing center or filament, a largely quiescent tube

247 ltaNLS mutant was blocked at the microtubule organizing center or immediately upstream of nuclear por

248 ericentriolar sites close to the microtubule organizing center or in specialized nuclear domains call

249 tructures either adjacent to the microtubule-organizing center or widely distributed in the cytoplasm

250 ation of the two proteins in the microtubule organizing center, our results suggest that centrin is c

251 elle that functions as the major microtubule-organizing center, plays an essential role in the format

252 Surprisingly, microtubule organizing center polarity at the IS, which does not dep

253 thymocyte development as well as microtubule organizing center polarization and cytolytic function in

254 Microtubule organizing center polarization and granule reorientation

255 s range significantly suppressed microtubule organizing center polarization and granzyme B release in

256 e contact site with APC, altered microtubule-organizing center polarization and the IS structure, and

257 le secretion and by showing that microtubule organizing center polarization is dispensable for effici

258 d for conjugate formation, MTOC (microtubule organizing center) polarization, and NKG2D-dependent cel

259 ive CD8(+) T cells polarized the microtubule organizing center, produced IL-2, proliferated, and diff

260 tatic Golgi elements, associated with the MT-organizing center proteins gamma-tubulin and pericentrin

261 aling within and between these two embryonic organizing centers remained intact in FN-null mutants.

262 ase and diacylglycerol-dependent microtubule organizing center reorientation, while depleting the poo

263 at the T cell/APC interface, the microtubule organizing center reoriented toward it.

264 The basal body is a microtubule-organizing center responsible for organizing the cilium,

265 rs of bilateral clusters include the rostral organizing center (ROC) which gives rise to the most ros

266 -strands and two alpha-helices with the zinc organizing center showing remote resemblance to the treb

267 the action of mediators released from nearby organizing centers, such as the floor plate and paraxial

268 al meristem is composed of the quiescent (or organizing) center surrounded by stem (initial) cells fo

269 differentiation by limiting the size of the organizing center that maintains stem cell identity in n

270 he floor plate, an essential ventral midline organizing center that produces the morphogen Shh, has d

271 Centrosomes are key microtubule-organizing centers that contain a pair of centrioles, co

272 is, we demonstrate the presence of forebrain organizing centers that express secreted growth factors,

273 Centrosomes are microtubule-organizing centers that facilitate bipolar mitotic spind

274 till speculative, lack the major microtubule organizing centers that most cells use to assemble and p

275 arallel color stripes mirrored around linear organizing centers that run between the anterior and pos

276 es-distinct from elements of the microtubule-organizing center-that is required for the somatic cell

277 onic organizer and for formation of the head organizing center (the anterior mesendoderm, or AME).

278 Our studies identify a new core organizing center, the assembly zone that controls aECM

279 re organized with plus-ends away from the MT organizing center, the regulation of non-centrosomal MT

280 the importance of centrosomes as microtubule-organizing centers, the mechanism and regulation of PCM

281 s states that centrosomes act as microtubule-organizing centers throughout the cell cycle.

282 as indicated by a failure of the microtubule-organizing center to align with the direction of cell mi

283 arrays at the cell cortex without a central organizing center to anchor the microtubule ends.

284 t the trans-Golgi network as an alternate MT organizing center to facilitate virus spread.

285 fenestration to enable a single microtubule organizing center to nucleate both cytoplasmic and nucle

286 es emanating from the equatorial microtubule-organizing center to position the nuclei away from the c

287 F5 plays a role in anchoring the microtubule-organizing center to the centrosomes.

288 and induce reorientation of the microtubule-organizing center to the immunologic synapse (IS).

289 mined by the polarization of the microtubule-organizing center to the immunological synapse.

290 A-4 and the reorientation of the microtubule-organizing center to the site of T-cell receptor engagem

291 cted cells did not begin to lose microtubule-organizing centers until 13 hpi.

292 PLK1, and gamma-tubulin) to the microtubule-organizing center via the RhoA signaling pathway.

293 unsuccessful polarization of the microtubule-organizing center, which alters the polarity of the rece

294 is determined in most cells by a microtubule-organizing center, which nucleates microtubule assembly

295 Among such structures are actin-organizing centers, which mediate the movement of certai

296 resulted from molecular reprogramming of an organizing center whose activity controls outgrowth and

297 showed the formation of multiple microtubule organizing centers with Aurora kinase A and gamma-tubuli

298 e posterior establishment of the microtubule organizing center within the presumptive oocyte.

299 EL (WUS) transcription factor establishes an organizing center within the shoot meristem that is esse

300 a model system for understanding microtubule organizing centers, yet very little is known about the m