ライフサイエンスコーパス: overdominant

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1 developed to predict the number of strongly overdominant alleles in a population of which the size v

2 ygous with other pl alleles; illustrating an overdominant allelic relationship.

3 ve, and we find statistical support for both overdominant and recombinant contributions to hybrid vig

4 nant contributions to heterosis to outnumber overdominant, and extensive pleiotropy.

5 We report a hitherto unknown overdominant effect (allelic interaction) at this locus,

6 surrounding CHRNA4 region, supporting a true overdominant effect at rs1044396.

7 This inverted U-shaped relation reflects an overdominant effect; that is, allelic interaction (cumul

8 amples that have both classical dominant and overdominant effects.

9 ex than predicted from classical dominant or overdominant explanations of heterosis.

10 due to resistance being dominant rather than overdominant, i.e., heterozygotes were more resistant th

11 0.35-0.95; P < 0.05) under the recessive and overdominant inheritance models, respectively.

12 seven chromosomal segments were linked to an overdominant lethal factor.

13 Overdominant or pseudo-overdominant lethal factors are a common component of th

14 ross the genome, but it is not clear whether overdominant lethal factors are rare or representative.

15 y occur within the embryo lethal system, (2) overdominant lethal factors are rarely detected because

16 t and display stage-specific expression, (3) overdominant lethal factors are rarely detected due to t

17 verdominance lethal factors were tested: (1) overdominant lethal factors rarely occur within the embr

18 Four overdominant lethal factors were linked to common and ra

19 both rs3217318 and rs10415893, following an overdominant model.

20 ions to heterosis and genetic variation from overdominant mutations are monotonic but not linearly pr

21 oefficient), biased downward when additional overdominant mutations are present.

22 gely on the magnitude of the contribution of overdominant mutations to heterosis or genetic variation

23 Overdominant or pseudo-overdominant lethal factors are a

24 quilibrium exists, (2) polymorphism requires overdominant or underdominant selection, and (3) a simpl

25 In numerical analyses, only overdominant polymorphic equilibria are stable, and thes

26 homozygotes, csd should be subject to strong overdominant selection and negative frequency-dependent

27 ure from neutrality is noted and no signs of overdominant selection are observed.

28 Further, we find that weak overdominant selection can increase, rather than decreas

29 se data suggest that directional rather than overdominant selection may predominate during periods of

30 is proposed for estimating the intensity of overdominant selection scaled by the effective populatio

31 leterious recessive alleles with selfing and overdominant selection with outcrossing can help explain

32 unt for this observation, these include: (1) overdominant selection, (2) fluctuating population size

33 is based on the assumption that, with strong overdominant selection, allele frequencies are nearly at

34 f V(H)1 polymorphism is apparently caused by overdominant selection, though the real mechanism is unc

35 ing to an additive, dominant, recessive, and overdominant trait model as well as a genotypic model wi

36 netic models such as recessive, dominant, or overdominant were considered only by very few studies.

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