ライフサイエンスコーパス: overtly

1 e overexpressing hMT torsinA did not develop overtly abnormal motor behavior.

2 strate that the C-terminal mutation does not overtly affect APP processing and amyloid pathology.

3 lar knockdown of Cyp26a1 or Cyp26c1 does not overtly affect cardiovascular development, double Cyp26a

4 Notch does not overtly affect cell cycle entry or progression of CD4(+)

5 ducts (type I latency) that are not known to overtly affect cell growth.

6 Mutations in the B9 genes do not overtly affect cilia formation unless they are in combin

7 ld-type mice, this allele of Cdc25A does not overtly affect erythropoiesis; however, when this allele

8 ites in vitro, at concentrations that do not overtly affect mammalian host cells.

9 obal deletion of either Lrp5 or Lrp6 did not overtly affect osteoblast differentiation in the mouse e

10 d increase in postsynaptic activity does not overtly affect postsynaptic morphology but causes transi

11 progression in satellite cells, but did not overtly affect the myogenic program.

12 ult Muller glia in undamaged retina does not overtly affect their phenotype; however, when the retina

13 ), 25 mildly symptomatic (CDR = 0.5), and 33 overtly affected (CDR > 0.5) autosomal dominant Alzheime

14 Blood taken from overtly affected animals was assayed for antibodies to c

15 pithelial barrier function, however, was not overtly affected by brushing, despite the observed indiv

16 leading to differentiation of the CNS is not overtly affected by exposure to MeHg.

17 lveolar development during pregnancy was not overtly affected by loss of Gli2 function.

18 d with SNCA dosage and does not appear to be overtly affected by the presence of other genes in the m

19 owth of the falcipain 1 minus clones was not overtly affected, and they produced morphologically norm

20 desmin filaments in the cardiomyocytes were overtly affected, myofibril alignment was significantly

21 obe (IL) while the anterior lobe (AL) is not overtly affected.

22 remained constant, and MF alignment was not overtly affected.

23 s the formation of the atrial septum without overtly affecting atrial chamber formation.

24 gests that p19(ARF) can activate p53 without overtly affecting Mdm2 subcellular localization.

25 Like other ataxias, SCA2 most overtly affects Purkinje cells (PCs) in the cerebellum.

26 oximately one per genome per generation, not overtly altered across several DNA repair deficiencies o

27 llular and soluble CD127 expressions) is not overtly altered and remains activable in septic patients

28 In contrast, heterozygous mice are overtly and histologically indistinguishable from contro

29 Cells derived from the overtly aphenotypical model of X-linked Emery-Dreifuss m

30 stined for programmed cell death but not yet overtly apoptotic.

31 IL-10-mediated inhibitory activity was not overtly associated with cytotoxicity or induction of apo

32 e hippocampal region is involved not just in overtly associative tasks but more broadly in the recoll

33 EMCV 30/87-infected macaques remained overtly asymptomatic for 45 days, despite extensive myoc

34 c failure, whereas the rest of the pigs were overtly asymptomatic for as long as 90 days postinfectio

35 B6.yaa mice are not overtly autoimmune, but the addition of Sle1, which cont

36 ble of recognizing self antigens but are not overtly autoreactive.

37 out work in other areas which demands a more overtly biomedical approach.

38 ovascular disease and significantly but less overtly by renal dysfunction.

39 Antigen did not overtly cause action potential generation except in one

40 by TNF show reduced TEER, but do so without overtly changing their cell junctions, cell shape, or cy

41 While he does not overtly claim that social preferences are only by-produc

42 vidence from nonhuman primates and humans is overtly concerning, it lacks clinical verification.

43 number of structural differences in several overtly conserved homologous regions and more precisely

44 t that memory bystander CD8+ T cells may not overtly contribute to pathology in the absence of antige

45 esponse hand in an even larger proportion of overtly correct trials, revealing covert response impuls

46 tatin inhibited Ras processing without being overtly cytotoxic.

47 d injured soldiers under stressful and often overtly dangerous situations.

48 In summary, plasma Abeta is overtly decreased during the dementia stage of AD indica

49 Although overtly deleterious mutations in MMR genes can clearly b

50 nondeletional form of tolerance that is not overtly dependent on the prototypic Th1 and Th2 cytokine

51 ic ovine PrP expressed in Drosophila was not overtly detrimental to the flies.

52 w concentrations of proteinase K, it was not overtly detrimental to the flies.

53 weaning, the male Nkx2.2-repressor mice are overtly diabetic and all Nkx2.2-repressor transgenic mic

54 and developed early hyperglycemia, with 85% overtly diabetic by 6 months.

55 vated blood glucose levels at birth and were overtly diabetic by weaning.

56 several therapies have successfully treated overtly diabetic mice.

57 ls induced chimerism without causing GVHD in overtly diabetic NOD mice conditioned with anti-CD3/CD8

58 ontinuous oral FTY720 (3 mg/kg) treatment in overtly diabetic NOD mice led to complete reversal of di

59 Overtly diabetic NOD mice received intravenous injection

60 In a pilot study, overtly diabetic NOD mice were cured by co-transplantati

61 Transient treatment of overtly diabetic NOD mice with ALS and exendin-4 achieve

62 Treatment of overtly diabetic NOD mice with anti-lymphocyte serum (AL

63 ycemia and immune tolerance to beta cells in overtly diabetic NOD mice, and none have demonstrably en

64 purified from the pancreatic lymph nodes of overtly diabetic NOD mice, mcDCs break peripheral T cell

65 to diabetes transferred by splenocytes from overtly diabetic NOD mice.

66 s incapable of preventing islet rejection in overtly diabetic NOD recipient mice.

67 itates regeneration of beta-cell function in overtly diabetic nonobese diabetic (NOD) mice.

68 A(+) patients but not in control subjects or overtly diabetic patients, suggesting that inflammation

69 was administered late during pathogenesis to overtly diabetic recipients.

70 lucose and glycosylated hemoglobin and seven overtly diabetic subjects were studied as were six nondi

71 uced obesity caused Skp2(-/-) mice to become overtly diabetic, because beta cell growth in the absenc

72 By 26 weeks of age, IDMs are overtly diabetic.

73 ge, 40% of these double heterozygotes become overtly diabetic.

74 on only became manifest when subjects became overtly diabetic.

75 e scanner to assess the ability to recognize overtly different intensities of disgust.

76 ns not favoring differentiation, they do not overtly differentiate but still activate expression of m

77 l fates generally fail to migrate and do not overtly differentiate.

78 Three of these neurons are overtly dimorphic and identify a male-specific neuropil

79 Infection was detected in overtly diseased and seemingly healthy animals.

80 5 when many tissues are assembling, does not overtly disrupt development as assessed by proteomic ana

81 The anatomy of the cerebellum is not overtly disturbed, and excitatory synaptic transmission

82 within hindbrain structures will produce an overtly dystonic animal.

83 The overtly electrostatic character of HA binding in Lyve-1

84 tive during wakeful rest when people are not overtly engaged with a sensory stimulus or externally or

85 hose with and those without current comorbid overtly expressed irritability/anger.

86 nce of morphologically distinct stages, from overtly featureless endoderm, through organ primordia to

87 and connectivity patterns while participants overtly generated words according to nonmnemonic (phonem

88 Unlike many pathogens that are overtly harmful to their hosts, Mycobacterium tuberculos

89 The time required to overtly heal wounds was similar in fibrinogen-deficient

90 Unlike overtly healthy Y3 mice, all Y3/CD103(-/-) mice rapidly

91 n at predicted Mendelian frequencies, appear overtly healthy, and contain normal numbers and frequenc

92 leaving the ICU for complex surgical cases, overtly high-risk patients, or the treatment of severe p

93 Evening types had overtly higher 24 h urinary epinephrine and morning plas

94 gmatised groups are currently the targets of overtly hostile evaluation and treatment by others (e.g.

95 -old ZDF rats in comparison with 12-week-old overtly hyperglycemic animals and, as controls, Zucker l

96 Blood glucose levels rose to overtly hyperglycemic levels in the obese group, stabili

97 he storage protein knockdown (SP-) seeds are overtly identical to the wild type, maturing to similar

98 nitial goal of this study was to define when overtly identifiable VSMCs were first associated with th

99 hough the items presented were identical and overtly identified in each task.

100 gic bronchopulmonary aspergillosis (ABPA) in overtly immunocompetent and atopic individuals, respecti

101 sorders in the PyN synthetic pathway are not overtly immunodeficient militate against this hypothesis

102 iver foci in X-CGD and iNOS KO mice was also overtly impaired at wk 2.

103 mal in 63%, borderline decreased in 15%, and overtly impaired in 22%.

104 or activity were additionally more common in overtly impaired mutation carriers.

105 rs can diminish T(reg) cell function without overtly impairing T effector cell responses or inducing

106 e and was likely the reason why BP increased overtly in these animals.

107 We found that antibiotic treatment did not overtly increase the parasite burden but significantly l

108 is often out of proportion to the amount of overtly infarcted tissue, and how decreased delivery of

109 oninflammatory, nonreplicating antigen or an overtly inflammatory replicating antigen, CD8(+) cytotox

110 ified stepwise during analysis, this did not overtly interfere with the SERS signals.

111 dents such as mice and rats, the dLGN is not overtly laminated, the retinal terminals from the two ey

112 ong with regions that will eventually become overtly lesion containing and areas of remyelination.

113 against tumor formation but is disabled when overtly malignant cells emerge.

114 rker is known to distinguish borderline from overtly malignant neoplasms.

115 emonstrate transformation of human ECs to an overtly malignant phenotype.

116 e these barriers and promote intermediate or overtly malignant tumors along distinct progression traj

117 cal Rb-negative cells appear and progress to overtly malignant tumors earlier.

118 with acute lymphoblastic leukemia rarely are overtly malnourished, which makes this population ideal

119 has been applied to many simple, monogenic, overtly Mendelian human traits, with great success.

120 Although not overtly morphologically complex, molecular investigation

121 and non-native speakers of English who were overtly naming pictures of objects and reading their wri

122 ansion has evolved into a neoplastic-like or overtly neoplastic disorder, perhaps contributing to its

123 Furthermore, in overtly NOD mice, these cells are able to significantly

124 urine encephalomyelitis virus, and they made overtly normal Ab responses to a variety of antigens.

125 Secretin receptor-deficient mice are overtly normal and fertile; however, synaptic plasticity

126 Adult punc-deficient mice were overtly normal and had normal hearing.

127 mice lacking Rac1 or RhoA in podocytes were overtly normal and lived to adulthood.

128 These mice showed overtly normal cardiac structure/function under the basa

129 b1 hypomorphic mice are viable, fertile, and overtly normal despite weakened mitotic checkpoint activ

130 ice lacking one copy of the Map2k7 gene were overtly normal in a variety of behavioural tests, these

131 uration, and heavy chain class switching are overtly normal in A-myb-deficient mice.

132 ams from line D nurse their pups and display overtly normal mammary development, line A shows some im

133 alities with perinatal lethality, viable and overtly normal Tet1/Tet2-deficient mice were also obtain

134 eta-deficient mice were viable, fertile, and overtly normal well into adulthood, but displayed a 80%

135 increase in Th2 cytokine production but were overtly normal with respect to parasite infection and pa

136 h the expected Mendelian frequency, appeared overtly normal, and were fertile.

137 Conditionally mutant Dab2(-/-) mice are overtly normal, but have reduced clathrin-coated pits in

138 le a CPEB knockout (KO) mouse is sterile but overtly normal, embryo fibroblasts derived from this mou

139 While mice deficient in this domain are overtly normal, mice lacking Ron signaling have an alter

140 e, which were viable, fertile, and otherwise overtly normal, showed an increase in basal ERK1/2 phosp

141 ugh complexin 2 knockout (Cplx2-/-) mice are overtly normal, they show significant abnormalities in c

142 Mutant mice were overtly normal, viable, and fertile on the C57BL/6 backg

143 lpha 1A/C knockout (KO) mice were viable and overtly normal.

144 Homozygous knockout mice are overtly normal.

145 B- and T-cell development are overtly normal.

146 Mice homozygous for a Herc4 mutation are overtly normal; however, overall the males produce litte

147 ed concrete noun and generating verbs either overtly or covertly in response to the auditorily presen

148 providing an attachment substratum for more overtly pathogenic organisms such as Porphyromonas gingi

149 otential, from commensal to opportunistic to overtly pathogenic.

150 stort discussion of many topics that are not overtly political, including behavioral genetics and evo

151 and multiplicities, the observed fraction of overtly polyclonal heterotypic adenomas was significantl

152 alyses that relate the observed frequency of overtly polyclonal heterotypic tumors to the geometry of

153 en these 2 regions during passive viewing of overtly presented affective stimuli unrelated to trauma

154 -181a resulted in maturation of T cells that overtly reacted toward these erstwhile positively select

155 xes develop into mature T cells that are not overtly reactive to those same complexes.

156 genetic background, mutant heavy chains were overtly recessive and hypomorphic: each was able to subs

157 rable to legal challenges and that would not overtly rely upon biblical literalism.

158 the specific sites of virus assembly without overtly removing it from the cell surface and that lipid

159 f similar activation increases in tasks that overtly require manipulation by instructing participants

160 e investigated the policy that humans use to overtly sample information in a perceptual decision task

161 However, this region is not overtly segmented in amphioxus, raising the question of

162 Multiple studies highlighted the overtly self-reactive T cell repertoire in the diabetes-

163 n areas that directs saccadic eye movements, overtly shifting both gaze and attention from position t

164 ndothelial cell (EC) specification, which is overtly similar to the ability of Wnt signaling to direc

165 PSC and cancer cell metabolism are overtly similar, with metabolite levels influencing epig

166 r inflammatory cells, and resident cells can overtly stimulate nerve endings, cause long-lasting chan

167 mbers are reduced, these self-ligands become overtly stimulatory and cause naive T cells to prolifera

168 iruses, and influenza B viruses but were not overtly susceptible to infection with human seasonal H3N

169 these cells to dystonic-like movements in an overtly symptomatic animal model.

170 a genetic model of primary dystonia that is overtly symptomatic, and link torsinA hypofunction to ne

171 ities in spatially distributed brain regions overtly synchronize in narrow frequency bands is critica

172 inth Schistosoma mansoni, the Th response is overtly Th2-like, creating an environment rich in IL-4.

173 atients do not retain the ability to respond overtly to command and it is becoming increasingly accep

174 These COX-2 and ODC inhibitor drugs were not overtly toxic at the doses used when administered to mic

175 In contrast, an overtly toxic concentration of cadmium (50 microM) rapid

176 Unlike many pathogens that are overtly toxic to their hosts, the primary virulence dete

177 be formation at concentrations that were not overtly toxic, as demonstrated by 3-(4,5-dimethylthiazol

178 pressing SV40T, hTERT and N-ras exhibited an overtly transformed phenotype; forming very large coloni

179 NOD mice, autoantibody-positive (AA(+)) and overtly type 1 diabetic (T1D) patients during the progre

180 ass switching and Ab affinity maturation are overtly unaltered.

181 g a pattern of double segment periodicity in overtly unsegmented tissue.

182 e 620 adults older than 60 years with acute, overtly unstable ankle fracture.

183 matic tricuspid regurgitation and may not be overtly visualized by echocardiography.

184 880 bacillary units, all of the rabbits were overtly well until they were sacrificed at 33 weeks.

185 to be angry with others and to express anger overtly, were not.

186 he C. elegans Skp2 ortholog, skpt-1, appears overtly wild type with the exception of an impenetrant g

187 hose patients who followed commands, whether overtly with behavior or covertly with functional neuroi