ライフサイエンスコーパス: overrepresentation

1 hat displays the distribution of the motif's overrepresentation across loop geometries, enabling the

2 Gene set enrichment analysis and overrepresentation analyses are commonly used methods to

3 ltered pathways/processes were identified by overrepresentation analyses of changed genes.

4 nistic insights into the underlying biology, overrepresentation analysis (ORA) is often conducted to

5 Pathway overrepresentation analysis and functional network analy

6 Overrepresentation analysis indicated that SP cells are

7 Overrepresentation analysis of growth-correlated genes p

8 ls enable ID mapping, pathway assignment and overrepresentation analysis of user-supplied data sets.

9 bioinformatic analyses (Gene Ontology terms overrepresentation analysis, hierarchical clustering, an

10 Based on overrepresentation analysis, several predominant biologi

11 idering signalling pathway topology, and the overrepresentation and magnitude of differentially-expre

12 e sensitive NestedMICA algorithm, as well as overrepresentation and pairwise motif matching capabilit

13 x1 gene dosage, 4.7% show Six1 amplification/overrepresentation, and tumors that exhibit an increase

14 These data implicate Six1 gene amplification/overrepresentation as a mechanism of Six1 mRNA overexpre

15 es and 5,510 internal controls confirmed the overrepresentation as statistically significant and repl

16 rentiating noise from true position-specific overrepresentation at single-nucleotide resolution.

17 .g., glycine in methionine biosynthesis) and overrepresentations (e.g., tryptophan in asparagine bios

18 ed declarative memory system in favor of its overrepresentation in a cue-based sensory/emotional memo

19 binding sites for FOX TFs showed substantial overrepresentation in both advanced human and early muri

20 l clustering in the genomes studied, and (v) overrepresentation in expressed sequences from reproduct

21 Their marked overrepresentation in genomes, and largely unchanging de

22 d with lambda-type myeloma may relate to its overrepresentation in molecularly defined high-risk dise

23 s cis-region, and (iii) exhibits a trend for overrepresentation in persons with reduced susceptibilit

24 The remarkable overrepresentation in the ATX1-regulated gene fraction o

25 ansion, associated with a lack of iTreg cell overrepresentation in the decidua.

26 rs among predicted domain interactions, this overrepresentation is significantly lower than in the iP

27 Significant Six1 gene amplification and overrepresentation occurs in numerous breast cancer cell

28 stage-specific functional analysis revealed overrepresentation of "cell wall," "stress," and "develo

29 t an HLA-dependent mechanism is suggested by overrepresentation of "protective" class I alleles, such

30 of inferred haplotypes for IL12A revealed an overrepresentation of -798T/277A in subjects with high H

31 Overrepresentation of 3'-terminal sequences among cDNAs

32 One tumor had overrepresentation of 7q31 without any apparent anomaly

33 vealed overall underrepresentation of 8p and overrepresentation of 8q.

34 We have recently reported that overrepresentation of 8q24 (c-myc) is associated with cl

35 onally active promoters and display striking overrepresentation of a consensus DNA sequence virtually

36 q data from cultured neurons, we find strong overrepresentation of a motif that matches our in vitro

37 AEI promoting the overrepresentation of a mutant allele might also play a

38 Overrepresentation of a single codon was typically plesi

39 0% vs. 77.8%, respectively; P=.037); and (4) overrepresentation of a specific PFGE genotype (85.7% vs

40 croarray data in ceh1 plants established the overrepresentation of a stress-responsive cis element an

41 We also found substantial overrepresentation of African-American patients among th

42 l eukaryotic genomes studied, we observed an overrepresentation of all repeats, especially homopurine

43 occal enzyme, staphylococcal LPXTGase has an overrepresentation of amino acids found in the peptidogl

44 Genetic analyses revealed an overrepresentation of antibiotic resistance genes.

45 amilies by DLBCL tumors was unbiased without overrepresentation of any particular V(H) gene or gene f

46 PRC1 complexes and requires a region with an overrepresentation of basic amino acids.

47 positional constraints, we investigated the overrepresentation of binding sites in the vicinity of o

48 We present a method for testing overrepresentation of biological pathways, indexed by ge

49 s dampened in the Apc(1638N/+) mice, with an overrepresentation of c-myc target genes among those loc

50 In comparison, an overrepresentation of cardinal orientations in the repre

51 The overrepresentation of cardinal tuned neurons was particu

52 This finding implies that overrepresentation of CD4(EM) cells is a unique feature

53 ve cells, apoptotic lymphocytes displayed an overrepresentation of CD45RO and HLA-DR expressing cells

54 The module of interest was characterized by overrepresentation of cell cycle-related genes (FDR = 3.

55 anscriptome analysis of nod mutants revealed overrepresentation of cell wall, hormone metabolism, and

56 However, there was a modest but significant overrepresentation of cells bearing Vbeta8 in the graft

57 onnectivity of cortical networks features an overrepresentation of certain wiring motifs compared to

58 initially were evolved to track the default overrepresentation of codons with preferred motifs.

59 MEK-ERK-regulated genes exhibited an overrepresentation of cognate sequences for the aryl hyd

60 Overrepresentation of conserved aromatic amino acids thr

61 Of particular note is the overrepresentation of conserved SCD-containing proteins

62 ter deficit of CpG dinucleotides, a stronger overrepresentation of CpG-containing n-mers surrounding

63 We identified a substantial overrepresentation of CPVT-associated variants in a larg

64 n cytogenetic subgroups of childhood ALL and overrepresentation of CRLF2-IL7R-JAK-STAT activating gen

65 d that exposure to adriamycin resulted in an overrepresentation of cytogenetic changes involving telo

66 nocturnal hemoglobinuria, a seemingly random overrepresentation of different V beta families was obse

67 that showed highly statistically significant overrepresentation of dimers formed by structurally simi

68 infected individuals are associated with the overrepresentation of distinct B cell populations.

69 ut not those of an NKX2-5 YRD mutant, showed overrepresentation of ETS binding sites and were occupie

70 using Unigene cluster data mining, we found overrepresentation of expressed sequence tags correspond

71 The overrepresentation of females and blacks in the group of

72 y a model of lateral inhibition based on the overrepresentation of frontal space observed in ICx.

73 le bioinformatics tools revealed significant overrepresentation of Gene Ontology clusters within hema

74 SNP, and an enrichment score reflecting the overrepresentation of gene-based association signals in

75 he WB discovery cohort, we found significant overrepresentation of genes associated with asthma contr

76 among the up-regulated genes, a significant overrepresentation of genes containing activation protei

77 Gene ontology analysis showed overrepresentation of genes involved in apoptosis among

78 The overrepresentation of genes involved in calcium homeosta

79 y sites of loss in CR metastases, we find an overrepresentation of genes involved in cellular lipid m

80 differentially expressed genes pointed to an overrepresentation of genes involved in G protein-couple

81 n, and chromosome function, demonstrating an overrepresentation of genes involved in mitotic regulati

82 ce of any exogenous genotoxic agent, with an overrepresentation of genes linked to cancer.

83 of differentially expressed genes showed the overrepresentation of genes potentially involved in flor

84 We show an overrepresentation of genes related to neuronal function

85 An overrepresentation of genes with known functions and gen

86 in metabolism and receptor/signaling, and an overrepresentation of genes with unassigned function (32

87 ary and Ingenuity Pathways Analysis revealed overrepresentation of GO categories related to developme

88 ed a Bayesian approach (GO-Bayes) to measure overrepresentation of GO terms that incorporates the GO

89 Regional differences included overrepresentation of graminoids in SA and AU and of ann

90 This was preceded by an overrepresentation of granulocytic cells in the bone mar

91 (IGF1R) genes of female centenarians showed overrepresentation of heterozygous mutations in the IGF1

92 es show different SFS; although both show an overrepresentation of high frequency derived sites, low

93 The results confirm previous findings of an overrepresentation of highly edited mRNA variants (which

94 We report overrepresentation of HLA-DR2 and its serologic split HL

95 There was an overrepresentation of homeobox genes and 31% of the most

96 ted from Hardy-Weinberg equilibrium, with an overrepresentation of homozygotes.

97 h HPV-associated tumours revealed a striking overrepresentation of homozygous arginine-72 p53 compare

98 Bioinformatic analysis showed an overrepresentation of hormone-nuclear receptors within t

99 one third of the whole cohort, including an overrepresentation of IGHV4-34 (15.5% overall).

100 w number of somatic mutations as well as the overrepresentation of IGHV5-51 among TG2-specific plasma

101 these Treg cells was subtly altered, with an overrepresentation of IRF4-dependent transcripts.

102 und with relatively lower GC composition and overrepresentation of IS elements, similar to the minich

103 pronounced in the decidua, where there is an overrepresentation of iTreg cells.

104 Overrepresentation of Jlambda distal cluster C genes rea

105 Many algorithms analyze enhancers for overrepresentation of known and novel motifs, with the g

106 etween cases (MCI and AD) and controls shows overrepresentation of large heterozygous deletions in ca

107 ificant impact on community structure due to overrepresentation of low-GC genomic regions following l

108 It contributed to the unexpected overrepresentation of male-biased genes on the autosomes

109 Gene ontology analysis revealed the overrepresentation of many transcription factors involve

110 In addition, a massive overrepresentation of members of the luciferase-like mon

111 to chromosome 11, suggesting a trend toward overrepresentation of methylation events on this chromos

112 not initiate randomly but with a significant overrepresentation of microtubules at diagonal angles wi

113 ects were mostly women (70.7%) and there was overrepresentation of minorities for unclear reasons.

114 led to eliminate the well-known X-chromosome overrepresentation of MR genes and candidate genes.

115 ion of MSI versus point mutations, including overrepresentation of MSI in euchromatic and intronic re

116 We further observed strong overrepresentation of multiple transcription factor bind

117 We employed bioinformatic analysis to find overrepresentation of noise-minimizing operon organizati

118 Hence, the significant overrepresentation of nonsyntenic genes among SPE patter

119 Mox phenotype was characterized by abundant overrepresentation of Nrf2-mediated expression of redox-

120 In this study, overrepresentation of one T-cell receptor beta chain var

121 Previous studies suggest overrepresentation of particular polymorphisms within th

122 abnormal expression of germline V segments, overrepresentation of particular sequences that correspo

123 Given the possibility of an overrepresentation of perioral tics in this group of hig

124 S is the most frequent presentation, with an overrepresentation of polymorphous ophthalmological symp

125 ansplant graft-versus-leukemia effect and an overrepresentation of poor prognostic factors in elderly

126 lular compartments was determined and showed overrepresentation of protein kinases.

127 ated with the alarm pheromone response shows overrepresentation of protein metabolism, regulation of

128 the binding partners revealed a significant overrepresentation of proteins involved in nucleotide me

129 There was a significant overrepresentation of proteins involving chromosomal fun

130 This excess was driven by the overrepresentation of QQ homozygotes in the mothers of c

131 f genes clustered by VxInsight identified an overrepresentation of Rap1p and BUF (RPA) binding sites

132 The results further suggest that overrepresentation of rare variants in a specific ethnic

133 an neutral reference genes, but there was no overrepresentation of regulatory genes in the selected g

134 Canonical pathway analysis identified overrepresentation of relevant pathways involved in regu

135 We determined that there was a significant overrepresentation of RNAs from introns and intergenic r

136 The overrepresentation of SCA transcripts in modules identif

137 We propose that the overrepresentation of secreted proteins as dominant targ

138 es in the phylogenetic tree with significant overrepresentation of sequences from a given source popu

139 sensitive to (1) local alignment errors, (2) overrepresentation of sequences in some branches and (3)

140 n colonic cells uncovered highly significant overrepresentation of sequences that bind TCF4, a transc

141 eable datasets and reduces sampling bias and overrepresentation of sequences.

142 We detected the overrepresentation of several genera such as YS2/Cyanoba

143 approach to analyze variants and identified overrepresentation of several pathways, including cytosk

144 tatistically significant (P = 6.41 x 10(-4)) overrepresentation of shared associations in development

145 The significant overrepresentation of similar groups of DEGs in the tran

146 th environmental and clinical ESBLEC and the overrepresentation of some clonal complexes.

147 ilico promoter analysis revealed significant overrepresentation of SP1/SP3-binding sites and/or GC-ri

148 We hypothesize that significant overrepresentation of specific gene ontology classes (e.

149 The observed overrepresentation of specific mutations within a subgro

150 The observed overrepresentation of specific mutations within a subgro

151 Finally, overrepresentation of specific promoter motifs in root-

152 Genetic regulatory networks include an overrepresentation of subgraphs commonly known as networ

153 ated in doxycycline-treated dTg-211 cortices overrepresentation of synaptic activity, Ca(2+) transmem

154 Sequence analysis of hTERT and hTERC showed overrepresentation of synonymous and intronic mutations

155 gs with CATH functional families through the overrepresentation of targets of those drugs in CATH fun

156 ic characteristics, with the exception of an overrepresentation of tertiary-educated women (88.7% com

157 We obtained a statistically significant overrepresentation of TF sites distributed with the main

158 f the chromosome 7 centromere and additional overrepresentation of the 7q-arm.

159 tor, is genetically associated with AD, with overrepresentation of the allele containing five copies

160 ly younger age at presentation, and a marked overrepresentation of the apolipoprotein E epsilon 4/eps

161 of up-regulated genes revealed a significant overrepresentation of the AtMYB2-binding motif (GT motif

162 We also find overrepresentation of the exon 9 missense allele Phe607

163 , yet in the SLE patients, there was a clear overrepresentation of the FcgammaRIIa-R131;FcgammaRIIIa-

164 other cytokine receptor, gp130, resulting in overrepresentation of the heterodimeric receptor for OSM

165 in-2 gene transcripts in arterial tissue and overrepresentation of the HLA-DRB1*0404 allele, indicati

166 tation and used focused IGHV repertoire with overrepresentation of the IGHV3-48, IGHV4-59, IGHV5-10-1

167 lonal IGHV gene sequences were detected with overrepresentation of the IGHV4 family and IGHV4-34 gene

168 ke gut bacterial community, characterized by overrepresentation of the key genera Exiguobacterium, Pl

169 ted by wt HSV-1, and there was a significant overrepresentation of the long terminus and underreprese

170 Overrepresentation of the paternal genome in sporadic hy

171 Overexpression models confirmed that the overrepresentation of the pathogenic PEX6 c.2578T varian

172 pographies in the tectum was found, i.e., no overrepresentation of the retina was seen in the tectum

173 Overrepresentation of the TCRBV3 gene mRNA was demonstra

174 usage of Jkappa5 segments, and a significant overrepresentation of the Vkappa1 and Vkappa4 families,

175 were assigned probabilities according to the overrepresentation of their separation distance.

176 We conclude that overrepresentation of these chromosomal regions is a cri

177 An algorithm that detects overrepresentation of these signature genes in a gene gr

178 More interestingly, overrepresentation of these TFBS was observed in hyper-/

179 Overrepresentation of these two Vbetas did not occur in

180 ng B cell development may be responsible for overrepresentation of these VH genes.

181 There is a significant (> six-fold) overrepresentation of TPMT deficiency or heterozygosity

182 tion of degranulation, including significant overrepresentation of transcripts encoding tyrosine phos

183 ctivated population and included significant overrepresentation of transcripts for mast cell protease

184 Bioinformatic classification uncovered overrepresentation of transmembrane transporters, protei

185 typically plesiomorphic, and transitions to overrepresentation of two codons occurred commonly acros

186 A significant overrepresentation of two genetic hits was detected for

187 nalysis of the unique gene set identified an overrepresentation of type I interferon (IFN)-associated

188 In silico promoter analysis indicated an overrepresentation of type-B Arabidopsis response regula

189 l power for detection of SNPs to account for overrepresentation of variants with larger effect sizes

190 imate that there is an approximately 10-fold overrepresentation of visual information.

191 d to find motifs by simultaneously using the overrepresentation property and the evolutionary conserv

192 ing motifs by simultaneously using the motif overrepresentation property and the motif evolutionary c

193 oximately 10% of MCC patients, a significant overrepresentation relative to the general population.

194 ines PC3 and DU145 have and do not have 8q24 overrepresentation, respectively.

195 ated GO terms to strengthen the detection of overrepresentation signals.

196 of these gene transcripts indicates a slight overrepresentation toward locations on the distal long a

197 In 6 of the 10 individuals with Vbeta14 overrepresentation, Vbeta14 represented >20% of the enti

198 s meeting at least one criterion for Vbeta14 overrepresentation was shown to increase in tandem with

199 The extent of this overrepresentation was stronger in mice than in humans,

200 is, and leprosy demonstrated review/protocol overrepresentation when matched with corresponding DALYs

201 sequence is analyzed at the clone level for overrepresentation within a whole-genome shotgun sequenc