1                           Dysplasias such as otosclerosis and osteogenesis imperfecta, the most frequ

2                                              Otosclerosis and Paget disease are CT diagnoses.

3 ly that was ascertained to have nonsyndromic otosclerosis but was subsequently found to have a congen

4 were found in seven patients in our familial otosclerosis cohort; three are missense mutations predic

5 c) flank the 14.5 cM region that contains an otosclerosis gene.

6 d a large multi-generational family in which otosclerosis has been inherited in an autosomal dominant

7                                              Otosclerosis is a relatively common heterogenous conditi

8                           Among white adults otosclerosis is the single most common cause of hearing

9 apes is usually progressive and secondary to otosclerosis, it may present congenitally, with other sk

10 non-neoplastic causes, such as otitis media, otosclerosis, or trauma.

11 d that SERPINF1-012 expression is reduced in otosclerosis patients with and without SERPINF1 mutation

12 ients with sporadic or familial nonsyndromic otosclerosis should be evaluated for mild features of th

13 6 affected persons have surgically confirmed otosclerosis; the remaining nine have a conductive heari

14 our families exhibiting dominantly inherited otosclerosis to identify 23 candidate variants (reduced