ライフサイエンスコーパス: originally

1 phenotype are more complex than anticipated originally.

2 g, fluorophore-loaded filomicelles that were originally 10-20mum long could be imaged as 2-5mum long

3 , fish communities from sites where kelp was originally abundant but subsequently disappeared became

4 The recorded data were originally acquired for the purpose of seizure predictio

5 may reflect the mechanism that cysteine was originally added into genetic code.

6 Permafrost originally aggraded simultaneously with peat accumulatio

7 Although originally aimed to capture REST activity, REST score wa

8 A total of 4861 records were identified originally and 1312 in an update.

9 at endocarditis model and identified a gene, originally annotated as "fruA" and renamed "bepA," putat

10 haliana genome contains four genes that were originally annotated as potentially encoding DNA gyrase:

11 oenzyme action are much more restricted than originally anticipated.

12 phenotypic effect is generally smaller than originally anticipated.

13 incorporating adaptive optics, a technology originally applied in astronomical telescopes to combat

14 human NK cell diversity is much broader than originally appreciated as a result of variegated surface

15 was coined the Imbrium Sculpture, and it was originally argued that it must have been formed by a gia

16 hat although religious beliefs and practices originally arose as nonadaptive by-products of innate co

17 ion of the direct detection assay, developed originally as a blood test for vCJD, for the detection o

18 otype appears to be segregating in pedigrees originally ascertained for schizophrenia.

19 Preschoolers 3-5 years of age were originally ascertained from primary care and day care si

20 consecutive mcFISH analyses, we assigned the originally assembled 32 pseudomolecules (supercontigs) o

21 Of 61 children originally assessed, 44 (21 [48%] male and 23 [52%] fema

22 ut have also prompted us to suggest that the originally assigned absolute configurations of chiral po

23 , patients taking siponimod continued at the originally assigned dose and patients taking placebo wer

24 his work serves to confirm the structure (4) originally assigned to discoipyrrole D.

25 Between 2 and 5 years, the group originally assigned to ranibizumab for 2 years lost more

26 et, although all patients continued on their originally assigned treatment.

27 orm of canine cone-rod dystrophy (cord1) was originally associated with a homozygous insertion in RPG

28 Coxsackievirus A24 (CV-A24) was not originally associated with human disease, but in 1970 a

29 Protein folding in the cell was originally assumed to be a spontaneous process, based on

30 ulvenes are a unique class of compounds that originally attracted attention due to their propensity t

31 piratory dysfunctions caused by obesity were originally attributed to mechanical factors; however, re

32 -rich metabolites and it has been suggested, originally based on in vitro data, that astrocytes provi

33 The pyrroles have originally been designed as hybrids of the antitubercula

34 least part of meteoritic merrillite may have originally been H(+)-bearing whitlockite with implicatio

35 pruce to lower elevations where past logging originally benefited northern hardwood species indicates

36 lations uncover a ternary complex, where the originally bound Fis protein is partially dissociated fr

37 ict that an OMIT window which does not exist originally can appear in weak optomechanical coupling an

38 Although the antiviral kinase PKR was originally characterized as a double-stranded RNA activa

39 Originally characterized as a hormonal and starvation re

40 SATB1, which contains two CUT domains, was originally characterized as a T cell-specific genome org

41 Originally, ChloCs have been engineered from cation cond

42 Originally, chloroplast retrograde signals in plants wer

43 Dystonia was originally classified as a basal ganglia disease.

44 ing modern sequencing technologies, 20 cases originally classified as having wild-type tumors underwe

45 Resequencing studies of 20 cases originally classified as KIT/PDGFRA wild-type GIST revea

46 PANDA was originally coded in C ++.

47 The term "exposome" was originally coined in 2005 and defined as the totality of

48 medically important NPs produced by bacteria originally collected from natural environments around th

49 of Cooper pairs forming a superconductor was originally conceived as being translationally invariant.

50 g and completed studies (including those not originally concerned with iodine) may provide an efficie

51 ntiferromagnet on the triangular lattice, as originally considered by Anderson.

52 Quantum steering, a fundamental notion originally considered by Schodinger, has also recently r

53 ethod is some six to seven times larger than originally considered.

54 The sub-wavelength aperture is originally coupled to asymmetric electrodes, which activ

55 The RANO working group was originally created to update response criteria for high-

56 G-CSF or CSF-3, originally defined as a regulator of granulocyte lineage

57 Nuclear receptors were originally defined as endocrine sensors in humans, leadi

58 Neoblasts, originally defined as undifferentiated cells residing in

59 ntatricopeptide repeat (PPR) protein family, originally defined by their RNA binding capacity, and fo

60 idence suggests that neuropilin 1 (Nrp1), an originally defined coreceptor for class 3 semaphorins an

61 The Milan criteria were originally defined in the context of adult liver transpl

62 seven functional classes of BTHS mutation as originally defined in yeast, are the same when modeled i

63 Our study originally demonstrates that a single administration of

64 ificant loss of neurofilament protein within originally deprived dLGN layers.

65 fective masses for warped energy dispersions originally derived by Kittel and others.

66 iency compared with possible deficiency were originally derived differently (experimental compared wi

67 n nonhuman primate (NHP) models of AIDS were originally derived from infected macaques during chronic

68 of R. typhi with the pRAM18dRGA plasmid that originally derives from Rickettsia amblyommatis and enco

69 Originally descended from endosymbiotic bacteria, their

70 We computed the old FSRP as originally described and a new model that used the most

71 ubstrate preference of AtGH3.5 is wider than originally described and includes the natural auxin phen

72 Originally described as a dopamine stabilizer, this mech

73 Originally described as a heat-labile fraction of the se

74 erpin protease inhibitor vaspin (serpinA12), originally described as an adipokine in adipose tissue.

75 While originally described as the damaging agent responsible f

76 Originally described by Japanese authors in the 1990s, T

77 w that the fusion protein generated from the originally described DISC1 translocation (DISC1-Boymaw)

78 in 1, DAN family BMP antagonist gene (GREM1) originally described in Ashkenazi Jews.

79 body disease (IBD) is an infectious disease originally described in captive snakes.

80 helial to mesenchymal transition (EndMT) was originally described in heart development where the endo

81 Many bacterial moonlighting proteins were originally described in medically, agriculturally, and c

82 Type VII secretion systems (T7SSs), originally described in mycobacteria, are now known to b

83 e m.3243A > G mitochondrial DNA mutation was originally described in patients with mitochondrial ence

84 n in vivo by mechanisms different from those originally described in vitro.

85 ifunctional protein that, in addition to its originally described role in protein import, is able to

86 n using post-transplant cyclophosphamide was originally described using bone marrow (BM).

87 e lacking and it is also unknown whether the originally described wing-spot patterns have persisted o

88 The VLMC originally designed for long sequences was extended to a

89 We originally designed the trial to test whether long-term

90 mized, placebo-controlled trials, which were originally designed to examine the efficacy of metformin

91 Originally designed to provide a unified standard of tri

92 CellNet was originally designed to work with human or mouse microarr

93 otal 25-hydroxyvitamin D concentrations were originally determined by ELISA and calibrated to a chemi

94 The SBiz imidates have been originally developed as a new platform for active-latent

95 at the unifying theory of thermal convection originally developed by Grossmann and Lohse for Rayleigh

96 In this study, a LFI, originally developed by the Naval Medical Research Cente

97 um species using an Fe-based catalyst system originally developed for alkyl halides.

98 Originally developed for bacterial cells, it has also be

99 RELION was originally developed for cryo-EM single-particle analysi

100 sis methods and 3D reconstruction approaches originally developed for cryogenic electron microscopy o

101 These techniques were originally developed for flat conducting surfaces, but t

102 In fact, a theoretical model originally developed for force-driven, two-dimensional D

103 ocesses at electrode/electrolyte interfaces, originally developed for homogeneous liquid mercury or m

104 We use an anticipatory looking test (originally developed for human infants) to show that thr

105 dulation, coding and transmission techniques originally developed for linear communication systems.

106 m of neuroplasticity whereby neural elements originally developed for one purpose are put to multiple

107 Significantly, the FEP+ approach, while originally developed for relative binding free energies

108 ass of nonlinear models by extending methods originally developed for studying observability.

109 Although originally developed for supervised analyses, i.e., to t

110 tificial iris anterior chamber implants were originally developed for therapeutic purposes but have b

111 Originally developed for tree-ring data, crossdating is

112 te that vitamin E-derived designer micelles, originally developed for use in synthetic chemistry, are

113 controls" (causal impact) method, which was originally developed for website analytics and social sc

114 Originally developed in the context of protein folding,

115 ility of the somatic pain pattern (which was originally developed on thermal pain) to mechanical and

116 Arbidol (ARB) is a synthetic antiviral originally developed to combat influenza viruses.

117 that a spiking neural model of this circuit originally developed to describe fruitfly (Drosophila me

118 Duplex sequencing was originally developed to detect rare nucleotide polymorph

119 generated using a unique framework that was originally developed to infer isoform functions.

120 Vaccines were originally developed to prevent or ameliorate infectious

121 Glycan Reader was originally developed to simplify the reading of Protein

122 mentary on this article.Antipsychotic drugs, originally developed to treat schizophrenia, are used to

123 We invoke an analytical model, originally devised for graphene macroscopic deformations

124 Ecdysis-triggering hormone (ETH) was originally discovered and characterized as a molt termin

125 Semaphorins, originally discovered as axon guidance cues in neural de

126 ure of the May-Wigner instability transition originally discovered by local linear stability analysis

127 Although originally discovered in 3D structures, circular dichroi

128 Originally discovered in a quest for biodegradation of a

129 light-activated nonselective cation channel originally discovered in Chlamydomonas reinhardtii.

130 The dual chemistry of ARD was originally discovered in the bacterium Klebsiella oxytoc

131 hat a growing number of polycistronic genes, originally discovered in viruses, are being identified w

132 Our results originally document that dried plasma is appropriate for

133 Originally driven by pushing technological limits, it ha

134 Overall, the sites participating in TENOR II originally enrolled 1230 patients in TENOR I.

135 The 41 individuals with epilepsy were originally enrolled in the Turku Adult Childhood Onset E

136 ce as a function of structure and solvent as originally envisaged by Leffler and Hammond.

137 esentative models for large protein families originally envisioned as the goal of the Protein Structu

138 particular, we show that this signature, as originally envisioned, may not always be present in a ch

139 , we tailored an optical biosensor approach, originally established in vitro.

140 Although the originally Eurasian-wide distribution suggests a pre-ada

141 that paired fins (and hence tetrapod limbs) originally evolved via transformation of gill arches.

142 stimulated emission depletion (STED) imaging originally evolved, how it compares to other optical sup

143 structure and configuration could have been originally favoured.

144 f them induces synaptic competition with its originally fitted parameters.

145 e elapsed since the mobilized carbon (C) was originally fixed from the atmosphere and to infer the tu

146 Originally found in a Scottish family with diverse menta

147 Green Fluorescent Protein (GFP) was originally found in cnidarians, and later in copepods an

148 cal PLR requires the pigment melanopsin [5], originally found in intrinsically photosensitive retinal

149 ted copy and/or an episome, while SEGS-2 was originally from the cassava genome but now is encapsidat

150 is accelerating at present - as was inferred originally from the Hubble diagram of Type Ia supernovae

151 ng and provide evidence that this domain was originally gained through exonization.

152 of 5746 NHANES participants had optic images originally graded.

153 The pha-1 gene of Caenorhabditis elegans was originally heralded as a master regulator of organ diffe

154 ematic elucidation of complete networks than originally hoped.

155 This enzyme was originally identified as a 3' --> 5' exonuclease, but we

156 Although originally identified as a B cell differentiation factor

157 CD6 was originally identified as a marker for T cells and was la

158 Metastasis Suppressor 1 (MTSS1) was originally identified as a metastasis suppressor protein

159 BRD7 was originally identified as a novel bromodomain gene and a

160 Type III IFNs were originally identified as a novel ligand-receptor system

161 f Malat1, a long noncoding RNA that has been originally identified as a prognostic marker for non-sma

162 RABEP2 function was originally identified as a Rab5 binding protein.

163 t that scaffold attachment factor A (SAF-A), originally identified as a structural nuclear protein, i

164 The eukaryotic translation factor eIF5A, originally identified as an initiation factor, was later

165 Cactin was originally identified as an interactor of the Drosophila

166 Although originally identified as an oncogene, Tropomyosin-relate

167 GPR119 was originally identified as an orphan beta-cell receptor; h

168 Originally identified as an orphan SULT by computational

169 Myeloid translocation genes (MTGs), originally identified as chromosomal translocations in a

170 ly stacking protein of 55 kDa (GRASP55) were originally identified as Golgi stacking proteins; howeve

171 Caspases were originally identified as important mediators of inflamma

172 Although chemokines and their receptors were originally identified as mediators of inflammatory disea

173 evolutionarily conserved proteins that were originally identified as modulators of actin-dependent p

174 The Salmonella-specific CueP-coding gene was originally identified as part of the Cue regulon under t

175 Amyloid precursor protein (APP) was originally identified as the source of beta-amyloid pept

176 nesin-like protein Smy1 of budding yeast was originally identified by the ability of elevated levels

177 n is an historically important lethal stress originally identified during seminal genetic experiments

178 Because PMP22 was originally identified in fibroblasts as growth arrest sp

179 We show here that KHARON, a protein originally identified in Leishmania parasites, interacts

180 main and a compact headpiece domain that was originally identified in villin.

181 Originally identified in yeast, transport protein partic

182 Linc-RoR was originally identified to be a regulator for induced plur

183 Of the 85 studies originally identified, 24 studies were included in the f

184 cently described to be far more complex than originally imagined.

185 APTANI builds on AptaMotif algorithm, originally implemented to analyze SELEX data; extends th

186 lated by a group of core proteins identified originally in flies to coordinate epithelial planar cell

187 Some 24%, 59%, and 68% of children originally in the atropine 0.01%, 0.1%, and 0.5% groups,

188 pathways have developed from compact systems originally inherited from an archaeal ancestor.

189 isk," which was based on a systematic review originally initiated by the National Heart, Lung, and Bl

190 Therefore, we herein originally introduce different reliable bioanalytical pr

191 to "levels of evidence" based on guidelines originally introduced by Wright et al. (2003).

192 lasticity.A skyrmion is a topological object originally introduced to model elementary particles and

193 nd platforms for various interesting physics originally investigated in quantum contexts and then, on

194 t allele in mid1ip1l fails to complement the originally isolated aura maternal-effect mutation, confi

195 oacidophilic archaeon Metallosphaera prunae, originally isolated from an abandoned uranium mine, ceas

196 etermine differences between E. coli strains originally isolated from dairy cattle with transient and

197 mma-proteobacterium Acinetobacter bereziniae originally isolated from human clinical specimens.

198 Micromonospora Lupac 08, originally isolated from Lupinus re-enters root tissue,

199 s Fibrobacter contains cellulolytic bacteria originally isolated from the rumen.

200 st virulent on the host from which they were originally isolated.

201 Originally its function was thought to be related to the

202 to determine how the diagnosis of asthma was originally made in the community.

203 and demonstrate its utility in revisiting an originally manual analysis from the publication record,

204 We evaluated the impact of standardizing the originally measured serum total 25-hydroxyvitamin D (25(

205 erformed worse than datasets with these data originally missing.

206 Although the cells were originally named 'Treg' to reflect immunoregulatory role

207 For instance, if an originally neutral event is repeatedly followed by an ev

208 at elevates the firing rate of a neuron, the originally neutral event will eventually also elevate th

209 ion transporter (OAT) family: OAT1 (SLC22A6, originally NKT) and OAT3 (SLC22A8).

210 organic anion transporter 1 (Oat1, Slc22a6, originally NKT), a major kidney-expressed drug transport

211 The functions of DCs were originally obscured by their overlap with other mononucl

212 miniscent of the metabolic memory phenomenon originally observed for persistent complications in diab

213 0.83-1.05; P = .25) was comparable with that originally observed in ACCORD (HR, 0.92; 95% CI, 0.79-1,

214 oter region variation and protein expression originally observed in strains from Colombia.

215 ecialized feeding on plants, including genes originally obtained via horizontal gene transfer from fu

216 ner, thus turning this novel chain reaction, originally occurring spontaneously in low yields, into a

217 Mutations originally only detected in lavage fluid fractions were

218 xpands but does not obliterate the functions originally performed by the recycled circuit, allowing f

219 The originally planned sample size was 660 patients, but the

220 suggesting that these valleys may have been originally populated from areas other than the Tibetan p

221 ce that effect sizes may be more modest than originally posited, with increasing evidence of polygeni

222 Such nontrivial states were originally predicted and discovered in condensed matter

223 w between sympatric strains, including those originally present at low inoculum.

224 type were found in the HN3 batches that were originally present in the reagent stocks and presumably

225 chromosomes are not simply remnants of genes originally present on the proto-sex-chromosome that esca

226 ent are consistent with cleavage of proteins originally present.

227 sulted in a BCVA worse than when the patient originally presented preoperatively.

228 nderwent surveillance, as well as update the originally presented surveillance protocol.

229 We describe a rare presentation of botulism originally presenting with exclusively unilateral crania

230 re numerosity processing takes over circuits originally processing space.

231 ypothesis presupposes that abiotic reactions originally produced nucleotides, the monomers of RNA and

232 ation through coherence (CTC) hypothesis was originally proposed 10 years ago, stating that two group

233 Here we evaluate the hypothesis, originally proposed almost 1 century ago, that most ID i

234 a potential allene-generating functionality originally proposed by Abeles, is now available in a qua

235 Immune response (Ir) genes, originally proposed by Baruj Benacerraf to explain diffe

236 (AZOOR) identified using the classification originally proposed by J.

237 to walk the derivative chromosome" signature originally proposed by Korbel and Campbell (2013).

238 3R,5S,6S,7R,11S,14R) is enantiomeric to that originally proposed by the isolating group.

239 Paradoxically, at the originally proposed cell-type level, Peters' rule remain

240 lenged the prevailing s +/- pairing scenario originally proposed for iron pnictides containing both e

241 patient may have been caused by secretin as originally proposed in 1968 and that secretin may act as

242 Newborn, and Child Survival has reached its originally proposed lifespan.

243 ctable bias between subgenomes; however, the originally proposed link between these two classes and w

244 er estimations on cell types compared to the originally proposed method by Houseman et al.

245 The originally proposed reaction mechanism (Houk) involves a

246 nyl)ethyl]-1,2,3,4-tetrahydroqui noline, the originally proposed structure of the Hancock alkaloid (-

247 High-entropy alloys were originally proposed to benefit from phase stabilization

248 D1492, that is annotated as a kinase and was originally proposed to promote sporulation by directly p

249 RFT1 was originally proposed to translocate the glycolipid Man5Gl

250 thus consuming much of the reducing capacity originally provided by the Fe(0)).

251 Nevertheless, the originally published FASP method has been criticized by

252 The originally published version of this Article contained a

253 In the originally published version of this Article, incorrect

254 In the version of this Letter originally published, the authors incorrectly stated tha

255 In the version of this Perspective originally published, the name of co-author Paul de Figu

256 The children were originally randomised in the following groups: nutrition

257 participants and continued metformin in the originally randomized metformin group.

258 values rapidly equalized among participants originally randomized to fenofibrate or placebo.

259 the primary study outcome among participants originally randomized to fenofibrate vs placebo (HR, 0.9

260 .3-6.4), with 52% on NVP and 88% on LPV/r as originally randomized.

261 Of those patients originally randomly assigned to trastuzumab emtansine, 2

262 eleasing factor binding protein (CRF-BP) was originally recognized as CRF sequestering protein.

263 Originally recognized for their direct induced toxicity

264 The population sample was originally recruited in adolescence: here we report the

265 derived) nitrate drives the redox shift from originally reducing toward oxidizing environments, when

266 CASE PRESENTATION: The patient was originally referred to our centre because of a deep unil

267 oscience research, particularly since it was originally rejected by the Journal!

268 ed parameters (q = 6, p = 12, respectively), originally related by a factor of two for simplicity of

269 atients generally recall more pain than they originally report, with ratings of pain related to state

270 Chaetognath grasping spines, originally reported as conodonts, occur worldwide in man

271 TaqII was originally reported to recognize two different asymmetri

272 overlap with NRG1 and is more extensive than originally reported, including expression in the striatu

273 for phenolic compounds at lower levels than originally required for enhanced functional properties.

274 Our data suggest that genes likely originally selected for competitive purposes also genera

275 ever, these transgenic Ig specificities were originally selected for their ability to recognize insul

276 After a 2003 serosurvey, 130 originally seronegative children received one dose of vi

277 s-and that they have lost the Hox genes that originally specified this region.

278 alysis indicated that the genotype F viruses originally spread from the Liaoning and Shandong provinc

279 oughnut-shaped molecular structure, PCNA was originally studied for its role in stimulating DNA polym

280 ual pertussis vaccine formulations, and many originally studied formulations are now unavailable.

281 Although the analytical approach was originally tailored to achieve reliable results only for

282 These stripes were originally taken as evidence of the directed dorsoventra

283 This population, originally termed "Ly-1" and now "B-1," has received ren

284 Originally, these peptides were believed to be solely de

285 se LPS causes both fever and hypothermia, we originally thought that the DMH contained a single therm

286 Endemic scrub typhus was originally thought to be confined to the so called "tsut

287 Although the M-region of Sac3 was originally thought to encompass residues approximately 2

288 This molecule was originally thought to function as a phytotoxin facilitat

289 glutamatergic, while GABAergic POA neurons, originally thought to mediate warm-induced inhibition of

290 rs are expressed in wider brain regions than originally thought.

291 esting their functions are more diverse than originally thought.

292 ve a much wider mean-free path spectrum than originally thought.

293 The field of artificial intelligence originally traveled down two roads, one of which emphasi

294 We demonstrate that an algorithm originally used for text mining, latent Dirichlet alloca

295 The originally used P4 benzylsulfonyl residue could be repla

296 Originally used to detect discrete neurotoxic damages, T

297 of LD into between-population components was originally used to investigate epistatic selection, we d

298 Originally viewed as DNA maintenance modules, TA systems

299 Cancer immunogenomics originally was framed by research supporting the hypothe

300 x (age(-0.129) [Corrected November 29, 2016: originally written as "age-129."]) x (sodium(0.972) ) x