ライフサイエンスコーパス: osmotically

1 The system was shown to be both osmotically activated and cryoactivated.

2 DNAs encoding the vanilloid receptor-related osmotically activated channel (VR-OAC) from the rat, mou

3 previously named vanilloid receptor-related osmotically activated channel (VR-OAC), functions in viv

4 Dialysis with phalloidin also prevented hypo-osmotically activated Cl- currents.

5 channel, vanilloid subfamily (TRPV4), is an osmotically activated ion channel that is expressed in c

6 Thus, in addition to defining a novel osmotically activated signal transduction pathway in B c

7 he expression of IEGs and vasopressin in the osmotically activated SON in vivo.

8 arance would increase after inhalation of an osmotically active agent that would increase the volume

9 is observed in the presence of a variety of osmotically active compounds indicating that Em protein

10 lity (Boyle van't Hoff relationship) with an osmotically active intracellular water fraction of 61%.

11 hanges are aided by the concerted release of osmotically active ions, most notably K(+) and Cl(-).

12 de that oxalate acts via (1) accumulation of osmotically active molecules to induce stomatal opening

13 h transported L-alanine via system B into an osmotically active space energized by secondary active t

14 ake of L-tryptophan is substantially into an osmotically active space.

15 mine if plants can up-regulate the efflux of osmotically active substances into embolized vessels and

16 d that reovirus-induced lysis of RBCs occurs osmotically, after formation of small size-selective les

17 solutions included control Tyrode's (1T) and osmotically altered Tyrode's (2.6T, 0.9T, and 0.6T) solu

18 nts at the apical, mid, and basal regions of osmotically and electrically stimulated cells.

19 TonEBP/OREBP contain a TAD that is regulated osmotically, apparently by tonicity-dependent phosphoryl

20 is phenotype could be repressed by growth on osmotically buffered medium at low temperature.

21 , but IPSCs, evoked by local stimulation, or osmotically by hypertonic sucrose application, were dimi

22 The LSL-mediated hemolysis was protected osmotically by polyethylene glycol 4000 and maltohexaose

23 Hyaluronan has the greater effect, acting osmotically by way of a concentration polarization bound

24 HeLa cells and U2-OS osteosarcoma cells were osmotically challenged with 100-200 mm sorbitol, and the

25 The fixed stromal charge of bovine corneas, osmotically clamped at physiological hydration, was alte

26 to compare the lattice spacing of dissected, osmotically compressed skinned fibers to native muscle f

27 interesting possibility of dimerization when osmotically compressed to high densities while undergoin

28 med additional experiments on skinned strips osmotically compressed to the intact lattice spacing as

29 are platelets, produced lithographically, is osmotically concentrated in a flat plane to raise the pa

30 First we use a fluorescence assay to track osmotically controlled membrane deformation in single co

31 to the less-dense cholesteric phase through osmotically controlled swelling shows the loss of this b

32 The size of these tubes is osmotically controlled using dialysis, which makes them

33 er resulted in a significant increase in the osmotically directed net fluid secretion rate across mon

34 Inhaled hypertonic saline osmotically draws water onto airway surfaces, improves m

35 Enhanced movement of cations may osmotically drive water entry, resulting in balloon dege

36 vide additional support for the concept that osmotically driven and agonist-stimulated water movement

37 Potassium flux causes osmotically driven changes in guard cell volume that reg

38 Although these movements are governed by osmotically driven changes in guard cell volume, the rol

39 these amphiphiles grew spontaneously through osmotically driven competition between vesicles, and fur

40 The process of osmotically driven crystal morphogenesis of polyoxometal

41 Further, we utilize osmotically driven emulsification to tailor the structur

42 The osmotically driven ingress of water leads to an increase

43 Despite their role in osmotically driven lung water transport, aquaporins are

44 Conversely, osmotically driven magnocellular neurosecretory neuronal

45 Osmotically driven membrane processes (including forward

46 Osmotically driven membrane processes (ODMP) have gained

47 solute interactions can affect the design of osmotically driven membrane processes (ODMPs) is critica

48 ed in five additional rabbits implanted with osmotically driven minipumps containing endothelin-1 (0.

49 ural region of the anterior optic nerve with osmotically driven minipumps.

50 e central nervous system and facilitates the osmotically driven pathological brain swelling associate

51 source, thereby providing new support for an osmotically driven refilling mechanism.

52 Based on previous findings, we combine osmotically driven shape oscillations with tissue mechan

53 lism, we found that it did not supervise the osmotically driven switch in the biological activities o

54 use molecular dynamics simulations to study osmotically driven transport of water molecules through

55 We discuss the implications of this osmotically driven type of surface motility for nutrient

56 k this limitation by taking advantage of the osmotically driven water flux between a droplet containi

57 um rate of 0.11% s(-1) Analyzing swelling as osmotically driven water influx, we find the H2O membran

58 water-transporting proteins that facilitate osmotically driven water movement across cell plasma mem

59 ) water channels provide a major pathway for osmotically driven water movement across epithelial and

60 sults establish a novel method for measuring osmotically driven water permeability across microvessel

61 f AQP1 in OMDVR water transport, we measured osmotically driven water permeability in vitro in microp

62 These results indicate that osmotically driven water transport across microvessels i

63 nt in mucus clearance, whereas inhibition of osmotically driven water transport by amiloride accounte

64 way epithelium coexists and is distinct from osmotically driven water transport.

65 in alpha-hemolysin (alphaHL), to demonstrate osmotically-driven mass transfer of fluid across surfact

66 the lumen of the colon, which is followed by osmotically-driven water absorption, so we hypothesized

67 nce of septation when grown on a traditional osmotically enhanced medium.

68 les is expected when pores are formed in the osmotically equilibrated membranes, our results support

69 critical for normal fluid balance, mediating osmotically evoked drinking and neurohypophysial hormone

70 e predictions of this model, we find that an osmotically expanding hydrogel responds to step changes

71 Water osmotically follows the release of Cl(-) through ion cha

72 Sodium lactate was substituted iso-osmotically for sodium chloride.

73 tion were viable with mildly spherocytic and osmotically fragile erythrocytes.

74 The headpiece null erythrocytes were osmotically fragile, and ektacytometry/micropore filtrat

75 beta-adducin null RBCs are osmotically fragile, spherocytic, and dehydrated compare

76 bstructions, and phloem flow is driven by an osmotically generated pressure differential according to

77 ted that flow of assimilates is driven by an osmotically generated pressure differential, as proposed

78 Ernst Munch in 1930 describes a mechanism of osmotically generated pressure differentials that are su

79 p is driven through phloem sieve tubes by an osmotically generated pressure gradient between source a

80 anced, finite-difference solution to Munch's osmotically generated pressure-flow hypothesis is develo

81 ungus requires and utilizes melanin-derived, osmotically generated pressures estimated at 80 bars to

82 The amplitude of the osmotically induced [Ca(2+)](cyt) transient was attenuat

83 hanisms must exist that discriminate between osmotically induced and other forms of stress-induced pr

84 ncentrations (< 55 mM) and a second that was osmotically induced at high concentrations (> 55 mM) and

85 Osmotically induced budding of the ATPS-containing GVs l

86 F is released by cultured ECs in response to osmotically induced cell injury.

87 Entpd3), restricts the range and duration of osmotically induced cell migration after injury.

88 Osmotically induced cell swelling and subsequent regulat

89 s suppressed, increasing membrane tension by osmotically induced cell swelling increased FM1-43 fluor

90 We report that osmotically induced cell volume changes, which are known

91 media and inhibited in hypertonic media; the osmotically induced changes in activity occurred within

92 2+) and Ca(2+) influx were also sensitive to osmotically induced changes in cell volume.

93 We conclude that TRPM7 senses osmotically induced changes primarily through molecular

94 The osmotically induced decrease in ER-beta expression was s

95 sing transporter ProP protects bacteria from osmotically induced dehydration by mediating the uptake

96 o a universal reduction in the expression of osmotically induced genes.

97 Activation of AT1R subtype a by osmotically induced membrane stretch suppresses an XE991

98 t TRPC6 is also a sensor of mechanically and osmotically induced membrane stretch.

99 rginine decarboxylase) responsible for their osmotically induced putrescine accumulation.

100 Analyses of osmotically induced release as well as Ca2+ triggered an

101 The results support the view that the osmotically induced rise in putrescine and blockage of i

102 The yeast TRPY1 is activated in vivo by osmotically induced vacuolar membrane deformation and by

103 Here we analyze osmotically induced vacuole fragmentation by time-lapse

104 rt describes the influence of fluid flow and osmotically induced volume changes on Na(+)-Ca(2+) excha

105 ivity is modulated by both solution flow and osmotically induced volume changes.

106 parietal and visceral tissues are sources of osmotically induced water flow into the cavity.

107 Osmotically induced water transport was rapid in choroid

108 r weight, ester end-capped PLGA displayed an osmotically induced/pore diffusion mechanism based on co

109 data confirm and extend previous reports of osmotically-induced FLI in rat brain and demonstrate tha

110 The level of osmotically-induced TRPV4 activation, although proportio

111 Thus, the SFO is important for the osmotically-induced water drinking response after acute

112 ized, putative AlgU promoter upstream of the osmotically inducible gene osmE.

113 In Saccharomyces cerevisiae, many osmotically inducible genes are regulated by the Sko1p-S

114 pression of a number of stationary-phase and osmotically inducible genes in enteric bacteria.

115 pression of a number of stationary-phase and osmotically inducible genes in Escherichia coli.

116 rane and periplasmic proteins, including the osmotically inducible genes osmB and osmC.

117 sitive and display compromised expression of osmotically inducible genes.

118 Although most of the genes of the osmotically inducible regulon were overexpressed in medi

119 All three genes are osmotically inducible to some degree.

120 membrane, and functions as a vehicle for the osmotically inert storage of a variety of granule-bound

121 ions of the impermeable solute sucrose, they osmotically lose ~85% of their cellular water in less th

122 e layered, in a centrifuge chamber, above an osmotically matched dense solution, containing Nycodenz,

123 Importantly, when the swelling rate was osmotically matched for AQP4-positive and AQP4-negative

124 /GSH, and NAD+/NADH and fails to prevent the osmotically mediated depletion of GSH and taurine and th

125 are not absorbed in the colon and induce an osmotically mediated diarrhea; in contrast, SCFA are abs

126 1) the osmotically most sensitive and 2) the osmotically most resistant erythrocyte membranes in an a

127 rocedure to isolate subpopulations of 1) the osmotically most sensitive and 2) the osmotically most r

128 These solutes are acting osmotically on the condensed array.

129 ir growth and division takes place within an osmotically protected environment, and also due to a dri

130 vely within the interior of living cells, an osmotically protected niche.

131 cally require growth for many generations on osmotically protective media with antibiotics or enzymes

132 t (a) there was transport of Gly-Gln into an osmotically reactive space inside the lysosomal membrane

133 -site mutation, additional controls exist to osmotically regulate P1 expression.

134 hyperosmotic stress during infection because osmotically regulated genes were highly induced inside p

135 ated with increased transcription of several osmotically regulated genes.

136 o ~15-copy-number-stabilized pGA1 behind the osmotically regulated ompC promoter, resulting in high e

137 Unlike most other osmotically regulated promoters, the induction occurs fo

138 In contrast to observations in some other osmotically regulated systems, addition of glycine betai

139 thesis of the osmoprotectant glycerol and is osmotically regulated via the high osmolarity glycerol (

140 1, was transcribed and its transcription was osmotically regulated.

141 day of atomoxetine (N=222), 18-54 mg/day of osmotically released methylphenidate (N=220), or placebo

142 Response was significantly greater with osmotically released methylphenidate than with atomoxeti

143 that for placebo (24%), but the response to osmotically released methylphenidate was superior to tha

144 ecrease in ADHD Rating Scale total score) to osmotically released methylphenidate with response to at

145 d to atomoxetine had previously responded to osmotically released methylphenidate.

146 eter expansions in fusions of membranes from osmotically resistant erythrocytes are faster in the ear

147 rged spheres, so that one mutant synthesized osmotically resistant peptidoglycan when only 2 of 12 PB

148 pneumophila was sodium sensitive, cytotoxic, osmotically resistant, competent to evade macrophage lys

149 riant RING finger protein high expression of osmotically responsive gene (HOS)1 was identified geneti

150 E3-ubiquitin ligase rice HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENE1 (OsHOS1), which mediates pr

151 ere, we demonstrated that HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES 1 (HOS1), which is known to

152 sive genes), and hos (for high expression of osmotically responsive genes) mutants were identified by

153 esponsive genes), los (for low expression of osmotically responsive genes), and hos (for high express

154 psis mutant, hos10-1 (for high expression of osmotically responsive genes), in which the expression o

155 of a mutant, hos9-1 (for high expression of osmotically responsive genes), in which the reporter con

156 umber of cos (for constitutive expression of osmotically responsive genes), los (for low expression o

157 Here we report that High Expression Of Osmotically Responsive Genes1 (HOS1) is a regulator of a

158 caused by a lesion in the high expression of osmotically responsive genes1 (HOS1) locus, which encode

159 t the E3 ubiquitin ligase HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES1 (HOS1) physically interact

160 y the E3 ubiquitin ligase HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES1 (HOS1).

161 ted DEAD box RNA helicase (LOW EXPRESSION OF OSMOTICALLY RESPONSIVE GENES4 [LOS4]) that regulates mRN

162 We find similar behavior in the osmotically responsive HOG pathway.

163 ransport into HL60/ADR membrane vesicles was osmotically sensitive and dependent on ATP concentration

164 Drug transport was osmotically sensitive and saturable with regard to drug

165 Drug uptake was osmotically sensitive and saturable with regard to subst

166 As(GS)(3) transport by MRP1 was osmotically sensitive and was inhibited by several conju

167 ded probes and can in principle apply to any osmotically sensitive bioactivity, opening new routes fo

168 d the unusual property of accumulating in an osmotically sensitive cellular compartment of Escherichi

169 v) leaderless DsbA was not transported to an osmotically sensitive compartment via a secA- or ftsZ-de

170 r proton ATPase, responded to changes in the osmotically sensitive intravesicular space, and was satu

171 ggesting the presence of a sodium-conducting osmotically sensitive ion channel.

172 also find evidence that a sodium-conducting osmotically sensitive mechanism contributes to salt resp

173 xpand as far as in fusions of membranes from osmotically sensitive membranes.

174 after bile duct ligation and is regulated by osmotically sensitive miRs.

175 We show that CRP-cAMP functions as an osmotically sensitive repressor of proP P1 transcription

176 -dependent transport in SMP occurred into an osmotically sensitive space and was inhibited by the ant

177 Choline uptake into an osmotically sensitive space was not stimulated by an out

178 le (Km = 62 micromol/L) and occurred into an osmotically sensitive space.

179 the membrane protein thought to mediate the osmotically sensitive taurine efflux.

180 icles show that MRP1 supports ATP-dependent, osmotically sensitive uptake of MX.

181 Furthermore, mutant embryos are osmotically sensitive, allowing us to designate this gen

182 pI::cm mutation rendered growth of the cells osmotically sensitive, and incubation of the insertion m

183 port of MTX into vesicles was ATP-dependent, osmotically sensitive, and inhibited by fumitremorgin C.

184 ly conserved stress-activated p38-type MAPK [Osmotically Sensitive-2 (OS-2)] by the N. crassa circadi

185 whereas Fis and Lac repressor binding is not osmotically sensitive.

186 To influence water flow, we osmotically shock the cell during cell division, and fin

187 icroscopic assessments of tubular changes in osmotically shocked and control fibres from frog sartori

188 Yet, cells that had been osmotically shocked and treated with paraformaldehyde we

189 Using osmotically shocked cells for protease treatments, the N

190 Electron micrographs of osmotically shocked cells showed a significant decrease

191 endent glycolate or P-glycolate oxidation by osmotically shocked chloroplasts from the algae Dunaliel

192 When crude extracts of French-pressed or osmotically shocked Escherichia coli cells are centrifug

193 otentials from cooled, superficial fibres in osmotically shocked muscles lacked after-depolarization

194 This finding indicates that in osmotically shocked or electroporated bacteria, proteins

195 ly, when keratinocytes are stretched or hypo-osmotically shocked, alpha6beta4 integrin accumulates at

196 erioplankton may actively accumulate DMSP to osmotically significant concentrations that favor near-m

197 Pores that were opened in osmotically stabilized erythrocytes could not be closed

198 mediated shRNA knockdown of Caprin-2 in the osmotically stimulated hypothalamus shortens the AVP mRN

199 h low plasma membrane PtdInsP(2) levels were osmotically stimulated, a mild osmotic stress (12.5 mM K

200 also used a range of NaCl concentrations to osmotically stress the rbc's.

201 a primary determinant of the growth rate of osmotically stressed cells.

202 e precipitated by GST-Ssk2p from extracts of osmotically stressed cells.

203 nt with regulation of JNK-1 by p38 kinase in osmotically stressed cells.

204 th up-regulation of native JNK-1 activity in osmotically stressed cells.

205 k but localizes to cortical actin patches in osmotically stressed cells.

206 ne decarboxylase activities decline in these osmotically stressed dicot leaves, while spermidine and

207 and macromolecular crowding in the growth of osmotically stressed Escherichia coli, we have determine

208 nopurification of overexpressed PPIP5K1 from osmotically stressed HEK cells (0.2 M sorbitol; 30 min)

209 response was observed between TNF-alpha and osmotically stressed human liver cells.

210 Osmotically stressed leaves showed increased peak IV kin

211 X-ray diffraction analysis of osmotically stressed LPS multilayers was used to determi

212 nsporter 1 and heat shock protein 70 mRNA in osmotically stressed MDCK cells, blocks cell proliferati

213 inases (MSTs) (members of the Pak family) in osmotically stressed neutrophils and neutrophils treated

214 Inhibiting JNK2 production by siRNA in osmotically stressed PCHCE cells prevented the stimulati

215 Ins(1,4,5)P(3) accumulate in salt, cold, and osmotically stressed plants.

216 2p, and complement actin recovery defects in osmotically stressed ssk2delta and spa2delta yeast cells

217 f the TNFalpha and lymphotoxin-beta genes in osmotically stressed T cells.

218 ton recovery to the neck of late cell cycle, osmotically stressed yeast cells.

219 citance were observed when the cultures were osmotically stretched.

220 By osmotically suppressing DNA release from HSV-1 capsids,

221 sely, when membrane tension was increased by osmotically swelling cells, the extension rate decreased

222 n reveals an unusual structure consisting of osmotically swollen stacks of composite membranes with n

223 cture of BtuB in its holo form represents an osmotically trapped conformation.

224 f macrophages and lymphocytes, which present osmotically variable environments, and hydration-depende

225 lmost universally believed), or because they osmotically withdraw a large fraction of intracellular w