ライフサイエンスコーパス: organozinc

1 of the binaphthyl polymers in the asymmetric organozinc addition has demonstrated that it is possible

2 dendrimers have been used for the asymmetric organozinc addition to aldehydes.

3 inyl-, and alkynylzinc additions and for the organozinc addition to ketones, although many good catal

4 Another much less explored area is the organozinc addition to ketones.

5 The exclusion of organozinc additives and base as well as the general syn

6 derived in situ from carboxylic acids) with organozinc and organomagnesium species using an Fe-based

7 valent of n-BuLi was added to form the mixed organozinc, ArZnBu.

8 Low-valent organozinc complexes can either be formed by ligand subs

9 [kappa(4)-Tptm]ZnF, the first example of an organozinc compound that features a terminal fluoride li

10 The obtained organozinc compounds can be easily functionalized with a

11 sponding Grignard reagents using ZnCl2 forms organozinc compounds which are functional group tolerant

12 addition, it has been found that one of the organozinc cyclizations does not occur in a system in wh

13 ombined findings strongly suggest that these organozinc cyclizations occur by a zinc radical transfer

14 coupling reaction of halogenated azines with organozinc derivatives of ferrocenes (the Negishi reacti

15 lic acid and economically replace it with an organozinc-derived olefin on a molar scale.

16 coupling of alkyl halides with pre-generated organozinc, Grignard and organoborane species has been u

17 ary allylic chlorides with readily available organozinc halides has been developed.

18 e S-acyl dithiocarbamates, which couple with organozincs in the presence of a copper(I) catalyst.

19 The resulting organozinc intermediates undergo facile allylation and a

20 romote ionization of the zinc-iodine bond in organozinc iodides under aqueous conditions, providing a

21 s (RXZnCH(2)Y) generated with an appropriate organozinc is very effective for the cyclopropanation of

22 An addition of organozinc nucleophiles to N-acyl activated quinolines a

23 ergo a second nickel-catalyzed reaction with organozincs or organoboranes to afford densely functiona

24 The reducing agents employed include organozincs, organoboranes, organosilanes, and methanol.

25 The reactivity of a representative set of 17 organozinc pivalates with 18 polyfunctional druglike ele

26 nvolved (i) the reaction of a glycal with an organozinc reagent (carrying an aryl iodide function) in

27 sp(3) C-C bonds from various styrenes and an organozinc reagent in a formal alkene hydroalkylation pr

28 Coupling of beta,beta-dichlorostyrene with organozinc reagent resulted in the formation of monocoup

29 epared using the Pd-catalyzed coupling of an organozinc reagent with the iodobenzothiazole 7 and subs

30 atalyzed carboxylation of the in situ formed organozinc reagent.

31 of a variety of organolithium, Grignard, and organozinc reagents (M-R) to 3-furfural provides 3-furyl

32 ing of acyl chlorides with gem-difluorinated organozinc reagents affording difluorinated ketones is d

33 ild Negishi cross-coupling of 2-heterocyclic organozinc reagents and aryl chlorides is described.

34 d gamma-selective allylic alkenylation using organozinc reagents are reported.

35 An efficient method to generate the organozinc reagents at room temperature is also demonstr

36 ce intermediates in the synthesis of soluble organozinc reagents by direct insertion of alkyl iodides

37 The functionalized organozinc reagents contain esters, silyl ethers, alkyl

38 onsistent with lithium chloride solubilizing organozinc reagents from the surface of the zinc after o

39 g reaction between N-sulfonyl aziridines and organozinc reagents is reported.

40 proach toward the generation of Grignard and organozinc reagents mediated by a titanocene catalyst.

41 irected carbozincation of cyclopropenes with organozinc reagents prepared by I/Mg/Zn exchange.

42 A variety of N-chloroamines as well as organozinc reagents react smoothly under the reaction co

43 ethod is broadened by the ability to utilize organozinc reagents that have been generated in situ fro

44 ds in highly diastereoselective additions of organozinc reagents to a variety of alpha-chloro aldimin

45 iles such as allylsilanes, silyl ethers, and organozinc reagents to afford diverse alpha-morpholinoam

46 a BF3.OEt2-mediated addition of Grignard or organozinc reagents to pyridines bearing various substit

47 y available racemic alpha-haloboronates with organozinc reagents under mild conditions.

48 The reaction involves interaction of organozinc reagents with (bromodifluoromethyl)trimethyls

49 ystem for the Pd-catalyzed cross-coupling of organozinc reagents with aryl halides (Negishi coupling)

50 unctions direct the addition of a variety of organozinc reagents with excellent facial selectivity.

51 The compatibility of organozinc reagents with other functional groups makes t

52 tuted-pyrrolidin-2-ones 9 with allylsilanes, organozinc reagents, and phosphorus compounds.

53 A method for the coupling of organozinc reagents, difluorocarbene, and allylic electr

54 -, aspartic acid-, and glutamic acid-derived organozinc reagents, followed by cross-metathesis of the

55 With the high functional group tolerance of organozinc reagents, the mild Lewis acidity of RZnX, and

56 halogenated and/or asymmetrical systems, and organozinc reagents.

57 f aliphatic N-tosylaziridines with aliphatic organozinc reagents.

58 reaction between simple alkyl aziridines and organozinc reagents.

59 ant (TDAE) argue against the intermediacy of organozinc reagents.

60 table partners for asymmetric couplings with organozinc reagents.

61 hi-like cross-coupling of alkyl halides with organozinc reagents.

62 or acyl halides with aliphatic and aromatic organozinc reagents.

63 d by two methods involving cross-coupling of organozinc reagents.

64 The diastereoselective addition of organozinc species to 1,2-anhydro sugars in toluene/n-di

65 ane followed by nitrosation of difluorinated organozinc species with an n-butyl nitrite/chlorotrimeth

66 d methods (e.g., Suzuki organoboron, Negishi organozinc, Stille organotin, Kumada organomagnesium, et

67 and employed as catalysts in the addition of organozincs to benzaldehyde.