ライフサイエンスコーパス: osmolality

1 ignificantly affected by contrast volume and osmolality.

2 a decreased urine volume and increased urine osmolality.

3 egardless of hemodynamic stability and serum osmolality.

4 th acute and chronic increases of body fluid osmolality.

5 of collecting duct epithelial cells in high osmolality.

6 ter is dependent on achieving a target serum osmolality.

7 smolality, and correct serum [Na+] and serum osmolality.

8 dewetting) resulting in increased tear film osmolality.

9 ake and urine volume, alongside higher urine osmolality.

10 nguishable from +/+ in BP, urine volume, and osmolality.

11 coiled-coil domain respond similarly to the osmolality.

12 ead, due to impaired growth at physiological osmolality.

13 entration and not to increased extracellular osmolality.

14 ProP activity is a sigmoidal function of the osmolality.

15 ers and all solutes increase with increasing osmolality.

16 correlated inversely with changes in plasma osmolality.

17 ) and biopolymers (crowding) with increasing osmolality.

18 ion was not affected by up- or downshifts in osmolality.

19 n serum and urinary glucose levels and serum osmolality.

20 (WT) mice while maintaining a similar plasma osmolality.

21 e during increases in extracellular K(+) and osmolality.

22 the growth rate of E. coli at high external osmolality.

23 plasmic volume regulation at low-to-moderate osmolality.

24 meters whose volume is controlled by luminal osmolality.

25 ia with an inappropriate decrease in urinary osmolality.

26 genes can be modulated by the extracellular osmolality.

27 y a hormone signal of nutrient levels and by osmolality.

28 consumption, even prior to changes in blood osmolality.

29 lity at a faster rate than changes in ocular osmolality.

30 ater uptake and resumption of growth at high osmolality.

31 nt with increases in fluid intake and plasma osmolality.

32 hysiological levels and inhibited by reduced osmolality.

33 ns showed reasonable agreement with measured osmolality.

34 minimal medium over a wide range of external osmolalities (0.03 to 1.8 osmol).

35 -12 grown over a wide range of high external osmolalities (1.02-2.17 Osm) in MOPS-buffered minimal me

36 us infusion of HYPER saline increased plasma osmolality (294 +/- 3 to 316 +/- 5 mOsm kg(-1) H2O, P </

37 eras were functional at normal extracellular osmolality (300 mosmol/kg), but the activity only of the

38 ite better renal free water excretion (urine osmolality 343+/-101 mOsm/kg versus 475+/-136; P<0.001).

39 +/+) mice (1.6 ml/day) and had reduced urine osmolality (400 vs. 1800 mosmol).

40 by which they are accumulated; 4) sensors of osmolality; 5) the signaling pathways involved; and 6) m

41 of the equilibrium constant on the solution osmolality, 60 +/- 13 waters are acquired in the complex

42 plasma renin concentration, urine volume and osmolality, ability to concentrate and dilute urine, and

43 metabolites are largely responsible for leaf osmolality above a baseline level (approximately 300 mm)

44 Further, we found that HSD elevated skin osmolality above plasma levels.

45 However, the osmolality adjusted sum, U-As(IMM), of urinary inorganic

46 rapeutic concentrations in the kidney, urine osmolality after administration of 1-deamino-8-D-arginin

47 g nutritional status to the control of blood osmolality, although the mechanism of this systemic cros

48 des for water rewards as a function of blood osmolality (an objective measure of how much water the s

49 ndance is tightly regulated along a range of osmolalities and that AQP5 reduction by extracellular hy

50 Under basal conditions, plasma and urine osmolalities and urine volumes were similar between CD-K

51 ced similar antidiuresis and increased urine osmolality and aquaporin-2 abundance.

52 gnificant increase in water retention, urine osmolality and aquaporin-2 expression and phosphorylatio

53 There was a strong correlation between serum osmolality and attenuation of stroke-associated increase

54 ween the regulation of blood volume/pressure/osmolality and blood glucose.

55 ement and differential bias between measured osmolality and calculated osmolarity.

56 (MNCs) of the supra optic nucleus can sense osmolality and control the synthesis and secretion of va

57 ntrations were higher in samples with raised osmolality and copeptin (surrogate marker for AVP).

58 ukaryotes, bacteria undergo large changes in osmolality and cytoplasmic pH.

59 ls, water and sodium reabsorption, and urine osmolality and decreased urine output (P </= 0.04, excep

60 Differences in responses to osmolality and direct depolarization in vitro indicate t

61 tectant (efficient at increasing cytoplasmic osmolality and growth rate) and a compatible solute (wit

62 P levels, free water reabsorption, and urine osmolality and increased urine output (P </= 0.03 except

63 ls, water and sodium reabsorption, and urine osmolality and increased urine output, while raxibacumab

64 ls and the correlation between osmole gap or osmolality and mannitol serum concentrations in ten NNIC

65 mpared with control rats at comparable serum osmolality and plasma vasopressin concentrations.

66 n and calcium content, while increasing milk osmolality and protein concentrations.

67 re, we analyzed serial measurements of serum osmolality and serum sodium, plasma arginine vasopressin

68 urinary pH (P < 0.001) and decreased urinary osmolality and urea concentration (P < 0.001) in SD rats

69 Hydration status (plasma osmolality and urine specific gravity) and body composit

70 than resting indices regardless of contrast osmolality and volume (P<0.001 for all groups).

71 which in turn influence the osmotic (plasma osmolality) and blood volume-dependent compensatory thre

72 To obtain turgor pressure, intracellular osmolalities, and cytoplasmic water activity of Escheric

73 plasmic osmolalities greatly exceed observed osmolalities, and the efficiency of GB as an osmolality

74 tter with mannitol serum concentrations than osmolality, and although it cannot predict a specific ma

75 augment free water clearance, decrease urine osmolality, and correct serum [Na+] and serum osmolality

76 uding standardization by urinary creatinine, osmolality, and flow rates, and inclusion of these metri

77 rbs that load passively, have low K(p), high osmolality, and high concentrations of transport sugars

78 bserved marked antidiuresis, increased urine osmolality, and increased solute-free water reabsorption

79 The reference standard was serum osmolality, and index tests included USG, urine color, u

80 ively load sucrose alone have high K(p), low osmolality, and low concentrations of sugars and total p

81 The changes in milk calcium content, milk osmolality, and milk protein concentration were mitigate

82 ificantly higher symptom scores, higher tear osmolality, and shorter TBUT than healthy controls.

83 o significant differences in urinary volume, osmolality, and sodium content after the three infusions

84 genic site O when exposed to extremes of pH, osmolality, and temperature.

85 Urine volume, urine osmolality, and urinary excretion of sodium and creatini

86 , blood pressure, serum and urine sodium and osmolality, and urine output.

87 n growth were measured, and turgor pressure, osmolality, and water potentials (psi) were determined (

88 that contributions of individual solutes to osmolality are additive and using in vitro osmotic data

89 Plasma and urinary osmolality are decreased in FP KOs that exhibit mild pol

90 n a liquid environment whose composition and osmolality are maintained within tight limits.

91 y expressed TRPM8 was activated by increased osmolality around physiological levels and inhibited by

92 Analysis of osmolality as a function of solute and DNA concentration

93 greater urine flow rate and decreased urine osmolality as compared with control rats at comparable s

94 flow rates and decreased urine and medullary osmolality as compared with CTL and HT+T rats at compara

95 At constant external osmolality, aspiration increases the surface area of the

96 ally accepted that dialysis may lower plasma osmolality at a faster rate than changes in ocular osmol

97 normalities, mutant mice exhibited low urine osmolality at baseline and after water restriction and a

98 are confronted with changes in extracellular osmolality at various sites, including the aqueous layer

99 .11; 95% CI, 0.01 to 0.20; P=0.03) and urine osmolality (beta=0.08; 95% CI, 0.05 to 0.10; P<0.001).

100 Changes in body mass, urine osmolality, body temperature, and thirst were monitored.

101 osmolalities, and the efficiency of GB as an osmolality booster decreases as the amount of cytoplasmi

102 lated to the reciprocal of the extracellular osmolality (Boyle van't Hoff relationship) with an osmot

103 ns that increased linearly with rising serum osmolality but had abnormally low osmotic thresholds (ty

104 eurons respond to increases in extracellular osmolality but the mechanism responsible for excitation

105 ProP activity at high osmolality, but not the osmolality, yielding half-maxima

106 rity, which is an indirect estimate of serum osmolality, but which serum osmolarity equations best pr

107 Bacteria respond to increasing medium osmolality by accumulating organic solutes that are comp

108 d urine output by 3-5-fold and reduced urine osmolality by approximately 2-fold compared to vehicle c

109 The spheroplasts can adjust their internal osmolality by increasing their volumes more than three t

110 Moderate osmolality can stimulate bacterial growth at temperature

111 ages, parasites are able to survive dramatic osmolality changes between its vector, fresh water, and

112 ed whole-plant hydraulic conductance (K(p)), osmolality, concentrations of polar metabolites, and key

113 f cFFR between patients receiving low or iso-osmolality contrast (n=574 versus 189) and low or high c

114 s and with intravenous administration of low-osmolality contrast material in 112.

115 Intravenous administration of low-osmolality contrast material is significantly associated

116 ntrast medium iopamidol with that of the iso-osmolality contrast medium iodixanol in high-risk patien

117 s exist of the renal tolerability of the low-osmolality contrast medium iopamidol with that of the is

118 ticosteroid premedication regimen before low-osmolality contrast-enhanced CT for a prior allergic-lik

119 e, water will readily flow inside the higher osmolality cytoplasm.

120 d to be both time-dependent (> or =24 h) and osmolality-dependent (> or =500 mosmol/KgH(2)O).

121 expression by hyperosmolality in a time- and osmolality-dependent fashion.

122 ch functions as the osmosensing core through osmolality-dependent helical stabilization.

123 This osmolality-dependent relocation to the division apparatu

124 However, contrast volume and osmolality do affect the sensitivity and specificity of

125 Further increases in osmolality drove formation of two chemically distinct da

126 reduced urine flow and two-fold higher urine osmolality during the first 12 hours of treatment compar

127 An elevation in plasma osmolality elicits a complex neurohumoral response, incl

128 We investigated the mechanism by which high osmolality enhances the thermotolerance of Salmonella en

129 Here we show that small increases in osmolality excite isolated mouse dorsal root ganglion (D

130 on between copeptin concentrations and serum osmolality existed in 68 healthy controls, with a mean o

131 (symptom questionnaire) and objective (tear osmolality, fluorescein tear break-up time [TBUT]) measu

132 evious extrapolations and, combined with new osmolalities from bathyal and abyssal fishes, predict is

133 We find that raising osmolality from 300 to 500 mosmol/kg by adding NaCl acti

134 terase (GPC-PDE) activity and that elevating osmolality from 300 to 500 mosmol/kg by adding NaCl or u

135 Direct measurement of tissue osmolality further revealed lymphoid tissues to be hyper

136 In the outer medulla, the osmolality gradient arises principally from vigorous act

137 fficient to form anion channels activated by osmolality gradients.

138 tle cytoplasmic water, predicted cytoplasmic osmolalities greatly exceed observed osmolalities, and t

139 under the curve of cFFR in the low- and iso-osmolality groups (0.938 versus 0.957; P=0.40) and in th

140 rall accuracy of cFFR for the low versus iso-osmolality groups were 73%, 93%, and 85% versus 87%, 90%

141 had impending or current dehydration (serum osmolality >/=295 mmol/kg).

142 f NU-AGE participants were dehydrated (serum osmolality >300 mOsm/kg).

143 Osmolality had the lowest correlation with mannitol conc

144 Changes in extracellular osmolality have been shown to alter gene expression patt

145 Although USG, urine color, and urinary osmolality have been widely advocated for screening for

146 ecific gravity (USG), urine color, and urine osmolality have been widely advocated for screening for

147 ich physiological or pathological changes in osmolality impact chondrocyte function remain unclear.

148 Notably, basal urine osmolalities in both wild-type and UT-A1(+/+)/UT-A3(-/-)

149 17-AAG increased urine osmolality in AQP2(T126M/-) mice by >300 mosmol but had

150 The possibility that increased plasma sodium/osmolality in AV3V-lesion rats down-regulated cardiac be

151 s produced a partial increase in the urinary osmolality in homozygous individuals and decreased their

152 lso increased urine output and reduced urine osmolality in mice given free access to water.

153 The increase in urine osmolality in response to water deprivation or vasopress

154 erum osmolarity equations best predict serum osmolality in the elderly is unclear.

155 ignificantly decreased, as was the medullary osmolality in the GD rats versus control rats.

156 UTB(inh)-14 did not reduce urine osmolality in UT-B knockout mice.

157 PLP-null myelin lamellae and fluctuations in osmolality in vivo might underlie slowing of conduction

158 However, the urine osmolality increase was greater within the physiological

159 t 1.67 where it remained unchanged even when osmolality increased further to 500 mosmol kg(-1).

160 Urinary osmolality increased with increasing BMI.

161 ontrast, alpha increased steadily to 0.42 as osmolality increased.

162 ction of rats or mice led to increased urine osmolality, increased Sgk1 expression, increased express

163 High osmolality increases phosphorylation at T135 in HEK293 c

164 As osmolality increases, we observe that the amount of cyto

165 e distribution of D(peri) broadens as growth osmolality increases.

166 pling together with measurements of leaf sap osmolality indicate a passive symplasmic loading type.

167 outflow with concomitant reduction of urine osmolality, indicating a purely aquaretic effect associa

168 Hyper-osmolality induced via 2% hypertonic saline ingestion si

169 nificantly decreased, whereas sustained hypo-osmolality induced via d-d-arginine VP and liquid diet i

170 Bacterial responses to decreasing osmolality involve mechanosensitive channels.

171 Intravenous low-osmolality iodinated contrast material had a significant

172 Intravenous low-osmolality iodinated contrast material is a nephrotoxic

173 derwent contrast-enhanced CT with either iso-osmolality iodixanol (n = 61) or low-osmolality iopromid

174 her iso-osmolality iodixanol (n = 61) or low-osmolality iopromide (n = 56).

175 attenuated with hypertonic saline when serum osmolality is >350 mOsm/L without adverse effect on mort

176 Interstitial osmolality is a key homeostatic variable that varies dep

177 Because hyper-osmolality is a potent stimulus for VP and OT release, t

178 s relatively large, we find that cytoplasmic osmolality is adequately predicted by assuming that cont

179 Serum osmolality is an accurate indicator of hydration status

180 ity of the conformational change to solution osmolality is consistent with a structural model predict

181 Plasma volume is expanded and plasma osmolality is decreased, yet vasopressin secretion in pr

182 ease in glucose, electrolytes, and resultant osmolality is desired.

183 mutant at high temperature in medium of high osmolality is due to the block in trehalose synthesis, w

184 secretory glands, sites where extracellular osmolality is known to fluctuate.

185 Ambient tonicity (effective osmolality) is the prominent signal for TonEBP in a bidi

186 g the activation of SLC26A7 activity by high osmolality, it is proposed that SLC26A7 may play an impo

187 O was due to (a) a direct effect of the K(+)/osmolality (K(hyper)) on the endothelium or (b) a 'permi

188 -induced anorexia in which increasing plasma osmolality leads to a centrally generated reduction in f

189 an that in wild-type litter mates, and urine osmolality (<275 milliosmol) was much lower than in wild

190 d low-dosage and high-dosage gadodiamide and osmolality-matched saline controls.

191 However, contrast media volume and osmolality may affect the degree of hyperemia and theref

192 ith obesity, and that urinary creatinine and osmolality may be colliders on the causal pathway from a

193 s of repressor-DNA complexes with increasing osmolality may contribute to the ability of Escherichia

194 kage, as well as the change in extracellular osmolality, may have a significant impact on chondrocyte

195 Osmolality measurements documented the non-idealities of

196 profiles, spleen function biomarkers, urine osmolality, neurodevelopment, transcranial Doppler ultra

197 ession analysis showed that neither contrast osmolality nor volume affected the overall accuracy of c

198 Preliminary extrapolation of osmolalities of predicted isosmotic state at 8,000-8,500

199 ave a TMAO content of 386 +/- 18 mmol/kg and osmolality of 991 +/- 22 mOsmol/kg.

200 the VR agonist dDAVP did not increase urine osmolality of AC6-deficient mice to the levels of wild-t

201 nditions found within the host, including an osmolality of approximately 290 mosmol kg(-1).

202 c saline therapy maintained to achieve serum osmolality of approximately 350 mOsm/L is beneficial for

203 he ECS by changing the NaCl content to alter osmolality of bathing media for rat cortical slices.

204 brain plays a pivotal role in regulating the osmolality of body fluids.

205 on through PDMS and associated shifts in the osmolality of culture media was significant and prevente

206 asmic, and periplasmic water as functions of osmolality of growth and osmolality of plasmolysis of no

207 ic players in the ageing process, and affect osmolality of growth media in stationary phase cultures.

208 ctivity of Escherichia coli as a function of osmolality of growth, we have quantified and analyzed am

209 The osmolality of plasma was measured by using freezing poin

210 ter as functions of osmolality of growth and osmolality of plasmolysis of nongrowing cells with NaCl.

211 The sodium content, chloride activity and osmolality of saliva in Nhe2(-/-) or Nhe3(-/-) mice were

212 ls and quantified the response to changes in osmolality of the bathing solution.

213 t of NaCl was excluded by the following: (a) osmolality of the collected fluid remained unchanged and

214 identify genes affected by the environmental osmolality of the culture medium.

215 s the same maximal level irrespective of the osmolality of the media.

216 privation, a condition known to increase the osmolality of the medulla.

217 e binding site decreases with the increasing osmolality of the solution, resulting in acquisition of

218 dextrose, desmopressin does not increase the osmolality of the urine in -/- mice (624 +/- 19 to 656 +

219 The effect of changes in osmolality on nuclear morphology (p < 0.01) and chromati

220 ntrations were higher in samples with raised osmolality or copeptin (a surrogate marker for AVP).

221 plasma AVP concentration ([AVP]P) vs. urine osmolality (OsmU) were fitted to a sigmoidal curve, and

222 Total water intake (P = 0.002), urine osmolality (P < 0.001), and hypohydration prevalence (P

223 and polyuria (P < 0.04), with a lower urine osmolality (P < 0.003) as compared to Nhe3+/+ mice.

224 8%) had higher glucose (P < 0.001) and serum osmolality (P < 0.01).

225 njection (P = 0.03), and increased tear film osmolality (P = 0.05).

226 However, only plasma osmolality (P(osm)) showed statistical promise for use i

227 vity of a hog1 null mutant in which the high osmolality pathway is disrupted.

228 variety of tear film (e.g., interferometry, osmolality, phenol red thread, meibography, fluorescein,

229 ese results with ongoing behavior and plasma osmolality points to the existence of brain networks tha

230 a sodium (WD(5)), the substitution of plasma osmolality (Posm) for sodium (WD(6)), and actual Posm (W

231 ividuals classified as DE have higher plasma osmolality (Posm), indicating suboptimal hydration, comp

232 rap regression provides a unique insight for osmolality prediction equation performance from a very l

233 mperature shift, serum starvation, increased osmolality, reactive oxygen intermediates, and increased

234 mising equations were examined against serum osmolality (reference standard).

235 Serum osmolality, regional brain water content, blood-brain ba

236 mouse corneal preparation demonstrated that osmolality regulated the electrical activity of TRPM8-ex

237 iverse functions ranging from nociception to osmolality regulation.

238 and urine flow and a reduced maximal urinary osmolality relative to wild-type controls.

239 urine during 24-h water restriction, urinary osmolality remained significantly lower than in WT mice,

240 After recovery, and if the external osmolality remains high, cells have been shown to grow m

241 ous work established that plasma [Na(+)] and osmolality rise in proportion with salt intake and thus

242 ltant "permissive hypercapnia." Lactates and osmolalities rose on initiation and fell, as expected, o

243 armacokinetics, did not affect urine output, osmolality, salt excretion, or acid-base balance.

244 notype is the consequence of decreased urine osmolality secondary to renal vasopressin resistance.

245 nally, we identify a hormone receptor and an osmolality-sensitive ion channel that underlie this regu

246 , solute and urea excretion, serum and urine osmolality, serum creatinine, 24-h creatinine clearance,

247 Evaporation-mediated osmolality shifts through PDMS membranes with varying th

248 oped that greatly suppresses evaporation and osmolality shifts, yet possesses thinness and the flexib

249 0-9 m2/s, accounts for these evaporation and osmolality shifts.

250 tively, the data indicate that extracellular osmolality stimulates receptor activity and receptor gen

251 defect at high temperature in media of high osmolality suggested that this disaccharide is crucial f

252 ut there was a significant increase of urine osmolality, suggesting that DI may be caused by a defect

253 65) in WT mice elicited an increase in urine osmolality, suggesting that LXRbeta is a key receptor in

254 serine-256 and serine-269), and lower urine osmolality than wild-type mice.

255 asing external psi through increases in cell osmolality that were accomplished by increased solute lo

256 Reducing osmolality to 150 mosmol kg(-1), increased lambda to 1.8

257 produced a physiological increase in plasma osmolality to 299 +/- 1 mosmol (kg water)(-1), elicited

258 Increasing osmolality to 350 mosmol kg(-1), reduced lambda to about

259 An increase in osmolality to 550 milliosmoles per kg of water (mosmol/k

260 nes are activated during increases in plasma osmolality to elicit sympathoexcitation.

261 was accelerated by a return of extracellular osmolality to isosmotic levels.

262 unctionally adapt to changes of interstitial osmolality/tonicity.

263 Bilateral reduction in osmolality transiently increased short-circuit current (

264 Low [Na(+)], rather than low osmolality, triggered these effects.

265 copeptin concentrations independent of serum osmolality (type A); 14% had copeptin concentrations tha

266 ormal copeptin concentrations independent of osmolality (type C), and 12% had suppressed copeptin con

267 essed copeptin concentrations independent of osmolality (type D).

268 opeptin concentrations with increasing serum osmolality (type E or "barostat reset").

269 on with depth results in increasing internal osmolality (typically 350 mOsmol/kg in shallow species c

270 n UT-B- deficient mice (p < 0.01), and urine osmolality (U(osm)) was lower (1532 +/- 71 versus 2056 +

271 ess biomarkers excreted in urine and urinary osmolality (Uosm).

272 At moderate growth osmolalities (up to 1 Osm), we conclude that GB is an ef

273 index tests included USG, urine color, urine osmolality, urine cloudiness, additional dipstick measur

274 output and fluid intake, and increases urine osmolality, urine sodium concentration, and plasma AVP l

275 further differentiated on the basis of urine osmolality, urine sodium level, and volume status.

276 medulla for cellular protection against high osmolality via organic osmolytes and molecular chaperone

277 The relationship between condensation and osmolality was accurately modeled by a polymer gel model

278 Serum sodium was measured, serum osmolality was calculated, and echocardiograms and chest

279 papillary interstitium), the collected fluid osmolality was decreased significantly below that of the

280 Serum osmolality was determined at the end of the experiment i

281 Serum osmolality was determined at the end of the experiment i

282 Urine osmolality was determined with the use of freezing-point

283 The decrease in osmolality was due to greater efflux of NaCl as compared

284 pacity: Urine flow rate was higher and urine osmolality was lower than control rats despite an increa

285 Serum osmolality was measured by using freezing point depressi

286 inst a 600 mosmol/liter bath in which 50% of osmolality was NaCl and 50% urea (to simulate in vivo pa

287 rats injected with lipopolysaccharide, urine osmolality was reduced by ~40%, along with medullary ind

288 In states of elevated osmolality, water availability rapidly decreased VPpp ne

289 Nonetheless, urinary osmolalities were similar in mPges1(+/+) and mPges1(-/-)

290 olic cages and their water balance and urine osmolality were examined.

291 atio were observed when either creatinine or osmolality were used to standardize or as covariates.

292 fferent equations used for predicting plasma osmolality when its direct measurement was not practical

293 tions appeared optimal for the prediction of osmolality when its direct measurement was not practical

294 ProP attains the same activity at the same osmolality when the medium outside cells or proteoliposo

295 At very high growth osmolalities where cells contain little cytoplasmic wate

296 ur over a very narrow range of physiological osmolalities, which suggests that chondrocytes likely ex

297 impairment in their water balance and urine osmolality, which correlates with the downregulation of

298 e association between water intake and urine osmolality, which is a hydration biomarker, varied by we

299 We assessed the agreement of measured serum osmolality with calculated serum osmolarity equations in

300 However, similar elevation of osmolality with urea did not increase p53 levels.

301 agreement and the capacity to predict serum osmolality within 2% in >80% of participants, regardless

302 the hypothesis that the unique extracellular osmolality within the renal medulla modulates a specific

303 roP activity at high osmolality, but not the osmolality, yielding half-maximal activity (Pi(1/2)/RT),