ライフサイエンスコーパス: origin

1 n the genome, termed origins of replication (origins).

2 observed on beta-cell mass have an embryonic origin.

3 6.4 per mil, consistent with a soil biogenic origin.

4 face markers compatible with a marginal zone origin.

5 ent in cocoa beans depending on genotype and origin.

6 ify which, among these modes, have a pure HB-origin.

7 gs compared with GC of a more differentiated origin.

8 (9,414 with breast cancer), all of European origin.

9 der pathways is crucial to understanding its origin.

10 ockade, regardless of the cancers' tissue of origin.

11 f melanoma and small cell lung cancer (SCLC) origin.

12 n of analyzed samples regarding the fruit of origin.

13 logical evolution of cells leading to life's origin.

14 variety of antibody sequence and species of origin.

15 hat elevated CRE and blaNDM-1 are of patient origin.

16 ce that regional differences were of genetic origin.

17 entromeric sites adjacent to the replication origin.

18 ral organs is heterogeneous with a myopathic origin.

19 e the most abundant classes of anthropogenic origin.

20 infection was frequent and multifactorial in origin.

21 bserved, of which 207 were of cardiovascular origin.

22 ofibroblasts are largely determined by their origin.

23 larger ensembles generated in the species of origin.

24 sent from living collections are tropical in origin.

25 nds in wine issued from multiple and complex origins.

26 haplotypes had Asian, African, and European origins.

27 n foundational in investigating agricultural origins.

28 etal-bearing PM2.5 had predominantly outdoor origins.

29 ed for other samples of different geographic origins.

30 regulating interactions between pericentric origins.

31 sting that inequalities in health have early origins.

32 to slower synthesis rates and closer-spaced origins.

33 ting idiolectal features with likely African origins.

34 s stemming from bacterial, fungal, and viral origins.

35 by suppressing the firing of new replication origins.

36 igmatism in complicated cases with different origins.

37 ations for our view of modern chondrichthyan origins, add robust structure to the phylogeny of early

38 ) helicase complexes at many DNA replication origins, an essential process termed origin licensing.

39 British, German Italian, Spanish and Swedish origin and 1,354 ethnically matched controls and from 92

40 ary extracellular vesicles (EVs) of podocyte origin and accompanied by increased urinary soluble neph

41 we use whole-genome sequences to examine the origin and adaptation of the two major strains of weedy

42 s of sRNAs, which are distinguished by their origin and biogenesis, exist in plants.

43 The origin and cellular complexity of eukaryotes represent a

44 s was proposed in several species, yet their origin and characteristics are not very clear.

45 However, due to their ancient origin and complex diversity, many tectiviral proteins a

46 view recent evidence that sheds light on the origin and developmental unfolding of the link between l

47 ntingtin/EF3/PP2A/Tor1) repeat domains whose origin and distribution have not yet been characterized.

48 Yet, the origin and early history of therians and their close rel

49 hat may reveal important clues regarding the origin and epidemiology of the disorder as well as the p

50 The origin and expansion of biological diversity is regulate

51 an exceptional tracer for investigating the origin and fate of volatile elements on Earth.

52 the adult CNS, providing insights into their origin and functional diversity.SIGNIFICANCE STATEMENT W

53 We aimed to elucidate the origin and hydrological pathways of BTs in Toronto, Cana

54 In this review we discuss the origin and influence of microbiome-modulated metabolites

55 We demonstrate that the locations of origin and introduction of alien birds, and their identi

56 Depending on their origin and level of differentiation at which they are ha

57 ustness, but the mechanisms underlying their origin and maintenance remain disputed.

58 In this study, we investigated their origin and mechanism of recruitment.

59 e of the deadliest cancers, yet the cells of origin and mechanisms of tumor initiation remain unclear

60 tion and morphology, but their developmental origin and mode of homeostatic maintenance are unknown.

61 ty of infarct fibroblasts were of epicardial origin and not derived from bone marrow lineages, endoth

62 rate current knowledge regarding the natural origin and occurrence of industrially important organoha

63 roviruses as a whole, have an ancient marine origin and originated together with, if not before, thei

64 nt nucleic acid polymerase families, (b) the origin and phylogenetic distribution of TBP, TFB, and TF

65 few surviving textual records and thus their origin and relationship to ancient and present-day popul

66 This natural dye is of insect origin and should not be present in Kosher and Halal foo

67 The origin and significance of these profiles remain largely

68 r identification of the epiphyseal cartilage origin and subsequent stages of ossification in JOCD.

69 Botanical origins and chemical compositions including sugars were

70 The disparate biosynthetic origins and distant phylogenetic distribution implies th

71 tively little attention has been paid to the origins and history of wild rice itself.

72 T530-pSIRT1 associates with replication origins and inhibits replication from a group of 'dorman

73 pport the unique, dual model for insect wing origins and the convergent reduction of notal fusion in

74 Here, we characterize origins and transformations of dissolved organic matter

75 ave distinct selectivity (feature vs. eye of origin) and dynamics (relatively slow vs. relatively fas

76 colorectal adenoma and CRC are monoclonal in origin, and the CRCs further diversified into different

77 tically assess the nomenclature, prevalence, origins, and effect on treatment adherence of TCS phobia

78 Salvadoran origin (aOR = 6.2; 95% CI = 2.8-13.5; P < .001), prior k

79 showing that organic molecules of biological origin are incorporated in LSA from HABs.

80 influenza (HPAI) viruses, but such viruses' origins are often unclear.

81 We show that origins are very closely spaced in Plasmodium compared t

82 rary on a panel of cancer cells of different origins as well as normal cells.

83 uction in DLBCL was unrelated to the cell of origin, as APRIL-producing neutrophils infiltrated CXCL-

84 imited use in unravelling their evolutionary origin, as the earliest recognized examples already exhi

85 olution in water to protein folding, but its origin at the fundamental level is still unclear.

86 73 families) with BMF of suspected inherited origin but unresolved diagnosis after medical evaluation

87 ong with this study, share the same physical origins but with differing physical boundary conditions.

88 numerous, not because Mexico is a center of origin, but because of high rates of lineage diversifica

89 nt human cancer cell lines of diverse tissue origin by blockade of nuclear FOXO4 degradation and indu

90 Their origin cannot be understood by a morphological compariso

91 scriminated between inflammations of various origins (colitis from arthritis).

92 Here, we purified and assessed the origin, concentration and content of circulating MPs fro

93 arate regions of similarly timed replication origins connecting the long-known effect of genomic cont

94 ic impact and interdependence of the cell-of-origin (COO) classification, dual expression (DE) of MYC

95 chromatin during DNA replication: promoting origin dependence and determining Okazaki fragment lengt

96 after adjusting for maternal age, country of origin, educational level, cohabitation with a partner,

97 ariants and genes along with their taxonomic origins enables novel strains to be characterized.

98 lutionary studies aimed at understanding the origin, evolution, and ecology of the exceptional biodiv

99 Storms from different dust origins exhibited distinct bacterial communities, with s

100 Replication stress and deregulated origin firing increase the number of HO collisions leadi

101 ation stress checkpoint, promoting continued origin firing.

102 Interestingly, either origin-flanking nucleosomes or roadblocks resulted in he

103 bility depended most on biospecimen type and origin, followed by DNA extraction, sample handling envi

104 dulthood, we investigated a common pituitary origin for hypothyroidism and macroorchidism, and the ro

105 erial genomes are consistent with an ancient origin for M. elongata - M. cysteinexigens symbiosis, mo

106 ty zones validate a compositionally distinct origin for most ultralow velocity zones.Ultralow velocit

107 romyographic studies demonstrated a cortical origin for myoclonus and striking coactivation of agonis

108 ated with a shift to drought in the areas of origin for the Cimbri, Quadi, Visigoths, Ostrogoths, Hun

109 Together, our analyses point to a complex origin for the sex chromosome of C. gomesi and highlight

110 of the NAO caused drought in the regions of origin for tribes in antiquity, and may have created a p

111 We show a topological origin for two well-known equatorially trapped waves, th

112 -analysis of samples with Asian and European origins for five SNPs in CHRNB3 showed significant assoc

113 n is blocked by stigmatellin, indicating its origin from complex III, and by piericidin, demonstratin

114 eir main protein component, indicating their origin from low-density lipoprotein, intermediate-densit

115 of 277 RT017 isolates from animal and human origins from six continents, isolated between 1990 and 2

116 In contrast, ATR-Chk1 inhibitor-induced origins generate additional replication forks that are t

117 rn China], urbanity [urban vs rural], ethnic origin [Han and non-Han], occupation [farmer and non-far

118 Each new origin has evolved a new mycangium.

119 d thermal structure of our planet, but their origin has long been debated.

120 in DIPG provides insights toward the cell of origin, highlighting oligodendroglial lineage genes, and

121 This is thought to have evolutionary origins, highlighting objects likely to provide benefit

122 Much of this difference may be dietary in origin; however, this is not well established.

123 quired during long-term circulation of avian-origin IAVs in mammals.IMPORTANCE Canine influenza is a

124 tion may reflect differences in geographical origin.IMPORTANCE New DNA sequencing technologies have m

125 olves as the primary tumor migrates from its origin in the pancreas to colonize distant metastatic si

126 or demise, can contain a barcode of the cell origin, including specific microRNAs (miRNAs).

127 d with climate factors at accession sites of origin, indicating its potential involvement in drought

128 ed that cardiac RNA of both human and rodent origins induced cytokine production and immune cell acti

129 Here we show that developmental origins influence fine-scale synapse formation and micro

130 rus, we sequenced and analyzed 441 wild-bird origin influenza virus strains isolated from wild birds

131 methylated-CpGs, consistent with ORCA-bound origins initiating DNA replication late in S-phase.

132 ected on the core-mantle boundary, but their origin is enigmatic.

133 ication origins, an essential process termed origin licensing.

134 ative estimation of tumor load and tissue-of-origin mapping in the circulating cell-free DNA of 59 pa

135 iously used as models to understand dinosaur origins may represent specialized forms rather than the

136 we infer that Spanish teosinte is of admixed origin, most likely involving Zea mays ssp. mexicana as

137 ty acids with disease risk, therefore, their origin needs to be determined to understanding their rol

138 mmunities in dust storms from three distinct origins (North Africa, Syria and Saudi Arabia) and compa

139 odern specimens, we determine the biological origin of 15 Viking Age (800-1066 CE) and subsequent med

140 uated evolutionary hypotheses concerning the origin of a recently recognized decaploid strawberry (Fr

141 Here we investigated the origin of activated myofibroblasts and the molecular mec

142 p of the hematopoietic hierarchy and are the origin of all blood cells produced throughout an individ

143 Our findings elucidated the common origin of all CS-PPR converter genes except CBL-CIPK con

144 The cellular origin of alpha-synuclein in GCI and a 'prion hypothesis

145 assic sediments, which predates the accepted origin of angiosperms, suggests that microbial sources o

146 es could be used in tracing the geographical origin of animal produce and tissues, and there is a pos

147 votal role in the attempts to understand the origin of biological complexity by exploiting the power

148 pathologic heterogeneity is due to a cell of origin of bipotent liver progenitors or the plasticity o

149 ch as chronic fetal hypoxia, trigger a fetal origin of cardiovascular dysfunction and programme cardi

150 These results implicate a monocytic origin of CD11c(+) cells in inflamed islets and suggest

151 zation of Vimentin confirmed the mesenchymal origin of cells and tracked morphological changes during

152 To further examine the origin of changes in intracortical inhibition we assesse

153 The origin of cometary matter and the potential contribution

154 e and organoboron reactivity issues, and the origin of competing oxidation/protodeboronation side rea

155 pregnancies support a predominantly maternal origin of effect.

156 ed by a ramp/flat fault was suggested as its origin of formation; however, this is inconsistent with

157 ORM/eQTL gain new discoveries on the genetic origin of gene expression differentiation in Caenorhabdi

158 providing a framework for understanding the origin of global selection pressures on proteins.

159 the final statistical discrimination of the origin of hams.

160 The tumour-specific origin of HBB is confirmed by sequence polymorphisms wit

161 By identifying the cellular origin of high affinity IgE and the clonal selection of

162 We aimed to trace the geographic origin of HIV-1 infection for migrants who inject drugs

163 Fossil evidence points to an African origin of Homo sapiens from a group called either H. hei

164 as well as accurately inferring the spatial origin of individuals on a two-dimensional continuum.

165 color lexicons, and the potential biological origin of infant color categories.

166 The results may help in understanding the origin of interface instabilities and the resulting non-

167 roduction and propagule pressure) and to the origin of introduced species (wild-caught species show h

168 However, the origin of its immunological activity is still unknown.

169 may provide a compelling description of the origin of large Hesperian-aged layered sulfate deposits

170 sed on the investigation, we reveal that the origin of leakage current in NbOx is partly due to insuf

171 e Earth's surface, and is central to current origin of life hypotheses as well as the search for micr

172 has become a key unanswered question in the origin of life.

173 We review hypotheses of the cell of origin of liver tumorigenesis and clarify the classes of

174 The temporal origin of Madagascar's extraordinary endemic diversity i

175 e mimetic dsx haplotype that occurred at the origin of mimicry.

176 was lost 300 million years ago, before the origin of modern beetles.

177 re fundamentally linked by the developmental origin of multiple GU tissues, including the kidneys, go

178 the hypothesis that the natural and ancient origin of organohalogens could have primed development o

179 Instead, major innovations - from the origin of oxygenic photosynthesis, to the evolution of r

180 res, branching vascular networks (BVNs), and origin of PCV using optical coherence tomography angiogr

181 We show that the origin of Pgt isolates virulent on Sr35 is associated wi

182 n cyclostomes and gnathostomes, and a single origin of pharyngeal gills prior to the divergence of th

183 women (n = 10), intragastric DB switched the origin of phase III contractions from the stomach to the

184 The origin of PHE is the peculiar time-reversal-breaking eff

185 This in turn diminished the embryonic origin of postnatal NSCs, resulting in loss of adult NSC

186 Homochirality is explained by origin of prebiotic life in one hemisphere of earth and

187 le tail hair in determining the geographical origin of raw cow milk in Peninsular Malaysia had been i

188 Very little is known about the ancient origin of retroviruses, but owing to the discovery of th

189 dress intriguing question about the place of origin of Russian Starovers, an enigmatic Eastern Orthod

190 ociated with the vagina indicated the likely origin of some peptidergic fibers.

191 cepts of single cell-SERS analysis including origin of spectral bands and experimental parameters for

192 re employed to investigate the mechanism and origin of stereoinduction in asymmetric iron-catalyzed C

193 arch into the attractors' basins reveals the origin of stochasticity, hysteresis and multistability i

194 The origin of super-massive black holes in the early univers

195 ferent approaches to analysing the botanical origin of tannins have been proposed in the last fifteen

196 approximately 80 million years, close to the origin of termite eusociality.

197 We suggest that the origin of the abnormal composition change is the differe

198 esigned for the ORR or the OER; however, the origin of the advanced activity of oxygen electrocatalys

199 Experimental studies on the origin of the backward oxidation peak of MOR coincide we

200 ncreased risk for fracture, yet the cellular origin of the bone phenotype remains unknown.

201 technique ((18)O and (2)H) to determine the origin of the C2(1)-formyl group of Chl f and to verify

202 ne)mO], in order to elucidate the electronic origin of the curious "kinked'" spine geometries that ar

203 However, usually neither the origin of the driving force nor the underlying pathways

204 ted reaction mechanisms and to elucidate the origin of the electrophilic reactivities.

205 ister" hypothesis), consistent with a single origin of the gut, nerve cells, and muscle cells in the

206 er monitoring is encouraged to elucidate the origin of the highest (240)Pu/(239)Pu atom ratio of 0.29

207 CHx radicals whose polymerization is at the origin of the IOM.

208 electron transfer in the solid state and the origin of the long-lived charge-separated state were stu

209 ons are the underlying driving force for the origin of the observed helicity in perfluoroalkanes.

210 We propose a new approach to understand the origin of the pseudogap in the cuprates, in terms of bos

211 The nature and origin of the signal is still not understood, but it has

212 The origin of the symmetric anticlines, which have bends on

213 anelles has led to uncertainty regarding the origin of the viral membrane.

214 Furthermore, the origin of these cells from myelin and Remak cells and th

215 Although the origin of these compounds is still unknown, we present e

216 talogue of TSC serves as a resource into the origin of these hamartomas and provides a framework that

217 Further evidence suggests a thymic origin of these mutant ILC2s.

218 res in DPED and determined the frequency and origin of these OCT signatures in a clinical cohort of D

219 ter morphology and size of particles but the origin of this dependence is largely due to the scatteri

220 ght-dependent or -independent; the molecular origin of this difference is unknown.

221 First, we describe the origin of this framework and its evolution over time.

222 The physiological origin of this pain (critical to its treatment) remains

223 The origin of this periodicity is rooted in the symmetry pre

224 chiral imprinting of the dots may lie at the origin of this phenomenon.

225 ractions than the earlier actinides, yet the origin of this shift in chemistry is not understood.

226 notype of domesticated barley shows that the origin of this trait is more complex than previously tho

227 To determine the origin of this virus, we sequenced and analyzed 441 wild

228 ers that can both load simultaneously on the origin of transfer DNA.

229 ded as nonskeletogenic, and so the embryonic origin of trunk denticle odontoblasts remains unresolved

230 Understanding the origin of unintentional doping in Ga2O3 is key to increa

231 ts high clinical relevance, the evolutionary origin of USA300 remained unclear.

232 metal-insulator phase transition (MIT), the origin of which is still under debate.

233 ive stress that could be monitored for early origins of adult chronic diseases.

234 to have been an important constraint on the origins of agriculture.

235 with children showing a dissociation in the origins of and developmental change seen in these two se

236 and Allergy Study [n = 30] and the Childhood Origins of Asthma Study [n = 28]) was analyzed by using

237 Children enrolled in the Childhood Origins of ASThma study were followed prospectively from

238 ly translatable therapy for preventing fetal origins of cardiovascular disease in pregnancy complicat

239 hese results extend our understanding of the origins of cooperativity and stability in protein foldin

240 Clarification of the origins of coronary endothelial cells during cardiac rep

241 roperties of tissue has helped to reveal the origins of disease; however, cellular-scale resolution i

242 ally important precursor in the evolutionary origins of group living in the squamates.

243 en a focus of research since Darwin, but the origins of humans' economical walking gait and endurance

244 otein mimetics and provides insight into the origins of ice-growth inhibition.

245 sis of 2007-2008, a deep analogy between the origins of instability in financial systems and complex

246 natural thermosensor protein, the molecular origins of its unfolding complexity, highlights the role

247 discipline that sought explanations for the origins of life from chemical and physical first princip

248 s shed light on the epigenetics and cellular origins of lineage-specific lung tumours.

249 icroscopy at various locations to reveal the origins of microstructural variability in this sensory m

250 up an important discussion on the nature and origins of numerosity perception.

251 hey carry multiple proteins that reflect the origins of parent cells.

252 tudies and for elucidating the developmental origins of pediatric neoplasms.

253 While the origins of physiological tremor are known to depend on m

254 , much less is known about the developmental origins of pigment cells produced in adult organisms dur

255 model was built to represent the structural origins of regio- and enantioselectivity.

256 ultiple discrete sites in the genome, termed origins of replication (origins).

257 rime target in the search for the regulatory origins of T cell dysfunction in chronic viral infection

258 The evolutionary origins of the hypoxia-sensitive cells that trigger amni

259 ze dictates the debris volume, revealing the origins of the long-standing hypothesized correlation be

260 e energetic significance and physicochemical origins of this class of sigma-hole interaction.

261 Understanding the physical origins of this low efficiency can provide strategies to

262 A farther search for origins of this phenomenon showed that the type of cryst

263 sis is a useful cnidarian model to study the origins of TLR signaling because its genome encodes a si

264 ed on recombination proteins and replication origin (oriC) degradation.

265 controlling for HIV status and continent of origin, people from Africa had a higher risk for dual-st

266 and treating cognitive disorders of various origins, preferably in patients with unsatisfactory resp

267 ir own mother's milk and avoidance of bovine-origin products might reduce the risk of necrotising ent

268 e to cluster samples according to patient-of-origin rather than region-of-origin within the multi-reg

269 directly after replication both chromosomal origin regions localize to the future cell division site

270 as focal neurological symptoms of ischaemic origin resolving spontaneously.

271 e H3N8 and H3N2 viruses, of equine and avian origins, respectively.

272 ase loading being dependent on an additional origin sequence known to be a weaker ORC-DNA-binding sit

273 ommon in many human cancers but of uncertain origin, served as an intermediary step in MV reversion t

274 lastoma, an embryonal cancer of neural crest origin, shows metastases frequently at diagnosis.

275 sorders traditionally considered of cerebral origin.SIGNIFICANCE STATEMENT This study examines the bi

276 despite the ubiquity of this phenomenon its origin still remains a subject of debate.

277 -67, BrdU), pallial/subpallial developmental origin (Tbr1, Sp8), and neuronal/glial antigens for phen

278 We combine a 97-amino-acid peptide of human origin that binds hyaluronan, a major macromolecular com

279 ial renewal occurs, but the specific cell of origin that supports this high proliferative demand rema

280 f the ORCA-bound sites represent replication origins that also associate with the repressive chromati

281 r of chemical products coming from different origins that can contaminate water and become toxicants

282 re, we report that Dbf4 is enriched at early origins through its interaction with forkhead transcript

283 aster synthesis rates and more widely-spaced origins through to slower synthesis rates and closer-spa

284 ion factors yet are defective in replication origin timing control.

285 gene expression with a chromosomal bias from origin to terminus, which is associated with a similar g

286 activation reduced the cytotoxicity of human-origin type 1 diabetes-relevant autoreactive CD8(+) T ce

287 The neural origins underpinning these changes remain unclear, altho

288 However, MPs from leukocytes and monocytes origin were increased in CF patients.

289 m these tumors showed that cells of NSC-like origin were more tumorigenic, had a higher rate of self-

290 Samples from different origins were analysed by UV-vis according to ISO 3632 (2

291 ses with attention to the cancer's tissue of origin, which revealed tissue-specific differences in se

292 m a group of 'dormant' potential replication origins, which initiate replication only when cells are

293 ressive chromatin environment at a subset of origins, which primes them for late replication.

294 For cells of myeloid origin, while integrins function at the level of adhesio

295 ntify patients with a CI defect of Mendelian origins, whilst highlighting the necessity of complete m

296 3684 female individuals) and shared genetic origin with conduct problems in a population-based sampl

297 ated ALK- cell lines of various histological origins with JAK inhibitors.

298 nyl)-2H-chromene-6-carboxylate of polyketide origin, with activity against human opportunistic food p

299 ules are associated with their developmental origin, with regions derived from the anterior mandibula

300 g to patient-of-origin rather than region-of-origin within the multi-region dataset.

301 A reproducible neuronal model of human origin would facilitate studies of HSV and other neurotr