ライフサイエンスコーパス: overexpression

1 n pathway, and that can be overcome by miR-7 overexpression.

2 c release, and occludes the effect of SENP3 overexpression.

3 ells, a process partially prevented by MCL-1 overexpression.

4 e activity could be easily saturated by Ser5 overexpression.

5 ariants but do not cure [PSI(+)], even after overexpression.

6 gans following hormetic heat stress or HSF-1 overexpression.

7 istic short-root phenotype caused by AtRALF1 overexpression.

8 sirt2 RNAi also phenocopies mir-92a overexpression.

9 partially reversed beneficial effects of SPL overexpression.

10 n effects opposite to those observed for SPL overexpression.

11 other aggressive tumors characterized by MYC overexpression.

12 sensitivity of glial cells to Pico/Ras(V12) overexpression.

13 on; and EGFR activity was insensitive to Cbl overexpression.

14 y promoted OC differentiation than did c-Fos overexpression.

15 mals exposed to hormetic heat shock or HSF-1 overexpression.

16 cannot be entirely compensated for by RUNX1B overexpression.

17 matically affected by mitochondrial ferritin overexpression.

18 death, both of which were mitigated by ATF6 overexpression.

19 n response to chronic mutant alpha-synuclein overexpression.

20 Pancreatic Ngf overexpression accelerated tumor development in LSL-Kras

21 Here, we tested whether hippocampal FKBP1b overexpression also counteracts aging changes in gene tr

22 CXCR4 overexpression also increased miR-15a/16-1, shifting the

23 VMH Trx-1 overexpression also lowered the insulin requirement to p

24 during puberty, it is not clear whether its overexpression alters normal mammary development in vivo

25 tively, these findings demonstrated that Lyn overexpression ameliorated airway mucus hypersecretion b

26 ng and AMPK-inhibition abrogated, while LKB1-overexpression and AMPK-activation potentiated HNK's eff

27 combination of simulation experiments of Ras overexpression and catalase knockout in conjunction with

28 TWIST1 overexpression and DNM3OS amplification provides an expl

29 that reactivation of MAPK signaling via CRAF overexpression and dysregulation is a mechanism for vemu

30 IL-6 signaling was increased by Gab2 overexpression and impaired by Gab2 deletion via regulat

31 IDL6 overexpression and knockdown lines respectively decrease

32 3 knockout in mice (Gja1 (adipoq) KO) and by overexpression and knockdown of Cx43 in cultured adipocy

33 erichia coli We optimized conditions for the overexpression and membrane solubilization of an MsrQ-GF

34 Overexpression and mutations of EGFRs, or aberrant EGFR

35 rrents in the mPFC were prevented by PKMzeta overexpression and potentiated by PKMzeta inhibition in

36 In blood cancers, the synergism between HIF overexpression and stabilization within the hypoxic BM m

37 Transgenic overexpression and suppression of PtabZIP1L also resulte

38 The effects of AURKA overexpression associated with poor clinical outcomes ha

39 maturation of plasmatocytes, whereas Tiggrin overexpression blocks this process, resulting in a build

40 id leukemogenesis in the context of Hox gene overexpression but is currently considered undruggable.

41 Overexpression, but not knockdown of HRS, promoted hyper

42 In mice, HO-1 overexpression by genetically modified HO-1 macrophage t

43 HSJ1 overexpression can reduce aggregation of neurodegenerati

44 inistration or virally mediated hypothalamic overexpression converts them to a 'female-like' metaboli

45 ASXL3 overexpression correlated with increased genomic copy nu

46 of ovarian cancer cell lines and that MICU1 overexpression correlates with poor overall survival (OS

47 g a variety of manipulations, including gene overexpression, CRISPR/Cas9 gene editing, inducible tech

48 However, like NAC, VMH Trx-1 overexpression did not prevent HAAF or normalize activat

49 MRTF overexpression drove the TAZ promoter in a CC(A/T-rich)6

50 Chmp4) to repress Shrub expression, causing overexpression during the disease state early-use critic

51 Moreover, FGF13 overexpression enables cells to cope more effectively wi

52 MASP1 overexpression enhanced growth, in vivo microtubule stab

53 t3(ITD) share a number of features: Hox gene overexpression, enhanced self-renewal, expansion of hema

54 These data suggest that MIOX overexpression exacerbates, whereas MIOX gene disruption

55 chemical inhibition, genetic depletion, and overexpression experiments, we show that casein kinase 2

56 lly associated with MYC amplification and/or overexpression, frequent metastasis and a dismal prognos

57 Conversely, Wnt1 overexpression from osteocytes stimulated bone formation

58 MiR-181b-1 ectopic overexpression further diminishes Bcl-2 expression leadi

59 MSI1 overexpression has been observed in several tumor tissue

60 h miRNA and AUF1 are less abundant upon AUF1 overexpression implying that AUF1 is a decay-promoting f

61 Meg3 overexpression in a mouse insulin-secreting PNET cell li

62 c and therapeutic value of identifying AGTR1 overexpression in a subset of HER2-negative breast cance

63 Supporting these data, ACA11 overexpression in a t(4;14)-negative MM cell line, MM1.S

64 Mechanistically, RARRES2 overexpression in ACC cells inhibited Wnt/beta-catenin p

65 heat-shock factor-1 by knockdown in nCPCs or overexpression in aCPCs significantly altered the qualit

66 Cav-1 overexpression in adult mice enhanced dendritic arboriza

67 MYC overexpression in B-NHL is associated with more aggressi

68 RAGE ectopic overexpression in breast cancer cells increased MEK-EMT

69 In vivo experimental studies show that LOX overexpression in colorectal cancer cells or systemic de

70 is preliminary study demonstrates that sFRP1 overexpression in gastric cancer cells leads to increase

71 reover, we found that Gsx2 and Ebf1 combined overexpression in hES cells achieves high yields of MSNs

72 SOX11 overexpression in mantle cell lymphoma (MCL) has been as

73 ons in experimental design, such as receptor overexpression in myocytes that do not express the AR no

74 BMP4 overexpression in non-osteogenic C4-2b PCa cells led to

75 In a PTEN-null murine PCa model, WHSC1 overexpression in prostate epithelium cooperated with Pt

76 ciated with survival and showed longitudinal overexpression in subjects experiencing disease progress

77 essfully in immunocompromised mice, but IDH1 overexpression in these cells was sufficient to fully re

78 equencing to investigate the effect of E2f3a overexpression in this region on gene expression and alt

79 mation, and mucus production, and transgenic overexpression in WT mice exacerbates these phenotypes.

80 GOT overexpression increased anaplerotic refilling of tricar

81 P6V1A mRNA and protein expression, while YY1 overexpression increased ATP6V1A expression level.

82 As expected, CD14 overexpression increased barrier integrity.

83 Tomo-1 overexpression increased dendritic spine density, wherea

84 We found that Msx gene overexpression increased expression of specific blastema

85 We showed that hAS overexpression increased levels of aldosterone in hAS(+/

86 ptor alpha (PPARalpha) target genes, whereas overexpression increased PPARalpha reporter activity, su

87 IF-2alpha or Yes-associated protein 1 (YAP1) overexpression indicates a significant overlap of genes

88 vivo as a consequence of the transient CD44 overexpression induced by HA.

89 an antioxidant reagent, rescued HDG and PLK2 overexpression-induced kidney injuries.

90 HDAC3 overexpression inhibited Sp1-mediated Aqp5 activation, w

91 In addition, miR-542-3p overexpression inhibited the morphological transformatio

92 Moreover, miR-26a overexpression inhibits the tumor cell growth both in vi

93 tissue stem cells of many epithelia, and its overexpression is negatively correlated with cancer prog

94 In our human cell models, TRAP1 overexpression is protective, rescuing HTRA2 and PINK1-a

95 data show that in pre-malignant B cells, Myc overexpression is sufficient to activate BCR and PI3K/Ak

96 t on radiation-induced EndoMT in vitro, Hey2 overexpression is sufficient to induce phenotypic conver

97 Its overexpression is sufficient to reduce VSMCs proliferati

98 Results from our analysis showed that Pak1 overexpression, knockdown and Pak1 knockout cell line mo

99 TWIST1 overexpression led to coenrichment of TWIST1 and WDR5 as

100 Msh3 overexpression led to high expansion activity and elevat

101 TOR overexpression lines displayed increased susceptibility

102 Knockdown and overexpression lines of HER2 confirmed the role of HER2,

103 y overexpression of either BGLC1 or BGLC3 In overexpression lines, BGLC3 activity was concentrated in

104 incorporated into TAG in both wild-type and overexpression lines, indicating a significant flux of n

105 RB8 in HR is further supported by amiRNA and overexpression lines.

106 ream glycerolipid metabolism pathway in GPD3 overexpression lines.

107 ated that inducible lentiviral-mediated ChR2 overexpression might cause cytotoxicity in NRVM cultures

108 We therefore hypothesized that C/EBPalpha overexpression might rescue osteoclastogenesis in cells

109 Consistently, C/EBPalpha overexpression more strongly promoted OC differentiation

110 cause resistance to APYS1, however, neither overexpression nor conditional depletion of wag31 impact

111 Inhibiting protein phosphatase-1 through the overexpression of a constitutively active inhibitor-1 (I

112 Here, we show that overexpression of a dominant-negative version of DA1 enh

113 were conducive to nematode infection because overexpression of a noncleavable coding sequence of MYB8

114 Overexpression of a phosphorylation mimetic (S226D) in y

115 Overexpression of a specific subset of Rab GTPase-activa

116 Lethal overexpression of actin results from mating this enginee

117 ost of these models have employed transgenic overexpression of alanine-expanded PABPN1.

118 Overexpression of anti-apoptotic BCL-2 proteins contribu

119 After overexpression of arylalkylamine N-acetyltransferase (AA

120 Here we show that MG-specific overexpression of Ascl1, together with a histone deacety

121 Conversely, overexpression of Ascl2 inhibits the proliferation and d

122 nditional genetic deletion and/or transgenic overexpression of ATX established a liver profibrotic ro

123 hronic lymphocytic leukemia (CLL), promoting overexpression of BCL2, which factors in leukemia pathog

124 Importantly, hepatocyte-specific overexpression of beta-arrestin 2 greatly reduced hepati

125 Overexpression of betaTrCP2 or the knockdown of Cdc25A r

126 Overexpression of cathepsin B resulted in decreased OA u

127 Neuron-targeted overexpression of Cav-1 in the adult and aged hippocampu

128 Our findings suggest that overexpression of cel-mir-237 and its homolog, hsa-miR-1

129 Our results suggest that overexpression of cell-cycle-related genes are a charact

130 We confirm the concurrent overexpression of cIAP1 and cIAP2 and observe differenti

131 ere, we provide mechanistic insight into how overexpression of CKS proteins promotes override of the

132 Overexpression of COL12 also affects plant architecture

133 Overexpression of COL12 causes late flowering specifical

134 Overexpression of constitutively active SHP2 reduced the

135 Although overexpression of CRABP2 is described in several cancers

136 In this study, the effect of the overexpression of CXCL13 on the immunogenicity of the RA

137 Conversely, overexpression of CYP4A or exogenous addition of 20-hydr

138 ts were blocked by treatment with Na2S or by overexpression of cystathionine gamma-lyase (CSE).

139 Furthermore, overexpression of dihydrolipoyl succinyltransferase (DLS

140 Moreover, overexpression of DLST in wild-type mice protected again

141 and fresh frozen tissues, we found that the overexpression of DNMT1 is positively correlated with th

142 We found that overexpression of dominant-negative (DN) forms of NSF or

143 ver-specific knockout or adenovirus-mediated overexpression of DsbA-L exacerbates or alleviates, resp

144 suffer from low throughput, modification or overexpression of effector proteins, and low temporal re

145 In addition, bglc1 bglc3 was complemented by overexpression of either BGLC1 or BGLC3 In overexpressio

146 Overexpression of either LPEAT1 or LPEAT2 under the cont

147 In living cells, overexpression of endophilin delayed both fission and tr

148 true NEDD8 targets has been challenging, as overexpression of exogenous NEDD8 can trigger NEDD8 conj

149 Overexpression of Fgf16 in vivo recapitulated several of

150 dlBST indeed displayed an overexpression of FosB, ARC, Zif268 and FRA2 only in dys

151 Overexpression of FoxO in wild type cardiomyocytes induc

152 ength when overexpressed in Arabidopsis, the overexpression of full-length OsbZIP48 in rice transgeni

153 Overexpression of functional NMDAR in non-neuronal cells

154 d induced cardiomyocyte-like cells (iCMs) by overexpression of Gata4, Mef2c, and Tbx5 (GMT) using ret

155 Intriguingly, transgenic overexpression of GCH1 in cardiomyocytes reduces the thi

156 Moreover, we show that overexpression of GOF mutant p53 G245D decreases the AMP

157 Overexpression of HBL1 repressed, whereas knockdown and

158 Overexpression of HER2 has been reported in around 25% o

159 xic inflamed tissues are associated with the overexpression of HIFs, specific inhibition of HIFs migh

160 We then investigated the effect of overexpression of human alpha-synuclein in the substanti

161 Overexpression of human MYCN in the context of Rb inacti

162 Overexpression of IFI16 also suppressed DeltaICP0 virus

163 ion of downstream transcription factors, and overexpression of IFN-beta mRNA and protein were similar

164 ic, but not eosinophilic, asthmatics display overexpression of IFN-beta, IFN-lambda1/IL-29 and ISGs i

165 o distinct mechanisms were implicated in the overexpression of IFN-beta: first, JNK-mediated activati

166 novel evidence that CTCF depletion leads to overexpression of inflammation-related genes and microgl

167 The heterologous overexpression of integral membrane proteins in Escheric

168 The first is that overexpression of iron regulatory protein 2 (IRP2) recap

169 er types by mutations in the TP53 gene or by overexpression of its negative regulators, oncoproteins

170 Overexpression of KCNQ1 trapped beta-catenin at the plas

171 ly rescued by endothelial cell (EC)-specific overexpression of Kir2.1.

172 Overexpression of Kv1.1 was sufficient to enable dendrit

173 However, achievement of the overexpression of membrane proteins is not necessarily s

174 Overexpression of microRNA-146a in cardiomyocytes provok

175 Overexpression of miR-10b increased Ki-67 staining in hu

176 ermore, like stable Pin1 knockdown, moderate overexpression of miR-140-5p not only eliminates Pin1, b

177 es, JAM-A and FSCN1, were downregulated with overexpression of miR-143 and miR-145.

178 Finally, we provide evidence that overexpression of miR-183, the human ortholog of miR-263

179 human prostate cancer cell lines, and stable overexpression of miR-194 enhanced metastasis of intrave

180 Lentiviral overexpression of miR-26a in ZOS and 143B osteosarcoma c

181 Conversely, overexpression of miR-29 by electroporation of mouse tib

182 Conversely, overexpression of miR-31-3p ameliorated the severity of

183 Conversely, transgenic overexpression of miR-497 approximately 195 in murine en

184 l microRNA that regulates Bcan is miR-9, and overexpression of miR-9 can partly rescue the effects of

185 Overexpression of miR156 induced aerial bud formation in

186 ents are reportedly achlorhydric, transgenic overexpression of ML1 in mouse parietal cells induced co

187 r overexpressed in 15% of breast tumors, and overexpression of MYST3 correlated with worse clinical o

188 These reagents were used to examine whether overexpression of NC1 domain with high transfection effi

189 ion that are partially rescued by concurrent overexpression of Nedd4.

190 agreement with this observation, the induced overexpression of NEK6 reduced and disorganized cortical

191 The overexpression of nfnB resulted in sensitivity of M. sme

192 PAX3-mediated transcriptional repression and overexpression of NNMT blocked tumor cell invasion in vi

193 protection was not observed, whereas ectopic overexpression of Notch1 diminished TNFalpha-induced apo

194 Overexpression of NRF-1 increased TDP1-promoter activity

195 ion of ZFP804A decreases NRGN expression and overexpression of NRGN can ameliorate ZFP804A-mediated m

196 Overexpression of NRP2 or its N-terminal domain enhances

197 g gain-of-function approaches, we found that overexpression of Ntn1 in the chick otic vesicle prevent

198 elial electrical resistance [TEER]), whereas overexpression of p120 increases VE-Cad levels and promo

199 errations in thyroidal TPC-1 cells following overexpression of PBF and PTTG.

200 tumor cells, which was partially reversed by overexpression of PcG member BMI-1, suggesting opposing

201 arly, administration of either GSK2656157 or overexpression of PERK-K618A in primary neurons rescues

202 f PGX3 prevents smooth stomatal closure, and overexpression of PGX3 accelerates stomatal opening.

203 Overexpression of PinX1 reduced the level of EV71-induce

204 Conversely, overexpression of PLCgamma1 both reduces the motivation

205 and [5-InsP7] were restored to WT levels by overexpression of PPIP5K1, and a kinase-compromised PPIP

206 Overexpression of prolyl-hydroxylase 2 (PHD2) transgene,

207 transient apoptosis inhibition by short-term overexpression of prosurvival BCL-XL, known to block BIM

208 ssociated virus serotype 9)-mediated cardiac overexpression of Qki5 prevented cardiac apoptosis and c

209 ein synthesis, an effect which is rescued by overexpression of RACK1.

210 nhibition resulting from RCAN1 upregulation, overexpression of RCAN1 in naive DRG neurons recapitulat

211 In conclusion, our findings suggested that overexpression of RGC32 facilitates EMT of CRC cells by

212 he purpose of this study was to determine if overexpression of SAP2 or SAP5 in an efg1Delta/Delta cph

213 and qRT-PCR expression analysis showed that overexpression of SeCsp could enhance the expression of

214 these CYP-derived metabolites by transgenic overexpression of sEH, the protective effect against CNV

215 Indeed, stable overexpression of select IQD proteins in Arabidopsis alt

216 Notably, we detected hypomethylation and overexpression of several pro-inflammatory genes such as

217 ning in kidney biopsy specimens demonstrated overexpression of ShcA in several human proteinuric kidn

218 stress via upregulation of miR-204, whereas overexpression of Sirt1 in endothelial cells suppresses

219 Overexpression of Skp2 coupled with underexpression of p

220 LP-2, and further, tissue-specific or global overexpression of SLP-2 transgenes rescued parkin mutant

221 Overexpression of Sm proteins under these conditions res

222 nitive deficits of ASD and ID in humans, and overexpression of small 22q11.2 segments recapitulates d

223 Overexpression of SOCS3 strongly inhibited phosphorylati

224 of cell survival and of lipid synthesis, as overexpression of SREBP-1 rescues lipogenic defects asso

225 Conversely, cellular overexpression of STUB1 resulted in reduced phosphorylat

226 Underlying mechanisms likely include overexpression of SULTR1;2 and SULTR2;1, which may addit

227 ss-cytometry-based single-cell analysis with overexpression of tagged signaling proteins to study the

228 his difference appears to be important since overexpression of the abrB gene in SM101 reduced the lev

229 Overexpression of the adenosine diphosphoribose insensit

230 red expression in aneuploid cells, including overexpression of the cellular prion protein CD230/PrP(C

231 Overexpression of the EVI1 oncogene is associated typica

232 Because overexpression of the gastrin-releasing peptide receptor

233 ber variation of the UBE3A gene and aberrant overexpression of the gene product E6AP protein is a com

234 for the wild-type system, but indicates that overexpression of the LacI repressor would drive the sys

235 Overexpression of the miR-183 cluster reduced zinc trans

236 35 enhancer and promoter elements along with overexpression of the MIR355 gene after adipogenic induc

237 In this study, we report overexpression of the nuclear receptor NR4A1 in rhabdomy

238 Previous studies have suggested that overexpression of the oncogenic protein epithelial membr

239 We note that overexpression of the proteins is toxic to M. smegmatis,

240 ion of autophagy and lysosomal exocytosis by overexpression of the transcription factor EB (TFEB) gen

241 Overexpression of the transcriptional coregulators C-ter

242 Interestingly, overexpression of the wild-type PDGFRA was even more pot

243 Notably, overexpression of the wild-type PRKACA was unable to ful

244 However, the mechanisms driving overexpression of this receptor in cancer are poorly und

245 cardiomyopathy driven by cardiac restricted overexpression of TNF (tumor necrosis factor; Myh6-sTNF)

246 Reciprocally, overexpression of Tnni3k in zebrafish promoted cardiomyo

247 model of chronic lung disease induced by the overexpression of transforming growth factor-alpha (TGF-

248 Here we define the overexpression of transient receptor potential vanilloid

249 cancer cell lines with pronounced endogenous overexpression of TRPV4, MDA-MB-468 and HCC1569.

250 e plant architecture originated from ectopic overexpression of tru1 in axillary branches, a critical

251 These effects were rescued by overexpression of TSG101.

252 isplatin and PARP inhibitor (olaparib) while overexpression of USP13 renders ovarian cancer cells res

253 Overexpression of USP28 largely reversed HDAC5-KD-induce

254 at tightening of ER-mitochondria contacts by overexpression of VAPB or PTPIP51 impairs rapamycin- and

255 Finally, we showed that overexpression of wild type and mutant 4R-Tau isoform in

256 Conversely, overexpression of wild-type METTL3, but not of a catalyt

257 on in other cancers and major impact of Pin1 overexpression on activating numerous cancer-driving pat

258 GRP78 reversed the attenuating effect of ECD overexpression on PERK signaling.

259 We analyzed the effects of SH2 domain overexpression on protein tyrosine phosphorylation by qu

260 ctivity decreased significantly during SIRT1 overexpression or activation by resveratrol.

261 However, overexpression or downregulation of these microRNAs caus

262 We showed that E2f3a, but not E2f3b, overexpression or knockdown in mouse NAc regulates cocai

263 Toward this end, we tested whether NLRC3 overexpression or knockdown influences NALP3 activity in

264 Here we show for the first time that overexpression or knockdown of RanBP9 directly enhances

265 educed by Hsp90 or Hsc70 inhibitors, whereas overexpression or knockdown of RanBP9 significantly dimi

266 at downstream targets in NAc following E2f3a overexpression or repeated cocaine exposure.

267 It has been shown that CKS protein overexpression overrides the replication stress checkpoi

268 Importantly, BRCA2 overexpression partially restores the USP21-associated s

269 in Fgfr1/Fgfr3 double mutant mice, while HK2 overexpression partly rescues the defects caused by supp

270 II complexes also was seen in the Rieske FeS overexpression plants.

271 oxidation is negatively regulated by miR-29 overexpression, potentially through the regulation of pe

272 lly decreased lung metastasis, whereas LOXL2 overexpression promoted metastatic tumor growth.

273 We also demonstrated that RGC32 overexpression promoted proliferation, migration and tum

274 In vivo, LDHA overexpression promoted tumor growth, and oxamate delaye

275 Notably, gene therapy-mediated PINK1 overexpression promotes the clearance of damaged mitocho

276 In human myotubes, ACSL6 overexpression reduced palmitate oxidation and PGC-1alph

277 ectin and VCAM1, respectively, while miR-126 overexpression reduced VCAM1 and CCL2 expression by hCME

278 We found that TCF19 overexpression represses de novo glucose production in H

279 epletion reduced HR and enhanced NHEJ, Mcl-1 overexpression resulted in a net increase in HR over NHE

280 We found that SH2 overexpression results in a significant, dose-dependent

281 Additionally, P2Y14 R overexpression reversed senescence-associated morphology

282 Consistently, we found FMRP loss and Shrub overexpression similarly elevate endosomes and result in

283 In vitro, hnRNP F overexpression stimulated Sirtuin-1 and Foxo3alpha with

284 iverse array of human cancer cells that IMP2 overexpression stimulates and IMP2 elimination diminishe

285 e secondary metabolites of xpp1 deletion and overexpression strains using an untargeted metabolomics

286 Here we use overexpression studies, mutagenesis, and flow cytometry

287 Furthermore, we demonstrated that E2f3a overexpression substantially recapitulates genome-wide t

288 tl4(-/-) mice and increase following Angptl4 overexpression suggest that changes in plasma triglyceri

289 cordance with that triggered by gga-miR-219b overexpression, suggesting that BCL11B was a stimulative

290 matic NF-kappaB pathway aberrations and LMP1-overexpression, suggesting that NF-kappaB activation is

291 We show that GLI2 overexpression supported long-term epidermal regeneratio

292 fic ablation of Akt3/-S472 enhanced, whereas overexpression, suppressed mammary tumor growth, consist

293 We report that transgenic FOXC1 overexpression suppresses lobuloalveologenesis and lacta

294 We here show by mutation and overexpression that Doc2B plays distinct roles in two se

295 In addition, CYCD3;1 overexpression upregulates immune responses, and SNC1 ex

296 nducible degrader of the LDL receptor (IDOL) overexpression, using liver-targeted adenoassociated vir

297 ncreased growth of MDA-MB-231 cells by HDAC5 overexpression was reversed by concurrent LSD1 depletion

298 analysis of endothelial cells after miR-100 overexpression, we identified miR-100 as a potent suppre

299 The angiogenic up-regulation of sFRP1 overexpression were further verified with in vitro cell

300 mplification events, and associated receptor overexpression, would be adaptive during glioma evolutio