ライフサイエンスコーパス: override

1 R1 localization but failed to rescue the SAC override.

2 promoted elimination of alkyl sulfoxides was overridden.

3 small cell volumes, suggesting that JAG can override a cell size checkpoint that operates in the mer

4 sponse to the physical asymmetry was able to override a dynamically generated chemical cue.

5 ing to the formation of auxin gradients that override a LAZY-independent mechanism that creates an op

6 Evidence that TGF-beta signaling can override a loss in Lrp5 has implications for patient sel

7 confirms that activation of HCN channels can override a preference for centripetal summation expected

8 Like SV40 ST, HPV16 E7 has the ability to override a quiescence block induced by mitogen deprivati

9 emonstrate that forced chromatin looping can override a stringent developmental gene expression progr

10 ow energy, it enforces mTORC1 activation and overrides a physiological response that couples energy a

11 Consequently, Ras-transformed cells override a131-induced growth arrest and enter mitosis wh

12 Strikingly, Ras activation overrides a131-induced PIK3IP1 upregulation and activate

13 e PE finding were 51.3% lower when providers overrode alerts than when they followed CDS guidelines.

14 oposal that CKS protein-dependent checkpoint override allows premalignant cells to evade oncogene str

15 and ecologically diverse bacteria, yeast can override an ancient regulatory mechanism of glucose repr

16 suggests that HAN treatment induced mitosis override, and that HAN-treated cells proceeded into S ph

17 acteristics that underlie the predicted node overrides, and compare its predictions to those of struc

18 icer-deficient CD4 T cells was sufficient to override anergy induction in WT T cells and to restore i

19 ustained cooperation, guilty repair needs to override angry retaliation.

20 Because transformed cells may override anoikis and survive after extrusion, the direct

21 Three factors cause redox control to override anthropogenic control in the case of Mo: relati

22 Central defects due to leptin deficiency may override any metabolic benefit conferred by peripheral o

23 We suggest that Paneth cell signaling overrides any direct nutrient sensing in ISCs to sculpt

24 outflow tract alignment defects ranging from overriding aorta to double-outlet right ventricle and de

25 ortic dilatation, outflow tract malrotation, overriding aorta, double outlet right ventricle, aberran

26 mice display right ventricular hypertrophy, overriding aorta, ventricular septal defects, coronary v

27 Notably, enforced expression of miR-19a overrides APC tumor suppressor activity, and knockdown o

28 Notably, Pten loss can override AR-loss effects in both basal and luminal compa

29 Nevertheless, overriding AraC resistance in AML remains an unmet medic

30 This event overrides ascending activity from dopamine neurons and,

31 that may have broad implications for how to override associative learning that has become maladaptiv

32 However, this stimulatory modification is overridden at mitosis, when elevated Plk1 activity cause

33 dephosphorylation of CENP-A and Hec1 and SAC override at high nocodazole concentrations.

34 a key regulatory element in ADP's ability to override ATP inhibition.

35 co-presented with the uninfected host odors, overriding attraction to uninfected hosts.

36 titutes the primary biophysical cue that can override biochemical signals to attenuate fusion.

37 d suggest that caspase-8-mediated cell death overrides blockade of immune signaling by YopJ to promot

38 The northernmost Peninsula was overridden by an ice sheet in the early Pliocene (approx

39 e outer segment and that this information is overridden by association with R9AP, which allows outer

40 The peripheral mechanism appears to be overridden by central control because, in contrast to am

41 uggesting that fixation potentiation was not overridden by certainty of an imminent pursuit trial but

42 First, equipoise was overridden by clinicians offering treatment recommendati

43 sable with sensible defaults that are easily overridden by custom algorithms as required.

44 ent gene transcription, and its effects were overridden by dominant negative SIRT1 (SIRT1-H355A).

45 whereas HSP90 inhibitor-induced apoptosis is overridden by ectopic MIF expression.

46 n rhythms "entrained" to the LD cycle can be overridden by entrainment to daily recurring threats.

47 tation, the heterogenous thermal signals are overridden by homogenous tactile signals.

48 ulated: cell-shape derived stresses could be overridden by imposed tissue level stresses, showing how

49 ls inducing virulence gene expression can be overridden by nutrient availability, a condition monitor

50 eedforward connectivity from LA to BL can be overridden by other BL inputs.

51 ti-proliferative effects of ERbeta1 could be overridden by overexpression of FOXM1, indicating that F

52 gly alternating miR-214 or miR-148b could be overridden by overexpression of ITGA5 or ALCAM in the sa

53 contrast, when endogenous Pcdh diversity is overridden by the expression of a single-tricluster gene

54 activity accelerates caspase activation and overrides caspase-2 suppression by nutrient abundance.

55 Forced NE targeting of BicD2 overrides Cdk1 inhibition, fully rescuing dynein recruit

56 ) was compared in patients in whom providers overrode CDS alerts (by performing CT pulmonary angiogra

57 were nearly double those seen when providers overrode CDS alerts.

58 ther, our results indicate that functionally overriding chemokine silencing at the maternal-fetal int

59 ncertain because humans can modulate or even override climatic effects on fire activity.

60 e electrophilic, tetrasubstituted sulfone to override complex-induced deprotonation.

61 ntial characteristic of human fairness is to override concerns about merit in favor of promoting the

62 This often seemed to override consideration of other potential benefits (e.g.

63 to identify coherent decadal changes and the overriding controls on planetary scales.

64 responses essential to maintain energy flux override conventional mechanisms of pubertal growth to p

65 ulinaemia and the suppression of GH release) override conventional mechanisms of pubertal growth to p

66 ed on the inputs, while allowing the user to override default parameter values.

67 pathway activation promotes tumorigenesis by overriding dependencies on the microenvironment that con

68 ng anticipated results because there were no overriding differences in financial impact.

69 that (i) change in trophic interactions can override direct climate change effect; and (ii) the demo

70 ntestinal stimulation with this moiety alone overrides disease susceptibility in mice depleted of com

71 These transcription-independent activities override DNA-intrinsic positioning and maintain uniform

72 o demonstrated that chromatin remodelers can override DNA-sequence preferences by exerting torque, an

73 Our results confirm that dams are an overriding driver of native fish species losses, irrespe

74 D propagation, their protective effects were overridden during replication of sheep prions in Tg mice

75 Influential individuals exerted an overriding effect on risk-taking by the entire group, fo

76 patient survival, suggesting that PEA15 can override ERK1/2 activation by BCAR1/BCAR3 and other upst

77 ced under stress in an ABA-dependent manner, overriding ethylene effects; and the interplay among ABA

78 he observed decline in growth rate may be an overriding factor affecting the success of this ecotype

79 e solid liquid ratio in the ASE cell was the overriding factor in obtaining high yields with both soy

80 hese data show that intrinsic properties can override fast synaptic potentials, mediate circuit recon

81 aptic connectivity that allows withdrawal to override feeding.

82 To directly test whether cognition can override fixation suppression, we alternated pursuit and

83 eversible and that lineage commitment can be overridden following severe tissue injury.

84 nt synthesis, and they establish a metabolic override for quorum-sensing-dependent regulation of RNAI

85 acteria from one mouse strain to another can override genetics and change behavior.

86 Hence, bioelectric properties can stably override genome-default target morphology, and provide a

87 mes in multiple sclerosis, which had, as its overriding goals, to review the state of the field and i

88 ling hypocotyl to the presence of obstacles, overriding gravitropism, to enable efficient circumnavig

89 of CT pulmonary angiography was 4.2% in the override group (25 of 589 studies, none with a normal d-

90 normal d-dimer level or no d-dimer testing) (override group) and those in whom providers followed Wel

91 Unexpectedly, activated STAT5 overrode Hippo-mediated inhibition and drove YAP1 to the

92 ss-responsive enhancers become activated and override homeostatic enhancers that govern lineage speci

93 which the cognitive and emotional brain may override homeostatic regulation (top-down).

94 in odd rhombomeres (r3 and r5), can largely override Hox proteins at the level of regulation of a ce

95 this, we observed that modulation of miR-155 overrides IL-12 and IL-18-mediated regulation of SHIP1 e

96 is enzyme or supplementation with L-arginine overrides immunosuppression.

97 -X-C motif) ligand 12 (CXCL12) explained the overriding immunosuppression by the FAP(+) cell: T cells

98 An unexpected, overriding impact of the C10 stereochemistry in stereose

99 pain, in which depolarized fast inactivation overrides impaired activation to produce hyperexcitabili

100 addition of even a single epitope, may be of overriding importance in achieving immune control of HIV

101 the common-garden experiment, suggesting an overriding importance of litter type.

102 These results highlight the overriding importance of MTE for predicting nutrient flo

103 our data show that this level of control is overridden in infected cells to allow constitutive activ

104 nd mitotic spindle assembly checkpoint (SAC) override in human tumor cells.

105 mplex, and accelerated mitotic exit with SAC override in the presence of spindle damage.

106 conservatively fertilized annual crops, the overriding influence of rotation phase on annual fluxes.

107 Hg cycle in aquatic environments due to its overriding influence on complexation, photochemical, and

108 the native species, which might have had an overriding influence on the chemistry of the above-groun

109 the unfolded protein response by DENV-2 can override inhibition of translation, prevent apoptosis, a

110 block of LTF appeared to be attributable to overriding inhibitory effects of p-p38 MAPK, because LTF

111 ysts are found to use steric interactions to override innate stereoelectronic effects of the allenyl

112 the role of CKS protein-dependent checkpoint override involves recovery from checkpoint-mediated arre

113 Overriding IR in an effort to lower plasma glucose level

114 regulatory networks and identify nodes whose override is necessary for control in the general case bu

115 environment around the proline catalyst can override its innate stereochemical preference to dictate

116 and that attractant stimuli shift HAMP to an overriding kinase-off signalling state to elicit counter

117 in some circumstances ecological factors may override latitudinal trends.

118 eft AVV color diameter at annulus, right AVV overriding left atrium, and LV width.

119 A second view posits an overriding limit from the atmosphere, which restricts di

120 ciated with aberrant healing (fibrosis) that overrides liver regeneration.

121 combine to modulate aging, distal regulation overrides local contribution.

122 assette was completely silenced: effectively overriding local lac promoter control.

123 ulfur is described for the first time, which overrides long-standing trifluoromethyl anion-based theo

124 at the down-going slab is decoupled from the overriding mantle wedge beneath the forearc, resulting i

125 y, ectopic RKIP expression in melanoma cells overrode MDA-9-mediated signaling, inhibiting cell invas

126 Enforced miR-155 expression overrides miR-146a-mediated repression of NF-kappaB acti

127 educe OHT risk within the constraints of the overriding need to control the primary ocular inflammato

128 coexpressed, NK cell inhibition via KIR2DL2 overrode NK cell activation via KIR2DS2.

129 HCMV induces adipocyte-like lipogenesis and overrides normal sterol feedback controls in order to ma

130 ciated VMH neurons showed that ketone bodies overrode normal FA sensing, primarily by exciting neuron

131 Protection of Chk1 by Hsp90 could be overridden not only by ablation of the NatA Nt-acetylase

132 exposure to recombinant sonic hedgehog could override Notch-induced death of cultured fetal gut mesen

133 TGFbeta dominates over Notch signaling and overrides Notch ablation-induced proliferation of prosta

134 We postulate that deliberate override of replication-coupled destruction allows antic

135 ls, as well as in other cell types, leads to override of the intra-S-phase checkpoint that blocks DNA

136 how overexpression of CKS proteins promotes override of the replication stress checkpoint.

137 the frequency of, and yield after, provider overrides of evidence-based clinical decision support (C

138 This paradox can be explained by the overriding of Ca(2+) stimulation by paracrine inhibition

139 pped trailing haptic, haptic-optic adhesion, overriding of the plunger over the optic, and trauma to

140 our intramolecular OH-F(aryl) hydrogen bonds overriding OH-OH bonding.

141 s tumor growth, enhances cell migration, and overrides oncogenic RAS-induced senescence independently

142 hreshold than the parallel circuits, but can override ongoing behavior to force a short takeoff.

143 ons of the PKR, the steric factors can often override or render possible electronic effects.

144 fire regimes but their presence can actually override, or swamp out, the effect of climate.

145 ironments that demonstrate the potential for overridden organic matter beneath glacial systems to pro

146 ctivity of the IDOL pathway in the liver can override other low-density lipoprotein receptor regulato

147 Crop phenology might override P-supply in determining the community compositi

148 red features, such as reputation systems, to override people's natural tendency to base judgments of

149 nts due to saccades, but instead reflect the overriding perception of target space during eye movemen

150 phosphorylation, and ATF4 expression, which overrides PERK/Akt-mediated adaptation and induces apopt

151 to infection by expressing behavioural fever overrides personality-related thermal choice.

152 ential for YAP nuclear localization, and can override phosphoregulation or contractility-mediated reg

153 hearing animals, virally expressed PKCgamma overrides PKCbeta to produce PTP by increasing p.

154 when one anticipates the need to inhibit and override planned actions.

155 ples of long-lived accretionary orogens, the overriding plate is subjected to episodes of crustal ext

156 In many regions, dietary change may override population growth as major driver behind land r

157 PAD-induced spiking is assumed to override presynaptic inhibition.

158 ber of adhesive and regulatory proteins, the overriding principle of a Golgi stack assembly is likely

159 5alpha-reduced steroids acutely to PNS rats overrides programming of hyperactive HPA axis responses

160 or role for miR-26 in intestinal cancer that overrides putative oncogenic activity, highlighting the

161 occurs during mitosis and is responsible for overriding quiescence.

162 Here we found that IL-1 was needed to fully override RA-mediated expression of the transcription fac

163 In most cases, however, European disturbance overrode regional climate, but in a manner that varied a

164 smaller set of promoters, suggesting that it overrides repression by RBF1/dE2F2 at a specific subset

165 Increased water availability seemingly overrides responses to reduced acid deposition, CO2 fert

166 UES contraction and relaxation were the overriding responses to esophageal water and air distens

167 the very different tissues analysed share an overriding restriction: the frequency of polygon types c

168 NKX2.5 overexpression overrides rigid phenotypes, inhibiting SMA and cell spre

169 centration from ambient seawater likely play overriding roles.

170 se and thrombin may be an initial trigger to override SAP inhibition of fibrocyte differentiation to

171 programs that promote movement and how they override scarcity and adversity as dense packs.

172 bgroups, indicating that spatial variability overrode seasonal changes in determining community compo

173 rmal physiological programs that effectively overrides secondary genetic events and a cancer collapse

174 never favors agents who use deliberation to override selfish impulses: Deliberation only serves to u

175 y, differentiated selves improve outcomes by overriding selfishness when they allow for personal regu

176 ur understanding of how food-associated cues override signals from the body to promote overeating, an

177 ermore, these changes in metabolism may even override signals inducing vessel sprouting.

178 the dmPFC might provide control signals for overriding simple heuristic learning algorithms based on

179 r annual crops, where management differences overrode simple correlations.

180 in contractility can strengthen junctions to override Snail-dependent junctional disassembly and post

181 That mechanical cues can override soluble signals suggests that their contributio

182 ogen bonding to the amino group successfully overrode steric effects and directed epoxidation to occu

183 C/EBPbeta overexpression did not override strain's inhibition of adipogenesis, which sugg

184 identify novel kinase inhibitors capable of overriding stromal-mediated resistance to TKIs, such as

185 ritical for swarming, enabling hydration and overriding surface friction.

186 effect of Klar is particularly important for overriding temperature-induced changes in motility.

187 provokes excessive IL-1beta production that overrides Th17 IL-6 dependency, amplifying the colonic T

188 ack-based framework provides realizable node overrides that steer a system toward any of its natural

189 cytokine IL17, whose pathogenic effects can override the antitumor immune response orchestrated by I

190 tion-dependent mechanism that could serve to override the autoinhibitory negative feedback regulation

191 pigenetic abnormalities is not sufficient to override the cancer genome.

192 contact (but not conformational) mutp53s can override the Cdk2 requirement to promote replication by

193 Ectopic expression of selected TFs can override the cellular identity and induce reprogramming

194 ating the unfolded protein response (UPR) to override the classic extracellular VEGF pathway.

195 tion of PLK1 caused by MYPT1 reduction could override the counteracting PP2A phosphatase, resulting i

196 faster repriming, and larger ramp currents, override the depolarizing shift of activation, to produc

197 The enantiocontrol is also shown to override the diastereoselectivity of chiral substrates.

198 of the Kdm5a target genes, is sufficient to override the differentiation block.

199 Individuals with anorexia nervosa (AN) override the drive to eat, forgoing immediate rewards in

200 ation unique among Fic domains that seems to override the effect of the inhibitory helix.

201 sms (e.g., transcription) appear to not only override the effects of S region sequence on AID targeti

202 , affect the regioselectivity and can easily override the electronic guidance.

203 charges in the signal sequence helped it to override the function of signal anchor.

204 Herein we combine these same reagents, but override the Heck pathway by employing a strong base.

205 ssion of stabilized beta-catenin was able to override the HF defects in Blimp1 mutant mice, underlini

206 sphatases and that KIR binding to HLA-C must override the hindrance that His-36 puts on KIR2DL1 self-

207 xpression, suggesting that other signals may override the IL-33-driving signal in this context.

208 A small-molecule thiol catalyst was found to override the inherent diastereoselectivity observed duri

209 The chiral catalyst can override the inherent preference for the formation of th

210 ot inhibited by TGF-beta; and its ability to override the inhibitory effects of hyperglycemia on cell

211 They override the initial specification of posterior-ventral

212 tal information system, allowed providers to override the intervention by calling the laboratory, if

213 e cancer cells that overexpress Cks1 or Cks2 override the intra-S-phase checkpoint in the presence of

214 us 1 (HSV-1), which also disrupts PML-NBs to override the intrinsic cellular defense.

215 he endo transition state and a steric effect override the intrinsic exo selectivity.

216 h photoelectron transfer agents allows us to override the intrinsic properties of an azobenzene speci

217 the ability of proinflammatory conditions to override the licensing mechanism.

218 allowing copulatory behaviours to partially override the light-induced escape responses in the male.

219 nhanced furin activity appeared to partially override the low pH-dependent nature of MERS-CoV entry.

220 Remarkably, long-term potentiation (LTP) can override the masking effect of the GFP tag.

221 kdown cells, although it was insufficient to override the mitotic arrest and cell death caused by RAB

222 ortant for valuation and choice, beliefs can override the physical presence of a potent neuroactive c

223 of Plg/Pla to both promote efferocytosis and override the prosurvival effect of LPS via annexin A1.

224 antigenic "regressor" tumor is sufficient to override the protective ability of T cells to control tu

225 e found that the syncytial mutations did not override the receptor specificity of the retargeted viru

226 We also find that IRF4 expression can override the repressive activity of STAT5.

227 ved stroma-targeted oncolytic adenovirus can override the resistance of melanoma tumors and might bec

228 he expression of proapoptotic targets and to override the resistance of RPE cells to apoptosis.

229 nvestigate whether a C-H...O interaction can override the significant trans-planar conformational pre

230 ement from the Mason-Pfizer monkey virus can override the silencing and promote transcription of chim

231 est that indirect molecular interactions may override the species-restricted activity of bacterial Pg

232 when electronic effects are strong enough to override the steric effects are BCs formed.

233 ditions, particularly if higher temperatures override the suppressive effects of high CO2 on isoprene

234 ponse to Edn2 is sufficiently potent that it overrides the activities of other homeostatic regulators

235 This reaction overrides the conventional positional selectivity patter

236 u isoforms, demonstrating that this mutation overrides the developmental regulation of exon 10 inclus

237 checkpoint (SAC) because inhibiting the SAC overrides the DNA damage-induced MI arrest.

238 By contrast, calcium-dependent CaM binding overrides the effects of autophosphorylation and activat

239 receptor-mediated synaptic transmission that overrides the effects of KAR LTD on the cellular respons

240 In doubly bound MTs, peloruside overrides the heterogeneity induced by Taxol binding.

241 mpensation directly, but rather its activity overrides the high level of histone acetylation and coun

242 anslation is also altered so that it largely overrides the hyperaccumulation of transcripts, and as a

243 atalyst significantly enhances or completely overrides the inherent regioselective acetalization prof

244 In addition, this template overrides the intrinsic electronic and steric biases as

245 pecific CD44 standard (CD44s) splice isoform overrides the loss of hnRNPM and permits EMT and metasta

246 by cell cycle-dependent phosphorylation that overrides the mating pheromone-induced phosphorylation t

247 Here we show that B7 deprivation in mice overrides the necessity for Tregs in averting systemic a

248 However, in non-Pd GPI-APs, the ectodomain overrides the Pd targeting function of the GPI signal an

249 s been shown that CKS protein overexpression overrides the replication stress checkpoint, promoting c

250 actors and show that mutation of this region overrides the repression of MBF- and SBF-regulated genes

251 ingly, however, the presence of human fibrin overrides the species-restricted action of SUPA.

252 upon elongation of the spindle into the bud, overrides the SPOC.

253 taste and/or smell of novel bacteria, which overrides the stimulatory effect of familiar bacteria on

254 D4-dependent transcription, and consequently overrides the TGF-beta-dependent checkpoint for PTEN-nul

255 tant RAEB/AML constitutes a related disorder overriding the artificial separation between AML and MDS

256 a "hard stop" that prevents a clinician from overriding the CCDS without outside consultation, as wel

257 hat dock and fuse with early endosomes, thus overriding the default pathway to the Golgi.

258 at genetic regulation can create patterns by overriding the default rule.

259 f a benzylic dimethylamine and hydrosilanes, overriding the established directing-group effects obser

260 g to the heme prevents P450cam from opening, overriding the influence exerted by Pdx binding.

261 induce neural crest around the neural plate, overriding the normal neural plate border limit of the e

262 n oxazoline-based directing group capable of overriding the poisoning effect of a wide range of heter

263 n induced reactivation of disease pathology, overriding the protective adaptive immune response.

264 3 integrin-dependent C2C12 cell spreading by overriding the soft signal of the biomaterial and impact

265 with the striatum when subjects successfully overrode the decoy effect and made unbiased choices.

266 vated the Hsp27 phosphorylation and possibly overrode the direct Hsp27 inhibitory effects, which made

267 wn-regulation and enforced expression of E2A overrode the inhibitory effects of forskolin on megakary

268 into the peritoneal cavity during infection overrode the protection provided by indomethacin and res

269 ival gene BCL2 in mouse embryonic stem cells overrode the requirement of serum factors and feeder cel

270 nally, in in vitro settings, ROL and Bt2cAMP overrode the survival-inducing effect of LPS in human ne

271 etabolic effects of iron limitation but also overrode the transcription of iron-regulated genes.

272 ral exchange among these communities largely overrode the visible signal of the prior millennia of cu

273 states of arousal, although the network can override their contribution to adjust its activity for n

274 kade of aversive acquisition enables them to override their prior aversive memory with an appetitive

275 ty and cap-dependent mRNA translation, which overrides their inhibition by hypoxia and facilitates tu

276 There was one overriding theme formulated: Vulnerability at the junctu

277 y protect against some chronic diseases, the overriding theme of studies performed to date is that pe

278 ded objects caused "bottom-up" mechanisms to override these "top-down" attentional enhancements.

279 Secondary genetic alterations override these barriers and promote intermediate or over

280 The genetic alterations that override these controls in endocrine tumors often are no

281 ed whether pharmacological activation of PDC overrides these diet-induced changes.

282 code switching, or if the cost of switching overrides these lexico-semantic and sentence context fac

283 antimicrobials or gnotobiotic germ-free mice overrides these protective benefits.

284 elding and increased NTRcargo surface-ratios override this inhibition.

285 d identifies novel cotreatment strategies to override this survival advantage.

286 ng is tonically inhibited by NPY, but stress overrides this autocrine negative feedback loop.

287 olesterol, or by providing an inhibitor that overrides this cholesterol activation.

288 Ectopic expression of membrane-anchored Pak1 overrides this spatial specification of dendritogenesis,

289 ermed the "universal FGFR ligand" because it overrides this specificity barrier.

290 However, activation of iNKT cells overrides this survival signal, causing marked apoptosis

291 tors PKC412 and dasatinib were also found to override TKI resistance in NI-1 cells, and produced grow

292 assay, we identified trans-acting Terminator Override (TOV) genes that operate this terminator.

293 pecific gene profile that can be temporarily overridden under lymphopenic conditions but is inevitabl

294 To investigate the consequence of overriding uniparental inheritance, we generated mice co

295 tion rather than from a control process that overrides valuation mechanisms.

296 r with the objective of a decent society, as overriding values beyond health to other domains of huma

297 may be directed against "stealth" epitopes, overriding viral chicanery.

298 here cognitive control processes allow us to override well-learned stimulus-response (S-R) associatio

299 Most overrides were due to the lack of d-dimer testing in pat

300 tivation, the effects of enzyme activity are overridden, with pDCs becoming resistant to GCs and full