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1 ssociated with HLA class I-DSA could improve our understanding of ABMR and be useful for diagnostic o
2 rphism and argue that their approach can aid our understanding of adaptive conflicts between the sexe
3 ty protein states has broad implications for our understanding of allostery and suggests that the gen
4 These findings have the potential to improve our understanding of AMD pathogenesis, to support the de
9 l in several key areas, including furthering our understanding of bacteria, developing better suscept
10 ractions involving PAN have been implicated, our understanding of binding partners and PAN RNA bindin
15 research needs that, when met, will improve our understanding of carbon cycle dynamics, as well as f
16 are widely used for genome engineering, but our understanding of Cas9 specificity remains incomplete
18 al profiling with great potential to improve our understanding of cellular heterogeneity through disc
19 to fill gaps in trait coverage will improve our understanding of changes in fine-root traits across
20 both the laboratory and the field to deepen our understanding of chemical persistence in the environ
21 hoice signals in the VIP area, and challenge our understanding of choice signals in the brain.Choice-
24 xamine how this seminal study was pivotal to our understanding of CME and its progression into ever-i
26 umor subtypes in early stage tumors advances our understanding of common biology underlying breast ca
29 s in human pancreatic beta-cells, broadening our understanding of cytokine-induced beta-cell apoptosi
30 physicians and their patients and broadening our understanding of development of the ocular motor sys
31 ystem types and focused on water can enhance our understanding of differential ecosystem sensitivity
32 search is absolutely essential for improving our understanding of disease mechanisms contributing to
33 novel cellular model of LAM that can advance our understanding of disease pathogenesis and develop th
36 strating these various processes will deepen our understanding of domain-domain communication in nonr
37 (SVs) for a specific cancer type will deepen our understanding of driver mechanisms in cancer progres
40 ines function in model organisms may improve our understanding of dysfunctions of appetite and behavi
42 re remarkably common in early human embryos, our understanding of early embryonic somatic mutations i
43 ed altruism, with important implications for our understanding of economic and social interactions in
45 e expect this insight will decisively change our understanding of essential phenomena occurring withi
47 f T cells in Ebola survivors are scarce, and our understanding of EVD pathophysiology is limited.
49 tumor microenvironments, and further advance our understanding of factors that contribute to heteroge
52 ally influenced by genetic factors; however, our understanding of genetic pathways underlying individ
55 association studies (GWAS) have transformed our understanding of glioma susceptibility, but individu
56 ology, and biophysical studies have deepened our understanding of GPCR conformational regulation by d
57 f personal data clouds over time can improve our understanding of health and disease, including early
58 ncing (HTS) and bioinformatics have expanded our understanding of herpesviruses through genome-wide c
61 These findings may have implications for our understanding of how altered folate availability cau
63 gulation of Notch signaling, contributing to our understanding of how CSL functions as a transcriptio
64 erning cellular ATP production, and advances our understanding of how defective FA signaling contribu
65 ansley Insight focuses on recent advances in our understanding of how flowers manipulate physical for
66 behavior may have important implications for our understanding of how fluid flow influences biofilm b
67 ed by rewriting the genetic code will deepen our understanding of how genomes are designed and how th
69 olling cardiac specification is critical for our understanding of how heart formation is initiated du
70 his review will highlight recent advances in our understanding of how inflammation resolution may bec
73 dynactin-mitochondria interaction, enhancing our understanding of how mitochondria properly localize
74 his review highlights recent developments in our understanding of how neural circuits, pubertal hormo
75 or other histone chaperones, and it advances our understanding of how nucleosomes and their epigeneti
76 nalysis approaches, however, are simplifying our understanding of how p53 functions as a transcriptio
77 the atomic details of these structures helps our understanding of how proteins work together, how mut
78 interactions with heme and NCoR1 and advance our understanding of how signaling through HRMs affects
79 lutionary theoretical models that can deepen our understanding of how socioeconomic inequalities can
80 se events occur in the context of chromatin, our understanding of how TF-nucleosome interplay affects
81 ced reinstatement of alcohol seeking, expand our understanding of how the BLA-->NAc pathway regulates
83 ater isotope heterogeneity in plants and for our understanding of how the delta(18) O signal is incor
85 ct effects on sleep/wake behavior, improving our understanding of how the PPT nucleus regulates corti
87 g our interpretations of forest dynamics and our understanding of how these forests are responding to
88 der normal laboratory growth conditions, and our understanding of how they are silenced is in its inf
89 identity of these genetic factors, improving our understanding of how they shape retinal function.
90 in 3D chromosome structure and function, but our understanding of how various factors contribute to t
92 for comprehensive analyses that will promote our understanding of human biology and advance our effor
95 high altitude, and could have an impact upon our understanding of human diseases in which hypoxia is
97 systems-level analyses, this study advances our understanding of human neuroplasticity and its genet
100 , however, begin with an acknowledgment that our understanding of it as both a liquid and a solvent i
101 ion of centriole components have accelerated our understanding of its assembly, function, evolution,
102 e of inflammatory bowel disease has deepened our understanding of its pathogenesis through identifica
103 sis is critical to health, making furthering our understanding of L-R development an important concer
106 examines recent work that has contributed to our understanding of LOS-deficiency and compares it to s
108 tion and transdifferentiation data to foster our understanding of lymphoid/myeloid cell-fate decision
111 stigated, these new discoveries have changed our understanding of mechanisms underlying CNS immune pr
112 e of a central translocon component advances our understanding of membrane protein biogenesis and she
113 ntrolled in cultured cells in vitro However, our understanding of microtubule dynamics and functions
114 ve these findings will further contribute to our understanding of miRNA function in animals and benef
120 understanding of complex networks; however, our understanding of natural microecologies is limited.
122 cally their differential actions may advance our understanding of nervous system disorders and sugges
123 in a wider range of CPGs, perhaps clarifying our understanding of network principles underlying motor
126 nding fluctuating selection is important for our understanding of patterns of spatial and temporal di
127 recent paradigm shifts that have transformed our understanding of pediatric ocular motor disease at t
128 directly in a single nanostructure, limiting our understanding of phonon coupling with photons and pl
130 transport block steps in lysosomes, limiting our understanding of post-lysosomal transport steps.
132 review, we will summarize recent advances in our understanding of prostate and breast cancer disparit
136 ave broad implications for evolution and for our understanding of quantitative traits including compl
137 wever, scarce genomic resources have limited our understanding of regeneration in adult salamanders.
138 gen prediction and may have implications for our understanding of resistance mechanisms and immunothe
143 ntal property of Earth's oceans, critical to our understanding of seawater biogeochemistry, its long-
145 Nevertheless, significant gaps remain in our understanding of several crucial aspects of MP expos
147 ledge about RTK interactions and can further our understanding of signal transduction across the plas
148 This has significant global implications for our understanding of soil N cycling pathways and N2 O pr
152 n over the last decades has greatly advanced our understanding of stress responses in humans and thei
154 ludes annelid polychaetes but unfortunately, our understanding of such fauna is limited and their gen
155 ycling by microbes is critical for improving our understanding of supraglacial DOM cycling and the bi
156 n on how TCRs engage with MHC-Ia and MHC-II, our understanding of TCR/MHC-Ib interactions is very lim
158 une regulation and provide new insights into our understanding of the alterations of this biofluid du
159 in model mice in vivoSIGNIFICANCE STATEMENT Our understanding of the basis for intellectual impairme
161 Hypertension Trial)-Sodium Trial to further our understanding of the biological effects of sodium in
162 in vivo functions of ADAR enzymes, informing our understanding of the biological importance of A-to-I
163 olution of gene models will not only further our understanding of the biological processes of this pl
164 ith physiological measurements, has improved our understanding of the biological responses during dro
165 n this article, we review recent advances in our understanding of the biology of microglia, their con
166 -type deconvolution approaches are adding to our understanding of the biology underlying disease deve
167 ies in Parkinson disease patients, advancing our understanding of the brain regions involved in freez
169 subterranean methane sink and contribute to our understanding of the carbon cycle and ecosystem func
172 raints in sedimentary basins, which improves our understanding of the chronostratigraphy and evolutio
173 mparison of MRP1 and P-glycoprotein advances our understanding of the common and unique properties of
174 avasation and transmigration, which advances our understanding of the complex contribution of CtsB to
175 odiversity loss and food security, improving our understanding of the complex dynamics of the Earth s
176 Health Disparities Theme Issue that improve our understanding of the complex role of race in dispari
178 anti-inflammatory activities, indicates that our understanding of the composition of lipidome and the
179 ance spectroscopy (NMR) has greatly advanced our understanding of the composition of organic phosphor
180 nd the existence of NS5B crystal structures, our understanding of the conformational and dynamic beha
183 Work with this model system has enriched our understanding of the cyclopropanation-Cope rearrange
185 lex multisynaptic circuit would thus advance our understanding of the determinants of motivated behav
187 eractions between genes will further improve our understanding of the disease and help to uncover new
189 the first case was reported in 1981, most of our understanding of the disease treatments has been ext
191 his review is to describe recent advances in our understanding of the diverse mechanisms of action of
193 ow single-molecule approaches have increased our understanding of the dynamic behavior of complex mul
194 the past ten years or so, great advances in our understanding of the dynamics of elementary (bimolec
195 m social and ecological factors, and enhance our understanding of the dynamics of natural populations
197 Allee effects in social species will improve our understanding of the ecological and evolutionary imp
198 tion and residual confounding, thus limiting our understanding of the effect (if any) of inflammatory
199 vants to boost innate and adaptive immunity, our understanding of the effect of CpG-A and CpG-B on B
201 ated selection on behaviour are critical for our understanding of the evolution and maintenance of be
209 Next, we explore factors that have impeded our understanding of the GC and Tfh-cell processes invol
211 ic alterations remains a major bottleneck in our understanding of the genetic determinants of cancer.
212 2003, significant advances have been made in our understanding of the genetic makeup of diseases, esp
213 ration sequencing has substantially enhanced our understanding of the genetics of primary brain tumor
214 rs there have been extraordinary advances in our understanding of the genetics, genomics, biochemistr
215 tunistic mycoses have significantly expanded our understanding of the innate and adaptive immune mech
216 tified antiviral gene, as well as broadening our understanding of the innate immune response to dengu
219 ion across the Arctic Ocean helps to improve our understanding of the large-scale fate of DDTs in the
221 These findings represent a stride forward in our understanding of the malting process and provide a f
222 These studies significantly contribute to our understanding of the mechanism by which GRKs regulat
225 This sui generis cellulosome model enhances our understanding of the mechanisms governing the remark
227 ysine acetylome in SK-N-AS cells and expands our understanding of the mechanisms of perifosine action
229 tudies have not significantly contributed to our understanding of the molecular basis of trainability
230 udying bmr mutants has considerably expanded our understanding of the molecular basis underlying lign
232 al was not observed, leading to confusion in our understanding of the natural history of breast cance
233 However, until recently, deficiencies in our understanding of the nature of these cell population
234 acardiac organ dysfunction, numerous gaps in our understanding of the nature of this relationship exi
237 volution of spatial biases not only advances our understanding of the neural mechanisms underpinning
238 it," and has led to considerable advances in our understanding of the neurobiological basis of such b
241 handedness, implying a fundamental shift in our understanding of the ontogenesis of hemispheric asym
245 ent developments and discuss their impact on our understanding of the pathophysiology of PD, and the
246 in the lower urinary tract and contribute to our understanding of the pathophysiology of urinary rete
247 hione dynamics and transportation and expand our understanding of the physiological and pathological
248 e their medical relevance, there is a gap in our understanding of the physiological factors that medi
251 This article reviews recent advances in our understanding of the proteasome's multistep ATP-depe
252 accumulation, and discuss recent advances in our understanding of the regulatory control of carotenog
254 sis on diseased tissues has greatly advanced our understanding of the regulatory networks that drive
255 of postmortem human brain cells and further our understanding of the regulome and the impact of neur
256 eurobiological analysis allow a deepening of our understanding of the relationship between neuronal c
257 play important roles throughout biology, yet our understanding of the relationship between their sequ
258 hough significant advances have been made in our understanding of the relationship of the pathologica
259 hanges in photosynthetic infrastructure, but our understanding of the relative effects of these facto
260 cations for both species and may also add to our understanding of the role OC pesticides play in the
261 this novel strategy could greatly facilitate our understanding of the role of BMP in biological syste
264 e for theta oscillations in V1 and extending our understanding of the role of V1 in decision making.
265 tes and transgenic models, and could improve our understanding of the role the vasculature plays in b
266 nd and coastal wetlands globally can improve our understanding of the roles of wetlands in the global
267 Genomic and genetic approaches also improved our understanding of the signal repertoire used by AM fu
268 yostelium discoideum has greatly facilitated our understanding of the signal transduction and cytoske
270 s forest ecosystem and contributes to refine our understanding of the sources and processes that cont
271 tations of each of these methods used alone, our understanding of the systems-level mechanisms underl
273 veries and advances that have contributed to our understanding of the transcriptional networks underl
276 width, is an important yield component, but our understanding of the underlying genes and mechanisms
278 are important therapeutic targets; however, our understanding of their mechanism of action is limite
279 maintenance of proper synaptic connectivity, our understanding of their role in brain function is sti
281 nternational movements of malaria to improve our understanding of these phenomena and facilitate the
284 earch over the previous decades has improved our understanding of this complex arrhythmia while unrav
287 plete LRP1 ectodomain significantly advances our understanding of this important receptor and provide
288 o of them are stilbenoid-specific, advancing our understanding of this specialized enzyme family and
289 rEP uptake at the national level to increase our understanding of trends in its utilization, but nati
291 dient might be the next direction to improve our understanding of urbanization as an evolutionary pro
293 amination of these interactions could expand our understanding of viruses and be exploited for epidem
294 of sequence-based findings that can further our understanding of viruses in transplantation medicine
297 ectious agents transmit between hosts limits our understanding of what makes some pathogens so contag
298 h can be experimentally validated to improve our understanding of what triggers and maintains the gro
299 a wealth of primary data that could further our understanding of why ethnic minority populations are
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