ライフサイエンスコーパス: orthotopically

1 by grafting quail cranial paraxial mesoderm orthotopically.

2 erapy in K-ras or EGFR mutant tumors growing orthotopically.

3 r than 'assistance', as the device is placed orthotopically after excision of the entire ventricular

4 Kidneys were orthotopically allografted to immunodeficient mice.

5 A549 lung tumor cells were orthotopically and metastatically administered to Nu/nu

6 ssing red fluorescent protein were implanted orthotopically, and a red fluorescent protein-expressing

7 The intestines were orthotopically autotransplanted immediately (control gro

8 tastatic potential of sarcoma cells injected orthotopically, but the simultaneous restoration of all

9 gratory chick neural crest had been replaced orthotopically by quail cells, a population of neural cr

10 -refractory human prostate carcinoma growing orthotopically efficiently deliver viable metastatic cel

11 Orthotopically engrafted calpain 2 knockdown AC2M2 cells

12 s tumour growth and improves the survival of orthotopically engrafted mice implanted with human PTEN-

13 Animals with pancreatic tumors implanted orthotopically exhibited prolonged survival that was sig

14 f 22 rats, an incisor scaffold was implanted orthotopically following mandibular incisor extraction,

15 immune privileged tissue that, when grafted orthotopically, forms the anterior surface of the immune

16 are accepted spontaneously when transplanted orthotopically from B10 (H2b) or BALB/c (H2d) to C3H (H2

17 ve markers expression associated with CRC in orthotopically generated liver metastasis.

18 and Ki67 staining were observed between the orthotopically generated primary and liver metastatic tu

19 Serum samples from CB6F1 rejecters of orthotopically grafted C3H/Hej corneas were tested by EL

20 BL/6 (fully mismatched allogeneic) mice were orthotopically grafted onto BALB/c recipients.

21 course of angiogenesis was determined for an orthotopically growing human prostate tumor periodically

22 on of LOX eliminates metastasis in mice with orthotopically grown breast cancer tumours.

23 trated that, similarly to the clinical CRPC, orthotopically grown castration-resistant VCaP (CR-VCaP)

24 Orthotopically grown tumors and low-density cell culture

25 node and distant metastases in mice bearing orthotopically implanted "mesenchymal" UM-UC3 cells.

26 n overexpression increased the metastasis of orthotopically implanted 4T1 or tail vein-injected MDA-M

27 pancreatic tumor cell lines were surgically orthotopically implanted as tissue fragments in the body

28 Mice bearing orthotopically implanted astrocytoma cells with diminish

29 the tumor when injected intratumorally into orthotopically implanted breast tumors in mice.

30 ector was injected intratumorally into large orthotopically implanted HCC in immune-competent rats, r

31 cell survival proteins, and activate JNK in orthotopically implanted human colorectal cancer in a nu

32 Intravital images of orthotopically implanted human pancreatic tumors clearly

33 Orthotopically implanted human PC3-M PCa cells formed lu

34 postsurgical metastatic disease in multiple orthotopically implanted human tumor xenograft and synge

35 When orthotopically implanted in castrated nude mice, LNCaP-G

36 sly shown that in human neuroblastoma tumors orthotopically implanted in immunodeficient mice, stroma

37 genicity and metastasis forming ability when orthotopically implanted in nude mice.

38 verexpressing human breast cancer cells were orthotopically implanted in nude mice.

39 tic PC-3 human prostate tumors that had been orthotopically implanted in nude mice.

40 More importantly, when orthotopically implanted in nude mouse prostate, both 15

41 When orthotopically implanted in the skin of mice, B16F10 cel

42 In CXM, human breast cancer cells are orthotopically implanted into immunodeficient consomic s

43 line DU 145 and hepatocarcinoma LCI-D35 were orthotopically implanted into nude mouse prostate and li

44 afts were established, they were excised and orthotopically implanted into other male BALB/c nude mic

45 CT26 tumor cells were orthotopically implanted into the descending colon of C5

46 apacity for tumor growth and metastasis when orthotopically implanted into the lungs of SCID-beige mi

47 When these PDEF-expressing cells were orthotopically implanted into the mouse mammary gland, t

48 sfected, and IFN-beta-transfected cells were orthotopically implanted into the pancreas of syngeneic

49 l Ron expression, prostate cancer cells were orthotopically implanted into the prostates of either wi

50 Mammary tumor cells were orthotopically implanted into these distinct microenviro

51 e setting of medulloblastoma, spontaneous or orthotopically implanted lesions can be imaged, and tumo

52 umor efficacy was observed similarly against orthotopically implanted LNCaP human prostate carcinomas

53 Three mice bearing orthotopically implanted mammary tumors derived from tra

54 we provide evidence that the vasculature in orthotopically implanted melanoma arises from a preexist

55 the system was further evaluated by imaging orthotopically implanted murine colonic adenocarcinomas

56 e assessed the growth and vascularization of orthotopically implanted murine gliomas since they requi

57 In a mouse model of orthotopically implanted neuroblastoma cells, inhibition

58 Discosoma red fluorescent protein (RFP) and orthotopically implanted onto the pancreas of nude mice.

59 dministration of IL-4 cytotoxin in mice with orthotopically implanted ovarian tumors caused regressio

60 idol treatment also suppressed the growth of orthotopically implanted Panc-1 tumors by 80% by inducin

61 l dissemination and liver/lung metastasis of orthotopically implanted PanC-1-luc cells were significa

62 ostatic tumors established in nude mice from orthotopically implanted PC-3 LN4 prostate cancer cells

63 ng metastases, and lymphatic metastases from orthotopically implanted PC3LN3 prostate carcinoma.

64 astasis developing after surgical removal of orthotopically implanted primary tumors.

65 the DU-145 prostate carcinoma cell line and orthotopically implanted prostate tumor in nude rats.

66 an prostate carcinomas in male nude mice and orthotopically implanted renal carcinoma (RENCA) tumors

67 y relevant micrometastases originating in an orthotopically implanted tumor.

68 ollowing: (a) differences in ectopically and orthotopically implanted tumors (n = 10), (b) cohorts of

69 y delayed tumor growth of subcutaneously and orthotopically implanted tumors in nude mice, and was ac

70 Furthermore, growth of orthotopically implanted tumors in vivo is inhibited by

71 Here, we show that scid mice orthotopically implanted with breast cancer cells expres

72 Lastly, in vivo studies with mice orthotopically implanted with ENZA-resistant cells demon

73 icacy and improves survival of rats and mice orthotopically implanted with gliosarcoma tumors or glio

74 rious distant organs in the CS-exposed mice, orthotopically implanted with luciferase-transfected PC

75 In the in vivo studies, all the mice orthotopically implanted with MiPaCa-MUC4 cells develope

76 ting our in vitro observations, all the mice orthotopically implanted with PC-3-MIC-1 cells developed

77 nodeficient RAG1/MMP-9 double-deficient mice orthotopically implanted with tumor cells (P = 0.043) or

78 Further, orthotopically implanted xenografts of MCF10A-Kras-scr g

79 Induction of VEGF expression in orthotopically implanted xenografts that were initially

80 nodeficient mice (n = 5-7 per group) bearing orthotopically implanted, luciferase-positive human panc

81 breast cancer (DU4475, n = 8) were implanted orthotopically in athymic nude mice.

82 deficient) mice; or (2) corneas were grafted orthotopically in BALB/c eyes as intact corneas or as co

83 neas from BALB/c and BALB.B mice were placed orthotopically in eyes of C57BL/6 and beta-2 microglobul

84 first time, that mouse brain tumors can grow orthotopically in fish and serve as a platform to study

85 as/p53 mutant lung adenocarcinomas engrafted orthotopically in immunocompromised nude rats by targeti

86 ze of MDA-MB231 breast cancer tumors growing orthotopically in immunodeficient mice without noticeabl

87 etastasis of human pancreatic cancer growing orthotopically in nude mice and increased survival.

88 When these cells were injected orthotopically in nude mice, we found that the increased

89 idely throughout the skeleton when implanted orthotopically in nude mice.

90 uman MP TF activity in the plasma when grown orthotopically in nude mice.

91 th and lung metastasis of SN12-C cells grown orthotopically in SCID mice.

92 HT29 human colon cancer cells growing orthotopically in the cecum of nude mice expressed a hig

93 -small cell lung tumor xenograft established orthotopically in the lungs of SCID mice.

94 y tumor cells did not metastasize when grown orthotopically in the mammary fat pads of WT mice.

95 ine that had been isolated from tumors grown orthotopically in the prostate glands and regional lymph

96 a human prostate cancer xenograft implanted orthotopically in the prostate or s.c. in the flank.

97 ither heterotopically (out of continuity) or orthotopically (in continuity); the latter is believed t

98 rate its potential in cancer diagnosis in an orthotopically induced colorectal cancer (CRC) xenograft

99 of RAGE, we performed syngeneic studies with orthotopically injected breast cancer cells in wild-type

100 astatic mouse breast cancer cells (4T1) were orthotopically injected into the mammary fat pads of BAL

101 ivo, induction of Her-2/neu by castration in orthotopically injected LNCaP cells resulted in a progre

102 rved on proliferation in cell culture and in orthotopically injected mice, miR-135b was able to contr

103 nd Gelfoam sponge implants and the growth of orthotopically injected tumors.

104 ovariectomized, immune-competent female mice orthotopically injected with Py230 mammary tumor cells.

105 BALB/c tracheal grafts were transplanted orthotopically into allogeneic C57BL/6 recipients.

106 F344 kidneys were transplanted orthotopically into bilaterally nephrectomized LEW recip

107 le Lewis rats [LEW]-->LEW) were transplanted orthotopically into bilaterally nephrectomized recipient

108 cinoma cells transplanted subcutaneously and orthotopically into EphA2-deficient female mice displaye

109 ith BALB/c epithelium, and then transplanted orthotopically into high-risk eyes of BALB/c mice.

110 ved for 6 hr at 4 degrees C and transplanted orthotopically into isogeneic recipients.

111 ed at 4 degrees C for 24 h, and transplanted orthotopically into LEW recipients, followed by contrala

112 e transfected with EMMPRIN cDNA and injected orthotopically into mammary tissue of female NCr nu/nu m

113 ers from FL-treated donors were transplanted orthotopically into naive C3H (H2k) recipients.

114 Hamster livers, transplanted orthotopically into naive rats (controls), were rejected

115 ived of Langerhans' cells) were transplanted orthotopically into normal eyes of BALB/c mice.

116 ed aortas from uremic mice were transplanted orthotopically into normal mice, and the calcium content

117 times before their livers were transplanted orthotopically into normal or donor skin-presensitized C

118 from AAV9-MIS-treated mice were transplanted orthotopically into normal recipient mice, or when treat

119 When injected orthotopically into nude mice, the primary tumor volumes

120 When injected orthotopically into nude mice, TIMP-4 transfectants were

121 human ovarian cancer cells (A2780) implanted orthotopically into nude mice.

122 sion of human head and neck cancer implanted orthotopically into nude mice.

123 human colon cancer was surgically implanted orthotopically into nude mice.

124 mall cell lung carcinoma (NSCLC) xenografted orthotopically into nude mice.

125 ved mammary adenocarcinoma cells (Mat B III) orthotopically into syngeneic F344 rats with an intact i

126 nditioned tumor cells were then transplanted orthotopically into the brains of zebrafish acclimatized

127 and metastatic properties when transplanted orthotopically into the immunodeficient mice.

128 actor-transformed glial cells were engrafted orthotopically into the mice, the tumors that formed pro

129 njected subcutaneously, intraperitoneally or orthotopically into the ovarian bursa.

130 ession, the BxPC-3 cell lines were implanted orthotopically into the pancreas of nude mice.

131 Furthermore, when transplanted orthotopically into the prostate of nude mice, LNCaP cel

132 E) or TSP-1 were knocked down were implanted orthotopically into the thyroids of immunocompromised mi

133 ty or recipient haplotype, were transplanted orthotopically into unmodified C3H recipients.

134 2 mouse osteosarcoma cell line was implanted orthotopically into wild-type and NKT cell-deficient CD1

135 BALB/c donor corneas were grafted orthotopically onto C57BL/6, perforin knockout, or CD8(+

136 Tumors are implanted orthotopically or can be implanted ectopically.

137 e growth of PlGF-overexpressing tumors grown orthotopically or ectopically was impaired in all three

138 obarbital-treated (80 mg/kg/day), n = 17; 3) orthotopically placed (in intestinal continuity) grafts,

139 nuity) grafts, saline-treated, n = 5; and 4) orthotopically placed grafts, phenobarbital-treated, n =

140 Results from orthotopically recombining stromal WPMY1 cells with epit

141 The reseeded scaffolds are used to orthotopically replace the entire cervical oesophagus in

142 nts 1 to 3 are resected in the recipient and orthotopically replaced by a segment 2 to 3 allograft.

143 The CardioWest Total Artificial Heart orthotopically replaces both native cardiac ventricles a

144 5) or murine autografts (n = 5) were grafted orthotopically to athymic mice.

145 fection, the donor corneas were transplanted orthotopically to BALB/c or C57BL/6 recipients.

146 uc and mouse 4T1luc cell lines were injected orthotopically to establish breast carcinoma tumors in i

147 s from adult GFP transgenic mice and grafted orthotopically to full-thickness wounds on athymic mice.

148 PVG.R8 lungs were transplanted orthotopically to MHC class I-incompatible PVG.1U recipi

149 he implantation of TM40D mammary tumor cells orthotopically to the mammary gland; tumors grew within

150 system in which full-thickness human skin is orthotopically transferred onto severe combined immunode

151 ocured after 24 hr of in vivo incubation and orthotopically transplanted after 1 hr of cold ischemia

152 The liver grafts were orthotopically transplanted after 48 hr of hypothermic p

153 of CXCR4 significantly limited the growth of orthotopically transplanted breast cancer cells.

154 olon 38 adenocarcinoma tissue fragments were orthotopically transplanted by attachment to the surface

155 Further, orthotopically transplanted human glioblastoma tumours i

156 Aortic grafts were orthotopically transplanted in the Dark Agouti to Brown

157 Kidneys of Lewis (LEW) and F344 rats were orthotopically transplanted into bilaterally nephrectomi

158 The kidneys of Brown-Norway rats were orthotopically transplanted into bilaterally nephrectomi

159 racheal segments (five tracheal rings), were orthotopically transplanted into either syngeneic Balb/c

160 tic cancer cell line 168FARN, which was then orthotopically transplanted into mouse mammary fat pads,

161 Brown Norway tracheal segments were orthotopically transplanted into nonimmunosuppressed Lew

162 y of Wisconsin at 4 degrees C for 24 hr, was orthotopically transplanted into syngeneic recipient.

163 r NELP, ischemically damaged livers could be orthotopically transplanted into syngeneic recipients wi

164 model of de novo mammary tumor formation, we orthotopically transplanted invasive lobular carcinoma (

165 We orthotopically transplanted mouse tail skin allografts a

166 Orthotopically transplanted neoplastic organoids recapit

167 Orthotopically transplanted PIPKIgamma-depleted breast c

168 allografts, ACI or (ACIxLewis)F1 (F1), were orthotopically transplanted to Lewis recipients and then

169 expressing human breast tumor MDA-MB-435 was orthotopically transplanted to the mouse fat pad, where

170 mor size and prolonged survival of mice with orthotopically transplanted tumors; more than 50% of ani

171 etastatic PC3M-LN4 cells, the 22Rv1 line was orthotopically tumorigenic but not metastatic, despite l

172 n immune compromised mice, in which it grows orthotopically under the renal capsule, doubling its siz

173 were injected into mice (subcutaneously and orthotopically), we observed marked inhibition of tumor

174 l was then investigated in animals implanted orthotopically with 2 x 10(6) PC-3 cells.

175 ndirect pathways in BALB/c mice transplanted orthotopically with fully allogeneic C57BL/6 corneas.

176 ly into 6 athymic mice which were inoculated orthotopically with green fluorescent protein (GFP) expr

177 Mice were implanted orthotopically with MDA-MB-231 cells.

178 cifically in the mammary gland or inoculated orthotopically with the mouse mammary tumor cell lines M

179 in the growth of pancreatic tumors implanted orthotopically, with tumor volume measurements obtained

180 By contrast, Wilms tumor cells established orthotopically within the kidney were histologically acc

181 yngeneic tumor (Lewis lung carcinoma) and an orthotopically xenografted human breast carcinoma.

182 heir selective accumulation within tumors of orthotopically xenografted human pancreatic cancer in nu

183 the growth of H460 and A549 NSCLC cell lines orthotopically xenografted into the intrapulmonary inter

184 tumorigenicity and metastatic capability in orthotopically xenografted mice.

185 Efficacy of (+)-JQ1 was evaluated in an orthotopically xenografted model of MM.

186 of SK-N-BE (2).10 human neuroblastoma tumors orthotopically xenotransplanted into immunodeficient mic