ライフサイエンスコーパス: organophosphate

1 2+) with each other and with each individual organophosphate.

2 resistant to pyrethroids but susceptible to organophosphates.

3 DDT) but fully susceptible to carbamates and organophosphates.

4 may be associated with exposure to specific organophosphates.

5 el for carbamates and full susceptibility to organophosphates.

6 n preventing lipid oxidation and detoxifying organophosphates.

7 ated pesticides and have ongoing exposure to organophosphates.

8 hemical biosensor for paraoxon as a model of organophosphates.

9 fipronil have been used as replacements for organophosphates.

10 or chlorpyrifos, 2.3 (95% CI: 0.98, 5.3) for organophosphates, 2.1 (95% CI: 0.9, 4.8) for pyrethroids

11 rylation rate constant k(OP) for the neutral organophosphate 7-[(methylethoxyphosphonyl)oxy]-4-methyl

12 h standard deviation increase of use for two organophosphates (acephate and oxydemeton-methyl) and th

13 nd manganese fungicides) and five individual organophosphates (acephate, chlorpyrifos, diazinon, mala

14 The organophosphate acid anhydrolase (OPAA) is a member of a

15 After organophosphate addition, BSP accumulates within these B

16 that the enzyme may be resistant to dead-end organophosphate aging reactions that permanently inactiv

17 only in primates, are reactive to nonpeptide organophosphate and alkylamine antigens secreted by bact

18 n be explained in part by exposure of GWV to organophosphate and carbamate acetylcholinesterase inhib

19 Acute organophosphate and carbamate pesticide poisonings resul

20 ion of organochlorine, synthetic pyrethroid, organophosphate and carbamate pesticide residues in frui

21 rase biosensor and its application to detect organophosphate and organocarbamate pesticides.

22 ive material for the efficient adsorption of organophosphate and organophosphonate species.

23 le uranium phosphates via the addition of an organophosphate and promote the development of reducing

24 g metabolic resistance (carboxylesterase) to organophosphates and carbamates in aphids, can have dele

25 Gut microbes were shown to degrade organophosphates and cause intestinal dysfunction.

26 f traces of different pesticides (triazinic, organophosphates and chlorurates) present in hydrophobic

27 many of the same neuropeptide targets as the organophosphates and concordance analysis showed signifi

28 anti-electrostatic anion-anion homodimers of organophosphates and cyanostar macrocycles was investiga

29 ent catalysts of the breakdown of neurotoxic organophosphates and have great potential as both biothe

30 t microbiome-mediated diabetogenic nature of organophosphates and hence that the usage of these insec

31 r nerve targets are acetylcholinesterase for organophosphates and methylcarbamates, the nicotinic ace

32 arget for the developmental neurotoxicity of organophosphates and other neurotoxicants, and further,

33 Organophosphates and pyrethroids are the most common cla

34 on SVOCs (e.g., brominated flame retardants, organophosphates, and phthalates) and in house dust extr

35 pollutants including hazardous nitrophenols, organophosphates, and polychlorinated arenes and hydroca

36 estational pesticide exposures, particularly organophosphates, and provides novel results of ASD and

37 P for organisms that cannot directly access organophosphates, and thereby increase marine biological

38 -S variant, which is the target of poisonous organophosphate anticholinesterase insecticides such as

39 Organophosphates are the most frequently and largely app

40 r 550 (FM 550), Firemaster 600 (FM 600), and organophosphate aryl ester technical mixtures have been

41 rvation response mutants on media containing organophosphates as the only source of phosphorus.

42 AChE is inactivated by organophosphates as they pass through the P-site and pho

43 Proximity to organophosphates at some point during gestation was asso

44 as diminuta, catalyzes the detoxification of organophosphate-based insecticides and chemical warfare

45 osphate (TDCIPP) is a high-production volume organophosphate-based plasticizer and flame retardant wi

46 cally to the P-site and block the passage of organophosphates but not acetylcholine.

47 A mechanism for the hydrolysis of organophosphates by the bacterial PTE has been proposed.

48 ive potentially neurotoxic pesticide groups (organophosphates, carbamates, pyrethroids, neonicotinoid

49 Most of the organophosphate chemical warfare agents are a mixture of

50 Organophosphate chemicals (OPs), which form the basis of

51 s elevated among women who had ever used the organophosphates chlorpyrifos [HR=1.4 (95% CI: 1.0, 2.0)

52 ore the targeting of neuroactive peptides by organophosphates (chlorpyrifos, diazinon), an organochlo

53 We compared organophosphates (chlorpyrifos, diazinon), an organochlo

54 neonicotinoid, imidacloprid, but not by the organophosphate chlorpyriphos, which does not affect NF-

55 The organophosphate class of compounds includes common herbi

56 essed with cumulative exposure scores for 34 organophosphates combining an historical crop-exposure p

57 FM550 and its organophosphate components increased human PPARgamma1 tr

58 nted of PAF acetylhydrolase reacted with the organophosphate compound paraoxon via its active site Se

59 al flame retardant mixture of brominated and organophosphate compounds applied to polyurethane foam u

60 Organophosphate compounds are heavily used in agricultur

61 NTE reacts with organophosphate compounds that cause a paralyzing axonal

62 rapid, sensitive and selective detection of organophosphates compounds.

63 fine Utah dirt sample as a model system for organophosphate-contaminated soil.

64 The pyrethroid tau-fluvalinate and the organophosphate coumaphos have been used for Varroa cont

65 anophosphate hydrolase (OPH), encoded by the organophosphate degradation (opd) island, hydrolyzes the

66 In previous studies of the organophosphate degradation gene cluster, we showed that

67 tabolomic analyses reveal that gut microbial organophosphate degradation produces short chain fatty a

68 lactonase (PLL) family that show promiscuous organophosphate-degrading activity.

69 phate-induced hyperglycemia, mediated by the organophosphate-degrading potential of gut microbiota.

70 iated enzyme that plays an important role in organophosphate detoxification and prevention of atheros

71 and other data indicate that paraoxonase, an organophosphate-detoxifying enzyme whose natural substra

72 Sex-specific effects of organophosphate diazinon on the gut microbiome and its m

73 to facilitate transport of Pigenerated from organophosphates due to the combined action of OPH and p

74 phosphate) were readily degraded into a mono-organophosphate (e.g., adenosine monophosphate) during h

75 The presence of organophosphate ester (OPE) flame retardants and plastic

76 that mimic the properties of the more common organophosphate ester metabolite yet are not readily deg

77 Levels of 13 organophosphate esters (OPEs) and 45 brominated and chlo

78 Volatile methylsiloxanes (VMSs) and organophosphate esters (OPEs) are two suites of chemical

79 Organophosphate esters (OPEs) are widely used as flame r

80 ters, brominated flame retardants (BFRs) and organophosphate esters (OPEs) by clothing from indoor ai

81 dants (AFRs), such as FireMaster 550, and of organophosphate esters (OPEs) has increased.

82 Many organophosphate esters (OPEs) have been reported to prim

83 The concentrations of six organophosphate esters (OPEs) in atmospheric particle ph

84 Organophosphate esters (OPEs) including triphenyl phosph

85 Fourteen organophosphate esters (OPEs) were measured in the filte

86 These flame retardants included organophosphate esters (OPEs), brominated flame retardan

87 s polybrominated diphenyl ethers (PBDEs) and organophosphate esters (OPEs), which were not manufactur

88 s of flame retardants: brominated (BFRs) and organophosphate esters (OPEs).

89 tember 21-28, 2013) and were analyzed for 12 organophosphate esters (OPEs; current-use plasticizers a

90 domonas diminuta catalyzes the hydrolysis of organophosphate esters at rates close to the diffusion l

91 the direct nucleophile in the hydrolysis of organophosphate esters by PTE.

92 ving sugars, nucleic acids, amino acids, and organophosphate esters.

93 yzing a broad range of substrates, including organophosphates, esters, and carbonates.

94 We studied the association between organophosphate exposure and cognitive performance in vi

95 Two reports agree that increased levels of organophosphate exposure in utero result in greater numb

96 elopmental disorder with increased levels of organophosphate exposure.

97 ging strategy in protection and treatment of organophosphate exposure.

98 pidemiologic evidence has focused largely on organophosphate exposures, while research on other pesti

99 The organophosphate flame retardant, triphenyl phosphate (TP

100 mobisphenol A (TBBPA), and three chlorinated organophosphate flame retardants (ClOPFRs), tris(1,3-dic

101 gates the occurrence of 37 organohalogen and organophosphate flame retardants (FRs) from Norwegian ho

102 s), and emerging flame retardants, including organophosphate flame retardants (OPEs).

103 The occurrence and fate of 14 triester organophosphate flame retardants (OPFRs) and plasticizer

104 ng chlorinated alkyl and nonchlorinated aryl organophosphate flame retardants (OPFRs) as well as arom

105 Organophosphate flame retardants (OPFRs) had the highest

106 Organophosphate flame retardants (OPFRs) were the most c

107 in an increased use of and human exposure to organophosphate flame retardants (OPFRs).

108 Organophosphate flame retardants (PFRs) are becoming pop

109 Organophosphate flame retardants (PFRs) are widely used

110 rom animal studies suggests that exposure to organophosphate flame retardants (PFRs) can disrupt endo

111 Organophosphate flame retardants (PFRs) have been propos

112 We compared the human exposure to organophosphate flame retardants (PFRs) via inhalation,

113 polyurethane foam are commonly treated with organophosphate flame retardants (PFRs), including tris(

114 . strain TCM1 that is capable of hydrolyzing organophosphate flame retardants was determined.

115 Chronic treatment of mice with organophosphate for 180 days confirms the induction of g

116 ed obstacle for proposed models of prebiotic organophosphate formation.

117 mothers, was as important for the intake of organophosphate FRs as dust ingestion.

118 In addition, a mixture of nonhalogenated organophosphate FRs that included triphenyl phosphate (T

119 Some of the most toxic organophosphates have been adapted for use as chemical w

120 Several organophosphates have been shown to interact as mixtures

121 onmental influence (e.g. from air pollution, organophosphates, heavy metals) in ASD, and some of the

122 e which consists of elastin-like-polypeptide-organophosphate hydrolase (ELP-OPH), bovine serum albumi

123 durans ), we designed an extremely efficient organophosphate hydrolase (OPH) with broad substrate spe

124 Organophosphate hydrolase (OPH), encoded by the organoph

125 Curiously, a promiscuous organophosphate hydrolase activity is observed in all th

126 toward the goal of engineering hCE1 into an organophosphate hydrolase and protein-based therapeutic

127 It has also been implicated as an organophosphate hydrolase, with the ability to hydrolyze

128 Organophosphate hydrolases are proficient catalysts of t

129 ed in the rational design of next-generation organophosphate hydrolases that are capable of selecting

130 active sites and guide the future design of organophosphate hydrolases that hydrolyze compounds with

131 promiscuity drove the parallel divergence of organophosphate hydrolases within these lactonase famili

132 s such as serum paraoxonase 1 (PON1) and the organophosphate-hydrolyzing lactonase SsoPox are unable

133 rapid detection and quantitation of relevant organophosphates in neutral water.

134 Mitigating the effects of organophosphates in our bodies is critical and yet an un

135 of diabetes among people directly exposed to organophosphates in rural India (n = 3080).

136 Compounds 1-3 dealkylated a series of organophosphates in stoichiometric reactions by breaking

137 TiO2NFs was employed to enrich organophosphates in the nanocomposite due to its strong

138 Organophosphates inactivate acetylcholinesterase by reac

139 One strategy to protect against organophosphate inactivation is to design cyclic ligands

140 talloenzyme that catalyzes the hydrolysis of organophosphates, including pesticides and chemical warf

141 f-target serine hydrolase inhibition include organophosphate-induced delayed neuropathy and disruptio

142 confirm the involvement of gut microbiota in organophosphate-induced glucose intolerance.

143 to understand the role of gut microbiota in organophosphate-induced hyperglycemia and to unravel the

144 gluconeogenesis as the key mechanism behind organophosphate-induced hyperglycemia, mediated by the o

145 ma murine AChE-R levels while minimizing the organophosphate-induced neuromuscular junction dismorpho

146 Malathion is the most common organophosphate insecticide applied in the United States

147 significantly (P<0.05) with exposure to the organophosphate insecticide fonofos, after correction fo

148 utants ofB. diminutafailed to grow using the organophosphate insecticide methyl parathion as sole sou

149 ol on apple crops was dominated by intensive organophosphate insecticide regimes to control tortricid

150 Chlorpyrifos is a widely used organophosphate insecticide that is a suspected developm

151 This substantially eliminated organophosphate insecticide use by 2001, replacing it wi

152 alities of the increasing organochlorine and organophosphate insecticide use in the United States pos

153 The commonly-used organophosphate insecticide, chlorpyrifos (CPF), impairs

154 ic acid; maternal rubella infection; and the organophosphate insecticide, chlorpyrifos.

155 The wide agricultural use of diazinon, an organophosphate insecticide, has raised serious environm

156 Prenatal exposure to chlorpyrifos (CPF), an organophosphate insecticide, is associated with neurobeh

157 The association for dichlorvos, another organophosphate insecticide, was not attenuated by chlor

158 th routine application of diazinon, a common organophosphate insecticide.

159 We compared two organophosphate insecticides (chlorpyrifos, diazinon) wi

160 ct modification was observed for three other organophosphate insecticides (coumaphos, terbufos, and p

161 The odds ratios for four organophosphate insecticides (terbufos, fonofos, chlorpy

162 yzes the triester bond found in a variety of organophosphate insecticides and nerve agents.

163 sults add to the emerging literature linking organophosphate insecticides and respiratory health and

164 organochlorine insecticide dieldrin; and the organophosphate insecticides diazinon, malathion, and pa

165 The involvement of organophosphate insecticides in cognitive disorders is s

166 viduals chronically exposed to low levels of organophosphate insecticides may present with subtle imp

167 mers of a number of synthetic pyrethroid and organophosphate insecticides on chiral selective columns

168 These include organophosphate insecticides that inhibit acetylcholines

169 Use of several organophosphate insecticides was associated with elevate

170 Three organophosphate insecticides were significantly associat

171 e observed association of organochlorine and organophosphate insecticides with diabetes is consistent

172 There have been reductions in use of organophosphate insecticides, largely by substitution wi

173 esticides, in particular, organochlorine and organophosphate insecticides, may be associated with inc

174 dation of the neurodevelopmental toxicity of organophosphate insecticides; documentation of links bet

175 Inherent AChE-R overproduction under organophosphate intoxication confers both short-term pro

176 ng both short- and long-term protection from organophosphate intoxication.

177 It measured urinary concentrations of organophosphate metabolites [dimethylphosphate (DMP), di

178 dichloro-2,2-bis-(p-chorophenyl)ethylene and organophosphate metabolites among cases and controls.

179 The dimethyl organophosphate metabolites had the highest 95th percent

180 phosphates, histidinol phosphate, and common organophosphate metabolites.

181 noids imidacloprid and clothianidin, and the organophosphate miticide coumaphos oxon, cause a depolar

182 icotinoids (nicotinic receptor agonists) and organophosphate miticides (acetylcholinesterase inhibito

183 nsport and intracellular hydrolysis of small organophosphate molecules is an important mechanism for

184 d for Pd-catalyzed ortho-acetoxylation using organophosphates, namely, benzylic phosphonic and aryl p

185 al system for separating and detecting toxic organophosphate nerve agent compounds, based on the coup

186 portant development in countering weaponized organophosphate nerve agents and detecting commercially-

187 atalyzes the hydrolysis of a wide variety of organophosphate nerve agents and insecticides.

188 talloenzyme that catalyzes the hydrolysis of organophosphate nerve agents at rates approaching the di

189 acetylcholinesterase with the same series of organophosphate nerve agents was also measured.

190 een isolated that catalyze the hydrolysis of organophosphate nerve agents with high-rate enhancements

191 important anaytes (nitroaromatic explosives, organophosphate nerve agents, phenols).

192 efficient enzymes for the detoxification of organophosphate nerve agents.

193 are examined for their ability to hydrolyze organophosphate nerve agents.

194 report a route to synthesize a wide range of organophosphates of biological significance in a deep eu

195 in some populations frequently treated with organophosphates, old and new control options are being

196 e Smu. 1393c catalyzes the hydrolysis of the organophosphate omethoate (kcat/Km of (2.0 +/- 1.3) x 10

197 to determine the effect of exposure such as organophosphates on central nervous system, which alters

198 bstrates and explores the effect of selected organophosphates on their enzyme mimetic activity.

199 been shown to exhibit activity against both organophosphate (OP) and lactone compounds.

200 We analyzed those samples for 19 organophosphate (OP) and pyrethroid pesticides.

201 ed electrodes to construct a novel gas phase organophosphate (OP) biosensor.

202 rMoAChE that was phosphorylated by the four organophosphate (OP) compounds tested.

203 ped as a tool for biomonitoring exposures to organophosphate (OP) compounds, e.g., insecticides and c

204 of acetylcholinesterase (AChE) inhibition by organophosphate (OP) compounds.

205 Organophosphate (OP) esters bind covalently to the activ

206 Early-life organophosphate (OP) exposures elicit neurobehavioral de

207 Although recent usage of organophosphate (OP) flame retardants has increased subs

208 rase activity but are unusually resistant to organophosphate (OP) inhibitors.

209 and are implicated in the detoxification of organophosphate (OP) insecticides.

210 Intoxication by organophosphate (OP) nerve agents and pesticides should

211 he possible effect of early-life exposure to organophosphate (OP) on pediatric respiratory health is

212 An electrochemical sensor for detection of organophosphate (OP) pesticides and nerve agents using z

213 Widely used organophosphate (OP) pesticides can induce oxidative str

214 is limited that long-term human exposure to organophosphate (OP) pesticides, without poisoning, is a

215 g bioscavenger candidate to treat or prevent organophosphate (OP) poisoning.

216 A new class of amidine-oxime reactivators of organophosphate (OP)-inhibited cholinesterases (ChE) was

217 AChE) intended to catalyze the hydrolysis of organophosphate (OP)-inhibited hAChE in the CNS.

218 binding constant for organophosphonates and organophosphates (OPPs) of K=2x10(6) M-1.

219 n, and VX, monitoring the decontamination of organophosphates (OPs) by OPH and determining serum para

220 Organophosphates (OPs) inhibit acetylcholinesterase (ACh

221 ly mandated phase-out of residential uses of organophosphates (OPs), use of and potential for human e

222 utyrylcholinesterase, are primary targets of organophosphates (OPs).

223 enzyme may prove useful in the detection of organophosphates or exposure to cholinesterase inhibitor

224 shows no cross-reaction with other analogous organophosphates or metal salts.

225 ganochlorine [OR=2.7 (95% CI: 1.8, 4.0)] and organophosphate [OR=2.0 (95% CI: 1.3, 3.0)] insecticides

226 cides, and fumigants) or chemical structure (organophosphates, organochlorines, and carbamates) with

227 cal properties, with IC50 = 10(-7) M for the organophosphate paraoxon, similar to mammalian cell cult

228 ted to contribute to wheeze, paraquat, three organophosphates (parathion, malathion, and chlorpyrifos

229 d (dexamethasone, used in preterm labor), an organophosphate pesticide (chlorpyrifos), or nicotine.

230 Organophosphate pesticide (OP) exposure to the U.S. popu

231 e element confers increased resistance to an organophosphate pesticide and has spread in D. melanogas

232 The sensor was applied to detect the sample organophosphate pesticide ethylparaoxon and organocarbam

233 Research on organophosphate pesticide exposure and neurodevelopment

234 ential adverse associations with gestational organophosphate pesticide exposure, or that dietary expo

235 Organophosphate pesticide exposures, nitric oxide syntha

236 additional evidence that prenatal levels of organophosphate pesticide metabolites are associated wit

237 nts to test the system were chlorpyrifos, an organophosphate pesticide, and tetrabromobisphenol A, a

238 vity of AChE is inhibited by the presence of organophosphate pesticides (OPPs), the subsequent thioch

239 tive monitoring of p-nitrophenyl substituted organophosphate pesticides (OPs) in aqueous system was d

240 nsor was successfully used to quantify three organophosphate pesticides (OPs) in milk samples.

241 the detection and discrimination of several organophosphate pesticides (OPs).

242 ts ability to catalyze the detoxification of organophosphate pesticides and chemical warfare agents.

243 no associations between prenatal exposure to organophosphate pesticides and cognition at 1-5 years of

244 ve flow injection amperometric biosensor for organophosphate pesticides and nerve agents based on sel

245 a flow injection system was used to monitor organophosphate pesticides and nerve agents, such as par

246 em is an ideal tool for online monitoring of organophosphate pesticides and nerve agents.

247 ne associations between prenatal exposure to organophosphate pesticides and neurodevelopment.

248 Prenatal exposures to organophosphate pesticides and polychlorinated biphenyls

249 riculture and military activities, while non-organophosphate pesticides are mostly used in agricultur

250 Strong evidence now supports the notion that organophosphate pesticides damage the fetal brain and pr

251 In our cohort, exposure to organophosphate pesticides during pregnancy was not asso

252 ability of causation, in the European Union, organophosphate pesticides were the largest contributor

253 and three quaternary ammonium/three neutral organophosphate pesticides) were successfully analyzed w

254 Three organophosphate pesticides, chlorpyrifos, dichlorvos, an

255 were estimated for chemicals (methylmercury, organophosphate pesticides, lead) and a variety of medic

256 hree environmental chemicals (methylmercury, organophosphate pesticides, lead), the results suggest t

257 veloping high-performance sensors monitoring organophosphate pesticides, primarily due to their broad

258 ialkylphosphates, nonspecific metabolites of organophosphate pesticides, were measured.

259 Prenatal exposure to organophosphate pesticides, which is ubiquitous, may be

260 s on in-utero exposure to organochlorine and organophosphate pesticides.

261 viation increase in toxicity-weighted use of organophosphate pesticides.

262 polychlorinated biphenyls, organochlorines, organophosphates, phenols, metals, and other environment

263 e mechanism we propose may be a paradigm for organophosphate:phosphate antiporters.

264 capsule suspension formulations (CS) of the organophosphate pirimiphos methyl were evaluated as IRS

265 lopment of prophylactic therapeutics against organophosphate poisoning and other important targets.

266 Organophosphate poisoning can occur from exposure to agr

267 long-term toxic side effects associated with organophosphate poisoning.

268 f case reports, extrapolation from pediatric organophosphate poisonings, and expert opinion.

269 PON1 also hydrolyzes organophosphates, protecting the nervous system from tho

270 -II-1 populations of B. tabaci to the tested organophosphate, pyrethroid, and neonicotinoid insectici

271 el of the insecticide resistance to selected organophosphates, pyrethroids, and neonicotinoids in sev

272 tion with ever use of herbicides, fumigants, organophosphates, pyrethroids, or carbamates.

273 s reveal a strong association between plasma organophosphate residues and HbA1c but no association wi

274 Plasma organophosphate residues are positively correlated with

275 For the 11 organophosphates retained in the analysis, exposure (eve

276 aldoxime methiodide for reactivation of four organophosphate (sarin, cyclosarin, VX, and paraoxon) co

277 sterase activity from being inhibited by two organophosphate simulants.

278 Addition of an organophosphate source to UMR osteoblastic cultures acti

279 (DDFP)], a close analogue of the nerve agent organophosphate substrate diisopropyl fluorophosphate (D

280 The OPH activity for seven organophosphate substrates was simultaneously enhanced b

281 of these residues alter UhpT preference for organophosphate substrates.

282 ts, while being insensitive to inhibition by organophosphates such as paraoxon.

283 nas diminuta catalyzes the detoxification of organophosphates such as the widely utilized insecticide

284 Our findings extend earlier observations of organophosphate synergism in salmon and reveal an unusua

285 The organophosphate temephos a larvicide recommended by WHO

286 esterase (NTE), which is the target of toxic organophosphates that induce human paralysis due to seve

287 l as both biotherapeutics for treating acute organophosphate toxicity and as bioremediation agents.

288 ited arylesterase activity and resistance to organophosphate toxicity.

289 an high density lipoprotein (HDL)-associated organophosphate triesterase, suppresses atherosclerosis

290 Organophosphate triesters are high production volume add

291 inetic studies with a series of enantiomeric organophosphate triesters have shown that the wild type

292 world." However, synthesizing RNA and other organophosphates under plausible early Earth conditions

293 osphatases (APases) are important enzymes in organophosphate utilization in the ocean.

294 At least one of the organophosphates was detected in the analyzed samples at

295 The diabetogenic nature of organophosphates was recently reported but the underlyin

296 ates of exposure to pyrethroids and dimethyl organophosphates were higher in NYC than in the United S

297 Insecticides, particularly organophosphates, were the strongest modifiers of risk,

298 y occurs widely in synthetic pyrethroids and organophosphates, which are the mainstay of modern insec

299 diminuta (PdPTE), which hydrolyzes synthetic organophosphates with remarkable catalytic efficiency.

300 ngs suggest that impaction of the conjugated organophosphate within the constraints of the active cen