ライフサイエンスコーパス: ovariectomy

1 roteasomal degradation following LTED (10-wk ovariectomy).

2 eveloped pulmonary hypertension (reversed by ovariectomy).

3 in female R192Q mutants and diminishes after ovariectomy.

4 reasing estrogen levels, nor increased after ovariectomy.

5 R signaling compromises the rise of LH after ovariectomy.

6 tests), again, when given testosterone after ovariectomy.

7 sex behaviors when given testosterone after ovariectomy.

8 s bone loss and restores the lost bone after ovariectomy.

9 ng a compensatory rise in LH secretion after ovariectomy.

10 (2)) or vehicle (VEH) for 3 months following ovariectomy.

11 e resorption, including that occurring after ovariectomy.

12 steoclast number and the bone loss caused by ovariectomy.

13 ne mass and blunted the bone loss induced by ovariectomy.

14 ABKO mice, heart size was normal, even after ovariectomy.

15 Mice underwent sham-ovariectomy or ovariectomy.

16 it-stem T-maze, was not affected by aging or ovariectomy.

17 as diminished after depletion of estrogen by ovariectomy.

18 ivity on the delayed response task following ovariectomy.

19 d this effect is significantly attenuated by ovariectomy.

20 formation have been prematurely arrested by ovariectomy.

21 ve cells after a 10 d, but not after a 30 d, ovariectomy.

22 stitial cells were also evident 6 days after ovariectomy.

23 h rates were not measurably affected by late ovariectomy.

24 e peaked at approximately 4 to 6 hours after ovariectomy.

25 bone mass and did not alter the response to ovariectomy.

26 innominata/nucleus basalis (SI/NB) following ovariectomy.

27 were observed in acinar regions 6 days after ovariectomy.

28 These effects were prevented by ovariectomy.

29 the MS, HDB and SI/NB, but not VDB following ovariectomy.

30 DNA laddering was more pronounced after ovariectomy.

31 FFS and OS were similar for goserelin and ovariectomy.

32 ule out a 50% improvement in survival due to ovariectomy.

33 e bone tissue after it has been perturbed by ovariectomy.

34 trous cycle, the proestrous phase, and after ovariectomy.

35 and is prevented by disuse but unaffected by ovariectomy.

36 ; or 4) caffeine/OVX = ingestion of caffeine/ovariectomy.

37 ive neural effects associated with bilateral ovariectomy.

38 ially protected from the bone loss caused by ovariectomy.

39 undetected in the apposition side even under ovariectomy.

40 nous sex hormone production was abrogated by ovariectomy.

41 in etidronate-treated rats, with or without ovariectomy.

42 s of dietary soy isoflavones before or after ovariectomy.

43 nd the role of female hormones was tested by ovariectomy.

44 This effect was blocked by ovariectomy (31 +/- 7) and totally reversed by estrogen

45 lateral," "mastectomy," "oophorectomy," and "ovariectomy," a MEDLINE search of the English-language l

46 We found that while ovariectomy abolished pLTF, it could be restored by acut

47 ly improved the metabolic functions, whereas ovariectomy abolished this protective effect.

48 Importantly, orchiectomy, but not ovariectomy, abolishes the sex differences in ILC2 devel

49 ) during their reproductive period; however, ovariectomy accelerates GS progression.

50 hat were degranulated compared to that after ovariectomy alone, an effect that was most apparent in t

51 eu, the present study examined whether adult ovariectomy altered the magnitude of systemic morphine a

52 e periods of estrogen deprivation induced by ovariectomy and 17beta-estradiol (E(2)) replacement.

53 ded 334 unique genes that were altered after ovariectomy and additionally changed by one or more anti

54 ts biological activity from the circulation: ovariectomy and administration of neutralizing antibodie

55 applied two models of ovarian steroid loss, ovariectomy and chemically-induced ovarian failure, to e

56 Hormone therapy was initiated at the time of ovariectomy and cognitive function was reassessed at 2,

57 HBV titers increased in female mice after ovariectomy and decreased in male mice supplemented with

58 used a mouse model of surgical menopause by ovariectomy and demonstrate a protective role for estrog

59 only prevented the bone loss associated with ovariectomy and did not increase bone mass.

60 of its ER coactivation, as both approaches, ovariectomy and ER-/- crosses, still resulted in a high

61 , whereas lung ILC2s were unaffected by both ovariectomy and estrogen administration.

62 We studied the effect of ovariectomy and estrogen replacement on tumor formation

63 Ovariectomy and estrogen supplementation were used to ev

64 is directly, we subjected Cav-1(-/-) mice to ovariectomy and estrogen supplementation.

65 Previous studies have shown that ovariectomy and hypophysectomy cause regression of the l

66 emale rats in the proestrous phase and after ovariectomy and in male rats.

67 supplementation, and that the combination of ovariectomy and letrozole further reduced the frequency

68 beta-oestradiol was initiated at the time of ovariectomy and maintained throughout the 10-week oestro

69 Therefore, a new rat model of combined ovariectomy and multiple-deficient diet was established

70 Two weeks afterward, ovariectomy and proestrus sham-ovariectomy mice were sub

71 h in vagina-projecting sensory neurons after ovariectomy and reduced by estrogen.

72 Female gender, which is abolished following ovariectomy and reproductive senescence, is associated w

73 Protection in females was disrupted by ovariectomy and restored by short-term estrogen administ

74 d two- to threefold between 2 and 8 wk after ovariectomy and returned to control levels by 16 wk.

75 an effect that was blunted significantly by ovariectomy and reversed by estrogen replacement.

76 ccumulation, an effect that was minimized by ovariectomy and reversed partially by estrogen replaceme

77 This sex difference was abrogated by ovariectomy and senescence and was partially restored by

78 sing in Wnt-1 TG mice are refractory to both ovariectomy and the ER antagonist tamoxifen, but lose ER

79 ling and postpartum (Experiment 1), or after ovariectomy and treated with empty and hormone-filled ca

80 er in Tgfbeta 1+/- than wild-type mice after ovariectomy and treatment with estrogen and progesterone

81 ls in the attention task was increased after ovariectomy and was reduced in monkeys treated with ERT.

82 ll substantially in rodent bone marrow after ovariectomy and were rapidly normalized by exogenous 17-

83 e animals, exacerbation of the disease after ovariectomy, and a strong protective effect of estrogen:

84 This difference was abolished after ovariectomy, and administration of 17-beta-estradiol ben

85 sured before ovariectomy, for 2 months after ovariectomy, and at 14 months after treatment with place

86 mineralization, reversed bone loss caused by ovariectomy, and increased bone strength.

87 Three weeks post-ovariectomy, animals received estradiol benzoate (EB, 0.

88 tial learning in the Morris water maze after ovariectomy, appropriate control treatment, or one of tw

89 ociated with more severe bone loss following ovariectomy as compared with that in syngeneic WT mice.

90 CLA supplementation significantly prevented ovariectomy-associated weight and fat mass gain, compare

91 ) treatment given immediately at the time of ovariectomy attenuated central and peripheral production

92 In mice, ovariectomy before preimplantation ovarian estrogen secr

93 ment with an estrogen receptor antagonist or ovariectomy but restored after administration of estradi

94 ryos survive unimplanted in the uterus after ovariectomy but, in contrast to wild-type or heterozygou

95 e responsible for this sexual dimorphism, as ovariectomy, but not castration, of Nf1-OPG mice normali

96 ve action when administered immediately upon ovariectomy, but not when administered after 10 weeks of

97 in amyloid-beta (Abeta) deposition following ovariectomy/castration.

98 highly mineralized and more cellular, while ovariectomy caused a reduction in both mineralization de

99 on of lacrimal gland sections indicated that ovariectomy caused apoptosis of interstitial cells rathe

100 Finally, ovariectomy caused bone loss in wt mice and in mice lack

101 Here we show that ovariectomy causes an accumulation in the BM of reactive

102 Elimination of endogenous oestrogen by ovariectomy causes weight gain that can be reversed or p

103 Post-ovariectomy consumption of soy was associated with highe

104 e of endogenous ovarian Ag, because neonatal ovariectomy converted the female response to that of mal

105 After ovariectomy, cortical and trabecular bone loss was reduc

106 ovariectomized (OVX) and, 10 days following ovariectomy (day 0), injected with corn oil (vehicle), e

107 The goserelin/ovariectomy death hazards ratio was .80 and the associat

108 mental metastases model, we demonstrate that ovariectomy decreased the frequency of magnetic resonanc

109 Finally, ovariectomy depressed RhoA activity, spine cytoskeletal

110 ice had equivalent levels of bone loss after ovariectomy despite mkp-1(-/-) mice having fewer osteocl

111 e having higher levels than female mice, and ovariectomy did not alter this phenotype.

112 Ovariectomy did not change the time to onset of vitamin

113 Females depleted of endogenous hormones by ovariectomy did not exhibit a change in prevalence of ad

114 Ovariectomy did not impair water maze performance; howev

115 Ovariectomy did not significantly reduce disease in B10.

116 rs to be affected by ovarian hormone levels; ovariectomy diminished the number of BrdU-labeled cells,

117 In contrast, ovariectomy does not affect kidney injury induced by isc

118 We found that ovariectomy-enhanced T-cell production of TNF-alpha, whi

119 We show that ovariectomy enhances the production of the osteoclastoge

120 A combination of ovariectomy, estrogen receptor antagonism, and estrogen

121 In contrast, ovariectomy exacerbated age-related deficits in object d

122 Moreover, ovariectomy exacerbated infarction in wild-type females,

123 To determine whether ovariectomy exacerbates age-related cognitive decline, t

124 doses that ameliorate the adverse effect of ovariectomy, exogenous beta-estradiol appears to have no

125 Ovariectomy failed to induce bone loss, stimulate bone r

126 eaction time motor tasks was measured before ovariectomy, for 2 months after ovariectomy, and at 14 m

127 premenopausally then casein/lactalbumin post-ovariectomy had higher relative hippocampal content of g

128 Because ovariectomy had no effect on the CHS response following

129 After ovariectomy, histamine-deficient mice were protected fro

130 ses and 4,611 controls) who provided data on ovariectomy, hysterectomy, and tubal sterilization durin

131 animals at hormone administration and test, ovariectomy implementation, when to administer hormones

132 preventing osteoporotic bone loss induced by ovariectomy in adult mice.

133 The removal of ovarian steroid by ovariectomy in adults did not alter the onset rate.

134 However, ovariectomy in adults increases Acrp30.

135 over 50% with surgical menopause induced by ovariectomy in aged monkeys.

136 cal menopause, long-term (10-week) bilateral ovariectomy in female rats.

137 Ovariectomy in female wild-type mice caused a 50% increa

138 line values following 2, 12, or 24 months of ovariectomy in monkeys.

139 en 56 and 59 nm is present 2 years following ovariectomy in ovine dermal samples.

140 ts the osteoclast differentiation induced by ovariectomy in the apposition side of the periodontium b

141 A deficit first occurred 4 months after ovariectomy in working memory, which was tested in a del

142 In addition, ovariectomy increased La expression in ductal cells.

143 In this study, we found that ovariectomy increased the number of bone marrow T cell-p

144 Ovariectomy increases food intake, which can be normaliz

145 els in K14-PTHrP fibroblasts in vitro, while ovariectomy increases Tgfb1 levels in K14-PTHrP ventral

146 n be effectively blocked by antiestrogen and ovariectomy, indicating that the induced proliferation i

147 Ovariectomy induced 3.61-fold and 6.34-fold increases in

148 Furthermore, ovariectomy induced bone loss, which was absent in T cel

149 esting to the essential contribution of TNF, ovariectomy induced rapid bone loss in wild type (wt) mi

150 s increases bone mass and protects mice from ovariectomy-induced (OVX-induced) osteoporosis.

151 e of the apoptosis, and to determine whether ovariectomy-induced apoptosis could be prevented by dihy

152 s well as in mouse models, for the rescue of ovariectomy-induced bone loss and ear inflammation.

153 as a role in the regulation of bone mass and ovariectomy-induced bone loss and that CB1- and CB2-sele

154 a(-/-) mice were partially protected against ovariectomy-induced bone loss by estradiol, confirming t

155 bitors parthenolide and BMS-345541 prevented ovariectomy-induced bone loss by inhibiting osteoclastic

156 n vivo showed that HCT1026 protected against ovariectomy-induced bone loss by inhibiting osteoclastic

157 yy(-/-) mice showed a greater sensitivity to ovariectomy-induced bone loss compared with wild-type li

158 In contrast, estradiol prevented ovariectomy-induced bone loss in ERbeta(-/-) mice, as in

159 e such compound, 55 (ABD295), fully reversed ovariectomy-induced bone loss in mice at a dose of 5 (mg

160 in either B or T lymphocytes contributes to ovariectomy-induced bone loss in mice.

161 was highly efficacious in the prevention of ovariectomy-induced bone loss in the rat when administer

162 tagonists of CB1 and CB2 receptors prevented ovariectomy-induced bone loss in vivo and caused osteocl

163 one resorption in vitro and protects against ovariectomy-induced bone loss in vivo by a novel mechani

164 thenolide on bone cell function in vitro and ovariectomy-induced bone loss in vivo.

165 ic bone resorption in vitro and that prevent ovariectomy-induced bone loss in vivo.

166 tic bone formation in vitro and that prevent ovariectomy-induced bone loss in vivo.

167 n vivo administration of GW9508 counteracted ovariectomy-induced bone loss in wild-type but not GPR40

168 s of these agents on osteoblast function and ovariectomy-induced bone loss remain unknown.

169 ion mice were osteopetrotic and resistant to ovariectomy-induced bone loss, while gain-of-function an

170 ncrease tissue glutathione levels, abolished ovariectomy-induced bone loss, while l-buthionine-(S,R)-

171 on of Tph1, increases bone mass and prevents ovariectomy-induced bone loss.

172 e increased bone mass and are protected from ovariectomy-induced bone loss.

173 and that its neutralization in vivo prevents ovariectomy-induced bone loss.

174 in vivo was assessed using a mouse model of ovariectomy-induced bone loss.

175 dies showed that a soy-protein diet prevents ovariectomy-induced bone loss.

176 Snca regulates bone network homeostasis and ovariectomy-induced bone loss.

177 of RANKL from T lymphocytes had no impact on ovariectomy-induced bone loss.

178 osteoblast function which could not overcome ovariectomy-induced bone resorption.

179 systemic treatment with Debio0719 prevented ovariectomy-induced cancellous bone loss.

180 A challenge with scopolamine revealed that ovariectomy-induced cognitive deterioration coincided wi

181 Ovariectomy-induced depletion of sex steroid hormones in

182 GNDs) in animal models of high-fat diet- and ovariectomy-induced obesity.

183 ption, it inhibited parathyroid hormone- and ovariectomy-induced OC activation in WT, but not cKO, mi

184 astogenesis are substantially protected from ovariectomy-induced osteoporosis and the periarticular o

185 ment with the S1P(1) agonist FTY720 relieved ovariectomy-induced osteoporosis in mice by reducing the

186 Consequently, ovariectomy-induced osteoporosis, as well as bone metast

187 In an in vivo model of murine ovariectomy-induced osteoporosis, pharmacological inhibi

188 cilitates femur fracture repair in rats with ovariectomy-induced osteoporosis.

189 ransfer arthritis, tumor growth in bone, and ovariectomy-induced osteoporosis: all conditions associa

190 Importantly, this and other ovariectomy-induced outcomes of UTI were reversible upon

191 regulation was assessed in two rat models of ovariectomy-induced thermoregulatory dysfunction.

192 mperature regulation in two rodent models of ovariectomy-induced thermoregulatory dysfunction.

193 with the antidiabetic drug metformin during ovariectomy-induced weight gain caused tumor regression

194 Estradiol replacement after ovariectomy inhibited gonadotropin release to a similar

195 Our results show that ovariectomy intensifies colchicine-induced granule cell

196 After ovariectomy, intestinal adenomas in Min/+ mice increased

197 llectively, the data indicate that long-term ovariectomy is associated with a decline in response to

198 e hypothesis that glandular regression after ovariectomy is due to apoptosis, to identify the cell ty

199 Glandular atrophy observed after ovariectomy is likely to proceed by necrosis of acinar c

200 The mutant mice lost more bone after ovariectomy likely resulting from decreased osteoblast f

201 f IFN-gamma in 3 mouse models of bone loss - ovariectomy, LPS injection, and inflammation via silenci

202 However, the findings suggest that long-term ovariectomy may protect against the development with agi

203 ks afterward, ovariectomy and proestrus sham-ovariectomy mice were subjected to laparotomy (i.e., sof

204 Adult ovariectomy minimally affected morphine analgesia in neo

205 to achieve very low estrogen levels, and the ovariectomy model lacks a perimenopause phase.

206 osteolysis, inflammatory arthritis and post-ovariectomy models.

207 GSK126 attenuated bone loss in the ovariectomy mouse model of postmenopausal osteoporosis.

208 After ovariectomy, neointimal growth in wild-type mice was alm

209 culating female sex hormones were reduced by ovariectomy of 8-week-old female CBA/J mice.

210 Ovariectomy of female rats increased BK-induced PE, and

211 Ovariectomy of infant mice does not interfere with the p

212 Prepubertal ovariectomy of Wnt-1 TG mice also extended tumor latency

213 gh two independent approaches, by performing ovariectomy on AIB1 transgenic (AIB1-tg) mice to prevent

214 at hypofunction has a greater influence than ovariectomy on mandibular bone.

215 did not influence the stimulating effect of ovariectomy on osteoblastogenesis or osteoclastogenesis.

216 Further, the effects of ovariectomy on these afferent systems were differentiall

217 On day 21 after ovariectomy, one first mandibular molar received a ligat

218 astogenesis and bone loss induced in mice by ovariectomy or low dietary calcium, in the latter case i

219 Mice underwent sham-ovariectomy or ovariectomy.

220 This natural protection is lost after ovariectomy or reproductive senescence.

221 ned with colchicine or vehicle 2 weeks after ovariectomy or sham operation.

222 istar rats were randomly subjected to either ovariectomy or sham operation.

223 Furthermore, ovariectomy or treating female mice with an estrogen rec

224 mice, and these differences are abrogated by ovariectomy or treatment with flutamide.

225 Simple reaction time was not altered after ovariectomy or treatment.

226 ale sheep were randomized to sham operation, ovariectomy, or ovariectomy plus 17beta-estradiol replac

227 iectomized (OVX) = non-ingestion of caffeine/ovariectomy; or 4) caffeine/OVX = ingestion of caffeine/

228 and sheep divided into four groups: control, ovariectomy, ovariectomy with dietary limitation, and ov

229 Following ovariectomy (OVX) (n = 6) or sham-operation (n = 6) intr

230 t was created using unilateral and bilateral ovariectomy (OVX) along with intact (SHAM) control.

231 amined the effects of estrogen deficiency by ovariectomy (OVX) and 17beta-estradiol (E(2)) replacemen

232 g mechanism, we manipulated estrogen through ovariectomy (OVX) and estradiol administration.

233 Thus, we determined the effect of ovariectomy (OVX) and estrogen replacement on the ultras

234 NOS(-/-)) were studied intact (INT) or after ovariectomy (OVX) and implantation of E(2) or vehicle (V

235 xpressing galanin in mice was high following ovariectomy (OVX) and the treatment of OVX mice with est

236 We now show that ovariectomy (ovx) disregulates T lymphopoiesis and induc

237 mpensated loss of ovarian hormones following ovariectomy (OVX) elevates the risks of cognitive impair

238 Here we show that ovariectomy (ovx) expands short-term HSPCs (ST-HSPCs) an

239 The bone loss induced by ovariectomy (ovx) has been linked to increased productio

240 A previous study showed that ovariectomy (ovx) in aged rats enhanced spatial working

241 igh-fat diet (HFD) when given at the time of ovariectomy (OVX) in mice.

242 ther prolonged hormone deprivation caused by ovariectomy (OVX) in young adult rats prevents the abili

243 and long-term ovarian hormone loss following ovariectomy (OVX) is associated with cognitive impairmen

244 Although research suggests that ovariectomy (ovx) is detrimental to spatial cognition in

245 Effects of ovariectomy (OVX) on performance of the memory tasks, Ob

246 Rats then underwent either ovariectomy (OVX) or sham surgery and thereafter either

247 Ovariectomy (ovx) reduced the total body BMD and the tra

248 imentally induced periodontitis in rats with ovariectomy (OVX) that are or are not treated with estro

249 effect of caffeine is influenced by gender, ovariectomy (OVX), and then exogenous estrogen in the mo

250 is instrumental for the bone loss induced by ovariectomy (ovx), but the responsible mechanism is unkn

251 Ten days following ovariectomy (OVX), groups of female rats were injected e

252 tation of SHED via the tail vein ameliorates ovariectomy (OVX)-induced osteopenia by reducing T-helpe

253 Additionally, the GNPs-ALD were applied to ovariectomy (OVX)-induced osteoporotic mice and the expe

254 In the ovariectomy (OVX)-induced osteoporotic mouse model, seru

255 ERalpha-/AA mice exhibited elevated LH after ovariectomy (OVX).

256 tion, and the resulting bone loss induced by ovariectomy (ovx).

257 stradiol (E2) signaling in rats 1 week after ovariectomy (OVX).

258 es, soon after surgically-induced menopause [ovariectomy (OVX)], on tests of memory and attention.

259 diet (HFD) after weaning, followed later by ovariectomy (OVX; as a model of menopause).

260 after the loss of ovarian function (surgical ovariectomy; OVX).

261 ty to characterize a window of commitment by ovariectomy/palpation studies permitted microarray analy

262 andomized to sham operation, ovariectomy, or ovariectomy plus 17beta-estradiol replacement.

263 ndronate on bone formation activity and that ovariectomy plus raloxifene resembles sham more closely

264 rce of isoflavones, fed immediately after an ovariectomy prevents bone loss in rats.

265 However, there is evidence indicating that ovariectomy prevents the development of both ER-positive

266 xplicably, there is evidence indicating that ovariectomy prevents the formation of both estrogen rece

267 However, whereas ovariectomy produced a modest net decrease in the densit

268 Ablation of estrogen signaling through ovariectomy produced nipples with abnormally thin epider

269 odel by steroid administration combined with ovariectomy recapitulates decreased bone formation and s

270 Recent studies have shown that ovariectomy reduces, and subsequent hormone replacement

271 Ovariectomy resulted in 644 significant probe set change

272 Ovariectomy resulted in bone- and bone compartment-speci

273 Goserelin and ovariectomy resulted in similar FFS and OS.

274 ifferences in predicted DNA methylation age, ovariectomy results in significant age acceleration in f

275 Tissue taken 4 hours and 6 days after ovariectomy showed nuclear chromatin condensation princi

276 wing vehicle and morphine treatment, whereas ovariectomy significantly attenuated the enhancement of

277 Ovariectomy significantly decreased the magnitude of the

278 Prophylactic ovariectomy significantly delayed tumor development and

279 Further, ovariectomy studies show that the health benefits gained

280 ncrease in BK-induced PE as adrenalectomy or ovariectomy, suggesting that the adrenal medullary facto

281 tively, these analyses support the use of an ovariectomy surgery rat model to gain insights into the

282 ho enter menopause prematurely via bilateral ovariectomy (surgical menopause) have a significantly in

283 the pituitary and hypothalamus in rats after ovariectomy than in rats in the proestrous phase.

284 tion in the BM is an upstream consequence of ovariectomy that leads to bone loss by activating T cell

285 rease in bone marrow B lymphocytes caused by ovariectomy that occurred in control littermates.

286 On the 8th day after ovariectomy, they were injected with estrogen (30 microg

287 one loss and chronic inflammation induced by ovariectomy, tumor necrosis factor or natural aging.

288 Here we show that ovariectomy up-regulates IFN-gamma-induced class II tran

289 Bilateral ovariectomy was associated with reduced breast cancer ri

290 percentage of degraded DNA at 24 hours after ovariectomy was not different from controls examined at

291 The percentage of degraded DNA 6 days after ovariectomy was significantly increased (8.5%+/-2.4%), c

292 dition, KO mice maintain bone mass following ovariectomy, whereas wild-type mice lose approximately o

293 In contrast, prepubertal ovariectomy, which arrested mammary epithelial developme

294 otected female mice from bone loss following ovariectomy, which induces osteoporosis in WT females.

295 my, ovariectomy with dietary limitation, and ovariectomy with dietary limitation and steroid injectio

296 ided into four groups: control, ovariectomy, ovariectomy with dietary limitation, and ovariectomy wit

297 Using ovariectomy with or without estrogen replacement, we als

298 morphogenesis in tissue repair, we performed ovariectomy with resection of the corresponding branches

299 female mice underwent estrogen depletion by ovariectomy, with or without supplementation with exogen

300 ved with tubal sterilization only or partial ovariectomy without hysterectomy.