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1 has become a key unanswered question in the origin of life.
2 entory with left-handed molecules before the origin of life.
3 believed to have been a key event during the origin of life.
4 grated behaviors was a crucial aspect of the origin of life.
5 tifying in its implications for the chemical origin of life.
6 e patterns, we attempt to glance at the very origin of life.
7 ts, where they may have played a role in the origin of life.
8 d to the organic inventory necessary for the origin of life.
9 tions for organic chemical evolution and the origin of life.
10 and thus possibly played a vital role in the origin of life.
11 catalysts available at an early stage in the origin of life.
12 two hydrophobic faces, was essential to the origin of life.
13 unlikely that cytosine played a role in the origin of life.
14 an RNA-like substance, played a role in the origin of life.
15 for this enzyme in the proposed autotrophic origin of life.
16 ating peptides may have played a role in the origin of life.
17 biomedical utility and implications for the origin of life.
18 0(6) yr) to be involved in a low-temperature origin of life.
19 and are thought to have been crucial for the origin of life.
20 n the origin of metabolism, and probably the origin of life.
21 nce on organic chemical evolution before the origin of life.
22 ave been a critical process required for the origin of life.
23 able C1 feedstock molecule is crucial to the origin of life.
24 mperature gradients might play a role in the origin of life.
25 isms that must have been available since the origin of life.
26 and have been implicated in theories of the origin of life.
27 communities and their potential role in the origin of life.
28 ns a mystery in the puzzle to understand the origin of life.
29 cation is considered a key transition in the origin of life.
30 ctions, and possibly virus evolution and the origin of life.
31 ng been sought by chemists interested in the origin of life.
32 lusion with significant implications for the origin of life.
33 onucleic acid (RNA) at an early stage in the origin of life.
34 to be involved in chemical evolution and the origin of life.
35 idy, genomic complexity, speciation, and the origin of life.
36 tion with their possible contribution to the origin of life.
37 plets is considered an essential step in the origin of life.
38 ng the possible pathways responsible for the origin of life.
39 for nonenzymatic RNA replication during the origin of life.
40 of potential relevance to understanding the origin of life.
41 and would seem to be a prerequisite for the origin of life.
42 mond Bernal proposed a role for clays in the origin of life.
43 ally with population density since the early origins of life.
44 possible progenitor candidates of RNA in the origins of life.
45 create novel proteins and to understand the origins of life.
46 n evolutionary development as ancient as the origins of life.
47 have made a significant contribution to the origins of life.
48 aqueous conditions is a critical step in the origins of life.
49 ate problem in the "RNA first" model for the origins of life.
50 igomers that would have played a role in the origins of life.
51 biosphere, and may have implications for the origins of life.
52 tion have the potential to shed light on the origins of life.
53 nvestigate various scenarios relevant to the origins of life.
54 arly relevant to prebiotic chemistry and the origins of life.
55 solutions to many basic questions about the origins of life.
58 and polypeptides was a key transition in the origin of life and remains at the heart of all biology.
59 The finding provides insights into both the origin of life and the potential threat posed by pathoge
60 kely to have played an important role in the origin of life, and a small number of fully synthetic se
61 e compartments is a central question for the origin of life, and has technological repercussions in d
62 forces will have been omnipresent since the origin of life, and living organisms have evolved mechan
63 role in hydrothermal redox chemistry at the origin of life, and materials applications that utilize
66 A) have been invoked as key reagents for the origin of life as activated forms of acetate analogous t
68 cal evidence for the physical setting of the origin of life because there are no unmetamorphosed rock
69 thought to be an unlikely mechanism for the origins of life because of unfavourable chemical conditi
70 es support for the involvement of RNA in the origin of life, but such support would be considerably s
71 s pioneered modern research on the molecular origins of life, but their actual relevance in this fiel
72 uch forces may have been instrumental in the origin of life by driving a primitive form of self-repli
73 urrent experiments with implications for the origin of life, emphasizing the ability of unexpected ph
76 nt a current view of the biochemistry of the origin of life, focusing on issues surrounding the emerg
77 arth's water is central to understanding the origins of life-fostering environments and to assessing
78 discipline that sought explanations for the origins of life from chemical and physical first princip
79 rebiotic organic molecules important for the origins of life from impacts of carbonaceous asteroids a
82 nt synthetic approaches to understanding the origin of life have yielded insights into plausible path
83 e Earth's surface, and is central to current origin of life hypotheses as well as the search for micr
84 step in quantifying and thus testing various origin-of-life hypotheses regarding the origin and evolu
85 ation flowed symmetrically in the era of the origin of life, i.e. the primitive translation machinery
86 e reaction conditions are compatible with an origin of life in volcanic-hydrothermal sub-seafloor flo
88 is profoundly contingent in that independent origins of life in the universe will spawn radically dif
90 e components have properties relevant to the origin of life, including the ability to self-assemble i
91 s in particular transformed the study of the origin of life into a respectable field of inquiry and e
93 nt obstacle to the "RNA-first" model for the origin of life is an inability to generate reasonable "h
94 The concept of an RNA world in the chemical origin of life is appealing, as nucleic acids are capabl
100 rsal chart of pathways may be central to the origin of life, is emergent from organic chemistry, and
104 100 yr), we conclude that a high-temperature origin of life may be possible, but it cannot involve ad
110 across a membrane was a critical step at the origin of life on earth, and it is still performed in al
111 ch are believed to have been critical to the origin of life on Earth, remain important in physiology
123 as RNA is considered a key transition in the origin of life, pre-dating the appearance of protein enz
124 is thought to have played a key role in the origin of life prior to the evolution of ribozyme-cataly
125 made on parameter estimation for determining origins of life probabilities, based on constraints from
132 ch as this will be increasingly necessary as origins-of-life researchers move toward systems-level in
133 rding to a current "RNA first" model for the origin of life, RNA emerged in some form on early Earth
134 ose the concept of a ribofilm in which RNA's origin-of-life role is more akin to a slowly changing pl
138 will be close to a full understanding of the origin of life, so the future of research in this field
146 hetic drugs to biodegradable plastics to the origin of life, the chiral selection of molecules presen
147 cs of chemical reactions associated with the origin of life, the energetics of early metabolisms, and
148 ortance of molecular self-replication in the origin of life, the feasibility of peptide self-replicat
150 an say nothing about the temperatures of the origin of life, the RNA world, and organisms preceding t
152 tion encoded in their genomes, and since the origin of life this information has been encoded using a
155 emergence of functional sequences during the origin of life would be possible even in the face of the
156 chemical homochirality was a key step in the origin of life, yet prebiotic mechanisms for chiral sepa
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