ライフサイエンスコーパス: over

1 ingle- and multi-site cohorts, and increased over 1 year in Parkinson's disease but not in controls a

2 ally with repeated bronchial challenge tests over 1 year.

3 absorptive roots to maintain respiration for over 1 yr.

4 therapy (4 mg/kg padeliporfin intravenously over 10 min and optical fibres inserted into the prostat

5 o slow but progressive nodal destabilization over 10 months, primarily affecting betaIV spectrin, fol

6 In just the past 5 years, over 100 antisense oligonucleotide-based therapies have

7 Using unbiased proteomic profiling of over 100 different cytokines, we found that Lipocalin-2

8 tides found in DNA of eukaryotic cells, with over 100 million rNMPs transiently incorporated in the m

9 h of over 1000 MPa, and bearable pressure of over 100 MPa.

10 or 3.6 mWh cm(-3), high tensile strength of over 1000 MPa, and bearable pressure of over 100 MPa.

11 dose of 36.63 Gy in 11 fractions of 3.33 Gy over 11 days to the chest wall and the draining regional

12 Finally, participants transplanted over 11 y ago showed the highest levels of Streptococcus

13 Fullerene-free organic solar cells show over 11% power conversion efficiency, processed by low t

14 rences in MD by age and menopausal status in over 11,000 breast-cancer-free women aged 35-85 years, f

15 inics in 101 health centers throughout Spain over 12 months.

16 Gene structure was improved in over 13% of genes, and 651 novel genes were predicted by

17 n genes have been commercially available for over 15 years and are providing significant value to gro

18 a two- to fourfold increased risk of relapse over 16-32 weeks.

19 n humans moved from Asia toward the Americas over 18,000 y ago and eventually peopled the New World t

20 At regular intervals over 180 min, appetite (visual analog scales), gastric e

21 keletal muscle (SM) mass and selected organs over 2 y using MRI in overweight adults with type 2 diab

22 predicted to be more effective if continued over 2 years rather than 1 year, and if done at the time

23 cialty care program, to usual community care over 2 years.

24 red the distance of wheat allergen dispersal over 20 minutes using a petri dish and immunochromatogra

25 A total of 55,532 transcripts with lengths over 200 bp were de novo assembled.

26 f PTDM and a manageable tolerability profile over 24 weeks of treatment.

27 were repeat clinic presentations and growth over 24 wk.

28 BMI over 25 kg/m(2), diabetes, past and current smoking, red

29 essions) or treatment as usual (TAU) control over 25 wk.

30 y) at sublethal, field-realistic doses given over 3 days.

31 unsellors, enhanced remission and abstinence over 3 months among male primary care attendees with har

32 prospective multicenter observational study over 3 months of all patients receiving mechanical venti

33 r adults aged 60 years or older (n = 16,770) over 3 time periods in the National Health and Nutrition

34 ivers (Kolyma, Lena, Yenisei, Ob, Mackenzie) over 3 years with seasonal sampling periods using measur

35 Muscle alpha-tocopherol concentration was over 3.5-fold higher in supplemented samples than in con

36 eived melphalan at 200 mg/m(2) intravenously over 30 min on 1 day, followed by ASCT (control group).

37 stain 80% of their "post burn-in" efficiency over 3400 h under full sun illumination in ambient condi

38 ns of approximately 1.1M individuals who ran over 350M km in a global social network over 5 years.

39 hypofractionated RT of 60 Gy in 20 fractions over 4 weeks.

40 Kaplan-Meier incidence over 4 years was 0.042 (95% CI, 0.032 to 0.056) in the v

41 nd graft survival, and stable renal function over 4 years.

42 iB) positron emission tomography, gait speed over 4.57 m (15 ft), and cognition on the Mini-Mental St

43 s in life-years per 100 000 total population over 40 years (to 2050).

44 chanism for alkane hydroxylation was invoked over 40 years ago to help explain reactivity patterns in

45 Despite cessation of stocking over 40 years ago, hybridization increased over time at

46 This approach permitted rapid evaluation of over 400 admixture combinations for the oxidative methyl

47 ring our results with observed properties of over 400 CMEs, we show that CMEs cease to be coherent ma

48 l 400 mg/m(2) bolus followed by 2400 mg/m(2) over 46 h).

49 ffect was observed in [(18) F]Nifene binding over 5 decades.

50 d the response of mobile estuarine consumers over 5 months to changes in habitat availability in situ

51 ran over 350M km in a global social network over 5 years.

52 ndent of surgical indication, compared to PK over 5 years.

53 igh incident photon-to-current efficiency of over 50 % at 400 nm were achieved with incorporation of

54 Initial screening of a series of over 50 newly characterized 2-aminopyrimidines with affi

55 ism reduces the maximum thrombin response by over 50%.

56 Here we use precise data on over 50,000 Drosophilid fly wings to demonstrate unexpec

57 nge in Argentina [6], subsequently expanding over 500 km from its starting point [7-11].

58 We find that over 5000 distal noncoding regions exhibit dynamic chang

59 keletons have evolved 18 times independently over 550 MYA and are essential for the success of the Ga

60 arvae (lower dose of 0.033 microg/larvae/day over 6 days) and, in a separate experiment, adults (lowe

61 A photocurrent of over 6.8 mA cm(-2) and an accordingly high incident phot

62 for visualizing soft tissue and organs, with over 60 million MRI procedures performed each year world

63 gether, showing a significant improvement of over 600%.

64 es monitored in St. Croix, US Virgin Islands over 7 years (2004-2011), and validated with data from 2

65 to conventional RT of 78 Gy in 39 fractions over 8 weeks or to hypofractionated RT of 60 Gy in 20 fr

66 We observed that individuals over 90 years old carried low levels of heteroplasmic v

67 erage, CP-PCB_126 individually accounted for over 95% of the total CP-PCB TEQ.

68 ting both DNA strands simultaneously with an over 98.6% coverage.

69 Change in BCVA in STGD1 patients over a 12-month period was small, but varied depending o

70 c channel that produced a linear SS gradient over a 20mm field ranging from 0-16 dynes/cm(2).

71 n 3D images showing MOF uptake by HeLa cells over a 24 h period.

72 acteristics of pediatric nystagmus diagnosed over a 30-year period.

73 Over a 40 year time horizon, incremental cost-effectiven

74 viewed 69 paediatric MRI sedations performed over a 5-year period using records of patients' biodata,

75 ol several optical properties simultaneously over a broad frequency range.

76 ntist may publish tens or hundreds of papers over a career, but these contributions are not evenly sp

77 and have been used as physical evidence for over a century.

78 ptional repression has been well studied for over a decade, the DNA-binding activities and the biolog

79 We mimicked natural fluctuations in light over a diurnal period to examine the effect on the photo

80 This provides temporally precise information over a heterogeneous population in promising tasks for t

81 tina, we conclude that vigilance is required over a large area to prevent the establishment of this t

82 es eukaryotic cells to directionally migrate over a large dynamic range of chemoattractant.

83 haviours: +138%; inability to ascend: +280%) over a longer period (60 min).

84 for these patients was -0.12+/-0.51 dB/year over a mean follow-up period of 10.4+/-3.7 years.

85 arction, or unstable angina hospitalizations over a median follow-up of 26.1 months.

86 n, and mean eGFR was 94 ml/min per 1.73 m(2) Over a median follow-up of 8 years, 228 (6.4%) cases of

87 s of a chemical warfare nerve agent simulant over a polyoxometalate catalyst.

88 ight by 12 months, a significant improvement over a prescreening cohort of newborns with CF from 20 y

89 As viruses were found in over a quarter of isolates tested, many more are likely

90 red seeds were determined by incubating them over a range of alternating temperature regimes in light

91 The use of microviscosity is valid over a range of different solvent system types, includin

92 at oxidation during exercise in race walkers over a range of exercise intensities.

93 (P=0.009), and 18% (P=0.004), respectively, over a total of 20 years of follow-up.

94 on with a standardized AP parameter analysis over a wide range of AP waveforms and firing rates, owin

95 nt crystalline forms of cellulose and chitin over a wide range of temperatures, pH levels, and ionic

96 While ATP depletion led to cell death, over-acetylated tubulin led to inhibition of motility an

97 Genetic and cell biological studies over almost 2 decades have revealed some 30 proteins inv

98 proprietary data, (2) choosing Random Forest over alternative tested Machine Learning methods, and (3

99 Over an 8-year study period, a total of 1283 pregnancies

100 Results Over an average of 7.2 years of follow-up (2004 to 2011)

101 Most of these extinctions will occur over an extended time, and therefore, reconnecting fragm

102 t to 6.5 x 10(-11) mol m(-2) s(-1), which is over an order of magnitude greater than the rate of pyri

103 was associated with reduced GMVs and NAA/Cr, over and above the effects of fatigue, depressive sympto

104 quency-dependent, cell-type-specific control over BA circuitry via 5-HT and glutamate co-release to i

105 s useful in helping to identify target odors over background.

106 ass correlation coefficient =0.931; P<0.001) over both iterative and aortic velocity-time integral me

107 d increase in widespread extreme rain events over central India during 1950-2015.

108 d provide incremental prognostic information over clinical and conventional echocardiographic charact

109 F-alpha/FNAB/PMMA matrix was then integrated over comb structured gold electrode array based sensor c

110 moselectivity for the amination of C-H bonds over competing reduction of the azide substrate to a sul

111 of electrochemical carbon dioxide reduction over CuAg bimetallic electrodes and surface alloys, whic

112 This is an advance over current discrimination tests, which ask subjects to

113 utions, demonstrating significant advantages over current methods.

114 ctive vaccine would have distinct advantages over current therapeutic options, yet experimental vacci

115 anisms to oxygen up-regulation likely varies over depth.

116 d number word knowledge influence each other over development and contribute to the development of th

117 This allows us to compare conservation over different evolutionary timescales.

118 S) of sedimentary sulfate and sulfide phases over Earth history can be used to infer substantive chan

119 es in a variety of species might play a role over evolutionary timescales.

120 left hemisphere in neglect is pathologically over-excited it ought to be suppressed.

121 oenzyme-A reductase (HMGCR), was found to be over-expressed in all ovarian cancer cell lines examined

122 y, we show, in a quad-transgenic model, that over-expression of VEGF-A165 b alone is sufficient to re

123 re observed in miR156-impervious 35S::SPL13m over-expression plants.

124 silencing of PrP(C) decreases ferritin while over-expression upregulates ferritin and divalent-metal-

125 l mode of action of Wnt5a and its regulation over genes associated with progenitor proliferation.

126 sion length beyond which selection dominates over genetic drift; (2) a characteristic angular correla

127 Over half of caregivers whose children got 3 or more inj

128 e a preference for using lower gauge needles over higher gauge needles with more passes.

129 iation was assessed by repeated measurements over hours and days both in phantoms and in vivo.

130 tion sample of 2415 people aged 40 years and over in Australia.

131 emonstrate the advantage of skin vaccination over intramuscular delivery of a two-fold higher vaccine

132 ominance of the melanophilin adaptor protein over its associated motor and offer an unexpected mechan

133 s proven to be robust with high-yield (>98%) over large areas (1 cm(2)) and of general validity for b

134 n degradable materials at ambient conditions over large areas, with key advantages over strategies ba

135 live animals, achieving micromolar precision over many hours without the use of physical barriers or

136 , suggesting a new avenue for active control over molecular function.

137 hat divalent cations are preferentially lost over monovalent cations upon A.C protonation, providing

138 show for a wildfire chronosequence spanning over more than 5000 years in boreal forest in northern S

139 mans benefited from some selective advantage over Neanderthals, which led to the their extinction.

140 rexpression resulted in a net increase in HR over NHEJ.

141 mental insight, C-H bond cleavage in methane over Ni-based catalysts was investigated.

142 rall, our results indicate that stress cross-over occurs in animal populations and may have important

143 Such form of cross-over of stress may be beneficial if it enhances adaptive

144 In this study, we used insurance claims for over one-third of the entire US population to create a s

145 Agreement over optimal AVD was superior when assessed by flow reve

146 ne whether people from sexual minorities are over- or under-represented among different cancer sites.

147 terhemispheric hydrologic seesaw is apparent over orbital and glacial-interglacial timescales, but it

148 uperiority of hyperfractionated radiotherapy over other altered fractionation radiotherapy regimens a

149 increase in power to detect genetic effects over other approaches and identifies new associations be

150 d resistant strains, and they were selective over other bacterial species and eukaryotic cells, metab

151 enable specific diagnosis of ZIKV infection over other flaviviral infections.

152 atforms, exhibited high specificity for crab over other types of crustaceans, and yielded much higher

153 ion studies of local adaptation combine data over populations.

154 0.94) in ARF prediction improved performance over preoperative features (AUC = 0.72; 95% CI: 0.50-0.8

155 otherwise leptosperin was chemically stable over prolonged storage at 37 degrees C.

156 urons can last a lifetime, but proteins turn over rapidly.

157 determine whether treatment effects cumulate over repeated intervention periods.

158 al fibrin(ogen) deposition was significantly over-represented in MS compared to control cases in all

159 Online double-pulse TMS over rTPJ 300 ms (but not 50 ms) after target appearance

160 This drift over several micrometers is reversible and can be contro

161 tons s(-1) mum(-2) ) in a natural scene vary over several orders of magnitude from shady woods to dir

162 er bilateral internal thoracic artery (BITA) over single left internal thoracic artery (SITA).

163 cash or voucher amount was given every month over six consecutive months.

164 Over six generations, invasions with any amount of genet

165 l data stay within these physical boundaries over six orders of magnitude of body mass regardless of

166 viewed as ecological disturbances exhibited over space on the microbiome continuum in a groundwater-

167 egration of the relevant retinal information over space.

168 ufficient evidence exists to support its use over standard clinical care.

169 s to pattern transitions from actin vortices over stars into asters.

170 Other hotspots of smoke occurrence are found over state and national parks in the southeast during wi

171 itions over large areas, with key advantages over strategies based on liquid phase (fusion) sintering

172 Results over synthetic models and models generated from Genomics

173 ine HCl(aq) and pyridoxine HCl(aq) solutions over temperature range (288.15-318.15)K at pressure, p=0

174 tralian humpback dolphins (Sousa sahulensis) over ten years of observation.

175 The nonequilibrium transport persisted over tens of picoseconds and 600 nanometers before reac

176 s observed extending 1-2 orders of magnitude over that of a reference TiO2 film.

177 Over the 15 years, EVI decreased significantly in Jamaic

178 substrate preference toward phosphinothricin over the 20 proteinogenic amino acids (1) , indirect eff

179 h averaged ground-level PM2.5 concentrations over the conterminous United States in 2011.

180 m Baptist Cancer Center (Memphis, Tennessee) over the course of 9 years (January 2004-December 2012).

181 ree eyes of 44 children had 339 OCT sessions over the course of clinical management (median number of

182 dynamics among tissues and cell populations over the course of infection.

183 ortance of particular routes also fluctuates over the course of the year, with increased travel from

184 tegrates external signals and exerts control over the decision between self-renewal and differentiati

185 ommodate changes in the modulatory structure over the duration of the experiment, and thereby discove

186 e tracking of the evolution of these neurons over the entire course of study.

187 Over the entire dose range, there are negative mortality

188 and consequently provides an image in focus over the entire field of view without any beam scanning

189 ility to interact with almost equal facility over the entire range of pi systems studied, with the si

190 n and outgassing behavior with no-hysteresis over the entire temperature and water activity range con

191 eed of sound increased from 1514 to 1532 m/s over the first 24 h, after which time it plateaued.

192 As debates continue over the functional significance of many specific lncRNA

193 agnetic stimulation for approximately 30 min over the hand representation of the motor cortex at an i

194 eling of mesoscale deep convection is tested over the Indian monsoon region (IMR).

195 Over the last 2 decades, research has unequivocally show

196 genetic variation, and the rate of evolution over the last 40 million years.

197 advanced their breeding phenology by 5-12 d over the last century.

198 ng of PSMA has become increasingly important over the last decade.

199 cute pancreatitis (HTG-AP) increased rapidly over the last decade.

200 Over the last few years, several groups have evaluated t

201 ulation has been on an extraordinary journey over the last three decades.

202 diovascular events did not markedly decrease over the last two decades.

203 but the ranges of transient species expanded over the long-term, slowly increasing their regional ret

204 mation of sultines was kinetically preferred over the loss of sulfur dioxide leading to o-quinodimeth

205 on loss engineering to achieve more control over the mode selectivity by suppressing the mode that h

206 l-interglacial timescales, but its existence over the most recent past remains unclear.

207 car elements and vessels entered the lesions over the next 7 d, as did large numbers of axons that we

208 icting behaviors and describe the challenges over the next few years.

209 Specifically, the posterior P2 component over the parieto-occipital lobe peaked significantly ear

210 Advances over the past 10 years have allowed large-scale assessme

211 Despite advances over the past 100 years, endophthalmitis is an important

212 nstruct the dynamics of the phosphorus cycle over the past 3.5 billion years, it remains uncertain wh

213 tion has become a standard-of-care procedure over the past 40 years.

214 ly increased in the United States and Canada over the past decade, largely attributable to a notable

215 mural dollars awarded to dental institutions over the past decade; however, given the year-to-year va

216 Methodological breakthroughs over the past four decades have repeatedly revolutionize

217 historical research of European developments over the past millennium suggests that such institutions

218 ncrease of 1.2 kgCm(-2) (c. 10%) in soil SOC over the period 1750-2010.

219 Maine, made from Halley Station, Antarctica, over the period 1971-2016.

220 ut little change is seen in nitrogen dioxide over the period from 1995 to 2015.

221 This would present a tremendous improvement over the present methods that excessively focus on detec

222 Intensive research over the previous decades has improved our understanding

223 eous protein surface and thus spatially vary over the protein surface.

224 mox did not differ in Rhode Island sediments over the seasonal cycle.

225 nt electrocatalysts by more rational control over the size, shape, composition, and structure.

226 or the enhanced activation of the cardiac TF over the skeletal TF by Ca(2+) and lead to a mechanistic

227 patial and temporal granularity in real-time over the skyline of Manhattan.

228 functional elements in order to gain control over the spatial and temporal elements of fundamental ce

229 ed or postponed and life-years gained (LYGs) over the study period, stratified by age, sex, and race.

230 ,000 confirmations for each of types A and B over the study period.

231 Adjusted mortality rates slightly declined over the study period.

232 he major contributor to actual eye movements over the tested stimulus range.

233 , advective transport of the combined liquid over the third wettable track.

234 ion between DNA fragmentation and sample age over the timespans analyzed, even when controlling for e

235 ate of microbial loads and air-sea exchanges over the tropical and subtropical oceans based on the da

236 Trusted decadal forecasts of UV dosage over the United States in summer require understanding t

237 Over the wide range of cardiac output produced by hemorr

238 ctions based on parent-collected nasal swabs over the winter months.

239 ), possibly due to competing causes of death over this dose interval.These results confirm and extend

240 in use following hospital discharge occurred over this period among patients initiating treatment (30

241 distributes, without additional plant uptake over this timescale.

242 of island dwarfing known thus far took place over thousands of years.

243 s suggest that experiences of active control over threat engage the striatum and promote a shift from

244 ella infections, with sensitivity decreasing over time (p=0.04).

245 ted with 73% increased odds of improving SMR over time [odds ratio (OR) 1.73; 95% confidence interval

246 f hepatitis B surface antigen (HBsAg) varies over time after cessation of nucleos(t)ide analog (NA) t

247 Investigating transformation over time along these dimensions will reveal how the nat

248 etween activity and movement was stable both over time and across VR environments.

249 Unspecified liver cancer decreased over time and constituted <10% of all reported liver can

250 tive mating was plastic, varying in strength over time and disappearing under manipulated conditions.

251 und healing, CD26-positive cells accumulated over time and persisted in forming hypertrophic-like sca

252 sa, the tripartite interaction was monitored over time and samples collected for scanning electron mi

253 used to investigate shifts in the microbiota over time and their associations with healing.

254 g over 40 years ago, hybridization increased over time at half (50%) of the locations with long-term

255 between known factors and spending increases over time could inform policy efforts to contain future

256 e, we report that TIGIT expression increased over time despite early initiation of ART.

257 r 3 weeks of diabetes, and these accumulated over time in addition to increased urine secretion of 8-

258 England and Wales and Scotland, and changes over time in Scotland.

259 weight-for-length), accompanied by declines over time in seasonal variability.

260 randomization, parasite prevalence increased over time in the STOP-CTX arm, compared with the CTX arm

261 We compared changes over time in the use of assisted ventilation and oxygen

262 NIFICANCE STATEMENT Combining sensory inputs over time is fundamental to seeing.

263 evolve independently, accumulating mutations over time that make them incompatible with one another.

264 Changes over time were correlated with disease progression using

265 ponding for cocaine, an effect that persists over time, across multiple contexts, and depends on acti

266 changes in location and appearance of SSPiM over time, and replication of SSPiM OCTA signal in an in

267 P-9 and an accumulation of cytoplasmic MMP-2 over time, but no significant MMP-3 or MMP-8 production

268 cids, glycerophospholipids and carbohydrates over time, induced by endothelial cell contact.

269 hydrogels allowed a higher retention of Dex over time, resulting in significantly increased alkaline

270 By tracking the same cell or group of cells over time, this method offers an avenue to understand dy

271 ildren were killed in increasing proportions over time, ultimately comprising a quarter of civilian d

272 subscales, respectively, and remained stable over time.

273 to the monitoring of its degradation profile over time.

274 We analysed deaths by governorate and over time.

275 d to examine trends in rates of sudden death over time.

276 solid waste incineration landfill leachates over time.

277 assessed risk factors or symptom progression over time.

278 ty and low release of encapsulated compounds over time.

279 ductivity and ocean-atmosphere oxygen levels over time.

280 nclusion pathology that increased and spread over time.

281 show increases in the rate of first records over time.

282 nd screening uptake by ethnicity in England, over time.

283 d insecurity and changes in body composition over time.

284 trends in icidence of bloodstream infection over time.

285 Changes-over-time temperature, blood pressure, and heart rate ou

286 anol, as well as the reactions of CO and CO2 over TMC surfaces.

287 ] of 45 initially administered D who crossed over to D + T).

288 % vs. 20%; P= 0.95) and lower rates of cross-over to resection (5% vs 11%; P< 0.0001) and development

289 Slow toxicodynamic recovery caused carry-over toxicity in subsequent exposures, thereby resulting

290 copy offers a significant gain in resolution over traditional optical microscopy, enabling the locali

291 olutionary forces of rigidity and plasticity over transcriptional regulatory programs.

292 de of interaction can allow TrkA selectivity over TrkB and TrkC or promiscuous, pan-Trk inhibition.

293 ied with or without Limus were also measured over two maize growing seasons.

294 esponse of precipitation to external changes over typical basins.

295 hat vanadium (V) is preferentially extracted over U and many other cations.

296 Over up to 15 years of follow-up in the Bruneck Study, m

297 ated the clinical benefits of nepafenac 0.3% over vehicle in reducing the risk of postoperative ME, w

298 getic costs, trans-Gulf migrants should stop over when they encounter crosswinds or headwinds, and de

299 omolecules, we demonstrate that the distance over which molecular junctions are maintained is a measu

300 istidine site is thermodynamically preferred over Zn(II).