ライフサイエンスコーパス: organophosphorus

1 rate a double flagging method, where unknown organophosphorus acetylcholinesterase inhibitors are "fl

2 Organophosphorus acid anhydride (OP) "nerve agents" are

3 rate that this enzyme (but not a G117H/E197Q organophosphorus acid anhydride hydrolase catalytic vari

4 Organophosphorus acid anhydrolase (OPAA) was spontaneous

5 irst time, a nerve agent detoxifying enzyme, organophosphorus acid anhydrolase (OPAA), has been succe

6 t widely used reactions for the synthesis of organophosphorus acids, is presented.

7 can be used to search for new biomarkers of organophosphorus agent exposure.

8 go self-reactivation after inhibition by the organophosphorus agent paraoxon.

9 suitable for identifying exposure to unknown organophosphorus agents.

10 gh our exploration of the parameter space of organophosphorus agrochemical adsorption in zirconium-ba

11 rt the design of a general, redox-switchable organophosphorus alkyl radical trap that enables the syn

12 omplex pharmaceutical architectures to their organophosphorus analogs.

13 The material was applied for extraction of organophosphorus and carbamate pesticides prior to HPLC

14 lticlass pesticide residues (organochlorine, organophosphorus and synthetic pyrethroids) in edible oi

15 wo bacterial enzymes, phosphotriesterase and organophosphorus anhdrolase, are examined for their abil

16 tion (i.e. the fraction of P being buried as organophosphorus) are inversely correlated, suggesting t

17 The method employs a small-ring organophosphorus-based catalyst (1,2,2,3,4,4-hexamethylp

18 ethod operates by the action of a small ring organophosphorus-based catalyst (1,2,2,3,4,4-hexamethylp

19 inherent distinction in design criteria for organophosphorus-based catalysts operating via P(III)/P(

20 Terrorist use of organophosphorus-based nerve agents and toxic industrial

21 on the test line was able to recognize both organophosphorus BChE adducts (OP-BChE) and BChE and pro

22 This latter result confirms that the organophosphorus binding site of albumin is a tyrosine.

23 tic cleavage of the N-C and C-S bonds of the organophosphorus bridge leading to the formation of dime

24 ple and suggest additional opportunities for organophosphorus catalysis in a biphilic mode.

25 xhaustive deoxygenation of nitroarenes by an organophosphorus catalyst and a mild terminal reductant

26 ndem catalytic reaction cascade in which the organophosphorus catalyst drives two sequential and mech

27 An organophosphorus -catalyzed method for the direct electr

28 An organophosphorus-catalyzed C-N bond-forming reductive co

29 A method for electrophilic sulfenylation by organophosphorus-catalyzed deoxygenative O-atom transfer

30 An organophosphorus-catalyzed method for the synthesis of u

31 ect reductive N-arylation of nitromethane by organophosphorus-catalyzed reductive C-N coupling with a

32 atalytic bioscavenger countermeasure against organophosphorus chemical warfare agents and pesticides

33 Organophosphorus chemicals, including chemical warfare a

34 1)R(2)P(O)H are important functionalities in organophosphorus chemistry and display prototropic tauto

35 um ring synthesis, but were soon diverted to organophosphorus chemistry, and that eventually resulted

36 reaction has many potential applications in organophosphorus chemistry.

37 o different concentrations of the prototypic organophosphorus compound chlorpyrifos-oxon.

38 nic crystal sensing material that senses the organophosphorus compound parathion at ultratrace concen

39 on-magnetic nanomaterial functionalized with organophosphorus compound was used as solid-phase for ar

40 Iron nanoparticles modified with an organophosphorus compound were used as the solid phase f

41 lorimetry (ITC) to monitor the binding of an organophosphorus compound with the M-MFU-4l series to co

42 iron oxide nanoparticles with a bifunctional organophosphorus compound, N-(phosphonomethyl)iminodiace

43 -component mixture of a ketone, alcohol, and organophosphorus compound, the same level of ion isolati

44 detect the presence of paraoxon, which is an organophosphorus compound, using the layer-by-layer (LbL

45 selectively recognize small model molecules, organophosphorus compounds (OPCs), of high biological im

46 or the nontargeted identification of unknown organophosphorus compounds (OPCs).

47 Many organophosphorus compounds (OPs) are potent cholinestera

48 Organophosphorus compounds (OPs) being applied as flame

49 Organophosphorus compounds (OPs) continue to represent a

50 Exposure to organophosphorus compounds (OPs) may be fatal if untreat

51 volume) sensitivity to either organoamine or organophosphorus compounds are demonstrated, and their u

52 Organophosphorus compounds are fundamental building bloc

53 The pharmacology of weaponized organophosphorus compounds can be investigated using pho

54 A variety of substituted organophosphorus compounds can be obtained in one pot vi

55 Phosphonates are organophosphorus compounds characterized by a highly sta

56 se was found to be potently inhibited by the organophosphorus compounds chlorpyrifosmethyl oxon, dich

57 ent a detailed molecular characterization of organophosphorus compounds in ambient organic aerosol in

58 ck of detailed molecular characterization of organophosphorus compounds in BBOA is primarily due to t

59 Considering the ubiquity of organophosphorus compounds in organic synthesis, pharmac

60 Organophosphorus compounds include many synthetic, neuro

61 yme acetylcholinesterase (AChE), which binds organophosphorus compounds irreversibly, creating an ani

62 The one-pot synthesis of various important organophosphorus compounds is also demonstrated.

63 useful synthons for the preparation of other organophosphorus compounds is demonstrated.

64 ve protocol for the synthesis of aryl-methyl organophosphorus compounds is reported.

65 for the synthesis of biologically important organophosphorus compounds known as N-(alpha-phosphoryl)

66 Organophosphorus compounds represent a large class of mo

67 Biologically based extractions of organophosphorus compounds represent a new technique for

68 sing C, H, O, and P with or without N, i.e., organophosphorus compounds that have long been quantifie

69 A), but some of them like diclofenac and the organophosphorus compounds tri-o-tolyl phosphate and tri

70 ped an NMR method that selectively edits for organophosphorus compounds via (31)P-(1)H heteronuclear

71 A total of 52 brominated, chlorinated, and organophosphorus compounds were identified by suspect sc

72 l agent of meningitis, NmAPN) complexed with organophosphorus compounds were resolved to determine th

73 use such a system to detect the presence of organophosphorus compounds with speed and sensitivity us

74 y efficient catalytic scavenger of poisonous organophosphorus compounds, based on organophosphorus hy

75 the selective construction of various chiral organophosphorus compounds, catalytic enantioselective a

76 )R(2)P(S)OH constitute an important class of organophosphorus compounds, in which the phosphorus atom

77 ety of toxic acetylcholinesterase-inhibiting organophosphorus compounds, including fluorine-containin

78 Organophosphorus compounds, such as chemical warfare ner

79 on the reactivity of the fluoride ion toward organophosphorus compounds, we established that the extr

80 )O/(16)O ratio measurements in phosphate and organophosphorus compounds, which offers promising avenu

81 of aqueous fluoride ions to react with such organophosphorus compounds.

82 c metalloenzyme that hydrolyzes a variety of organophosphorus compounds.

83 preparation of H-phosphinic acids and other organophosphorus compounds.

84 r the cognitive-enhancing effects of certain organophosphorus compounds.

85 tion of a previously unrecognized target for organophosphorus compounds.

86 s is an atom-economical approach to valuable organophosphorus compounds.

87 rtunities to probe for (18)O/(16)O ratios in organophosphorus compounds.

88 s well recognized as a critical precursor to organophosphorus compounds.

89 omising candidates for the bioremediation of organophosphorus compounds.

90 N(R)C(=O)N(H)R], a new family of derivatized organophosphorus compounds.

91 on, and allows one-pot conversion to various organophosphorus compounds.

92 icient modification of phenyl substituent in organophosphorus compounds.

93 d choice of monomers and inhibitors, usually organophosphorus derivatives.

94 From target analysis, the organophosphorus ester flame retardants and plasticizers

95 Diisopropyl phosphorofluoridate (DFP) is an organophosphorus ester, which produces organophosphorus

96 is an organophosphorus ester, which produces organophosphorus ester-induced delayed neuropathy (OPIDN

97 isopropyl phosphorofluoridate (DFP) produces organophosphorus ester-induced delayed neurotoxicity (OP

98 Organophosphorus esters 9, 10, 14, and 15 prepared via r

99 .05) correlated with levels in blood plasma; organophosphorus esters in brooches and wristbands were

100 50 muL allow the production of 1.6-1.95 g of organophosphorus esters per hour.

101 ntibodies, serum cholinesterase (a marker of organophosphorus exposure), total and specific serum IgE

102 er and an organic phase containing an acidic organophosphorus extractant.

103 ylphosphate) (BPA-BDPP) are two halogen-free organophosphorus flame retardant (PFRs) that are used as

104 esorcinol bis(diphenylphosphate) (RDP) is an organophosphorus flame retardant widely used in electric

105 Heterodentate phosphines containing anionic organophosphorus groups remain virtually unexplored liga

106 Glyphosate is an organophosphorus herbicide that is applied to the leaves

107 e new wearable sensors, based on stretchable organophosphorus hydrolase (OPH) enzyme electrodes, are

108 needle sensor array relies on unmodified and organophosphorus hydrolase (OPH) enzyme-modified carbon

109 xins posing a threat to human life globally, organophosphorus hydrolase (OPH) has become the enzyme o

110 E. coli cells expressing organophosphorus hydrolase (OPH) on the cell surface wer

111 d layer of Escherichia coli cells expressing organophosphorus hydrolase (OPH) on the cell surface.

112 Organophosphorus hydrolase (OPH) was displayed and ancho

113 Structural changes in the enzyme organophosphorus hydrolase (OPH) were monitored upon ads

114 is study is to immobilize an enzyme, namely, organophosphorus hydrolase (OPH), and to detect the pres

115 n a biosensing scheme by integrating it with organophosphorus hydrolase (OPH), capable of selective O

116 s, mammalian serum paraoxonase and bacterial organophosphorus hydrolase (OPH).

117 isonous organophosphorus compounds, based on organophosphorus hydrolase (OPH, EC 3.1.8.1), is produce

118 Organophosphorus hydrolase (OPH, EC 8.1.3.1) is a dimeri

119 Organophosphorus hydrolase (OPH, EC 8.1.3.1) is a homodi

120 of rabbit serum paraoxonase, suggesting that organophosphorus hydrolase can hydrolyze phosphoryl oxim

121 of ligand recognition and the prolidase and organophosphorus hydrolase catalytic activities of OPAA.

122 h encapsulated seminapthofluorescein (SNAFL)-organophosphorus hydrolase enzyme conjugates.

123 hydrophobicity of CNT was used to immobilize organophosphorus hydrolase mutant with improved catalyti

124 Escherichia coli cells expressing the enzyme organophosphorus hydrolase on the cell surface and the o

125 ns of ClyA to the enzymes beta-lactamase and organophosphorus hydrolase resulted in synthetic OMVs th

126 Inclusion of the organophosphorus hydrolase signal sequence was necessary

127 Organophosphorus hydrolase was covalently immobilized on

128 ortant enzymes (PETase, cytochrome P450, and organophosphorus hydrolase).

129 rosinase and alkaline phosphatase or enzyme (organophosphorus hydrolase, OPH)) catalyzed reaction.

130 ered Escherichia coli with surface-expressed organophosphorus hydrolase.

131 first-row transition metal MOF catalysts for organophosphorus hydrolysis.

132 n, a discovery platform covering monodentate organophosphorus(III) ligands providing comprehensive ph

133 " out of a complex matrix by the presence of organophosphorus-indicative ions as well as their acetyl

134 Organophosphorus insecticide poisoning is not a single e

135 Each organophosphorus insecticide should be considered as an

136 omuscular dysfunction following ingestion of organophosphorus insecticides containing cyclohexanol pr

137 Although more than 100 organophosphorus insecticides exist, organophosphorus po

138 creased by exposure to dust-mite allergen or organophosphorus insecticides in urban and rural areas o

139 Intentional ingestion of agricultural organophosphorus insecticides is a significant public he

140 d to determine whether the three most common organophosphorus insecticides used for self-poisoning in

141 of these different types of pesticides (i.e. organophosphorus insecticides, phenoxy-acid herbicides,

142 ern--including some phenoxy acid herbicides, organophosphorus insecticides, polychlorinated biphenyls

143 anagement protocols developed for particular organophosphorus insecticides.

144 lowing intentional ingestion of agricultural organophosphorus insecticides.

145 o develop binary prophylactic agents against organophosphorus intoxication.

146 systematically explore the property space of organophosphorus ligands and how existing data sets in c

147 ion reactions promoted by catalysts based on organophosphorus ligands and iron.

148 sive development of iron complexes involving organophosphorus ligands applied in homogeneous catalyze

149 igand in [1H]BF(4) is readily substituted by organophosphorus ligands to afford the substituted deriv

150 marised for the main classes of extractants (organophosphorus ligands, diamides and N-heterocycles),

151 The detection and identification of organophosphorus molecules, particularly in the cases of

152 The planktonic synthesis of reduced organophosphorus molecules, such as alkylphosphonates an

153 (ddHRMS/MS) method capable of detecting all organophosphorus nerve agent (OPNA) adducts to human but

154 the binding and subsequent hydrolysis of an organophosphorus nerve agent simulant at Ti(IV)-based ac

155 The technique was characterized using the organophosphorus nerve agent VX.

156 l) methylphosphonothioate) is a highly toxic organophosphorus nerve agent, and even low levels of con

157 Hydrolysis of G- and V-series organophosphorus nerve agents (OPNAs) containing a phosp

158 (IMS) method for diagnosing exposure to the organophosphorus nerve agents (OPNAs) sarin (GB), cycloh

159 method for the simultaneous detection of the organophosphorus nerve agents (OPNAs) tabun (GA), sarin

160 ally cleaving, and thus detoxifying, several organophosphorus nerve agents and their simulants.

161 Recent events demonstrated that organophosphorus nerve agents are a serious threat for c

162 Organophosphorus nerve agents are among the most toxic c

163 ymes that efficiently hydrolyze highly toxic organophosphorus nerve agents could potentially be used

164 Organophosphorus nerve agents interfere with cholinergic

165 The organophosphorus nerve agents sarin, soman, tabun, and V

166 ich catalyzes the hydrolysis of a variety of organophosphorus nerve agents with high efficiency.

167 synthesized twelve fluorogenic analogues of organophosphorus nerve agents with the 3-chloro-7-oxy-4-

168 Organophosphorus nerve agents, a class of extremely toxi

169 protection against chemical warfare agents (organophosphorus nerve agents, blistering agents, and th

170 ate acetylcholinesterase (AChE) inhibited by organophosphorus nerve agents.

171 used as a medical countermeasure against the organophosphorus nerve agents.

172 meric, bacterial enzyme that detoxifies many organophosphorus neurotoxins by hydrolyzing a variety of

173 e detection of organophosphorus (OP) and non-organophosphorus (non-OP) pesticides.

174 Human albumin or plasma was treated with organophosphorus (OP) agent at alkaline pH, digested wit

175 e neonicotinoids acting as nAChR agonists or organophosphorus (OP) and methylcarbamate (MC) acetylcho

176 on electrode for discriminative detection of organophosphorus (OP) and non-organophosphorus (non-OP)

177 Organophosphorus (OP) compound poisoning is a major glob

178 Soman is an organophosphorus (OP) compound which irreversibly inhibi

179 Organophosphorus (OP) compounds are neurotoxins that are

180 Insecticide and nerve agent organophosphorus (OP) compounds are potent inhibitors of

181 Organophosphorus (OP) compounds cause toxic symptoms, in

182 gents soman, sarin, VX, and tabun are deadly organophosphorus (OP) compounds chemically related to OP

183 The possibility that organophosphorus (OP) compounds contribute to motor neur

184 Binding of certain organophosphorus (OP) compounds to NTE is believed to ca

185 es lactones, aromatic esters, and neurotoxic organophosphorus (OP) compounds, including insecticide m

186 sters, lactones, oxidized phospholipids, and organophosphorus (OP) compounds.

187 Organophosphorus (OP) insecticides and chemical warfare

188 Organophosphorus (OP) insecticides were the first group

189 Organophosphorus (OP) nerve agents are potent toxins tha

190 Organophosphorus (OP) nerve agents were used for chemica

191 been developed for vapor-phase detection of organophosphorus (OP) nerve agents.

192 tor erythrocytes for exposure of patients to organophosphorus (OP) pesticides and chemical warfare ag

193 phorylation for biomonitoring of exposure to organophosphorus (OP) pesticides and nerve agents based

194 Exposure to nerve agents or organophosphorus (OP) pesticides can have life-threateni

195 Organophosphorus (OP) pesticides have been used widely a

196 arget esterase (NTE) is inhibited by several organophosphorus (OP) pesticides, chemical warfare agent

197 Several chemicals, including organophosphorus (OP) pesticides, warfare agents and dru

198 One of the key acaricides is the organophosphorus (OP) proinsecticide coumaphos, that bec

199 As a consequence of organophosphorus (OP) toxins posing a threat to human li

200 Aging of organophosphorus (OP)-compound-inhibited neuropathy targ

201 O(2)@ZIF-8) to determine the residue of four organophosphorus (OPs) pesticides in cucumber samples.

202 significantly lower for pyrethroids than for organophosphorus or organochlorine insecticides, which s

203 as shown that the cumulative acute intake of organophosphorus or pyrethroid compounds from the consum

204 plant hormones, decreased residues of common organophosphorus, organochlorine and carbamate pesticide

205 harmaceutically relevant azaheterocycles via organophosphorus P(III)/P(V) redox catalysis is reported

206 An organophosphorus (P(III)/P(V) redox) catalyzed method fo

207 hobates pipiens) in 0, 1, or 10 mug/L of the organophosphorus pesticide chlorpyrifos (CPF) from hatch

208 elopment induced by in utero exposure to the organophosphorus pesticide chlorpyrifos that may account

209 time, we propose a biomimetic biosensor for organophosphorus pesticide detection employing a functio

210 Prenatal organophosphorus pesticide exposure and child neurodevel

211 n, and the substructure classes are standard organophosphorus pesticide groupings.

212 demonstrated a novel sensing strategy for an organophosphorus pesticide namely, malathion, employing

213 Chlorpyrifos is an organophosphorus pesticide used extensively in agricultu

214 thod to detect dimethoate (DMT), a hazardous organophosphorus pesticide, at concentrations below the

215 Fs/g-CN), as a catalyst for the detection of organophosphorus pesticide, parathion (PAT), for the fir

216 ChE biosensor enabled precision detection of organophosphorus pesticides (diazinon(oxon), chlorpyrifo

217 on, pre-concentration, and extraction of six organophosphorus pesticides (malathion, phosalone, dichl

218 their efficiency to extract eleven selected organophosphorus pesticides (OPPs) from apple juice samp

219 as a promising sorbent for the extraction of organophosphorus pesticides (OPPs) in juices, water, veg

220 TFME) method has been developed to determine organophosphorus pesticides (OPPs) in some fruits and ve

221 nt and its application for the extraction of organophosphorus pesticides (OPPs) in vegetable samples.

222 The adsorption properties toward organophosphorus pesticides (OPPs) were investigated.

223 ace solid-phase microextraction (HS-SPME) of organophosphorus pesticides (OPPs), diazinon (DIZ), and

224 proach for extracting and determining of two organophosphorus pesticides (OPPs), including diazinon a

225 raction for the selective enrichment of five organophosphorus pesticides (OPPs; diazinon, fenitrothio

226 trialization of food production, residues of organophosphorus pesticides (OPs) are more frequently fo

227 Organophosphorus pesticides (OPs) are used in agricultur

228 In view of the current serious situation of organophosphorus pesticides (OPs) residue contamination,

229 y of BChE could be irreversibly inhibited by organophosphorus pesticides (OPs), thus, the recovery ef

230 nd cotton farmers with long-term exposure to organophosphorus pesticides (OPs).

231 et for neurodegeneration induced by selected organophosphorus pesticides and chemical warfare agents.

232 resence of other chemical analogues, such as organophosphorus pesticides and herbicides, was investig

233 eric enzyme that catalyzes the hydrolysis of organophosphorus pesticides and nerve agents.

234 dict the toxicity or active substructures of organophosphorus pesticides and then are applied to scre

235 s amide, benzimidazole, methyl carbamate, or organophosphorus pesticides and with increasing numbers

236 rogel performance as a sensing platform, the organophosphorus pesticides edifenphos and parathion wer

237 d as a novel extractive device to extract of organophosphorus pesticides from fresh fruit juice sampl

238 y-mass spectrometry for the determination of organophosphorus pesticides in honey and fruit samples.

239 -tandem mass spectrometry to determine seven organophosphorus pesticides in rice samples.

240 Chemically analogous organophosphorus pesticides tested against the sensor ha

241 ng E. coli cells catalyzed the hydrolysis of organophosphorus pesticides to form stoichiometric amoun

242 chemical biosensor for the quantification of organophosphorus pesticides' level has been realized.

243 xtraction for selective determination of two organophosphorus pesticides, azamethiphos and chlorpyrif

244 analytes were seven specific metabolites of organophosphorus pesticides, five metabolites of synthet

245 mpaired by a variety of inhibitors including organophosphorus pesticides, leading to the accumulation

246 or the detection of acetylcholinesterase and organophosphorus pesticides.

247 outstanding selectivity factors of 4.45 for organophosphorus pesticides.

248 d the increased potency of oxygen analogs of organophosphorus pesticides.

249 ng methods to measure levels of the ollowing organophosphorus pesticides: chlorpyrifos, azinphos-meth

250 allylic bromides is catalyzed by a biphilic organophosphorus (phosphetane) catalyst.

251 rs played role in high mortality among acute organophosphorus poisoning (OP) poisoning patients inclu

252 h models for mild, moderate and severe acute organophosphorus poisoning by exposing zebrafish larvae

253 more effective countermeasures against acute organophosphorus poisoning is urgently needed.

254 han 100 organophosphorus insecticides exist, organophosphorus poisoning is usually regarded as a sing

255 ensive care unit (ICU) mortality among acute organophosphorus poisoning patients through a latent cla

256 r multifunctional drug therapy against acute organophosphorus poisoning.

257 Organophosphorus poisons (OP) bind covalently to the act

258 Overall, a variety of novel organophosphorus reagents and products were synthesized

259 n of bioavailable phosphate from immobilized organophosphorus represents a key process in the global

260 sting and goat milk farming leads to harmful organophosphorus residue accumulation, necessitating adv

261 thod could be useful for routine analysis of organophosphorus residue for monitoring purposes.

262 elines, for simultaneous determination of 10 organophosphorus residues in curry leaf using gas chroma

263 esign of highly evolved, genetically encoded organophosphorus scavengers and for broader functionalit

264 or producing novel supramolecular catalysts, organophosphorus scavengers, and nanostructured material

265 The neural network classification model for organophosphorus structural alerts achieved an Area Unde

266 valuated for two groups: aromatic amines and organophosphorus structural alerts.

267 etes by enabling the utilization of abundant organophosphorus substrates as C and P sources, providin

268 ble enzyme to hydrolyze such a wide range of organophosphorus substrates.

269 rated Lewis pairs consisting of tethered bis-organophosphorus superbases and a bulky organoaluminum t

270 thods to measure resistance to inhibition by organophosphorus toxicants (OP) for mutants of butyrylch

271 city from acute exposure to nerve agents and organophosphorus toxicants is due to irreversible inhibi

272 7 Ig-paraoxonase (WTIgP) as a reactibody for organophosphorus toxins.

273 Fluorinated organophosphorus(V) compounds are a very versatile class