ライフサイエンスコーパス: ortho position

1 ne phenyl group bearing a substituent in the ortho position.

2 sequently direct the nitrenoid to add to the ortho position.

3 creased by the presence of a chlorine in the ortho position.

4 icals on tyrosines with substitutions at the ortho position.

5 d that arylation proceeds selectively at the ortho position.

6 drogen bonds involving hydrogen atoms in the ortho position.

7 e keto-nitrile directs self-metalation at an ortho position.

8 set up for a 5-endo-trig cyclization at the ortho-position.

9 t of tyrosine and shows a preference for the ortho positions.

10 s direct the protonation to their respective ortho positions.

11 ferring hydrogen atoms between the ortho and ortho' positions (1,4-shifts of hydrogen atoms).

12 zides containing a substituent at one of the ortho positions (2,4-dimethoxyphenyl azide (1a) and 2-me

13 Generally, the reaction takes place in the ortho position, adjacent to the substituent.

14 , hitherto unstudied in pCps, between pseudo-ortho-positioned amides of a pCp-4,7,12,15-tetracarboxam

15 ariety of electron-withdrawing groups at the ortho position and evaluating their effects on oral bioa

16 n solution, it selectively protonates at the ortho position, and the resulting eta(2)-arenium species

17 es with electron donating groups at para and ortho positions are generally successful with our method

18 ation not only partially fails at one of the ortho positions but also is completely prevented by a co

19 When both ortho positions carry methyl substituents, cyclooctane a

20 Substitution at ortho positions caused the yield of C-H insertion produc

21 A sulfinyl group in an ortho position confers enough chemical and configuration

22 ing coordinating groups (particularly in the ortho position) gave lower, and in one case even reverse

23 resence of an oxygen-containing group at the ortho position (I) were important determinants for the a

24 uorines from the meta positions in 18 to the ortho positions in 20 reverses the binding orientation,

25 corresponds to direct bond formation between ortho positions in DPC, referred to as ortho,ortho' coup

26 hosphino)biphenyl, such as the unsubstituted ortho positions in the non-phosphine ring.

27 te is available or meta to the halide if the ortho position is already substituted.

28 te that in these analogues, hindrance at the ortho position is relaxed relative to poly(phenylenes).

29 ilization of the radical intermediate in the ortho-position is distinctly more favored for aromatic t

30 in the close proximity of the metal center (ortho position) is essential for the electrostatic facil

31 CYP3A4, resulting in oxygen transfer to the ortho position, is proposed.

32 bearing alkene-containing side-chains in the ortho-position) leads to formation of aliphatic aldehyde

33 the other hand, single substitutions at the ortho position led to the loss of binding affinity.

34 CHO coupled with substitution with CN in the ortho-positions makes the open and bridged radical appro

35 e-specific (13)C-(1)H enrichment of a single ortho position of aromatic amino acid side chains in an

36 Substitution at the ortho position of N-(3,4-dimethyl-5-isoxazolyl) benzenes

37 facile introduction of a phenyl group at the ortho position of phenols and anilines.

38 al H/D exchange for the hydrogen atom in the ortho position of pyridine and concomitant formation of

39 hat small electron-withdrawing groups on the ortho position of the anilide, i.e., chloro, acetyl, or

40 in, which is not further deprotonated at the ortho position of the aromatic ring.

41 cient, or when chelating substituents at the ortho position of the aryl ring are capable of binding w

42 udies demonstrated that substitutions at the ortho position of the aryl ring improved binding and fun

43 indicated that a pyrrole substituent in the ortho position of the side chain phenyl ring was most li

44 A symmetrical strap, attached to ortho positions of phenyl groups at opposing meso positi

45 ation of the ligand to have Ad groups at the ortho positions of the aryloxide arms is sufficient to s

46 Upon removing the steric bulk from the ortho positions of the N-aryl group of the thiazole-2-yl

47 y-2-butene increasing the steric bulk at the ortho positions of the N-aryl substituents results in ca

48 the alpha-position of the vinyl group or the ortho positions of the phenyl results in increased pheny

49 emissive peaks for the hydrogen spins at the ortho positions of the pyridine substrate (both free and

50 methylanilinium groups are introduced at the ortho positions of the TPP phenyls.

51 rin unit, carrying bromomethyl groups at the ortho positions of two trans-positioned meso-phenyl grou

52 further increased with a halogen atom in the ortho-position of the 1-phenyl ring.

53 eocenter and the sulfur functions located at ortho-position of the aryl group, on their stereoselecti

54 l electrophilic aromatic substitution of the ortho-position of the phenyl group adjacent to the oxime

55 xocyclic double bonds to direct links to the ortho-positions of both adjacent meso-phenyl groups.

56 h as fluorine are tolerated at the meta- and ortho-positions of the 4-phenoxy to retain a good in vit

57 the addition of a methyl substitutent at an ortho position on the beta-aromatic ring increases the a

58 owever, if the substituted nitrogen is in an ortho position relative to one acetylene linker and a pa

59 does not require prefunctionalization at the ortho-position since direct C-H activation is efficient.

60 f steric hindrance or electron donors at the ortho position to suppress the Tishchenko reaction, an u

61 rs do not allow chlorine substitution in the ortho-position to influence the prediction.

62 step, followed by a cycloalkenylation at the ortho-position to the amine functional group of the anil

63 ols the reaction occurred exclusively at the ortho-position to the benzamido functionality, in pyridi

64 nds strongly on the substituent -CH2X in the ortho-position to the tether.

65 Burkholderia cepacia G4 hydroxylates at the ortho position, toluene 3-monooxygenase (T3MO) of Ralsto

66 uence of the tBu group of the Mamx ligand in ortho position was evaluated by optimizing molecular str

67 Moreover, when one ortho position was labeled with deuterium, no selectivit

68 groups on the phenyl rings in all ortho and ortho' positions was immobilized on carbon nanotubes via

69 masked oxygen or nitrogen nucleophile in the ortho position were generated from thioacetals, using lo

70 ng an amide substituent in the meta, but not ortho position were up to 17-fold more potent inhibitors

71 l ligands bearing fluoro substituents in the ortho positions were used, the formation of the correspo

72 y, requires that the methoxy group be at the ortho position where it is positioned in the developing

73 d that hydroxylated toluene primarily at the ortho-position while converting naphthalene to 1-naphtho

74 requirement for chlorine substitution at the ortho-positions, with 2,2',3,5',6-pentachlorobiphenyl ha

75 idin-2-ylethynyl)-benzene, nitrogen atoms in ortho positions], with an IC(50) value in the nanomolar