ライフサイエンスコーパス: osteoblast-like

1 growth factor treatment or with the state of osteoblast-like activity and appears to determine the na

2 The identification of osteoblast-like and osteoclast-like cells in human tissu

3 Sp3 sites act as enhancers in both MC3T3-E1 (osteoblast-like) and J774 (macrophage-like) cell lines,

4 These include the presence of osteoblast-like calcifying vascular cells in the artery

5 We have demonstrated that both the UMR-106 osteoblast-like cell line and human osteoblasts in prima

6 bone formation within osteoblasts and in the osteoblast-like cell line MC3T3-E1, a finding consistent

7 In the human osteoblast-like cell line MG-63, 1,25-(OH)(2)D(3) and 19

8 estosterone with calcium channels in the rat osteoblast-like cell line ROS 17/2.8 was investigated.

9 Three different human osteoblast-like cell lines (MG-63, HOS, and SaOS-2) and

10 Osteoblast-like cell lines 2T3 and Oct-1 also show incre

11 well as murine (MC3T3-E1) and human (MG-63) osteoblast-like cell lines displayed all the previously

12 element that drives human SOST expression in osteoblast-like cell lines in vitro and in the skeletal

13 steocalcin expression, we used rat and human osteoblast-like cell lines to generate stably transfecte

14 , whose expression is controlled by CBFA1 in osteoblast-like cell lines.

15 with inflammatory changes and expression of osteoblast-like cell phenotypes, but the cellular mechan

16 muscle cells to change into a chondrocyte or osteoblast-like cell; high total body burden of calcium

17 tion, RANKL upregulation in human mandibular osteoblast-like cells (HMOBs) were stimulated with PGE2.

18 simple, reproducible method to isolate human osteoblast-like cells (HOBs) and to evaluate in vitro ce

19 y was to examine the expression of CaMKII in osteoblast-like cells (MC4) and to elucidate its role in

20 nesis, nonosseous calcification, and ectopic osteoblast-like cells (that appear to function different

21 and cultured with fetal calf serum (10% for osteoblast-like cells and 2% for osteoclast-like cells).

22 anism of action of applied tensile forces in osteoblast-like cells and have critical implications in

23 The promoters are active in both osteoblast-like cells and in the M12 B-lymphocyte cell l

24 ation of the balance between the activity of osteoblast-like cells and OLCs.

25 In the present study MG63 osteoblast-like cells and primary bone marrow stromal ce

26 ot analysis, we have demonstrated that human osteoblast-like cells as well as primary human osteoblas

27 is verified the differentiation of DFCs into osteoblast-like cells because clusters of mineralization

28 target gene expression were up-regulated in osteoblast-like cells derived from cortical bone of fema

29 ng vascular cells (CVCs), a subpopulation of osteoblast-like cells derived from the artery wall, were

30 ate that Gli1(+) cells are a major source of osteoblast-like cells during calcification in the media

31 These osteoblast-like cells from ALSKO mice failed to induce o

32 ADAM19 is also highly expressed in osteoblast-like cells in the bone, yet it does not appea

33 ted in the present study using UMR106-01 rat osteoblast-like cells in vitro.

34 at [Ca2+]o-stimulated chemotaxis of MC3T3-E1 osteoblast-like cells involves a G-protein-linked calciu

35 of the murine osteocyte cell line MLO-Y4 and osteoblast-like cells MC3T3-E1 and in primary rat osteob

36 ses of primary mouse osteoblasts and UMR-106 osteoblast-like cells to a single period of dynamic stra

37 MG63 osteoblast-like cells were cultured on the 3 different s

38 Stably alpha2-silenced MG63 human osteoblast-like cells were used to test whether alpha2be

39 only been shown in some, but not all, clonal osteoblast-like cells, and the molecular mechanisms unde

40 AK can target human primary chondrocytes and osteoblast-like cells, in addition to synovial fibroblas

41 al stress and selective differentiation into osteoblast-like cells, offering a promising nanotechnolo

42 sed by stimulation of proliferation of MG-63 osteoblast-like cells, was used to monitor purification

43 human and mouse osteoblasts and mouse MC3T3 osteoblast-like cells, we found that Akt activation by F

44 tiation of vascular smooth muscle cells into osteoblast-like cells, we investigated whether miRs impl

45 ansforming vascular smooth muscle cells into osteoblast-like cells, which can produce a matrix of bon

46 e beta(5) gene expression in macrophages and osteoblast-like cells, with each element exhibiting cell

47 tometry validated the target specifically in osteoblast-like cells.

48 organized extracellular matrix deposition by osteoblast-like cells.

49 in human microvascular endothelial and human osteoblast-like cells.

50 oses of PTH attenuated P(1)/P(2) activity in osteoblast-like cells.

51 uent transdifferentiation of PAH-PASMCs into osteoblast-like cells.

52 ma cells and in adhesion of myeloma cells to osteoblast-like cells.

53 s of MEK(SP) were specific to Cbfa1-positive osteoblast-like cells.

54 n macrophage (osteoclast precursor)-like and osteoblast-like cells.

55 with TGF-beta 1, PDGF-BB, and bFGF in bovine osteoblast-like cells.

56 PTH-stimulated adenylyl cyclase activity in osteoblast-like cells.

57 tive stress, uremia, and hyperphosphatemia, "osteoblast-like" cells form in the vessel wall.

58 cultures resulted in reacquisition of their osteoblast-like characteristics and lack of LPS responsi

59 l significance of the loss of the PDL cell's osteoblast-like characteristics during inflammation.

60 we observed that IL-1beta down-regulates the osteoblast-like characteristics of PDL cells in vitro.

61 th IL-1beta inhibits the expression of their osteoblast-like characteristics, as assessed by the fail

62 orskolin treatment of CVC for 3 days induced osteoblast-like "cuboidal" morphology, inhibited prolife

63 In MC3T3-E1 osteoblast-like cultures, dexamethasone (DEX) activates

64 in vitro vascular calcification by enhancing osteoblast-like differentiation of CVC.

65 nesis in PDL cells while down-regulating its osteoblast-like features and simultaneously reducing the

66 ed the levels of p21 mRNA and protein in the osteoblast-like human osteosarcoma cell line MG63 and st

67 ted gene transcription and mineralization in osteoblast-like MC3T3-E1 cells (WT) via a mechanism invo

68 Immunocytochemical studies performed with osteoblast-like MC3T3-E1 cells and other mammalian cell

69 Osteoblast-like MC3T3-E1 cells were allowed to attach to

70 have found that a lipid fraction from human osteoblast-like MG63 cell-conditioned medium (MG63CM) co

71 r cells with TNF-alpha for 3 days induced an osteoblast-like morphology.

72 We show here that differentiated osteoblasts, like neurons, express the norepinephrine tr

73 , the MC3T3-E1(MC3T3) pre-osteoblast and rat osteoblast-like osteosarcoma 17/2.8 cell.

74 The fully differentiated rat osteoblast-like osteosarcoma 17/2.8 cells responded rapi

75 morphogenetic protein-2 [BMP-2]), MG63 human osteoblast-like osteosarcoma cells, and normal human ost

76 ulture undergo a phenotypic conversion to an osteoblast-like pattern of gene expression.

77 e profiles in three separate clones of human osteoblast-like PDL cells.

78 ed at the interface of bone and teeth, where osteoblast-like periodontal ligament (PDL) cells constan

79 a healthy periodontium PDL cells exhibit an osteoblast-like phenotype and are unresponsive to gram-n

80 -Luc assay in HepG2 cells as well as induced osteoblast-like phenotype in C2C12 cells expressing alka

81 Cells exhibiting an osteoblast-like phenotype in the vessel wall may be impo

82 Furthermore, TGF-beta1 down-regulated the osteoblast-like phenotype of PDL cells, i.e., alkaline p

83 lve associated with the transformation to an osteoblast-like phenotype that is inhibited by atorvasta

84 An osteoblast-like phenotype was in part verified for these

85 mal fibroblasts lacking Smad3 can acquire an osteoblast-like phenotype, including activation of Runx2

86 f vascular smooth muscle cells (VSMCs) to an osteoblast-like phenotype.

87 ence on differentiation of the cells into an osteoblast-like phenotype.

88 tion and that this process is mediated by an osteoblast-like phenotype.

89 active regulated process associated with an osteoblast-like phenotype.

90 To further determine the osteoblast-like properties of PDL cells, human PDL cells

91 TGF-L inhibits osteocalcin production in rat osteoblast-like Ros 17/2.8 cells.

92 receptor-mediated increases in ECAR in human osteoblast-like SaOS-2 cells.

93 vity of stretch-activated cation channels of osteoblast-like UMR-106.01 cells.

94 F)-alpha-induced NF-kappaB activation in rat osteoblast-like UMR106 cells.