ライフサイエンスコーパス: osteoclast number

1 is no systemic inflammation and no change in osteoclast number.

2 itis via impacting synovial inflammation and osteoclast number.

3 in osteopenia associated with an increase in osteoclast number.

4 vivo increased calvarial vessel density and osteoclast number.

5 of bone cancer with only a modest effect on osteoclast number.

6 ot affect osteoblast apoptosis but increases osteoclast number.

7 ation rate, and bone mass, but do not affect osteoclast number.

8 ) mice, correlating with the increase in the osteoclast number.

9 ring properties and its capacity to decrease osteoclast number.

10 y, reduced osteoblast numbers, and increased osteoclast numbers.

11 ion, but with parallel notable reductions in osteoclast numbers.

12 iosteoclastic activity, and the reduction in osteoclast numbers.

13 also causes high bone mass due to decreased osteoclast numbers.

14 l molecule ERK5 pathway inhibitors increased osteoclast numbers.

15 honates suppress osteoclast activity but not osteoclast numbers.

16 e is accompanied by a pronounced increase in osteoclast numbers, although Smurf2-deficient osteoclast

17 ficiency triggers a drastic increase in both osteoclast number and activity (hyper-activation), mecha

18 bone metastases are characterized by excess osteoclast number and activity.

19 e had mild osteopetrosis caused by decreased osteoclast number and bone resorption.

20 This was followed by a decrease in osteoclast number and eroded surface, which was associat

21 ine decreases bone loss through reduction of osteoclast number and induces reduction of IL-6, MMP-1,

22 ll mice, this was followed by an increase in osteoclast number and normalization of bone volume.

23 signaling suppressed, rather than enhanced, osteoclast number and osteoclast surface as well as urin

24 umber and osteoblast activity with unaltered osteoclast number and osteoclast surface in knockout ani

25 orption as demonstrated in vivo by increased osteoclast number and serum C-terminal telopeptides, a m

26 Osteoclast number and surface are significantly lower in

27 calcin; but increased trabecular separation, osteoclast number and surface, and RANKL expression.

28 s; however, no correlation was found between osteoclast number and the amount of resorption.

29 etric analysis was performed to quantify the osteoclast number and the area of bone resorption.

30 teocytes were protected from the increase in osteoclast number and the bone loss caused by ovariectom

31 Lack of MMP-9 decreased osteoclast numbers and abrogated angiogenesis in respons

32 This change coincided with elevated osteoclast numbers and accelerated removal of cartilage

33 pe 2 diabetic group had significantly higher osteoclast numbers and activity (P < 0.05).

34 While osteoclast numbers and activity are regulated by osteopr

35 Castration greatly increases osteoclast numbers and activity in GRKO mice and promote

36 in fXIIIA(-/-) mice concurrent with reduced osteoclast numbers and activity.

37 -/-) mice, although having normal basal bone osteoclast numbers and bone density, are resistant to ph

38 ing as evidenced by decreased osteoblast and osteoclast numbers and decreased bone formation rate; as

39 from mu-calpain(-/-) mice revealed increased osteoclast numbers and decreased trabecular bone volume

40 Furthermore, osteoclast numbers and expression of osteoclast marker g

41 Increased osteoclast numbers and increased eroded surface areas su

42 s of Ank (KI/KI) incisors revealed decreased osteoclast numbers and osteoclast surfaces.

43 ce expressing p62(P392L) developed increased osteoclast numbers and progressive bone loss, but osteob

44 eopenic phenotype characterized by increased osteoclast numbers and surface, which are normalized in

45 as abrogated, as evidenced by maintenance of osteoclast numbers and, additionally, loss of bone densi

46 clodronate and AppCCl2p on bone resorption, osteoclast number, and apoptosis in vitro were compared.

47 ed with osteoclast differentiation, enhanced osteoclast number, and bone matrix degradation.

48 greater periodontal ligament surface, higher osteoclast number, and greater lamina dura apposition wi

49 Periodontal tissue destruction, osteoclast number, and inflammation were assessed by his

50 tor activator of NF-kappaB ligand levels and osteoclast numbers, and reduction of bone loss.

51 Osteoblast and osteoclast number as well as mineral apposition rate wer

52 nsion on the graft outcome and assessment of osteoclast numbers as an indirect measure of a connectio

53 t numbers (68%) as well as a 40% decrease in osteoclast numbers as compared with the values from cont

54 cluded that SR can reduce RANKL activity and osteoclast numbers, as well as ABL.

55 ficient animals correlated with increases in osteoclast numbers, as well as with elevated expression

56 sis of hypertrophic chondrocytes and reduced osteoclast number at the border of marrow space.

57 ion, MMP-7 null mice had significantly fewer osteoclast numbers at the tumor-bone interface compared

58 In vitro, 2ME(2) repressed osteoclast number by inducing apoptosis of osteoclast pr

59 ing mAb inhibited IL-7-induced bone loss and osteoclast numbers by reducing Th17 cell numbers in the

60 c1, DC-STAMP, ATP6v0d1, and CD44, markers of osteoclast number, fusion, or activity, is lower in Cx37

61 lume, decreased cortical bone, and increased osteoclast number in bone explants in adiponectin knock-

62 ly active PPR induced a dramatic increase in osteoclast number in both trabecular and compact bone in

63 n vitro studies suggested that the increased osteoclast number in the mu-calpain(-/-) bones resulted

64 d bone resorption, as evidenced by decreased osteoclast number in vivo and impaired osteoclast format

65 teoporosis that is associated with increased osteoclast numbers in a rat model of the human disease o

66 amining the host response, colonization, and osteoclast numbers in aged versus young mice.

67 Osteoclast numbers in ligated group were significantly h

68 nd was associated with a failure to increase osteoclast numbers in the conditional knock-out mice.

69 g and wild-type mice were given ALN, and the osteoclast numbers in the inflamed joints and in the lon

70 ey increased with time with the exception of osteoclast numbers in the LIG model.

71 ALN reduced osteoclast numbers in the metaphyses by 97%, but by only

72 tibility, reflected by higher TNF levels and osteoclast numbers in the periodontium of aged versus yo

73 days of maximal mononuclear cell influx and osteoclast numbers in the rat and mouse.

74 Osteoclast numbers in the XG + ozone group were higher t

75 tally restricted decreases in osteoblast and osteoclast numbers in vivo.

76 ined bones from these animals and found that osteoclast number is increased two-fold.

77 e (500 micrograms), significant decreases in osteoclast number occurred in mutant mice compared to wi

78 eased bone marrow osteoclast progenitors and osteoclast numbers on bone surfaces.

79 nsity (NFBD); 3) total callus area (TCA); 4) osteoclast number (ON) in the callus region; and 5) newl

80 The correlations between osteoclast number or eroded surface and serum mineral pa

81 sorption in vitro without markedly affecting osteoclast number or the F-actin "ring" structure in pol

82 These changes were associated with low osteoclast number, osteoblast number, bone formation rat

83 noscale surface-adherent BMSCs increased the osteoclast number (P < 0.01).

84 group, and melatonin significantly decreased osteoclast numbers (P <0.05) but had no effect on iNOS,

85 creased trabecular separation, and increased osteoclast number per bone surface length.

86 hometric analysis of bone revealed decreased osteoclast number per millimeter of tumor/bone interface

87 g of trabecular branches, and a reduction in osteoclast number, suggestive of an early arrest of oste

88 last hyperactivation (including elevation of osteoclast number, surface area, and size) and increased

89 Osteoclast numbers, the size of the bone marrow spaces a

90 Osteoclast number was comparable in both genotypes, and

91 hed eroded perimeters despite an increase in osteoclast number were observed in histomorphometric mea

92 -resistant acid phosphatase-positive (TRAP+) osteoclast numbers were also evaluated.

93 he role of osteoclasts in tumor development, osteoclast numbers were elevated at the bone/tumor inter

94 Accordingly, osteoclast numbers were increased 122% compared with the

95 es were severely reduced, but osteoblast and osteoclast numbers were not significantly changed in the

96 TRAP staining showed that osteoclast numbers were reduced in both secondary ossifi

97 Periodontal tissue destruction and osteoclast numbers were significantly elevated in LIGPG

98 the LAPC-9 tibias under conditions in which osteoclast numbers were significantly reduced.

99 TRAP+ osteoclast numbers were the highest in the STZ+L group,

100 mice was associated with increased endosteal osteoclast numbers, with no significant effects on osteo

101 Analysis of osteoclast number within AIA joint revealed a reduction